KEGG T03086: 103012537

KEGG Orthology (KO) [BR:bacu00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103012537 (MAP2K6)
   04015 Rap1 signaling pathway
    103012537 (MAP2K6)
   04668 TNF signaling pathway
    103012537 (MAP2K6)
09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    103012537 (MAP2K6)
09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    103012537 (MAP2K6)
   04664 Fc epsilon RI signaling pathway
    103012537 (MAP2K6)
  09152 Endocrine system
   04912 GnRH signaling pathway
    103012537 (MAP2K6)
   04935 Growth hormone synthesis, secretion and action
    103012537 (MAP2K6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    103012537 (MAP2K6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    103012537 (MAP2K6)
09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    103012537 (MAP2K6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    103012537 (MAP2K6)
   05022 Pathways of neurodegeneration - multiple diseases
    103012537 (MAP2K6)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    103012537 (MAP2K6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    103012537 (MAP2K6)
   05135 Yersinia infection
    103012537 (MAP2K6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    103012537 (MAP2K6)
   05161 Hepatitis B
    103012537 (MAP2K6)
   05163 Human cytomegalovirus infection
    103012537 (MAP2K6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    103012537 (MAP2K6)
   05169 Epstein-Barr virus infection
    103012537 (MAP2K6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    103012537 (MAP2K6)
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:bacu01001]
    103012537 (MAP2K6)
Enzymes [BR:bacu01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     103012537 (MAP2K6)
Protein kinases [BR:bacu01001]
Serine/threonine kinases: STE group
  STE7 family
   103012537 (MAP2K6)

SSDB

Motif

Pfam:

Pkinase PK_Tyr_Ser-Thr Kinase-like Seadorna_VP7 Pkinase_fungal CLP1_P Choline_kinase DUF4344 APH

Other DBs

NCBI-GeneID:

103012537

NCBI-ProteinID:

XP_007185643

UniProt:

A0A384AEA6

LinkDB

Position

AA seq 368 aa
MPNSQQGEKGRSSWVKRIGSLILTFPPGLVKNLTRDLSLHLGSSAQPGDWSLSFTAVLVG
GKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIVELGRGAYG
VVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALFREGDV
WICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNV
LINTLGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDIWSLGI
TMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADEFSDEFADFTSQCLKKNSKERPTY
PELMGNKT

NT seq 1107 nt +upstreamnt +downstreamnt
atgccgaactcccagcagggagaaaagggcaggtcttcctgggtaaagagaattggcagc
cttatactgacatttccccccggactggtgaaaaacctcacccgtgacctcagcctgcac
ttgggaagctctgctcagcctggtgactggagcttgtcattcacagccgtcctggtagga
ggcaagaagcgaaaccctggccttaaaatcccgaaagaagcatttgaacaacctcagacc
agttccacgccacctcgagatttagactccaaagcttgcatttctattggaaatcagaac
tttgaggtgaaggcggatgacctggagcctatagtggagctgggccggggggcgtacggg
gtggtggagaagatgcggcatgtgcccagcgggcagatcatggcggtgaagcggatccgg
gccacagtaaatagccaggagcagaaaaggttactgatggatctggatatttccatgagg
accgtggactgtccttttacggtcaccttttatggcgcactcttccgtgagggggatgtc
tggatctgcatggagctcatggacacgtccctagataaattctacaaacaagtgattgat
aaaggccaaacaattccagaggacatcttagggaaaatagcagtttctattgtaaaagca
ttagaacatttacacagtaagctctctgtcattcatcgagatgtcaagccttccaatgtg
ctcatcaacaccctgggccaggtgaagatgtgcgattttgggatcagcggctaccttgtt
gactctgtcgctaaaactattgatgcaggatgcaaaccgtacatggcccccgagagaata
aacccagagctcaaccagaagggatacagcgtgaagtccgacatttggagtctgggcatc
accatgatcgagctggccatccttcggtttccctatgactcgtggggaaccccttttcag
cagctcaaacaggtggtggaggagccgtcgccacaactccccgcagacgagttctccgac
gagtttgccgacttcacctcgcagtgcttgaagaagaattccaaagaaaggccaacatat
ccagagcttatgggaaataaaacctga

Balaenoptera acutorostrata scammoni (minke whale): 103019100

Entry

103019100 CDS T03086

Gene name

MAP2K3

Definition

(RefSeq) mitogen-activated protein kinase kinase 3

K04432

mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]

Organism

bacu Balaenoptera acutorostrata scammoni (minke whale)

Pathway

bacu04010

MAPK signaling pathway

bacu04015

Rap1 signaling pathway

bacu04218

Cellular senescence

bacu04620

Toll-like receptor signaling pathway

bacu04664

Fc epsilon RI signaling pathway

bacu04668

TNF signaling pathway

bacu04714

Thermogenesis

bacu04750

Inflammatory mediator regulation of TRP channels

bacu04912

GnRH signaling pathway

bacu04935

Growth hormone synthesis, secretion and action

bacu05014

Amyotrophic lateral sclerosis

bacu05022

Pathways of neurodegeneration - multiple diseases

bacu05132

Salmonella infection

bacu05135

Yersinia infection

bacu05145

Toxoplasmosis

bacu05161

Hepatitis B

bacu05169

Epstein-Barr virus infection

bacu05170

Human immunodeficiency virus 1 infection

bacu05235

PD-L1 expression and PD-1 checkpoint pathway in cancer

Brite

KEGG Orthology (KO) [BR:bacu00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103019100 (MAP2K3)
   04015 Rap1 signaling pathway
    103019100 (MAP2K3)
   04668 TNF signaling pathway
    103019100 (MAP2K3)
09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    103019100 (MAP2K3)
09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    103019100 (MAP2K3)
   04664 Fc epsilon RI signaling pathway
    103019100 (MAP2K3)
  09152 Endocrine system
   04912 GnRH signaling pathway
    103019100 (MAP2K3)
   04935 Growth hormone synthesis, secretion and action
    103019100 (MAP2K3)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    103019100 (MAP2K3)
  09159 Environmental adaptation
   04714 Thermogenesis
    103019100 (MAP2K3)
09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    103019100 (MAP2K3)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    103019100 (MAP2K3)
   05022 Pathways of neurodegeneration - multiple diseases
    103019100 (MAP2K3)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    103019100 (MAP2K3)
   05135 Yersinia infection
    103019100 (MAP2K3)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    103019100 (MAP2K3)
   05161 Hepatitis B
    103019100 (MAP2K3)
   05169 Epstein-Barr virus infection
    103019100 (MAP2K3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    103019100 (MAP2K3)
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:bacu01001]
    103019100 (MAP2K3)
Enzymes [BR:bacu01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     103019100 (MAP2K3)
Protein kinases [BR:bacu01001]
Serine/threonine kinases: STE group
  STE7 family
   103019100 (MAP2K3)

SSDB

Motif

Pfam:

Pkinase PK_Tyr_Ser-Thr Kinase-like Seadorna_VP7 Pkinase_fungal APH RIO1 Choline_kinase

Other DBs

NCBI-GeneID:

103019100

NCBI-ProteinID:

XP_007174262

UniProt:

A0A383ZGP3

LinkDB

Position

AA seq 347 aa
MESPAASQPAGVPASKGKSRRKKDLRISCVSKPPAPSPTPPRNLDSRAFITIGDRNFEVE
ADDLVAISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDVNMRTVDC
FYTVTAIPDAHVQGDVWICMELMDTSLDKFYRKVLDKDMTIPEDILGEIAVSIVRALEHL
HSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPEL
NQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPADRFSPEFVD
FTAQCLRKNPAERMSYLELMEHPFFTSHKTKKTDIAAFVKEILGEDS

NT seq 1044 nt +upstreamnt +downstreamnt
atggaatctcctgccgcgagccagcccgccggggtgcccgcgtccaaaggaaagtccagg
aggaagaaggatttacgaatctcctgcgtgtccaagccgccggcgcccagccccacgccc
ccccggaacctggactcccgggccttcatcaccatcggggacaggaactttgaggtggag
gcggatgacctggtcgccatctcggagctgggccggggcgcctacggggtagtggagaag
gtgcggcacgcccagagtggtaccatcatggccgtgaagcgcatccgggccaccgtgaac
tcgcaggagcagaagcgcctgctcatggacttggacgtgaacatgcgcacggtcgactgc
ttctacaccgtgacagcgattccggatgcccacgtgcagggagacgtgtggatctgcatg
gagctcatggacacatccctggacaagttctaccggaaggtgctggacaaggacatgacg
atcccggaggacattctcggggaaatcgctgtatctattgtgagggccctggagcacctg
cacagcaagctgtccgtgatccacagagacgtgaagccgtccaacgtcctcatcaacaag
gagggccacgtgaagatgtgcgactttgggatcagtggctacctggtggattccgtggcc
aagacgatggatgccggctgcaagccctacatggcccctgagaggatcaacccggagctg
aaccagaaaggctacaatgtcaagtccgacgtctggagcctcggcatcaccatgatcgag
atggccatcctgcggtttccttatgagtcctgggggaccccgttccagcagctgaagcag
gtggtggaggagccgtccccgcagctcccagctgaccgcttctcccccgagtttgtggac
ttcactgcacagtgcctgagaaagaaccctgcggaacgcatgagctacctggagctgatg
gaacaccctttcttcacctcgcacaaaaccaagaagaccgacatcgctgcctttgtgaag
gagatcctgggagaggactcgtag

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