Balaenoptera acutorostrata scammoni (minke whale): 103014337
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Entry
103014337 CDS
T03086
Gene name
RAF1
Definition
(RefSeq) Raf-1 proto-oncogene, serine/threonine kinase
KO
K04366
RAF proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
bacu
Balaenoptera acutorostrata scammoni (minke whale)
Pathway
bacu01521
EGFR tyrosine kinase inhibitor resistance
bacu01522
Endocrine resistance
bacu04010
MAPK signaling pathway
bacu04012
ErbB signaling pathway
bacu04014
Ras signaling pathway
bacu04015
Rap1 signaling pathway
bacu04022
cGMP-PKG signaling pathway
bacu04024
cAMP signaling pathway
bacu04062
Chemokine signaling pathway
bacu04068
FoxO signaling pathway
bacu04071
Sphingolipid signaling pathway
bacu04072
Phospholipase D signaling pathway
bacu04140
Autophagy - animal
bacu04150
mTOR signaling pathway
bacu04151
PI3K-Akt signaling pathway
bacu04210
Apoptosis
bacu04218
Cellular senescence
bacu04270
Vascular smooth muscle contraction
bacu04360
Axon guidance
bacu04370
VEGF signaling pathway
bacu04371
Apelin signaling pathway
bacu04510
Focal adhesion
bacu04540
Gap junction
bacu04550
Signaling pathways regulating pluripotency of stem cells
bacu04613
Neutrophil extracellular trap formation
bacu04625
C-type lectin receptor signaling pathway
bacu04630
JAK-STAT signaling pathway
bacu04650
Natural killer cell mediated cytotoxicity
bacu04660
T cell receptor signaling pathway
bacu04662
B cell receptor signaling pathway
bacu04664
Fc epsilon RI signaling pathway
bacu04666
Fc gamma R-mediated phagocytosis
bacu04720
Long-term potentiation
bacu04722
Neurotrophin signaling pathway
bacu04726
Serotonergic synapse
bacu04730
Long-term depression
bacu04810
Regulation of actin cytoskeleton
bacu04910
Insulin signaling pathway
bacu04912
GnRH signaling pathway
bacu04914
Progesterone-mediated oocyte maturation
bacu04915
Estrogen signaling pathway
bacu04916
Melanogenesis
bacu04917
Prolactin signaling pathway
bacu04919
Thyroid hormone signaling pathway
bacu04921
Oxytocin signaling pathway
bacu04926
Relaxin signaling pathway
bacu04928
Parathyroid hormone synthesis, secretion and action
bacu04929
GnRH secretion
bacu04935
Growth hormone synthesis, secretion and action
bacu05010
Alzheimer disease
bacu05022
Pathways of neurodegeneration - multiple diseases
bacu05034
Alcoholism
bacu05132
Salmonella infection
bacu05152
Tuberculosis
bacu05160
Hepatitis C
bacu05161
Hepatitis B
bacu05163
Human cytomegalovirus infection
bacu05164
Influenza A
bacu05165
Human papillomavirus infection
bacu05167
Kaposi sarcoma-associated herpesvirus infection
bacu05170
Human immunodeficiency virus 1 infection
bacu05200
Pathways in cancer
bacu05205
Proteoglycans in cancer
bacu05206
MicroRNAs in cancer
bacu05210
Colorectal cancer
bacu05211
Renal cell carcinoma
bacu05212
Pancreatic cancer
bacu05213
Endometrial cancer
bacu05214
Glioma
bacu05215
Prostate cancer
bacu05218
Melanoma
bacu05219
Bladder cancer
bacu05220
Chronic myeloid leukemia
bacu05221
Acute myeloid leukemia
bacu05223
Non-small cell lung cancer
bacu05224
Breast cancer
bacu05225
Hepatocellular carcinoma
bacu05226
Gastric cancer
bacu05230
Central carbon metabolism in cancer
bacu05231
Choline metabolism in cancer
bacu05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
bacu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
103014337 (RAF1)
04012 ErbB signaling pathway
103014337 (RAF1)
04014 Ras signaling pathway
103014337 (RAF1)
04015 Rap1 signaling pathway
103014337 (RAF1)
04370 VEGF signaling pathway
103014337 (RAF1)
04371 Apelin signaling pathway
103014337 (RAF1)
04630 JAK-STAT signaling pathway
103014337 (RAF1)
04068 FoxO signaling pathway
103014337 (RAF1)
04072 Phospholipase D signaling pathway
103014337 (RAF1)
04071 Sphingolipid signaling pathway
103014337 (RAF1)
04024 cAMP signaling pathway
103014337 (RAF1)
04022 cGMP-PKG signaling pathway
103014337 (RAF1)
04151 PI3K-Akt signaling pathway
103014337 (RAF1)
04150 mTOR signaling pathway
103014337 (RAF1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
103014337 (RAF1)
09143 Cell growth and death
04210 Apoptosis
103014337 (RAF1)
04218 Cellular senescence
103014337 (RAF1)
09144 Cellular community - eukaryotes
04510 Focal adhesion
103014337 (RAF1)
04540 Gap junction
103014337 (RAF1)
04550 Signaling pathways regulating pluripotency of stem cells
103014337 (RAF1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
103014337 (RAF1)
09150 Organismal Systems
09151 Immune system
04613 Neutrophil extracellular trap formation
103014337 (RAF1)
04625 C-type lectin receptor signaling pathway
103014337 (RAF1)
04650 Natural killer cell mediated cytotoxicity
103014337 (RAF1)
04660 T cell receptor signaling pathway
103014337 (RAF1)
04662 B cell receptor signaling pathway
103014337 (RAF1)
04664 Fc epsilon RI signaling pathway
103014337 (RAF1)
04666 Fc gamma R-mediated phagocytosis
103014337 (RAF1)
04062 Chemokine signaling pathway
103014337 (RAF1)
09152 Endocrine system
04910 Insulin signaling pathway
103014337 (RAF1)
04929 GnRH secretion
103014337 (RAF1)
04912 GnRH signaling pathway
103014337 (RAF1)
04915 Estrogen signaling pathway
103014337 (RAF1)
04914 Progesterone-mediated oocyte maturation
103014337 (RAF1)
04917 Prolactin signaling pathway
103014337 (RAF1)
04921 Oxytocin signaling pathway
103014337 (RAF1)
04926 Relaxin signaling pathway
103014337 (RAF1)
04935 Growth hormone synthesis, secretion and action
103014337 (RAF1)
04919 Thyroid hormone signaling pathway
103014337 (RAF1)
04928 Parathyroid hormone synthesis, secretion and action
103014337 (RAF1)
04916 Melanogenesis
103014337 (RAF1)
09153 Circulatory system
04270 Vascular smooth muscle contraction
103014337 (RAF1)
09156 Nervous system
04726 Serotonergic synapse
103014337 (RAF1)
04720 Long-term potentiation
103014337 (RAF1)
04730 Long-term depression
103014337 (RAF1)
04722 Neurotrophin signaling pathway
103014337 (RAF1)
09158 Development and regeneration
04360 Axon guidance
103014337 (RAF1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
103014337 (RAF1)
05206 MicroRNAs in cancer
103014337 (RAF1)
05205 Proteoglycans in cancer
103014337 (RAF1)
05230 Central carbon metabolism in cancer
103014337 (RAF1)
05231 Choline metabolism in cancer
103014337 (RAF1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
103014337 (RAF1)
09162 Cancer: specific types
05210 Colorectal cancer
103014337 (RAF1)
05212 Pancreatic cancer
103014337 (RAF1)
05225 Hepatocellular carcinoma
103014337 (RAF1)
05226 Gastric cancer
103014337 (RAF1)
05214 Glioma
103014337 (RAF1)
05221 Acute myeloid leukemia
103014337 (RAF1)
05220 Chronic myeloid leukemia
103014337 (RAF1)
05218 Melanoma
103014337 (RAF1)
05211 Renal cell carcinoma
103014337 (RAF1)
05219 Bladder cancer
103014337 (RAF1)
05215 Prostate cancer
103014337 (RAF1)
05213 Endometrial cancer
103014337 (RAF1)
05224 Breast cancer
103014337 (RAF1)
05223 Non-small cell lung cancer
103014337 (RAF1)
09164 Neurodegenerative disease
05010 Alzheimer disease
103014337 (RAF1)
05022 Pathways of neurodegeneration - multiple diseases
103014337 (RAF1)
09165 Substance dependence
05034 Alcoholism
103014337 (RAF1)
09171 Infectious disease: bacterial
05132 Salmonella infection
103014337 (RAF1)
05152 Tuberculosis
103014337 (RAF1)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
103014337 (RAF1)
05161 Hepatitis B
103014337 (RAF1)
05160 Hepatitis C
103014337 (RAF1)
05164 Influenza A
103014337 (RAF1)
05163 Human cytomegalovirus infection
103014337 (RAF1)
05167 Kaposi sarcoma-associated herpesvirus infection
103014337 (RAF1)
05165 Human papillomavirus infection
103014337 (RAF1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
103014337 (RAF1)
01522 Endocrine resistance
103014337 (RAF1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
bacu01001
]
103014337 (RAF1)
Enzymes [BR:
bacu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
103014337 (RAF1)
Protein kinases [BR:
bacu01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
103014337 (RAF1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
RBD
C1_1
Kinase-like
zf-RING-like
Pkinase_fungal
C1_2
Motif
Other DBs
NCBI-GeneID:
103014337
NCBI-ProteinID:
XP_007192656
UniProt:
A0A384AYZ0
LinkDB
All DBs
Position
Un
AA seq
668 aa
AA seq
DB search
MEHIQGAWKTISNGFGFKDAVFDGPSCISPTIVQQFGYQRRASDDGKLTDPSKTSNTIRV
FLPNKQRTVVNVRNGMSLHDCLMKALKVRGLQPECCAVFRLLHEHKGKKARLDWNTDAAS
LIGEELQVDFLDHVPLTTHNFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKV
PTMCVDWSNIRQLLLFPNSIVGDSGIPVMPSLTMRRMRESVSRMPVSSQHRYSTPHAFTF
NTSSPSSEGSLSQRQRSTSTPNVHMVSTNLPVDSRMIENNSLNASPRAWSRRFCLRGRDA
IRSHSESASPSALSSSPNNLSPTGWSQPKTPVPAQRERAPGSSTQEKNKIRPRGQRDSSY
YWEIEASEVMLSTRIGSGSFGTVYKGKWHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKT
RHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLH
AKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSILWMAPEVIRMQ
DNNPFSFQSDVYSYGIVLYELMTGELPYSHISNRDQIIFMVGRGYASPDLSKLYKNCPKA
MKRLVADCVKKVKEERPLFPQILSSIELLQHSLPKINRSASEPSLHRAAHTEDINACTLT
TSPRLPVF
NT seq
2007 nt
NT seq
+upstream
nt +downstream
nt
atggagcacatacagggggcctggaagacgatcagcaatggttttggattcaaagatgcg
gtgtttgatggccccagctgcatctcccctacaatagttcagcagtttggctatcagcgt
cgggcatcagatgatggcaaacttacggacccttctaagacaagcaacactatccgtgtt
tttttgccaaacaagcaaagaacagtggtcaatgtgcggaatggaatgagcttgcatgac
tgccttatgaaagctctcaaggtgaggggcctgcaaccagagtgctgtgcagttttcaga
cttctccacgaacacaagggtaaaaaagcacgtttagattggaatactgatgctgcctca
ttgattggagaggaacttcaagtagatttcttggatcatgttccgctcacaacacacaac
tttgctcggaagaccttcctgaagcttgccttctgtgacatctgtcagaagttcctgcta
aatgggtttagatgtcagacttgtggctacaagtttcacgagcattgtagcaccaaagta
cctactatgtgtgtggactggagtaatatcagacaactcttgctgttcccaaattccatt
gttggtgatagtgggatcccagtaatgccttctttgacaatgcgtcggatgcgagagtct
gtttcccggatgcctgttagttcccagcacagatactccacaccccacgctttcacattc
aacacctccagcccctcctctgaaggttccctctcccagaggcagaggtcgacatccaca
cctaatgtccacatggtcagcaccaacttgcccgtggacagcaggatgattgagaataac
agcctgaatgcttctcccagggcgtggtccagacgattttgtttgaggggaagagatgca
attcgaagtcacagtgaatcagcctcaccttcagccttgtccagcagtcccaacaatctg
agcccaacaggctggtcacagcccaaaacccctgtgccggcacagagagagcgggcaccg
ggatccagcacccaggagaaaaacaaaattaggcctcgtggacagagagattcaagctat
tactgggaaatagaagccagtgaagtgatgctctccactcggattgggtcaggctccttt
ggaactgtttataagggcaagtggcatggagacgttgcagtaaagattctaaaggttgtt
gatcccacaccagagcagttccaggcctttaggaatgaagtggctgtccttcgcaaaacc
cggcacgtgaacatcctgctcttcatggggtacatgacgaaggacaacctggcaattgtg
acccagtggtgcgagggcagcagcctctataaacacctgcacgtccaggagaccaagttc
cagatgttccagttgattgacattgcccggcagacggctcagggaatggactatttgcat
gcaaagaacatcatccacagagacatgaaatccaacaatatatttctccatgaaggcctg
acggtgaaaattggagattttggtttggcaacagtgaagtcgcgctggagtggttctcag
caggttgaacaacccaccggctccatcttgtggatggccccagaggtgattcgaatgcag
gacaataacccgttcagcttccagtccgacgtctactcgtatggcatcgtgctgtacgag
ctcatgacgggggagctgccctactcccacatcagcaaccgcgatcagatcatcttcatg
gtgggccgagggtacgcctccccagaccttagtaagctgtacaagaactgccccaaagca
atgaagaggctggtagccgactgtgtgaagaaagttaaggaagagaggcctctttttccc
cagatcctgtcttccattgagctgctccaacactctctaccgaaaatcaaccggagcgct
tctgagccatccctgcaccgggcggcccataccgaggacatcaatgcctgcacgctgacc
acatcccctagattgcctgtcttctag
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