Balaenoptera acutorostrata scammoni (minke whale): 103015537
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Entry
103015537 CDS
T03086
Gene name
IGF1R
Definition
(RefSeq) insulin like growth factor 1 receptor
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
bacu
Balaenoptera acutorostrata scammoni (minke whale)
Pathway
bacu01521
EGFR tyrosine kinase inhibitor resistance
bacu01522
Endocrine resistance
bacu04010
MAPK signaling pathway
bacu04014
Ras signaling pathway
bacu04015
Rap1 signaling pathway
bacu04066
HIF-1 signaling pathway
bacu04068
FoxO signaling pathway
bacu04114
Oocyte meiosis
bacu04140
Autophagy - animal
bacu04144
Endocytosis
bacu04150
mTOR signaling pathway
bacu04151
PI3K-Akt signaling pathway
bacu04152
AMPK signaling pathway
bacu04211
Longevity regulating pathway
bacu04213
Longevity regulating pathway - multiple species
bacu04510
Focal adhesion
bacu04520
Adherens junction
bacu04550
Signaling pathways regulating pluripotency of stem cells
bacu04730
Long-term depression
bacu04913
Ovarian steroidogenesis
bacu04914
Progesterone-mediated oocyte maturation
bacu05200
Pathways in cancer
bacu05202
Transcriptional misregulation in cancer
bacu05205
Proteoglycans in cancer
bacu05214
Glioma
bacu05215
Prostate cancer
bacu05218
Melanoma
bacu05224
Breast cancer
bacu05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
bacu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
103015537 (IGF1R)
04014 Ras signaling pathway
103015537 (IGF1R)
04015 Rap1 signaling pathway
103015537 (IGF1R)
04066 HIF-1 signaling pathway
103015537 (IGF1R)
04068 FoxO signaling pathway
103015537 (IGF1R)
04151 PI3K-Akt signaling pathway
103015537 (IGF1R)
04152 AMPK signaling pathway
103015537 (IGF1R)
04150 mTOR signaling pathway
103015537 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
103015537 (IGF1R)
04140 Autophagy - animal
103015537 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
103015537 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
103015537 (IGF1R)
04520 Adherens junction
103015537 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
103015537 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
103015537 (IGF1R)
04914 Progesterone-mediated oocyte maturation
103015537 (IGF1R)
09156 Nervous system
04730 Long-term depression
103015537 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
103015537 (IGF1R)
04213 Longevity regulating pathway - multiple species
103015537 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
103015537 (IGF1R)
05202 Transcriptional misregulation in cancer
103015537 (IGF1R)
05205 Proteoglycans in cancer
103015537 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
103015537 (IGF1R)
05214 Glioma
103015537 (IGF1R)
05218 Melanoma
103015537 (IGF1R)
05215 Prostate cancer
103015537 (IGF1R)
05224 Breast cancer
103015537 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
103015537 (IGF1R)
01522 Endocrine resistance
103015537 (IGF1R)
Enzymes [BR:
bacu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
103015537 (IGF1R)
Protein kinases [BR:
bacu01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
103015537 (IGF1R)
CD molecules [BR:
bacu04090
]
Proteins
103015537 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Pkinase
Furin-like
fn3
Kinase-like
Insulin_TMD
DUF4476
Motif
Other DBs
NCBI-GeneID:
103015537
NCBI-ProteinID:
XP_007191236
LinkDB
All DBs
Position
Un
AA seq
1345 aa
AA seq
DB search
MVSFEAGCRICGPGIDIRNDYQQLKRLENCTVIEGYLHILLISKAEDYRSYRFPKLTVIT
EYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIR
IEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGDLCPGTMEEKPLCEKTTINNEYN
YRCWTTNRCQKMCPSACGKRACTENHECCHPECLGSCSAPDNDTACVACRHYYYAGVCVP
SCPPNTYRFEGWRCVDRDFCANIPNAESSDSEGFVIHDGECMQECPSGFIRNGSQSMYCI
PCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNLLINIRRGNNIASELENFMGLIE
VVTGYVKIRHSHALVSLSFLKNLRQILGEEQLEGNYSFYVLDNQNLQQLWDWDHRNLTIK
AGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTRNNGERASCESDVLHFTSTTTWK
NRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDGQDACGSNSWNMVDVDLPPNKDV
EPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSEILYIRTNASVPSIPLDVLSASN
SSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDSYLYRHNYCSKDKIPIRKYADGTIDVEE
VTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRKVFENFLHNAIFVPRPERKRREV
MQVANTTMSSRSRNTTVVDTYNITDPEELETEYPFFESRVDNKERTVISNLRPFTLYRID
IHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTWEPRPENSIFLKWPEPENPNGLI
LMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGNYTARIQATSLSGNGSWTDPVFF
YVQAKTTYENFIHLIIALPIAVLLIVGGLVIMLYVFHRKRNNSRLGNGVLYASVNPEYFS
AADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMR
ERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEMENNP
VLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYE
TDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWEIATLAEQPYQGLSNEQVL
RFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKDEMEPGFREVSFYYS
EENKPPEPEELDLEPENMESVPLDPSASSSSLPLPDRHSGHKAENGPGPGVLVLRASFDE
RQPYAHMNGGRKKERALPLPQSSTC
NT seq
4038 nt
NT seq
+upstream
nt +downstream
nt
atggtgtcctttgaggctggctgcaggatctgtgggccaggcatcgacatccgcaacgac
taccagcagctgaagcgactggagaactgcacggtgatcgagggctacctccatatcctg
ctcatttccaaggctgaggactaccgcagctaccgcttccccaagctcacggtcatcact
gagtacctgctgctgttccgcgtggctggcctcgagagcctcggcgacctcttccccaac
ctcacagtcatccgtggctggaagctcttctacaactacgccctggtcatcttcgagatg
accaacctcaaggatatcgggctctacaacctgcgaaacattacccgtggggccatccgg
atcgagaagaatgctgacctctgctacctctccacggtggactggtccctaatcctggat
gccgtgtccaataactacattgtggggaataagcccccaaaggagtgtggggacctgtgc
ccggggacgatggaggagaagccgctgtgcgagaagacgaccatcaacaacgagtacaac
taccgctgctggaccacgaaccgctgtcagaaaatgtgcccgagcgcgtgcgggaagcgg
gcgtgcacggagaaccacgagtgctgccaccccgagtgcctgggcagctgcagcgctccc
gacaacgacacggcctgcgtggcctgccgccactactactatgccggtgtctgtgtgccc
agctgcccgcccaacacctaccgcttcgagggctggcgttgcgtggaccgtgacttctgc
gccaacatccccaacgctgagagcagcgattccgagggcttcgtgatccacgatggcgag
tgcatgcaggagtgcccgtcgggcttcatccgcaacggcagccagagcatgtactgcatc
ccttgcgaaggcccttgtcccaaagtgtgtgaggaagaaaagaagacaaagaccattgat
tctgtcacttctgctcagatgctccaaggatgcaccatcttcaagggcaatctactcatt
aatatccgacgcggcaacaacatcgcttcagaactggagaacttcatgggactcatcgag
gtcgtgacgggctacgtgaagatccgccactcccatgccttggtctccttgtccttcctg
aagaaccttcgccagatcctaggagaggagcagctagaggggaattactccttctacgtc
ctcgacaaccagaacttgcagcagctgtgggactgggaccaccgcaacctgaccatcaaa
gctgggaaaatgtactttgctttcaatcccaaattgtgtgtctccgagatttaccgcatg
gaggaagtgacagggactaaaggacgccagagcaaaggggacataaacaccaggaacaac
ggagagagagcctcctgtgaaagtgacgtcctgcacttcacctccaccaccacgtggaag
aaccgcatcatcatcacctggcaccggtaccggccccctgactacagggacctcatcagc
ttcaccgtctactacaaggaagcaccctttaaaaacgtcacagagtatgacgggcaggat
gcctgcggctccaacagctggaacatggtagatgtggacctcccacccaacaaggacgtg
gagcccggcattttactgcatggactgaagccctggacacagtatgccgtttacgtcaag
gctgtgaccctcaccatggtggagaatgaccacatccgtggagccaagagcgagatcttg
tacattcgcaccaatgcttcagttccttccatccccctggatgtactctcagcatcaaac
tcctcttctcagctgatcgtgaagtggaaccctccttccctgcccaacggcaacctgagc
tactacatcgtgaggtggcagcgccagccccaggacagctacctttaccggcacaattac
tgctccaaagacaaaatccccatcaggaagtacgccgacggcaccatcgacgttgaggag
gtgacggagaatcctaagaccgaagtgtgtggtggggagaaagggccgtgctgcgcttgc
cccaagaccgaagccgagaagcaggccgagaaggaggaggccgagtaccgcaaggtcttc
gagaatttcctgcacaacgccatcttcgtgcccagacctgaacggaagcggagggaggtc
atgcaggtcgccaacaccaccatgtccagccggagcaggaacaccacggtggtggacacc
tacaacatcacagacccggaagagctcgagaccgagtaccctttctttgagagcagagtg
gataacaaggagagaactgtcatctccaacctccggccttttactctgtaccgaatcgat
atccacagctgtaaccacgaagctgagaagctcggctgcagcgcctccaactttgtcttt
gcaagaaccatgcctgcagaaggagcagatgacattcctgggccagtgacctgggagcca
aggcctgagaactccatctttttaaaatggccagaacctgagaatcccaatggattgatt
ttaatgtatgaaataaaatacggatcacaagtcgaggatcagcgggaatgtgtgtccaga
caggagtacaggaagtatggaggggccaagctaaaccggctgaacccggggaactacacg
gcccggatccaggccacctctctctctgggaacgggtcgtggactgatcctgtgttcttc
tatgtccaggccaaaacaacgtatgaaaacttcatccatctgatcatcgctctgcccatt
gctgttctgctgatagtaggagggttggttataatgctgtacgtcttccatagaaaaaga
aataacagcaggctggggaacggagtgctgtatgcctctgtgaacccggagtacttcagt
gcagccgatgtgtacgtgcctgacgagtgggaggtcgcccgggagaagatcaccatgagc
cgggagctggggcagggctccttcgggatggtttacgaaggtgtcgccaagggcgtggtc
aaggatgagcctgagaccagggtggccattaagacggtgaacgaggccgccagcatgcgc
gagaggattgagtttctcaacgaggcctcggtgatgaaggagttcaactgtcaccacgtg
gtgcgcttgctgggtgtggtgtcccagggccagccgacgctggtcatcatggaactgatg
acccggggggacctcaaaagttatctccggtctctgaggccagaaatggagaataatcca
gtcctagcacctcccagcctaagcaaaatgatccagatggctggagagattgcagatggc
atggcatacctcaacgccaataagtttgtccacagagacctcgctgcccggaactgcatg
gtggccgaagatttcacagtcaaaatcggagattttgggatgacgagagacatctatgag
accgactattaccggaagggagggaaggggctgctgcctgtgcgctggatgtcccccgag
tccctcaaggatggagtcttcaccacgcactctgacgtctggtccttcggggtcgtcctc
tgggagatcgccacgctggccgagcagccataccagggcctgtccaatgagcaagtcctt
cgcttcgtcatggagggcggccttctggacaagccggacaactgtcctgacatgctgttt
gaactgatgcgcatgtgctggcagtacaaccccaagatgaggccttccttcctggagatc
atcagcagcatcaaggacgagatggagcccggcttccgggaggtctccttctactacagc
gaggagaacaagccgcctgagccagaggagctggacctagagccggagaacatggagagt
gtccccctggacccctcggcctcctcgtcctccctgccgctgcccgacagacactcagga
cacaaggccgagaacggtccgggccctggcgtgctggtccttcgagccagcttcgacgag
agacagccttatgcgcacatgaatgggggccgcaagaaggagcgggccttgcctctgccc
cagtcctcgacctgctga
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integrated database retrieval system
