Bubalus bubalis (water buffalo): 102404660
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Entry
102404660 CDS
T05912
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1 isoform X1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
bbub
Bubalus bubalis (water buffalo)
Pathway
bbub04140
Autophagy - animal
bbub04141
Protein processing in endoplasmic reticulum
bbub04210
Apoptosis
bbub04932
Non-alcoholic fatty liver disease
bbub05010
Alzheimer disease
bbub05012
Parkinson disease
bbub05014
Amyotrophic lateral sclerosis
bbub05016
Huntington disease
bbub05017
Spinocerebellar ataxia
bbub05022
Pathways of neurodegeneration - multiple diseases
bbub05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
bbub00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
102404660 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
102404660 (ERN1)
09143 Cell growth and death
04210 Apoptosis
102404660 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
102404660 (ERN1)
05012 Parkinson disease
102404660 (ERN1)
05014 Amyotrophic lateral sclerosis
102404660 (ERN1)
05016 Huntington disease
102404660 (ERN1)
05017 Spinocerebellar ataxia
102404660 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
102404660 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
102404660 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
102404660 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
bbub01001
]
102404660 (ERN1)
Enzymes [BR:
bbub01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
102404660 (ERN1)
Protein kinases [BR:
bbub01001
]
Serine/threonine kinases: Other
IRE family
102404660 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
PQQ_2
PQQ
Pkinase_fungal
Kdo
APH
PQQ_3
Band_3_cyto
Motif
Other DBs
NCBI-GeneID:
102404660
NCBI-ProteinID:
XP_025135616
EnsemblRapid:
ENSBBUG00015007231
LinkDB
All DBs
Position
3:14721224..14804228
Genome browser
AA seq
974 aa
AA seq
DB search
MLVRLLLLLLALLLPGPGGFGSPSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKEDP
VLQVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGILYMGK
KQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATYF
DYAAALPEDDGDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYIWQREGLRKV
MHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSMV
HEGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFNPGLKGKSKLNYLRNYWL
LIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEEAIDLVDQTSENAPTTVSP
DVEEKFDHAPAKPEAPVDSMLKDMATIILSTFLLIGWVAFIITYPLSIHQQRQLQHQQFQ
KELEKIQLLQQQQLPFHPPGDAAQDAELQDSSGQYSESSATSSPNTSPRASNHSLHSTGS
TSKAVTSPFLEQDDEDEETSMVIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRIL
PECFSFADREVQLLRESDEHPNVIRYFCTERDRQFQYIAIELCAATLQEYVEQKDFAHLG
LEPITLLQQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGRIKAMISDFGLCKKLAVGR
HSFSRRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQ
ANILLGAYSLDCLHPEKHEDVIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQLQFF
QDVSDRIEKEALDGPIVKQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGSSVRDLLR
AMRNKKHHYRELPEEVQETLGALPDDFVRYFTSRFPHLLLHTYRAMELCRHERPFQPYYH
EPPEPQPPVTADAL
NT seq
2925 nt
NT seq
+upstream
nt +downstream
nt
atgcttgtccgattgctgctgctgctgctggcattgctgttgcccggccccgggggtttt
gggagccccagcactgtgacacttcctgaaaccttgctgtttgtgtcaacactggatggg
agtctgcatgccgtcagcaagaggacaggctccatcaaatggactttaaaagaagatcca
gtcctgcaggttccaacacacgtggaagagcctgccttcctcccagatcctaatgatggc
agcctgtacacgcttgggggcaagaacaacgaaggcctgacgaaacttccctttacgatc
cctgagttggtgcaggcatctccgtgccgaagttcagatggcattctctacatgggtaaa
aagcaggacatttggtacgttatcgacctcctgactggggagaagcagcagaccctgtca
tcagcctttgcagacagcctctgcccatcaacctctcttctgtatctggggcgaacagag
tacaccattaccatgtacgacaccaagacccgcgagctgcgctggaacgccacctacttt
gactacgcggccgcgctgcccgaggacgatggggactacaagatgtcccactttgtgtcc
aatggcgatgggctggtggtgacggtggacagcgagtctggggatgtcctgtggatccaa
aactacgcttcccccgtggtggccttttacatctggcagcgcgagggcctgcggaaggtg
atgcacatcaatgtcgccgtggagaccctgcgctacctgaccttcatgtcgggggaggtg
gggcgcatcaccaagtggaagtacccgttccccaaggagacggaggccaagagcaagctg
acgcccaccctgtatgtggggaaatactccaccagcctctatgcttccccctcgatggtg
cacgagggcgtcgccgttgtgccccggggcagcacccttcctttgctggaaggcccccag
accgacggtgtcaccatcggggacaaaggggagtgtgtgatcacgcccagcacggacctg
aagttcaaccccggactcaaaggcaagagcaagctcaactacctgcggaactactggctg
ctcatcggacaccatgaaacccccctgtctgcatccaccaaaatgctggagcgcttcccc
aacaacctgcccaaacaccgggagaacgtgattcccgccgactcggagaagaagagcttt
gaggaggccattgacctggttgaccagacttcagaaaacgcacctaccacggtttctccg
gacgtggaagagaagttcgatcatgcccctgccaagcccgaggcccctgtggactccatg
ctcaaggacatggccaccatcatcctgagcaccttcctgctcatcggctgggtggctttc
atcatcacctaccccctgagcatccaccagcagcggcagctccagcaccagcagttccag
aaggaactggagaagatccagctcctgcagcagcagcagctgcccttccacccgcccggg
gatgcggcacaggacgccgagctccaggactcatccggccagtactcggagagctcggcc
accagcagccccaacacatccccccgagcctccaaccactcgctccactccaccggctcc
acctccaaggctgtcaccagccccttcctggagcaggacgatgaggatgaggagaccagc
atggtgatagttgggaaaatctccttctgtccaaaggatgtcctgggtcatggagctgag
ggcacaatcgtgtaccggggcatgtttgacaaccgtgacgtggcagtcaagaggatcctg
cccgagtgtttcagtttcgcggaccgtgaggtccagctgctgcgagagtcggacgaacac
ccgaatgtgatccgctacttctgcactgagagggaccggcagttccagtacatcgccatc
gagctgtgcgcggccacgctgcaggagtacgtggaacagaaggatttcgcccacctcggc
ctggagcccattaccctgctgcagcagaccacctcgggcctggcccacctgcactccctc
aacatcgttcacagagacctgaagccccacaacatcctcctctccatgcccaacgcgcac
ggcagaatcaaggccatgatctccgactttggcctctgcaagaagctggctgtgggcagg
cacagcttcagccgccgctcgggggtgccgggcaccgaaggttggatcgccccagagatg
ctgagcgaagactgcaaggagaaccccacctacacggtggacatcttctccgcgggctgc
gtcttctactacgtgatatctgagggcagccacccctttggcaagtccctgcaacgccag
gccaacatcctcctgggtgcctacagccttgactgcctgcacccagagaagcatgaggac
gtcattgcccgggagttaatagagaagatgatcgccatggacccccagaagcgcccgtca
gcgaagcatgtgctgaaacaccctttcttctggagcctggaaaagcagctccagttcttc
caggacgtgagtgaccggatagagaaggaggccctggacggcccgatagtgaagcagctg
gagcgtggcgggcgggccgtggtgaagatggactggcgggagaacatcaccgttcccctg
cagacagatctgcggaaattcagaacctataaaggcagttcggtccgagatctcctccga
gccatgaggaataagaagcaccactaccgggagctgcccgaggaggtgcaggagacgctg
ggcgccctccctgacgacttcgtgcgctactttacctcccgcttcccccacctcctcttg
cacacctaccgcgccatggagctgtgccgccacgagaggcccttccagccctactaccac
gagccccccgagccccagccccctgtgactgcagacgccctctga
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