Bos indicus (zebu cattle): 109555842 Help Entry 109555842         CDS       T04792                                  Gene name ADCY5 Definition (RefSeq) adenylate cyclase type 5   KO K08045   adenylate cyclase 5 [EC:4.6.1.1] Organism biu  Bos indicus (zebu cattle) Pathway biu00230   Purine metabolism biu01100   Metabolic pathways biu01522   Endocrine resistance biu04015   Rap1 signaling pathway biu04022   cGMP-PKG signaling pathway biu04024   cAMP signaling pathway biu04062   Chemokine signaling pathway biu04072   Phospholipase D signaling pathway biu04114   Oocyte meiosis biu04211   Longevity regulating pathway biu04213   Longevity regulating pathway - multiple species biu04261   Adrenergic signaling in cardiomyocytes biu04270   Vascular smooth muscle contraction biu04371   Apelin signaling pathway biu04540   Gap junction biu04611   Platelet activation biu04713   Circadian entrainment biu04714   Thermogenesis biu04723   Retrograde endocannabinoid signaling biu04724   Glutamatergic synapse biu04725   Cholinergic synapse biu04726   Serotonergic synapse biu04727   GABAergic synapse biu04728   Dopaminergic synapse biu04750   Inflammatory mediator regulation of TRP channels biu04911   Insulin secretion biu04912   GnRH signaling pathway biu04913   Ovarian steroidogenesis biu04914   Progesterone-mediated oocyte maturation biu04915   Estrogen signaling pathway biu04916   Melanogenesis biu04918   Thyroid hormone synthesis biu04921   Oxytocin signaling pathway biu04923   Regulation of lipolysis in adipocytes biu04924   Renin secretion biu04925   Aldosterone synthesis and secretion biu04926   Relaxin signaling pathway biu04927   Cortisol synthesis and secretion biu04928   Parathyroid hormone synthesis, secretion and action biu04934   Cushing syndrome biu04935   Growth hormone synthesis, secretion and action biu04970   Salivary secretion biu04971   Gastric acid secretion biu04972   Pancreatic secretion biu04976   Bile secretion biu05012   Parkinson disease biu05030   Cocaine addiction biu05031   Amphetamine addiction biu05032   Morphine addiction biu05034   Alcoholism biu05163   Human cytomegalovirus infection biu05166   Human T-cell leukemia virus 1 infection biu05200   Pathways in cancer biu05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:biu00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     109555842 (ADCY5)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     109555842 (ADCY5)    04371 Apelin signaling pathway     109555842 (ADCY5)    04072 Phospholipase D signaling pathway     109555842 (ADCY5)    04024 cAMP signaling pathway     109555842 (ADCY5)    04022 cGMP-PKG signaling pathway     109555842 (ADCY5)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     109555842 (ADCY5)   09144 Cellular community - eukaryotes    04540 Gap junction     109555842 (ADCY5)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     109555842 (ADCY5)    04062 Chemokine signaling pathway     109555842 (ADCY5)   09152 Endocrine system    04911 Insulin secretion     109555842 (ADCY5)    04923 Regulation of lipolysis in adipocytes     109555842 (ADCY5)    04912 GnRH signaling pathway     109555842 (ADCY5)    04913 Ovarian steroidogenesis     109555842 (ADCY5)    04915 Estrogen signaling pathway     109555842 (ADCY5)    04914 Progesterone-mediated oocyte maturation     109555842 (ADCY5)    04921 Oxytocin signaling pathway     109555842 (ADCY5)    04926 Relaxin signaling pathway     109555842 (ADCY5)    04935 Growth hormone synthesis, secretion and action     109555842 (ADCY5)    04918 Thyroid hormone synthesis     109555842 (ADCY5)    04928 Parathyroid hormone synthesis, secretion and action     109555842 (ADCY5)    04916 Melanogenesis     109555842 (ADCY5)    04924 Renin secretion     109555842 (ADCY5)    04925 Aldosterone synthesis and secretion     109555842 (ADCY5)    04927 Cortisol synthesis and secretion     109555842 (ADCY5)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     109555842 (ADCY5)    04270 Vascular smooth muscle contraction     109555842 (ADCY5)   09154 Digestive system    04970 Salivary secretion     109555842 (ADCY5)    04971 Gastric acid secretion     109555842 (ADCY5)    04972 Pancreatic secretion     109555842 (ADCY5)    04976 Bile secretion     109555842 (ADCY5)   09156 Nervous system    04724 Glutamatergic synapse     109555842 (ADCY5)    04727 GABAergic synapse     109555842 (ADCY5)    04725 Cholinergic synapse     109555842 (ADCY5)    04728 Dopaminergic synapse     109555842 (ADCY5)    04726 Serotonergic synapse     109555842 (ADCY5)    04723 Retrograde endocannabinoid signaling     109555842 (ADCY5)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     109555842 (ADCY5)   09149 Aging    04211 Longevity regulating pathway     109555842 (ADCY5)    04213 Longevity regulating pathway - multiple species     109555842 (ADCY5)   09159 Environmental adaptation    04713 Circadian entrainment     109555842 (ADCY5)    04714 Thermogenesis     109555842 (ADCY5)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     109555842 (ADCY5)   09164 Neurodegenerative disease    05012 Parkinson disease     109555842 (ADCY5)   09165 Substance dependence    05030 Cocaine addiction     109555842 (ADCY5)    05031 Amphetamine addiction     109555842 (ADCY5)    05032 Morphine addiction     109555842 (ADCY5)    05034 Alcoholism     109555842 (ADCY5)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     109555842 (ADCY5)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     109555842 (ADCY5)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     109555842 (ADCY5)    05163 Human cytomegalovirus infection     109555842 (ADCY5)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     109555842 (ADCY5) Enzymes [BR:biu01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      109555842 (ADCY5) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  AC_N Guanylate_cyc DUF1053 HNOBA TBK1_ULD PEN-2 Motif Other DBs NCBI-GeneID:  109555842 NCBI-ProteinID:  XP_019812241 UniProt:  A0A6P5B5X5 LinkDB All DBs Position 1 AA seq 1259 aa AA seqDB search MSSSKSVSPPGYAAQTAAAPASRGGPEHRSAWGEADSRANGYPQAPGGSARGSTKRPGGA VTPQQQQRLASRWRSDDEDDPPLSGDDPLAGGFGFSFRSKSAWQERGGDDCGRGSRRQRR GAAGGGSTRAPPAGSGGGSVXXXXAAGGTEVRPRSVELGLEERRGKGRAADDLEAGAVEE DEGSGDGGSSAGSGAGPGAVLSLGACCLALLQIFRSKKFPSDKLERLYQRYFFRLNQSSL TMLMAVLVLVCLVMLAFHAARPPLQLPYLAVLAAAVGVILVMAVLCNRAAFHQDHMGLAC YALIAVVLAVQVVGLLLPQPRSASEGIWWTVFFIYTIYTLLPVRMRAAVLSGVLLSALHL AIALRTNAQDQFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQAFQETRECIQARLHSQ RENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEGFTSLA SQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEMGM DMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGKAG RIHITKATLNYLNGDYEVEPGCGGERNAYLKEHSIETFLILRCTQKRKEEKAMIAKMNRQ RTNSIGHNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDPKDKNAQESSNPEDEVDEFLGR AIDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVACASLVFLFICFVQITI VPHSVFMLSFYLTCFLLLTLVVFVSVIYSCVKLFPAPLQTLSRKIVRSKMNSTLVGVFTI TLVFLSAFVNMFTCNSKDLFGCLGDEHNISASQVNACHVVESAVNYSLGDEQGFCGSSWP NCNFPEYFTYSVLLSLLACSVFLQISCIGKLVLMLAIELIYVLVVEVPGVTLFDNADLLV TANAIDFNNNGTSQCPEHPTKVALKVVTPIIISVFVLALYLHAQQVESTARLDFLWKLQA TEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSE FYVELEANNEGVECLRLLNEIIADFDEIISEDRFRQLEKIKTIGSTYMAASGLNDSTYDK VGKTHIKALADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWGNT VNVASRMDSTGVPDRIQVTTDMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGGPPPS NT seq 3780 nt NT seq  +upstreamnt  +downstreamnt atgtccagctccaaaagcgtgagccccccgggctacgcggcgcagacagcggcggcgccg gcgtcccggggaggcccggaacaccgctccgcgtggggagaggccgactcccgcgccaat ggctacccccaagcccccgggggttctgcccgcggctccaccaagagacctgggggggcg gtgaccccgcagcagcaacagcgcctggccagccgctggcgcagcgacgacgaagacgat cctccgctgagtggcgatgaccccctggccgggggcttcggcttcagcttccgttccaag tcggcctggcaggagcgcggcggcgacgactgcggtcgcggcagccggcggcagcggcgg ggcgcggccggcgggggcagcacccgggcgccccctgcgggcagcggcggcggttcggtg nnnnnnnnnnncgcagcgggcgggacggaagtgcgcccccgttcggtggagctaggcctg gaggagcggcgtggcaagggccgcgcggccgacgatctggaggccggcgccgtcgaggaa gacgaagggtccggggatgggggcagctcggcaggctcgggcgcggggcctggcgcggtg ctgtcgctgggcgcctgctgcctggcactgctgcagatattccgctctaagaagttccca tcggacaagctggagcggctgtaccagcgctacttcttccgtctgaaccagagcagcctc acaatgctcatggctgtgctggtgctcgtgtgcctagtcatgttggccttccacgcggca cggcccccgctgcagctgccctacctggccgtcctagcggccgccgtgggtgtgatcctc gttatggccgtgctctgcaaccgtgccgccttccaccaggaccacatgggcctggcctgc tacgcgcttatcgccgtggtgctggccgtccaggtggtgggcctgttgctgccccagccg cgcagtgcctccgagggcatctggtggactgtgtttttcatctatacgatctacacgctc ctgcccgtgcgcatgcgggctgcggtactcagcggggtgctcctgtccgccctccacctg gccatcgccctgcgcaccaacgcccaggatcagttcctgctcaagcagctcgtctccaac gtcctcattttctcctgcaccaacattgtgggtgtgtgcacccactacccggctgaggtc tcgcagaggcaggccttccaggagacccgggagtgcatccaggctcggctccactcacag cgggagaaccagcagcaggagcggctcctgctgtctgtccttccccgtcacgttgccatg gagatgaaagccgacatcaacgccaaacaggaggatatgatgttccataagatttacatc cagaaacatgacaacgtgagcattctgtttgctgacatcgagggtttcaccagcctggca tcccagtgcactgcccaggagctggtcatgaccctcaacgagctcttcgcccgcttcgac aagctggctgcggagaatcactgtttacgtattaagatcctgggagattgttattactgt gtctcagggctgcctgaagccagggctgaccacgcccactgctgcgtggagatgggcatg gacatgatcgaggccatctcgctggtccgggaggtgacaggtgtgaacgtgaacatgcgt gtgggaattcacagcgggagagtgcactgcggtgtcctcggcctcaggaagtggcagttc gatgtctggtctaacgatgtcacactggccaaccacatggaggctggaggcaaggcggga cgcatccacatcaccaaggccactctcaactacttgaatggtgactacgaagtggagcca ggctgtgggggcgagcgcaacgcctacctcaaggagcacagtatcgagacctttctcatc ctgcgctgcacccagaagcggaaagaagagaaggccatgattgccaagatgaaccgtcag agaaccaactccatcgggcacaacccgccccactggggggccgagcgccccttctataac cacctggggggcaaccaggtgtccaaggagatgaagcggatgggctttgaagaccccaag gacaagaatgcccaggaaagttcgaaccctgaggatgaagtggatgaatttctgggccgt gccattgatgccaggagcatcgacaggctgcgatctgaacatgttcgcaagttcctcttg accttcagggagcctgacttagagaagaagtactccaagcaggtggatgaccgattcggt gcctacgtggcctgtgcctcgctcgtcttcctcttcatctgctttgtccagatcaccatt gtgccccactccgtgttcatgttgagtttctacctgacctgtttcctgctgctgaccttg gtggtgtttgtgtccgtgatctattcttgcgtgaagctcttcccagccccgctgcagacg ctctccaggaagatcgtgcggtccaagatgaacagcaccctggtgggggtgttcaccatc accctcgtgttcctgtcggctttcgtcaacatgttcacgtgcaactccaaggacctgttt ggctgcctgggggacgagcacaacatcagtgccagtcaggtcaatgcatgccacgtggtg gagtcggccgtcaactacagtctgggtgacgagcagggcttctgcggcagctcctggccc aactgcaacttccccgagtacttcacctatagcgtgctgctcagcctgctggcctgctcc gtgttcctgcagatcagctgcatcgggaagctggtgctcatgctggccatcgagctcatc tacgtgctcgtcgttgaggtgcccggtgtcacgctctttgacaatgccgacctactggtc acggccaacgccatagacttcaacaacaacgggacctcccagtgccctgagcatccaacc aaggtggcgctgaaggtggtgacgcccatcatcatctccgtcttcgtgctggccctgtac ctgcatgcccagcaggtggagtccactgcccgcctcgacttcctctggaaacttcaggcc acggaggagaaggaggagatggaggagctgcaggcctacaaccggcggctgctgcacaac attctgcccaaggacgtggccgcacacttcctggcccgcgaacggcgcaacgacgagctc tactatcagtcgtgcgagtgcgtggccgtcatgttcgcctccatcgccaacttctctgag ttctacgtggaactagaggccaacaacgagggcgtcgagtgcctgcggctgctcaacgag atcatcgcagactttgacgagatcattagtgaggaccggttcaggcagctggaaaagatc aagaccatcggcagcacctacatggccgcctccggcctcaatgactccacctacgacaag gtgggcaagacccacatcaaagccctggccgacttcgccatgaagttgatggaccaaatg aagtacatcaacgagcactctttcaacaacttccagatgaagatcgggctcaatattggc cccgtggtggcgggtgtgattggagcccgcaagcctcagtacgacatctggggcaatacg gtgaacgtggccagccgcatggacagcaccggtgtgcccgaccgcatccaggtcaccaca gacatgtaccaggtgctggccgccaatacgtaccagctggagtgccggggtgtggtcaag gtcaagggcaaaggcgagatgatgacctacttcctcaacggaggacccccgcccagttag

Bos indicus (zebu cattle): 109557525 Help Entry 109557525         CDS       T04792                                  Gene name ADCY1 Definition (RefSeq) adenylate cyclase type 1   KO K08041   adenylate cyclase 1 [EC:4.6.1.1] Organism biu  Bos indicus (zebu cattle) Pathway biu00230   Purine metabolism biu01100   Metabolic pathways biu01522   Endocrine resistance biu04015   Rap1 signaling pathway biu04020   Calcium signaling pathway biu04022   cGMP-PKG signaling pathway biu04024   cAMP signaling pathway biu04062   Chemokine signaling pathway biu04072   Phospholipase D signaling pathway biu04114   Oocyte meiosis biu04211   Longevity regulating pathway biu04213   Longevity regulating pathway - multiple species biu04261   Adrenergic signaling in cardiomyocytes biu04270   Vascular smooth muscle contraction biu04371   Apelin signaling pathway biu04540   Gap junction biu04611   Platelet activation biu04713   Circadian entrainment biu04714   Thermogenesis biu04720   Long-term potentiation biu04723   Retrograde endocannabinoid signaling biu04724   Glutamatergic synapse biu04725   Cholinergic synapse biu04727   GABAergic synapse biu04750   Inflammatory mediator regulation of TRP channels biu04911   Insulin secretion biu04912   GnRH signaling pathway biu04913   Ovarian steroidogenesis biu04914   Progesterone-mediated oocyte maturation biu04915   Estrogen signaling pathway biu04916   Melanogenesis biu04918   Thyroid hormone synthesis biu04921   Oxytocin signaling pathway biu04923   Regulation of lipolysis in adipocytes biu04925   Aldosterone synthesis and secretion biu04926   Relaxin signaling pathway biu04927   Cortisol synthesis and secretion biu04928   Parathyroid hormone synthesis, secretion and action biu04934   Cushing syndrome biu04935   Growth hormone synthesis, secretion and action biu04970   Salivary secretion biu04971   Gastric acid secretion biu04972   Pancreatic secretion biu04976   Bile secretion biu05032   Morphine addiction biu05142   Chagas disease biu05146   Amoebiasis biu05163   Human cytomegalovirus infection biu05166   Human T-cell leukemia virus 1 infection biu05200   Pathways in cancer biu05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:biu00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     109557525 (ADCY1)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     109557525 (ADCY1)    04371 Apelin signaling pathway     109557525 (ADCY1)    04020 Calcium signaling pathway     109557525 (ADCY1)    04072 Phospholipase D signaling pathway     109557525 (ADCY1)    04024 cAMP signaling pathway     109557525 (ADCY1)    04022 cGMP-PKG signaling pathway     109557525 (ADCY1)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     109557525 (ADCY1)   09144 Cellular community - eukaryotes    04540 Gap junction     109557525 (ADCY1)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     109557525 (ADCY1)    04062 Chemokine signaling pathway     109557525 (ADCY1)   09152 Endocrine system    04911 Insulin secretion     109557525 (ADCY1)    04923 Regulation of lipolysis in adipocytes     109557525 (ADCY1)    04912 GnRH signaling pathway     109557525 (ADCY1)    04913 Ovarian steroidogenesis     109557525 (ADCY1)    04915 Estrogen signaling pathway     109557525 (ADCY1)    04914 Progesterone-mediated oocyte maturation     109557525 (ADCY1)    04921 Oxytocin signaling pathway     109557525 (ADCY1)    04926 Relaxin signaling pathway     109557525 (ADCY1)    04935 Growth hormone synthesis, secretion and action     109557525 (ADCY1)    04918 Thyroid hormone synthesis     109557525 (ADCY1)    04928 Parathyroid hormone synthesis, secretion and action     109557525 (ADCY1)    04916 Melanogenesis     109557525 (ADCY1)    04925 Aldosterone synthesis and secretion     109557525 (ADCY1)    04927 Cortisol synthesis and secretion     109557525 (ADCY1)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     109557525 (ADCY1)    04270 Vascular smooth muscle contraction     109557525 (ADCY1)   09154 Digestive system    04970 Salivary secretion     109557525 (ADCY1)    04971 Gastric acid secretion     109557525 (ADCY1)    04972 Pancreatic secretion     109557525 (ADCY1)    04976 Bile secretion     109557525 (ADCY1)   09156 Nervous system    04724 Glutamatergic synapse     109557525 (ADCY1)    04727 GABAergic synapse     109557525 (ADCY1)    04725 Cholinergic synapse     109557525 (ADCY1)    04720 Long-term potentiation     109557525 (ADCY1)    04723 Retrograde endocannabinoid signaling     109557525 (ADCY1)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     109557525 (ADCY1)   09149 Aging    04211 Longevity regulating pathway     109557525 (ADCY1)    04213 Longevity regulating pathway - multiple species     109557525 (ADCY1)   09159 Environmental adaptation    04713 Circadian entrainment     109557525 (ADCY1)    04714 Thermogenesis     109557525 (ADCY1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     109557525 (ADCY1)   09165 Substance dependence    05032 Morphine addiction     109557525 (ADCY1)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     109557525 (ADCY1)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     109557525 (ADCY1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     109557525 (ADCY1)    05163 Human cytomegalovirus infection     109557525 (ADCY1)   09174 Infectious disease: parasitic    05146 Amoebiasis     109557525 (ADCY1)    05142 Chagas disease     109557525 (ADCY1)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     109557525 (ADCY1) Enzymes [BR:biu01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      109557525 (ADCY1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N DUF1053 HNOBA Motif Other DBs NCBI-GeneID:  109557525 NCBI-ProteinID:  XP_019814464 UniProt:  A0A6P5BQU8 LinkDB All DBs Position 4 AA seq 1128 aa AA seqDB search LAVGGGGGGGAGESVGAERRAGPGGRRGLRACDEEFACPELEALFRGYTLRLEQAATLKA LAXLSLLAGALALAELLGAPGPAPGLAKGSHPVHCVLFLALLVVTNVRSLQVPQLQQVGQ LALLFSLTFALLCCPFALGGPAGAHAGAAAVPATADQGVWQLLLVTFVSYALLPVRSLLA IGFGLVVAASHLLVTATLVPAKRPRLWRTLGANALLFLGVNVYGVFVRILAERAQRKAFL QARNCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQRHDNVSI LFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGLTQPK TDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVT LANVMEAAGLPGKVHITKTTLACLNGDYEVEPGHGHERNSFLKTHNIETFFIVPSHRRKI FPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVMTCEDDDKRRALRTASE KLRNRSSFSTNVVQTTPGTRVNRYIGRLLEARQMELEMADLNFFTLKYKQAERERKYHQL QDEYFTSAVVLALILAALFGLVYLLIIPQSVAVLLLLVFCICFLVACVLYLHITRVQCFP GCLTIQIRTVLCIFIVVLIYSVAQGCVVGCLPWSXCSSPNGSLVVLSSGGRDPVLPVPPC ESAPHALLCGLVGTLPLAIFLRVSSLPKMILLAVLTTSYILVLELSGYTKAMGAGAISGR SFEPIVAILLFSCTLALHARQVDVKLRLDYLWAAQAEEERDDMEKVKLDNKRILFNLLPA HVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIELDGNNMGVECLRLLNEIIAD FDELMDKDFYKDLEKIKTIGSTYMAAVGLAPTAGTKAKKCISSHLSTLADFAIEMFDVLD EINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGRIQVTEE VHRLLRRGSYRFVCRGKVSVKGKGEMLTYFLEGRTDGNGSQTRSLNSERKMYPFGRAGLQ XRLAAGHPPVPPAAGLPVGAGPGALQGSGLAPGPPGQHLPPGASGKEA NT seq 3387 nt NT seq  +upstreamnt  +downstreamnt ctagcagtcggcggcggaggcggaggcggcgcgggcgagtctgttggcgccgagcggcgg gcggggccgggcggccggcgcgggctgcgggcgtgcgatgaggagttcgcgtgccccgag ctggaggcgctgttccgcggctacacgctgcggctggagcaggcggcgacgctgaaggcg ctggccrtgctcagcctgctggcgggcgcgctggccctggccgagctgctgggcgcgccg gggcccgcgcccggcctggctaagggctcgcaccccgtgcactgcgtgctcttcctggcg ctgctcgtggtcaccaacgtccgctcgctgcaggtgccccagctgcagcaggtcggccag ctcgcgctgctcttcagcctcaccttcgctctgctgtgctgtcccttcgcgctcggcggc cccgccggtgcccacgccggggcggcagcggtgccggcgacagccgatcagggagtctgg cagctccttttggtyaccttcgtgtcctatgccctgctgcccgtgcgcagcctgctggcc atcggcttcgggctcgtggtggccgcctcgcacttgctggtcacggctacgttggtcccc gccaagcgcccacgtctctggagaacgctgggtgccaacgctctgctcttcctyggtgtg aacgtgtatggcgtcttcgtgaggatcctggctgagcgcgcccagaggaaggccttcctg caggcccggaactgcattgaggaccggctgaggctggaggaygagaatgagaagcaggag cggctgctcatgagcctcctgcctcggaatgttgccatggagatgaaggaggacttcctg aagccccctgagaggattttccacaagatttacatccagcggcatgacaacgtgagcatc ctctttgcagacatcgtgggcttcacaggcttggcgtcacagtgcacggcccaggagctg gtgaaactcctcaaygagctcttygggaagtttgacgagctggccacagagaaccactgc cgccgcatcaagatcctgggagattgctactactgcgtgtctggcctcactcagcccaag actgaccacgcccactgctgtgtggagatgggcctggacatgatcgacaccatcacgtcc gtggctgaggccactgaggtggacttgaacatgcgtgtggggctgcacaccggcagggtc ctctgcggggtcctgggcctgcgtaagtggcagtatgatgtgtggtccaacgacgtgacc ctggccaacgtcatggaggctgccggcctgcctgggaaggttcacatcacaaagaccacc ctggcgtgcctgaatggtgactatgaggtggagccgggacacggacacgagaggaacagt tttctgaaaactcataacatygagaccttttttattgtgccctcgcatcggcgaaagata tttccagggctgattctctcagacataaaaccggccaagaggatgaagttcaagaccgtg tgctacctgctggtgcagctcatgcactgccggaagatgttcaaggccgagatccctttc tccaacgtcatgacctgtgaggaygacgacaagcggagggcactgagaacagcctcggaa aaactcagaaaccgctcgtctttctctacaaacgttgtccaaaccacccccggcacacgt gtcaacaggtacatcggccgcctcctggaagcccgccagatggagctggagatggcagac ctgaacttcttcaccctgaagtacaagcaagctgagcgagagcgaaagtaccaccagctt caggacgagtatttcaccagcgccgtggttctggctctcattctggccgccttattcggc cttgtctaccttctaataatcccacagagtgtggctgtcctgctcctgctggtgttctgc atctgcttcctggtggcctgtgtcctgtacctacacatcacccgggtccagtgttttcca gggtgcctgaccatccagatccgcaccgtcttgtgcatcttcatcgtggtcttaatctac tctgtggcccaaggctgtgtggtgggctgcctgccttggtcctngtgctccagtcccaac gggtccctggtggtcctgtcttctgggggccgggacccagtgctgcctgtcccgccctgc gagtctgcgccccatgccctgctgtgcggcctcgtgggcaccctcccgctggccatattc ctgcgggtctcctccttgccaaaaatgatcctgctcgccgtgctcaccacctcctacatc ctcgtcctggagctcagcgggtacacgaaggccatgggggccggtgccatctcagggcgc agcttcgagccgatcgtggccatcctgctattctcgtgcacgctggccctgcacgcccgg caggtggatgtcaagctgcggctggactacctctgggcggcccaggcagaggaggagcgg gatgacatggagaaagtgaagctggacaacaagaggattctcttcaacctcctgccagcc cacgttgcccagcacttcctaatgtccaaccctcgcaacatggacctgtattaccagtca tactcgcaggtgggggtcatgtttgcatccatccccaacttcaatgacttctacatcgag ctggatggcaacaacatgggggtggaatgtctacgccttctgaatgagatcatcgctgac tttgatgagctcatggacaaagacttttacaaggacctagagaagatcaagaccattggg agcacgtacatggctgctgtggggctggcgcccactgctgggaccaaggctaagaagtgc atctcctcccacctcagcacgttggcagattttgccatcgagatgtttgatgtcctggat gagatcaactaccagtcttataacgactttgtgctccgtgttggcatcaacgttggcccc gtggtggctggagtgatcggggctcgcaggccgcagtatgacatttgggggaacacggtc aatgtggccagtcggatggacagtaccggcgtccagggcaggatccaggtcacagaggaa gttcaccggctgctgcggcggggttcctaccgcttcgtgtgccgaggcaaagtcagtgtc aagggcaagggtgagatgctgacatacttcctggaaggcaggaccgatggaaatggctcc caaaccaggtccctgaactcagagcggaaaatgtatcctttcggaagagctggcctccag ascagactggctgcgggtcaccccccggtacctcctgcagccggcctcccagttggagct gggccaggggctctgcagggctcggggcttgccccaggccccccaggccaacacctgccc cctggagcctctgggaaggaggcttag

Bos indicus (zebu cattle): 109559159 Help Entry 109559159         CDS       T04792                                  Gene name ADCY6 Definition (RefSeq) adenylate cyclase type 6 isoform X1   KO K08046   adenylate cyclase 6 [EC:4.6.1.1] Organism biu  Bos indicus (zebu cattle) Pathway biu00230   Purine metabolism biu01100   Metabolic pathways biu01522   Endocrine resistance biu04015   Rap1 signaling pathway biu04022   cGMP-PKG signaling pathway biu04024   cAMP signaling pathway biu04062   Chemokine signaling pathway biu04072   Phospholipase D signaling pathway biu04114   Oocyte meiosis biu04211   Longevity regulating pathway biu04213   Longevity regulating pathway - multiple species biu04261   Adrenergic signaling in cardiomyocytes biu04270   Vascular smooth muscle contraction biu04371   Apelin signaling pathway biu04540   Gap junction biu04611   Platelet activation biu04713   Circadian entrainment biu04714   Thermogenesis biu04723   Retrograde endocannabinoid signaling biu04724   Glutamatergic synapse biu04725   Cholinergic synapse biu04727   GABAergic synapse biu04742   Taste transduction biu04750   Inflammatory mediator regulation of TRP channels biu04911   Insulin secretion biu04912   GnRH signaling pathway biu04913   Ovarian steroidogenesis biu04914   Progesterone-mediated oocyte maturation biu04915   Estrogen signaling pathway biu04916   Melanogenesis biu04918   Thyroid hormone synthesis biu04921   Oxytocin signaling pathway biu04923   Regulation of lipolysis in adipocytes biu04924   Renin secretion biu04925   Aldosterone synthesis and secretion biu04926   Relaxin signaling pathway biu04927   Cortisol synthesis and secretion biu04928   Parathyroid hormone synthesis, secretion and action biu04934   Cushing syndrome biu04935   Growth hormone synthesis, secretion and action biu04961   Endocrine and other factor-regulated calcium reabsorption biu04962   Vasopressin-regulated water reabsorption biu04970   Salivary secretion biu04971   Gastric acid secretion biu04972   Pancreatic secretion biu04976   Bile secretion biu05032   Morphine addiction biu05163   Human cytomegalovirus infection biu05166   Human T-cell leukemia virus 1 infection biu05200   Pathways in cancer biu05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:biu00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     109559159 (ADCY6)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     109559159 (ADCY6)    04371 Apelin signaling pathway     109559159 (ADCY6)    04072 Phospholipase D signaling pathway     109559159 (ADCY6)    04024 cAMP signaling pathway     109559159 (ADCY6)    04022 cGMP-PKG signaling pathway     109559159 (ADCY6)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     109559159 (ADCY6)   09144 Cellular community - eukaryotes    04540 Gap junction     109559159 (ADCY6)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     109559159 (ADCY6)    04062 Chemokine signaling pathway     109559159 (ADCY6)   09152 Endocrine system    04911 Insulin secretion     109559159 (ADCY6)    04923 Regulation of lipolysis in adipocytes     109559159 (ADCY6)    04912 GnRH signaling pathway     109559159 (ADCY6)    04913 Ovarian steroidogenesis     109559159 (ADCY6)    04915 Estrogen signaling pathway     109559159 (ADCY6)    04914 Progesterone-mediated oocyte maturation     109559159 (ADCY6)    04921 Oxytocin signaling pathway     109559159 (ADCY6)    04926 Relaxin signaling pathway     109559159 (ADCY6)    04935 Growth hormone synthesis, secretion and action     109559159 (ADCY6)    04918 Thyroid hormone synthesis     109559159 (ADCY6)    04928 Parathyroid hormone synthesis, secretion and action     109559159 (ADCY6)    04916 Melanogenesis     109559159 (ADCY6)    04924 Renin secretion     109559159 (ADCY6)    04925 Aldosterone synthesis and secretion     109559159 (ADCY6)    04927 Cortisol synthesis and secretion     109559159 (ADCY6)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     109559159 (ADCY6)    04270 Vascular smooth muscle contraction     109559159 (ADCY6)   09154 Digestive system    04970 Salivary secretion     109559159 (ADCY6)    04971 Gastric acid secretion     109559159 (ADCY6)    04972 Pancreatic secretion     109559159 (ADCY6)    04976 Bile secretion     109559159 (ADCY6)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     109559159 (ADCY6)    04961 Endocrine and other factor-regulated calcium reabsorption     109559159 (ADCY6)   09156 Nervous system    04724 Glutamatergic synapse     109559159 (ADCY6)    04727 GABAergic synapse     109559159 (ADCY6)    04725 Cholinergic synapse     109559159 (ADCY6)    04723 Retrograde endocannabinoid signaling     109559159 (ADCY6)   09157 Sensory system    04742 Taste transduction     109559159 (ADCY6)    04750 Inflammatory mediator regulation of TRP channels     109559159 (ADCY6)   09149 Aging    04211 Longevity regulating pathway     109559159 (ADCY6)    04213 Longevity regulating pathway - multiple species     109559159 (ADCY6)   09159 Environmental adaptation    04713 Circadian entrainment     109559159 (ADCY6)    04714 Thermogenesis     109559159 (ADCY6)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     109559159 (ADCY6)   09165 Substance dependence    05032 Morphine addiction     109559159 (ADCY6)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     109559159 (ADCY6)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     109559159 (ADCY6)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     109559159 (ADCY6)    05163 Human cytomegalovirus infection     109559159 (ADCY6)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     109559159 (ADCY6) Enzymes [BR:biu01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      109559159 (ADCY6) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  AC_N Guanylate_cyc DUF1053 HNOBA TBK1_ULD Motif Other DBs NCBI-GeneID:  109559159 NCBI-ProteinID:  XP_019816241 UniProt:  A0A6P5BFX5 LinkDB All DBs Position 5 AA seq 1166 aa AA seqDB search MSWFSGLLVPKVDERKTAWGERNGQQRPRRGTRTSGFCTPRYMSCLQGAQPPSPTPATAP RCPWQDEAFIRRGGPGKGPELGLRAVALGFEDPEVAGAVGAAEVAPAVATRSRRACWRQL VQVFQSKQFRSAKLERLYQRYFFQMNQSSLTLLMAALVLLTXVLLAFHAAPARPQPAYVA LLACAATLFVALMVVCNRHSFRQDSMWVVSYVVLGILAAVQVGGALAADPRSPSAGLWCP VFFVYITYTLLPIRMRAAVFSGLGLSTLHLVLAWQLNRGDAFLWKQLGANMLLFLCTNVI GICTHYPAEVSQRQAFQETRGYIQARLHLQHENRQQERLLLSVLPQHVAMEMKEDINTKK EDMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCLR IKILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRVHC GVLGLRKWQFDVWSNDVTLANHMEAGGRAGRIHITRATLQYLNGDYEVEPGRGGERNAYL KEQHIETFLILGASQKRKEEKAMLAKLQRARANSMEGLMPRWVPDRAFSRTKDSKAFRQM GIDDSSKDNRGAQDALNPEDEVDEFLGRAIDARSIDQLRKDHVRRFLLTFQREDLEKKYS RKVDPRFGAYVACALLVFCFICFIQLVVFPRSALMLGIHASIFLLLLVTVLTCAVYSCGS LFPEALQRVSRSIVRSRAHSTAVGIFSVLLVFTSAVASMFTCNHTPLRTCAARMLNLTPA DITACHLQQLNYSLGLDAPLCEGTAPTCSFPEYFIGNVLLSLLASSVFLHISSIGKLAMI FVLGLVYLVLLLLGPPATIFDNYDLLLGVHGLASSNETFDGLDCPAAGRVALKYMTPVIL LVFALALYLHAQQVESTARLDFLWKLQATGEKEEMEELQAYNRRLLHNILPKDVAAHFLA RERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEIISEE RFRQLEKIKTIGSTYMAASGLNASTYDQVGRSHITALADYAMRLMEQMKHINEHSFNNFQ MKIGLNMGPVVAGVIGARKPQYDIWGNTVNVSSRMDSTGVPDRIQVTTDLYQVLAAKGYQ LECRGVVKVKGKGEMTTYFLNGGPRS NT seq 3501 nt NT seq  +upstreamnt  +downstreamnt atgtcgtggtttagcggcctcttggtccccaaggtggatgaacggaaaacagcctggggg gagcgcaatgggcagcagcggccgcgccgtgggacccgcaccagtggcttctgcacgccc cgctacatgagctgcctccagggtgcgcagccacccagtccgacgcccgccactgcccct cggtgcccctggcaggatgaggccttcatccggagggggggcccaggcaagggcccggag ctggggctgcgggcggtggccctgggcttcgaggaccctgaggtggccggggctgtcgga gcagcggaggtggcgcctgccgtggctaccaggagcaggcgggcctgctggcggcagctg gtgcaggtgttccagtcgaagcagttccgctcggccaagctggagcgcctgtaccagcgc tacttcttccagatgaaccagagcagcctgacgctgctcatggcggcgctcgtgctgctc acnnncgtgctgctggccttccacgcagcgcctgcccgccctcagcccgcctacgtggcc ctgctggcctgtgccgccaccctcttcgtggcactcatggtggtgtgcaaccggcacagc ttccgccaggactccatgtgggtggtgagctacgtggtgctgggcatcctggcggccgtg caggtcgggggcgccctggcagccgacccgcgtagtccctctgcaggcctctggtgccct gtgttctttgtctacatcacctacacactccttcccatccgtatgcgggctgcagtcttc agcggcctgggcctctccaccctgcacttggtcttggcctggcagctcaaccgtggtgac gccttcctctggaagcagcttggagccaacatgctgctgttcctctgcaccaatgtcatt ggcatctgcacacactatccggctgaggtgtctcagcgccaggcatttcaagagacccgc ggttacatccaggcccggctgcacctgcagcatgagaaccggcagcaggagcggctgctg ctgtctgtgttgccccagcatgttgccatggagatgaaagaagacatcaacacaaagaaa gaagacatgatgtttcataagatctacatccagaagcacgacaatgtcagcatcctgttt gcggacattgaaggcttcaccagcctggcgtcccagtgcacagcgcaggagctggtcatg accctgaacgagctctttgcccggttcgacaagctggctgcggaaaatcactgcctgagg atcaagatcttaggggactgttactactgcgtgtcagggctgccagaggcccgggcagac catgcccactgctgcgtggagatgggggtggacatgatcgaggctatctcgctggtgcgc gaggtgacaggtgtaaacgtgaacatgcgcgtgggcatccacagcgggcgtgtgcactgt ggcgtccttggcttgcggaaatggcagtttgatgtgtggtccaatgacgtgactctggcc aaccacatggaggccgggggccgggccggccgcatccacatcacccgggccacgctgcag tacctgaatggggactacgaagtggagccgggccgcggtggggagcgcaacgcctacctc aaggagcagcacattgagaccttcctcatcctgggagccagccagaaacggaaagaagag aaggccatgctggccaagctgcagcgggcacgggccaactccatggaagggctgatgcca cgctgggtgcctgaccgtgccttctcccggaccaaggactccaaggctttccgccagatg ggcatcgatgattccagcaaagacaaccggggtgctcaggatgccctgaaccctgaggat gaggtagacgagttcctgggccgggccattgatgcccgcagcattgatcagctgcgcaag gaccatgtgcgccggttcctgctcaccttccagagagaggatcttgaaaagaagtactca cgcaaggtggacccccgctttggagcctacgtggcctgtgccctgctggtcttctgcttc atctgcttcatccagcttgttgtcttcccacgctcagctctgatgcttgggatccacgcc agtatcttcctgctgttactggtcaccgtgctgacttgtgccgtgtactcctgtggctct ctgttccctgaggccctgcaacgtgtatctcgcagtatcgtccgctcgagggcacatagc accgcagttggcatcttttctgtcctgcttgtgttcacctccgccgttgccagcatgttc acctgtaaccacacccccttacgaacttgcgcagcccggatgctgaatttaacccctgct gacattaccgcctgccacctgcagcagctcaattactctctgggcctggatgctcccctg tgtgagggcaccgcacccacctgcagcttccctgagtacttcattgggaacgtgttgctg agtctcttggccagctctgtcttcctgcacatcagtagtatcgggaagttggccatgatc tttgtcctggggctcgtttatctggtgctgcttctgctgggtcccccagccaccatcttt gacaactatgacctcctgctgggcgtccacggcttggcttcttccaatgagacctttgat gggctggactgcccagcggccgggagggtggcactcaaatacatgacccccgtgattctg ctggtgtttgcactggcgctgtacctgcatgcccagcaggtggagtccaccgcccgcctg gacttcctctggaagctgcaggcaacaggggagaaggaagagatggaggagctccaggcc tacaaccggcggctgctacataacattctgcccaaggacgtggccgcccacttcctggcc cgggagcgccggaacgacgagctctactatcagtcctgtgaatgtgtggccgtcatgttt gcctccattgccaacttctctgagttctacgtggagctggaggccaacaacgagggtgtt gagtgcctgcgactgctcaatgagatcattgctgatttcgatgagatcatcagtgaggag cgcttccggcagctggagaagatcaagacaattggtagcacctacatggctgcctctggg ctgaacgccagcacctatgatcaggtgggccgctcccacatcactgccctcgccgactat gccatgcggctcatggagcagatgaagcacatcaatgagcactccttcaacaatttccag atgaagatcggactgaacatgggcccagttgtggcaggcgtcattggggctcggaagcca cagtatgacatctgggggaacacagtgaatgtctcgagtcgaatggacagcaccggggtc cctgaccgaatccaggtgaccacggacctgtaccaggttctagcggccaagggctaccag ctggaatgtcgaggggtggtcaaggtgaagggcaagggggagatgaccacctacttcctc aatgggggccccaggagttag

Bos indicus (zebu cattle): 109564199 Help Entry 109564199         CDS       T04792                                  Gene name ADCY4 Definition (RefSeq) adenylate cyclase type 4   KO K08044   adenylate cyclase 4 [EC:4.6.1.1] Organism biu  Bos indicus (zebu cattle) Pathway biu00230   Purine metabolism biu01100   Metabolic pathways biu01522   Endocrine resistance biu04015   Rap1 signaling pathway biu04020   Calcium signaling pathway biu04022   cGMP-PKG signaling pathway biu04024   cAMP signaling pathway biu04062   Chemokine signaling pathway biu04072   Phospholipase D signaling pathway biu04114   Oocyte meiosis biu04211   Longevity regulating pathway biu04213   Longevity regulating pathway - multiple species biu04261   Adrenergic signaling in cardiomyocytes biu04270   Vascular smooth muscle contraction biu04371   Apelin signaling pathway biu04540   Gap junction biu04611   Platelet activation biu04713   Circadian entrainment biu04714   Thermogenesis biu04723   Retrograde endocannabinoid signaling biu04724   Glutamatergic synapse biu04725   Cholinergic synapse biu04727   GABAergic synapse biu04742   Taste transduction biu04750   Inflammatory mediator regulation of TRP channels biu04911   Insulin secretion biu04912   GnRH signaling pathway biu04913   Ovarian steroidogenesis biu04914   Progesterone-mediated oocyte maturation biu04915   Estrogen signaling pathway biu04916   Melanogenesis biu04918   Thyroid hormone synthesis biu04921   Oxytocin signaling pathway biu04923   Regulation of lipolysis in adipocytes biu04925   Aldosterone synthesis and secretion biu04926   Relaxin signaling pathway biu04927   Cortisol synthesis and secretion biu04928   Parathyroid hormone synthesis, secretion and action biu04934   Cushing syndrome biu04935   Growth hormone synthesis, secretion and action biu04970   Salivary secretion biu04971   Gastric acid secretion biu04972   Pancreatic secretion biu04976   Bile secretion biu05032   Morphine addiction biu05163   Human cytomegalovirus infection biu05166   Human T-cell leukemia virus 1 infection biu05200   Pathways in cancer biu05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:biu00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     109564199 (ADCY4)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     109564199 (ADCY4)    04371 Apelin signaling pathway     109564199 (ADCY4)    04020 Calcium signaling pathway     109564199 (ADCY4)    04072 Phospholipase D signaling pathway     109564199 (ADCY4)    04024 cAMP signaling pathway     109564199 (ADCY4)    04022 cGMP-PKG signaling pathway     109564199 (ADCY4)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     109564199 (ADCY4)   09144 Cellular community - eukaryotes    04540 Gap junction     109564199 (ADCY4)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     109564199 (ADCY4)    04062 Chemokine signaling pathway     109564199 (ADCY4)   09152 Endocrine system    04911 Insulin secretion     109564199 (ADCY4)    04923 Regulation of lipolysis in adipocytes     109564199 (ADCY4)    04912 GnRH signaling pathway     109564199 (ADCY4)    04913 Ovarian steroidogenesis     109564199 (ADCY4)    04915 Estrogen signaling pathway     109564199 (ADCY4)    04914 Progesterone-mediated oocyte maturation     109564199 (ADCY4)    04921 Oxytocin signaling pathway     109564199 (ADCY4)    04926 Relaxin signaling pathway     109564199 (ADCY4)    04935 Growth hormone synthesis, secretion and action     109564199 (ADCY4)    04918 Thyroid hormone synthesis     109564199 (ADCY4)    04928 Parathyroid hormone synthesis, secretion and action     109564199 (ADCY4)    04916 Melanogenesis     109564199 (ADCY4)    04925 Aldosterone synthesis and secretion     109564199 (ADCY4)    04927 Cortisol synthesis and secretion     109564199 (ADCY4)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     109564199 (ADCY4)    04270 Vascular smooth muscle contraction     109564199 (ADCY4)   09154 Digestive system    04970 Salivary secretion     109564199 (ADCY4)    04971 Gastric acid secretion     109564199 (ADCY4)    04972 Pancreatic secretion     109564199 (ADCY4)    04976 Bile secretion     109564199 (ADCY4)   09156 Nervous system    04724 Glutamatergic synapse     109564199 (ADCY4)    04727 GABAergic synapse     109564199 (ADCY4)    04725 Cholinergic synapse     109564199 (ADCY4)    04723 Retrograde endocannabinoid signaling     109564199 (ADCY4)   09157 Sensory system    04742 Taste transduction     109564199 (ADCY4)    04750 Inflammatory mediator regulation of TRP channels     109564199 (ADCY4)   09149 Aging    04211 Longevity regulating pathway     109564199 (ADCY4)    04213 Longevity regulating pathway - multiple species     109564199 (ADCY4)   09159 Environmental adaptation    04713 Circadian entrainment     109564199 (ADCY4)    04714 Thermogenesis     109564199 (ADCY4)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     109564199 (ADCY4)   09165 Substance dependence    05032 Morphine addiction     109564199 (ADCY4)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     109564199 (ADCY4)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     109564199 (ADCY4)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     109564199 (ADCY4)    05163 Human cytomegalovirus infection     109564199 (ADCY4)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     109564199 (ADCY4) Enzymes [BR:biu01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      109564199 (ADCY4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc DUF1053 AC_N CD52 Motif Other DBs NCBI-GeneID:  109564199 NCBI-ProteinID:  XP_019823303 UniProt:  A0A6P5CCY5 LinkDB All DBs Position 10 AA seq 1039 aa AA seqDB search MARLFSPRQPPSEDLFYETYYSLSQQYPLLLLLLLIVLLGLLALLPVAWASGRELAADPA FLTTVLCALGGFSLLLVLASREQRLQRWTRPLSGLVWAALLALGHSFLFTGGVVSAWDQV SFFLFVIFTVYAMLPLDMRDAITAGVTSSLSHLLVLGLYLGPQPDSRPALLPQLAANAVL FLCGNAAGAYHKALMERALRATFREALSSLHSRRRLDTEKKHQEHLLLSILPAYLAREMK EEIMARLQAGQGSRPESTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKELVLMLNE LFGKFDQIAKEHECMRIKILGDCYYCVSGLPLSLPDHAINCVRMGLDMCRAIRKLRAATG VDINMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEASGVPGCPHMAQAAEEDEKG TAGGLLSSLEGSKMRPSLLMTRYLESWGAAKPFAHLSHVESPVSTSTPLPEKALSSFSPQ WSLDRSRTMRGPDEELDTGDAKFFQVIEQLNSQKQWKQSKDFNPLTLYFREKEMEKEYRL SALPAFKYYAACTFLVFLSNFIIQMLVTNRPPALTITYGITFLLFFLLLFVCFSEHLMKC VLKGPKMLHWLPTLSVLVATRPGLRVALGTATILLVFVMAITSLVFLPATSACPFQAPNM SSMASNLSWELPGSLPLISIPYSMHCCVLGFLSCSLFLHMSFELKLLLLLLWLTASCSIF LHSHAWLSDCLIARLYLGTLDSRPGVLKEPKLMGAVSFFIFFFTLLVLARQNEYYCRLDF LWKKKLRQEQEETETMENLTRLLLENVLPAHVAPQFIGQNRRNEDLYHQSYECVCVLFAS VPDFKEFYSESSINHEGLECLRLLNEIIADFDELLSKPKFSGVEKIKTICSTYMAATGLN ATSGQDAQQDAEQSCGHLGTMVEFAVALGSKLDVINKHSFNNFRLRVGLNHGPVVAGVIG AQKPQYDIWGNTVNVASRMESTGVLGKIQVTEETAWALQSLGYTCYSRGIIKVKGKGQLC TYFLNTDLTRTGPPSATLG NT seq 3120 nt NT seq  +upstreamnt  +downstreamnt atggcccgcctcttcagtccacggcagccccccagcgaagacctcttctacgagacctac tacagcttgagccagcagtacccactgctgctgctgctgctgctgatcgtgctcttgggg ctcctggcgctgctccctgtggcctgggcaagtggcagggagctggccgcagacccagcc ttcctgaccactgtgctgtgcgctctgggtggcttctcactgctgctggtcctggcttcc cgggagcagcgactgcagcgctggacgcgtcccctgtcaggcctcgtgtgggcagcactg cttgcactaggccacagcttcctgttcactgggggcgtggtgagcgcctgggaccaggtg tcctttttcctttttgtcatcttcactgtgtatgccatgttgcccttggacatgcgggac gccatcaccgcgggtgtcacctcctcactctcacacttgctggtccttgggctgtatctt gggcctcagcccgactctcggccggcgctgctgccacagctggctgcaaacgcggtgctg ttcctgtgcgggaacgcggccggagcctatcacaaggcgctgatggagcgcgcgctgcgc gccacgttccgggaggcgcttagttccctgcactcgcggcggagactggacaccgagaag aagcatcaggaacaccttctcttgtccatccttcctgcctacctggcccgagagatgaag gaggagatcatggcacggctgcaggctggacaggggtcacggccagagagcaccaacaac tttcacagcctctatgtcaagaggcaccagggagtcagcgtgctgtatgctgacatcgtg ggcttcacgagactggccagtgagtgctcccctaaggagttggtgcttatgctcaacgag ctctttggcaagttcgaccaaatcgccaaggagcacgaatgcatgcggatcaagatccta ggagactgttactactgtgtctccggcctgccgctctcactgcctgaccacgccatcaac tgtgtgcgcatggggctggacatgtgccgggccatcaggaaacttcgggcagccacaggc gtggatatcaacatgcgtgtgggcgtgcactcaggcagcgtgctctgcggggtcatcggg ctacagaaatggcagtatgatgtctggtcccatgacgtcactctggccaaccacatggag gcgagtggagtgccagggtgccctcatatggcccaggctgcagaggaggacgagaagggt actgcaggagggttgctgtcctctcttgagggctccaagatgcgtccatcactgctgatg acccgctacctggagtcctggggtgcagccaagcctttcgcccacctgagccacgtagag agccctgtgtccacatctacccctctcccggagaaggccctgtcttccttcagcccccag tggagcctggaccggagccgtaccatgaggggacctgatgaggaattagacactggggat gccaagttcttccaggtcatcgaacagctcaattctcagaaacaatggaaacagtcaaag gacttcaatccactgacactgtacttcagagagaaggagatggagaaagagtatcggctc tctgcactccccgccttcaaatactatgcagcctgcaccttcctggtttttctctccaac ttcattatccagatgctggtgacaaacaggcctccagctctgaccatcacctatggcatc accttcctcctcttcttcctcctcctcttcgtctgcttctcagagcacctgatgaagtgt gtcttgaaaggccccaagatgctgcactggctacccaccctgtctgtcctggtggccaca cggccaggactgcgagtggctctgggcaccgctaccatcctgctcgtcttcgtcatggcc attaccagtctggtcttcttaccagcaacatcagcctgcccttttcaggctcccaatatg tcctccatggcttccaacctctcctgggagctccctgggtccctgcctctcatcagcatc ccatactccatgcactgctgcgtgttgggcttcctctcctgctccctcttcctgcacatg agctttgagctgaagctgctgctgctcctgctgtggctgacggcctcctgctccatcttc ctgcactcccacgcctggttgtccgactgcctcatcgcccgcctctacctgggcaccttg gactccaggccaggggtgctgaaggagcccaaactgatgggagcagtctccttcttcatc ttcttcttcaccctcctagtcctggctcggcagaacgaatattactgccgcctggacttt ctgtggaagaagaagctgaggcaagagcaggaggagacagagacaatggagaacctgact cggctgctcttggagaacgtgctccctgcgcacgtggccccccagttcattggtcagaat cggcgcaatgaggacctctaccaccagtcctatgagtgtgtgtgtgtcctcttcgcctcg gtcccagacttcaaggagttctactctgaatccagcatcaaccatgaggggctagagtgt ctgcggctgctcaatgagataatcgctgattttgatgagctgctctccaagcccaagttc agtggggtggagaagatcaaaactatctgcagcacctacatggcagctaccggcttgaac gccacctctggacaggatgcacagcaggatgctgagcaaagctgcggccaccttggcacc atggtagagtttgctgtggcccttgggtctaagctggatgtcatcaacaagcactcattc aacaactttcgcttgcgtgtagggttaaaccacggacctgtagtggctggagtgattggg gcccagaaaccacaatatgacatctggggcaacacggtgaatgtggccagccgcatggag agcacaggtgtcctgggcaagattcaggtaacagaagagacagcctgggccctccagtcc ttaggctacacctgctacagccggggcatcatcaaggtcaaaggcaaagggcagctctgc acctacttcttgaacacagatttgacacgaactggacctccctcagccaccctaggctga

Bos indicus (zebu cattle): 109566330 Help Entry 109566330         CDS       T04792                                  Gene name ADCY3 Definition (RefSeq) adenylate cyclase type 3   KO K08043   adenylate cyclase 3 [EC:4.6.1.1] Organism biu  Bos indicus (zebu cattle) Pathway biu00230   Purine metabolism biu01100   Metabolic pathways biu01522   Endocrine resistance biu04015   Rap1 signaling pathway biu04020   Calcium signaling pathway biu04022   cGMP-PKG signaling pathway biu04024   cAMP signaling pathway biu04062   Chemokine signaling pathway biu04072   Phospholipase D signaling pathway biu04114   Oocyte meiosis biu04211   Longevity regulating pathway biu04213   Longevity regulating pathway - multiple species biu04261   Adrenergic signaling in cardiomyocytes biu04270   Vascular smooth muscle contraction biu04371   Apelin signaling pathway biu04540   Gap junction biu04611   Platelet activation biu04713   Circadian entrainment biu04714   Thermogenesis biu04723   Retrograde endocannabinoid signaling biu04724   Glutamatergic synapse biu04725   Cholinergic synapse biu04727   GABAergic synapse biu04740   Olfactory transduction biu04750   Inflammatory mediator regulation of TRP channels biu04911   Insulin secretion biu04912   GnRH signaling pathway biu04913   Ovarian steroidogenesis biu04914   Progesterone-mediated oocyte maturation biu04915   Estrogen signaling pathway biu04916   Melanogenesis biu04918   Thyroid hormone synthesis biu04921   Oxytocin signaling pathway biu04923   Regulation of lipolysis in adipocytes biu04925   Aldosterone synthesis and secretion biu04926   Relaxin signaling pathway biu04927   Cortisol synthesis and secretion biu04928   Parathyroid hormone synthesis, secretion and action biu04934   Cushing syndrome biu04935   Growth hormone synthesis, secretion and action biu04962   Vasopressin-regulated water reabsorption biu04970   Salivary secretion biu04971   Gastric acid secretion biu04972   Pancreatic secretion biu04976   Bile secretion biu05032   Morphine addiction biu05163   Human cytomegalovirus infection biu05166   Human T-cell leukemia virus 1 infection biu05200   Pathways in cancer biu05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:biu00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     109566330 (ADCY3)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     109566330 (ADCY3)    04371 Apelin signaling pathway     109566330 (ADCY3)    04020 Calcium signaling pathway     109566330 (ADCY3)    04072 Phospholipase D signaling pathway     109566330 (ADCY3)    04024 cAMP signaling pathway     109566330 (ADCY3)    04022 cGMP-PKG signaling pathway     109566330 (ADCY3)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     109566330 (ADCY3)   09144 Cellular community - eukaryotes    04540 Gap junction     109566330 (ADCY3)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     109566330 (ADCY3)    04062 Chemokine signaling pathway     109566330 (ADCY3)   09152 Endocrine system    04911 Insulin secretion     109566330 (ADCY3)    04923 Regulation of lipolysis in adipocytes     109566330 (ADCY3)    04912 GnRH signaling pathway     109566330 (ADCY3)    04913 Ovarian steroidogenesis     109566330 (ADCY3)    04915 Estrogen signaling pathway     109566330 (ADCY3)    04914 Progesterone-mediated oocyte maturation     109566330 (ADCY3)    04921 Oxytocin signaling pathway     109566330 (ADCY3)    04926 Relaxin signaling pathway     109566330 (ADCY3)    04935 Growth hormone synthesis, secretion and action     109566330 (ADCY3)    04918 Thyroid hormone synthesis     109566330 (ADCY3)    04928 Parathyroid hormone synthesis, secretion and action     109566330 (ADCY3)    04916 Melanogenesis     109566330 (ADCY3)    04925 Aldosterone synthesis and secretion     109566330 (ADCY3)    04927 Cortisol synthesis and secretion     109566330 (ADCY3)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     109566330 (ADCY3)    04270 Vascular smooth muscle contraction     109566330 (ADCY3)   09154 Digestive system    04970 Salivary secretion     109566330 (ADCY3)    04971 Gastric acid secretion     109566330 (ADCY3)    04972 Pancreatic secretion     109566330 (ADCY3)    04976 Bile secretion     109566330 (ADCY3)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     109566330 (ADCY3)   09156 Nervous system    04724 Glutamatergic synapse     109566330 (ADCY3)    04727 GABAergic synapse     109566330 (ADCY3)    04725 Cholinergic synapse     109566330 (ADCY3)    04723 Retrograde endocannabinoid signaling     109566330 (ADCY3)   09157 Sensory system    04740 Olfactory transduction     109566330 (ADCY3)    04750 Inflammatory mediator regulation of TRP channels     109566330 (ADCY3)   09149 Aging    04211 Longevity regulating pathway     109566330 (ADCY3)    04213 Longevity regulating pathway - multiple species     109566330 (ADCY3)   09159 Environmental adaptation    04713 Circadian entrainment     109566330 (ADCY3)    04714 Thermogenesis     109566330 (ADCY3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     109566330 (ADCY3)   09165 Substance dependence    05032 Morphine addiction     109566330 (ADCY3)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     109566330 (ADCY3)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     109566330 (ADCY3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     109566330 (ADCY3)    05163 Human cytomegalovirus infection     109566330 (ADCY3)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     109566330 (ADCY3) Enzymes [BR:biu01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      109566330 (ADCY3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N HNOBA Peptidase_S49_N Motif Other DBs NCBI-GeneID:  109566330 NCBI-ProteinID:  XP_019826170 UniProt:  A0A6P5CKI9 LinkDB All DBs Position 11 AA seq 1145 aa AA seqDB search MPRTQGFSEPEYSAXXXAEYSVSLPSDPDRGVGRTHEISVRNSGSCLCLXRFMRLTFVPE SLENLYQTYFKRQRHETLLVLVVFAALFDCYVVVMCAVVFSGDKLAPLAVAGVGLVLDII LFVLCKKGLLPNRVTRRVVPYLLWLLISAQVFSYLGLNFSRAHAASDTVGWQAFFVFSFF ITLPLSLSPIVIISVVSCVVHTLVLGVTVAQQQQDGLKGVQLLREILANVFLYLCAIVVG IMSYYMADRKHRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKDMKKDES QKDQQQFNTMYMYRHENVSILFADIVGFTQLSSACSAQELVKLLNELFARFDKLAAKYHQ LRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAISYVREKTKTGVDMRVGVHTGTV LGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTMDCLKGEFDVEPGEGGSRCD YLEEKGIETYLIIASKPEVKKTAAQNGLNGSALLNGAPPSSKPSSPALIETKESNGSIHT SGSISEEPEEQDAQADNPSFPNPRRRLRLQDLADRVVDASEDEHELNQLLNEALLERESA QVVKKRNTFLLSMRFMDPEMETRYSVEKEKQSGAAFSCSCVVLLCTAVVEILIDPWLMTN YVTFVVGEALLLILTICSLAAIFPRAFPKKLVAFSTWIDRTRWARNTWAMLAIFILVMAN VVDMLSCLQYYTGPTNGTAEMQVEDGCVENPKYYNYVAVLSLIATIMLVQVSHMVKLTLM LLIAGAVAVINIYAWCPIFDDYDRKRFQQHDFPMVALEKMQVFSSSGLNGTDRLPLVPSK YSMTVMIFVMMLSFYYFSRHVEKLARTLFLWKIEVHDQKERVYEMRRWNEALVTNMLPEH VARHFLGSKKRDEELYSQSYDEIGVMFASLPNFADFYTEESINNGGIECLRFLNEIISDF DSLLDNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFTSSNKDEKSDKERWQHLADLADF ALAMKDTLTNINNQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGV MGNIQVVEETQVILREYGFRFVRRGPIFVKGKGELLTFFLKGRDKLATFPNGASITLPHQ VVDNS NT seq 3438 nt NT seq  +upstreamnt  +downstreamnt atgccgaggacccagggcttctccgagccygagtactccgcggnnnnnncggccgagtac tctgtcagcctgccttcggacccggaccgcggggtgggccggacccatgaaatctctgtc cggaactcggggtcgtgcctctgcttgcstcgcttcatgcggctgaccttcgtaccagag tccttggagaacctgtaccagacctacttcaagaggcagcgccacgagaccctgctggtg ctggtggtcttcgcggccctcttcgactgctatgtggtggtcatgtgcgctgtggtcttc tctggcgacaagctggcccccctggccgtggctggggtcgggctggtgttggacatcatc cttttcgtgctctgcaaaaaggggctgctccccaaccgggtcactcggagagtggtgccc tacctgctgtggctgctgatatcagcccaggtcttctcctacctgggcctgaacttctcc cgtgcccaygcggccagcgacacggtgggctggcaggccttcttcgtcttctccttcttc atcacgctgccgctcagcctcagccccattgtcatcatctccgtggtctcctgcgtcgtg cacacactcgtcttgggggtcactgtggcccagcarcagcaggatgggctgaagggagtg cagttgctgagggagattctggccaacgtcttcctctacctgtgcgccatcgtcgtgggc atcatgtcctactacatggcagaccgcaagcaccgcaaggccttcctggaggcccgccag tctctggaggtgaagatgaacctggaggagcagagtcagcagcaggagaaccttatgctc tccatcctgcccaagcacgtggccgacgagatgctgaaggacatgaagaaggatgagagc cagaaggaccagcagcagttcaacaccatgtacatgtaccgccatgagaacgtcagcatc ctctttgctgatatcgtgggcttcacccagctgtcctcagcctgcagcgcccaggagctt gtgaagctgctcaatgagctctttgcccgcttcgacaagctggcggctaaataccaccag ctgcggattaagatcctgggcgactgttactactgcatctgtgggctgcctgactaccgg gaggaccacgccgtctgctccatcctcatggggctcgccatggtggaggccatctcgtat gtgcgggagaagacgaagaccggggtggacatgcgcgtgggggtgcacacgggcaccgtg ctggggggcgtcctyggccagaaacgctggcagtacgacgtgtggtccaccgacgtcacc gtggccaacaagatggaggctggcggcatccctgggcgtgtgcacatctcccagagcacc atggactgcctgaaaggagagttcgacgtggagccgggcgaggggggcagtcgctgtgat tacctggaagagaagggcattgagacctacctcatcatcgcttccaagccagaggtgaag aagacagctgcccaaaatggcctcaacggctcggccctgctgaacggagcgccgccktcc tcaaagcccagctcccctgccctcattgagaccaaggagtccaacgggagcattcacacc agcggctctatatctgaggagccygaggagcaagatgcccaggccgacaacccctcgttc cccaaccctcgccggaggctgcgccttcaggacctggctgatcgcgtggtggacgcctcc gaggacgagcatgagctcaaccagctactcaacgaggcgctgctagagcgggagtctgcc cargtagtgaagaagagaaacaccttcctcctgtccatgcggttcatggaccccgagatg gaaacccgctactcggtggagaaggagaagcaragcggggctgccttcagctgctcctgc gttgtcctactctgcacggccgtggtggagatcctcattgacccctggctcatgacgaac tatgtgacctttgtggttggggaggctctgctcctgatcctgacaatctgctcgctggct gccatctttccgcgggcctttcctaagaagctcgtggccttctctacttggattgaccgg acgcgctgggccaggaacacctgggccatgctggccatcttcattcttgtcatggcaaac gtggtggacatgctcagctgtctccagtactacacaggacccaccaacggcaccgcagag atgcaggtggaggatggctgcgtggagaaccccaagtattacaactacgtggccgtgctg tccctcatcgccaccatcatgctggtgcaggtcagccacatggtcaagctcacactcatg ctgctcatcgcgggggccgtggctgtcatcaacatctacgcctggtgccccatctttgac gactacgaccgcaaacgcttccagcaacacgactttccgatggtggccttagagaagatg caggtgttttccagctcggggctcaatggcactgacaggctgcccctggtgccgtctaag tactcgatgacagtgatgatctttgtcatgatgctgagcttttactacttctcccgccac gtggaaaagctggcacggacactgttcttgtggaagattgaggtccacgaccagaaggaa cgtgtctatgagatgcgacgctggaatgaagccttggtcaccaacatgctacctgaacac gtggcacgccatttcctggggtccaagaagagagatgaggagctgtacagccagtcttat gatgagattggagttatgtttgcctccctgcccaattttgctgacttctacacagaggag agcatcaataacggtggcattgagtgtctacgcttcctcaatgagatcatctcagatttt gactctcttctggacaatcccaagttccgggtcatcaccaagatcaagaccattggtagc acctacatggcagcttcaggagtcaccccagatgtcaacaccaatggctttaccagctcc aacaaggacgagaagtcagacaaggagcgctggcagcacctggcagatctggccgatttt gcgctggccatgaaggacacgctcaccaacatcaacaaccagtccttcaacaacttcatg ctgcgcattggaatgaacaaaggaggggtcctggctggggtcattggagcccggaaacca cactatgacatctggggcaacacagtcaacgtagccagcaggatggagtccacaggggtc atgggcaacatccaggtggtggaagaaacccaagtcatccttcgagaatacggcttccgc ttcgtgaggagagggcccatctttgtgaaagggaagggggaactgctaacctttttcttg aagggccgagacaagctggccacattccctaacggcgcctcaatcacactgcctcaccag gtggtagacaactcctga

Bos indicus (zebu cattle): 109568647 Help Entry 109568647         CDS       T04792                                  Gene name ADCY8 Definition (RefSeq) adenylate cyclase type 8 isoform X1   KO K08048   adenylate cyclase 8 [EC:4.6.1.1] Organism biu  Bos indicus (zebu cattle) Pathway biu00230   Purine metabolism biu01100   Metabolic pathways biu01522   Endocrine resistance biu04015   Rap1 signaling pathway biu04020   Calcium signaling pathway biu04022   cGMP-PKG signaling pathway biu04024   cAMP signaling pathway biu04062   Chemokine signaling pathway biu04072   Phospholipase D signaling pathway biu04114   Oocyte meiosis biu04211   Longevity regulating pathway biu04213   Longevity regulating pathway - multiple species biu04261   Adrenergic signaling in cardiomyocytes biu04270   Vascular smooth muscle contraction biu04371   Apelin signaling pathway biu04540   Gap junction biu04611   Platelet activation biu04713   Circadian entrainment biu04714   Thermogenesis biu04720   Long-term potentiation biu04723   Retrograde endocannabinoid signaling biu04724   Glutamatergic synapse biu04725   Cholinergic synapse biu04727   GABAergic synapse biu04742   Taste transduction biu04750   Inflammatory mediator regulation of TRP channels biu04911   Insulin secretion biu04912   GnRH signaling pathway biu04913   Ovarian steroidogenesis biu04914   Progesterone-mediated oocyte maturation biu04915   Estrogen signaling pathway biu04916   Melanogenesis biu04918   Thyroid hormone synthesis biu04921   Oxytocin signaling pathway biu04923   Regulation of lipolysis in adipocytes biu04925   Aldosterone synthesis and secretion biu04926   Relaxin signaling pathway biu04927   Cortisol synthesis and secretion biu04928   Parathyroid hormone synthesis, secretion and action biu04934   Cushing syndrome biu04935   Growth hormone synthesis, secretion and action biu04970   Salivary secretion biu04971   Gastric acid secretion biu04972   Pancreatic secretion biu04976   Bile secretion biu05032   Morphine addiction biu05163   Human cytomegalovirus infection biu05166   Human T-cell leukemia virus 1 infection biu05200   Pathways in cancer biu05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:biu00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     109568647 (ADCY8)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     109568647 (ADCY8)    04371 Apelin signaling pathway     109568647 (ADCY8)    04020 Calcium signaling pathway     109568647 (ADCY8)    04072 Phospholipase D signaling pathway     109568647 (ADCY8)    04024 cAMP signaling pathway     109568647 (ADCY8)    04022 cGMP-PKG signaling pathway     109568647 (ADCY8)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     109568647 (ADCY8)   09144 Cellular community - eukaryotes    04540 Gap junction     109568647 (ADCY8)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     109568647 (ADCY8)    04062 Chemokine signaling pathway     109568647 (ADCY8)   09152 Endocrine system    04911 Insulin secretion     109568647 (ADCY8)    04923 Regulation of lipolysis in adipocytes     109568647 (ADCY8)    04912 GnRH signaling pathway     109568647 (ADCY8)    04913 Ovarian steroidogenesis     109568647 (ADCY8)    04915 Estrogen signaling pathway     109568647 (ADCY8)    04914 Progesterone-mediated oocyte maturation     109568647 (ADCY8)    04921 Oxytocin signaling pathway     109568647 (ADCY8)    04926 Relaxin signaling pathway     109568647 (ADCY8)    04935 Growth hormone synthesis, secretion and action     109568647 (ADCY8)    04918 Thyroid hormone synthesis     109568647 (ADCY8)    04928 Parathyroid hormone synthesis, secretion and action     109568647 (ADCY8)    04916 Melanogenesis     109568647 (ADCY8)    04925 Aldosterone synthesis and secretion     109568647 (ADCY8)    04927 Cortisol synthesis and secretion     109568647 (ADCY8)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     109568647 (ADCY8)    04270 Vascular smooth muscle contraction     109568647 (ADCY8)   09154 Digestive system    04970 Salivary secretion     109568647 (ADCY8)    04971 Gastric acid secretion     109568647 (ADCY8)    04972 Pancreatic secretion     109568647 (ADCY8)    04976 Bile secretion     109568647 (ADCY8)   09156 Nervous system    04724 Glutamatergic synapse     109568647 (ADCY8)    04727 GABAergic synapse     109568647 (ADCY8)    04725 Cholinergic synapse     109568647 (ADCY8)    04720 Long-term potentiation     109568647 (ADCY8)    04723 Retrograde endocannabinoid signaling     109568647 (ADCY8)   09157 Sensory system    04742 Taste transduction     109568647 (ADCY8)    04750 Inflammatory mediator regulation of TRP channels     109568647 (ADCY8)   09149 Aging    04211 Longevity regulating pathway     109568647 (ADCY8)    04213 Longevity regulating pathway - multiple species     109568647 (ADCY8)   09159 Environmental adaptation    04713 Circadian entrainment     109568647 (ADCY8)    04714 Thermogenesis     109568647 (ADCY8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     109568647 (ADCY8)   09165 Substance dependence    05032 Morphine addiction     109568647 (ADCY8)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     109568647 (ADCY8)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     109568647 (ADCY8)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     109568647 (ADCY8)    05163 Human cytomegalovirus infection     109568647 (ADCY8)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     109568647 (ADCY8) Enzymes [BR:biu01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      109568647 (ADCY8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N DUF1053 TBK1_ULD Motif Other DBs NCBI-GeneID:  109568647 NCBI-ProteinID:  XP_019829623 UniProt:  A0A6P5CVG6 LinkDB All DBs Position 14 AA seq 1253 aa AA seqDB search MELSDVRCLSGSEELYTIHPTPPAGDSGSGSRPQRLLWQTAVRHITEQRFIHGHRGGGGG GGNGSSSKASDPGGGGPNHHHASQLSGDSALPLYALGPGERAHGTGGPKVFPERSGSGSA SGSGGGGDLGFLHLDCAPSNSDFFLNGGYSYRGVIFPTLRNSFKSRDLERLYQRYFLGQR RKSEVVMNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGFFTGIEVVICALVVVRKDTTS HTYLQYSGVVTWVAMTTQILAAGLGYGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLG TSLMQVVLQAVIPRLAVISINQVVAQAVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVE ARLRLETENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFA DVKGFTNLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQDH AHCCVEMGLSMIKTIRYVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIAN KLESGGIPGRIHISKATLDCLNGDYNVEEGHGKERNEFLRKHNIETYLIKQPEESLLSLP EDIVKESVSSSDRRNSGATFTEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHLAQAL HVQSGPEEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLVC AFIVLLFITAIQSLLPSSRVMPMAIQFSILIMLHSALVLITTAEDYKCLPLVLRKTCCWI NETYLARNVIIFASILINFLGAILNILWCDFDKSIPLKNLTFNSSAVFTDICSYPEYFVF TGVLAMVTCAVFLRLNSVLKLAVLLIMIAIYALLTETIYAGLFLRYDNLNHSGEDFLGTK EASLLLMAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSH VARHFLEKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADF DELLGEDRFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWGHLCALADFSLALTESIQEIN KHSFNNFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPEETYL ILKDQGFAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPFILPPRRLPGQYSLAAVVLG LVQSLNRQRQKQLLNENNNTGIIKGHYNRRTLLTPSGPEPGAPAEGADKPELP NT seq 3762 nt NT seq  +upstreamnt  +downstreamnt atggagctctccgatgtgcgctgcctgagcggcagcgaggaactctacaccatccacccg acgcccccggccggcgacagcgggagcggctcccggccgcagcggctgctgtggcagacg gcggtgcggcacatcaccgagcagcgcttcatccatgggcaccgcggcggcggcggcggt ggcgggaacggaagctccagcaaagcctcggaccccggaggcggcggacccaaccaccac cacgcgtcgcagctgtccggcgactcggcgctgcccctctacgcgctgggccctggggag cgagcgcacggcaccggcggccccaaagtcttcccggaacgcagcgggagcggcagcgcc agcggcagcggcggcgggggagacctgggcttcctgcacctcgactgcgccccgagcaac tcggatttcttcctcaatgggggctacagctaccgaggggtcattttccccaccctgcgc aactccttcaagtcccgggatctggagcgcctctaccagcgctatttcctgggccagagg cgcaaatcggaggtggtgatgaacgtgctggacgtgctgaccaaactcaccctcctggtt ctccacttgagcctggcctcggcccccatggacccgctcaagggcatcctgctgggcttc ttcaccggcatagaggtggtgatctgcgccctggtggtggtcagaaaggacaccacctcg cacacatacctgcagtacagcggtgtggtcacttgggtggccatgaccacccagatctta gcagcagggctcggctatgggctcctgggagacggcatcggctacgtgctsttcaccctt tttgccacstacagcatgctgccgctgccgctcacctgggccatcctggccggcctaggc acctctttgatgcaggtggtcctccaagcggtcatccccaggctggcggtcatttccatc aatcaggttgtggcccaggcagtgttattcatgtgtatgaacacagctggaatcttcatc agttacctgtcagaccgggcccagcgccaggccttcctggagacacggaggtgtgtggag gccaggctgcgcctggagacggaaaaccaaagacaggagcgacttgtgctgtccgtgctt ccycgttttgttgtcctggagatgatcaatgacatgaccaacgtggaagacgagcaccta cagcatcagttccaccggatctacatccatcgctacgagaatgtcagtattctttttgca gatgttaaaggatttaccaacctctccacgaccttgtctgctcaggagctggtcaggatg ctcaacgagctctttgccagatttgatcgactggcccatgagcatcactgccttcgtatt aaaatcctgggggactgctactactgcgtttcaggacttcctgagccccgccaggaccac gcccactgctgtgttgaaatgggcctcagcatgatcaaaactatcaggtatgtgcgatca aggacaaagcacgatgttgacatgcggattggaatccactcgggctcggtgctgtgcggt gtgttgggtcttcggaagtggcagtttgatgtctggtcttgggatgtggacatcgcgaac aaacttgaatctggaggaatccccgggcggattcacatttccaaggccacgctggactgc ctcaacggtgactataatgtggaagagggtcacggtaaagagaggaatgaattcttgagg aagcataatatagagacctatttaattaagcagcctgaggagagtctgctgtctttgccc gaagacatcgtcaaggagtctgtgagctcctcagacaggagaaacagcggggcgacgttc acagagggatcttggagccctgaattgcccttcgataacatagtggggaaacagaacact ctggctgccctaacaagaaattcaataaatctacttccaaaccatcttgcacaagctttg catgtccagtctgggcctgaggaaattaacaagagaatagaacataccatcgacttgcgg agtggtgataaattgagaagagagcatatcaagccattctcactgatgtttaaagactcc agcctggagcacaagtattctcaaatgagggatgaagtattcaaatcaaacttggtctgt gcgtttatcgttcttctatttatcacggcaatacaaagcttgcttccttcttcaagggtg atgcccatggccatccagttttccatcctgatcatgctgcactcagctctggtcctcatc actacggcagaggattacaagtgtttgcccctggtcctccggaaaacctgctgttggatt aacgagacctatttggccaggaacgtcatcatctttgcatccatcttgattaatttcctg ggcgccatcctaaatatcctgtggtgtgattttgacaagtcgatacccttgaagaacctg actttcaattcctcagctgtgtttacagatatctgctcctacccagagtactttgtcttc acgggggtgctggccatggtgacctgtgcggttttcctccgactcaactctgtccttaag ctggctgtgctcctgatcatgattgccatctacgccctgctgaccgagaccatctatgca ggcctcttcctgcgctacgacaacctgaaccacagcggagaagatttcctggggaccaag gaagcgtcactgctgctaatggccatgtttcttcttgccgttttctaccatggacagcag ctggagtacacagcccgcctggacttcctgtggcgagtccaggccaaagaggagatcaac gagatgaaagagctgagggagcacaatgagaacatgctgcggaacatcctgcccagccac gtggcccgccacttcctggagaaggaccgggacaatgaggagctgtattctcaatcctat gacgccgtcggggtgatgtttgcctccatcccggggtttgcagacttttactctcagacc gaaatgaacaaccaaggagtggagtgcctccgcctactgaatgagatcattgctgacttc gatgagctgctcggtgaagaccggtttcaagacattgaaaagattaagaccattggtagt acctacatggccgtgtcaggcctgtcacctgaaaagcagcaatgcgaggataagtggggg catttgtgcgccctggccgacttctccctcgccctgactgaaagcatccaggagatcaac aagcattccttcaacaatttcgagctccggattggcatcagccacggctcagtggtagcc ggtgtcatcggcgctaagaaaccacagtacgacatttggggcaaaaccgtgaacctggcg agtcggatggacagcacaggggtcagcggcaggatccaggtcccggaggagacctacctc atcctgaaggaccagggctttgcctttgactaccgaggggagatctatgtgaagggcatc agcgaacaggaagggaaaatcaaaacgtactttctcctgggaagagtccagcccaacccc ttcatcctgccccccaggagactgcccggacagtactccttggccgcggtcgtcctgggc ctcgtccagtccctcaacaggcagaggcagaagcagctgctgaacgagaacaacaacacg ggcattatcaagggccactacaaccggcggactttgctgacgcccagcgggcccgagccg ggagccccagccgaaggcgccgacaagcccgagttgccataa

Bos indicus (zebu cattle): 109572478 Help Entry 109572478         CDS       T04792                                  Gene name ADCY7 Definition (RefSeq) adenylate cyclase type 7 isoform X1   KO K08047   adenylate cyclase 7 [EC:4.6.1.1] Organism biu  Bos indicus (zebu cattle) Pathway biu00230   Purine metabolism biu01100   Metabolic pathways biu01522   Endocrine resistance biu04015   Rap1 signaling pathway biu04020   Calcium signaling pathway biu04022   cGMP-PKG signaling pathway biu04024   cAMP signaling pathway biu04062   Chemokine signaling pathway biu04072   Phospholipase D signaling pathway biu04114   Oocyte meiosis biu04211   Longevity regulating pathway biu04213   Longevity regulating pathway - multiple species biu04261   Adrenergic signaling in cardiomyocytes biu04270   Vascular smooth muscle contraction biu04371   Apelin signaling pathway biu04540   Gap junction biu04611   Platelet activation biu04713   Circadian entrainment biu04714   Thermogenesis biu04723   Retrograde endocannabinoid signaling biu04724   Glutamatergic synapse biu04725   Cholinergic synapse biu04727   GABAergic synapse biu04750   Inflammatory mediator regulation of TRP channels biu04911   Insulin secretion biu04912   GnRH signaling pathway biu04913   Ovarian steroidogenesis biu04914   Progesterone-mediated oocyte maturation biu04915   Estrogen signaling pathway biu04916   Melanogenesis biu04918   Thyroid hormone synthesis biu04921   Oxytocin signaling pathway biu04923   Regulation of lipolysis in adipocytes biu04925   Aldosterone synthesis and secretion biu04926   Relaxin signaling pathway biu04927   Cortisol synthesis and secretion biu04928   Parathyroid hormone synthesis, secretion and action biu04934   Cushing syndrome biu04935   Growth hormone synthesis, secretion and action biu04970   Salivary secretion biu04971   Gastric acid secretion biu04972   Pancreatic secretion biu04976   Bile secretion biu05032   Morphine addiction biu05163   Human cytomegalovirus infection biu05166   Human T-cell leukemia virus 1 infection biu05200   Pathways in cancer biu05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:biu00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     109572478 (ADCY7)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     109572478 (ADCY7)    04371 Apelin signaling pathway     109572478 (ADCY7)    04020 Calcium signaling pathway     109572478 (ADCY7)    04072 Phospholipase D signaling pathway     109572478 (ADCY7)    04024 cAMP signaling pathway     109572478 (ADCY7)    04022 cGMP-PKG signaling pathway     109572478 (ADCY7)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     109572478 (ADCY7)   09144 Cellular community - eukaryotes    04540 Gap junction     109572478 (ADCY7)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     109572478 (ADCY7)    04062 Chemokine signaling pathway     109572478 (ADCY7)   09152 Endocrine system    04911 Insulin secretion     109572478 (ADCY7)    04923 Regulation of lipolysis in adipocytes     109572478 (ADCY7)    04912 GnRH signaling pathway     109572478 (ADCY7)    04913 Ovarian steroidogenesis     109572478 (ADCY7)    04915 Estrogen signaling pathway     109572478 (ADCY7)    04914 Progesterone-mediated oocyte maturation     109572478 (ADCY7)    04921 Oxytocin signaling pathway     109572478 (ADCY7)    04926 Relaxin signaling pathway     109572478 (ADCY7)    04935 Growth hormone synthesis, secretion and action     109572478 (ADCY7)    04918 Thyroid hormone synthesis     109572478 (ADCY7)    04928 Parathyroid hormone synthesis, secretion and action     109572478 (ADCY7)    04916 Melanogenesis     109572478 (ADCY7)    04925 Aldosterone synthesis and secretion     109572478 (ADCY7)    04927 Cortisol synthesis and secretion     109572478 (ADCY7)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     109572478 (ADCY7)    04270 Vascular smooth muscle contraction     109572478 (ADCY7)   09154 Digestive system    04970 Salivary secretion     109572478 (ADCY7)    04971 Gastric acid secretion     109572478 (ADCY7)    04972 Pancreatic secretion     109572478 (ADCY7)    04976 Bile secretion     109572478 (ADCY7)   09156 Nervous system    04724 Glutamatergic synapse     109572478 (ADCY7)    04727 GABAergic synapse     109572478 (ADCY7)    04725 Cholinergic synapse     109572478 (ADCY7)    04723 Retrograde endocannabinoid signaling     109572478 (ADCY7)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     109572478 (ADCY7)   09149 Aging    04211 Longevity regulating pathway     109572478 (ADCY7)    04213 Longevity regulating pathway - multiple species     109572478 (ADCY7)   09159 Environmental adaptation    04713 Circadian entrainment     109572478 (ADCY7)    04714 Thermogenesis     109572478 (ADCY7)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     109572478 (ADCY7)   09165 Substance dependence    05032 Morphine addiction     109572478 (ADCY7)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     109572478 (ADCY7)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     109572478 (ADCY7)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     109572478 (ADCY7)    05163 Human cytomegalovirus infection     109572478 (ADCY7)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     109572478 (ADCY7) Enzymes [BR:biu01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      109572478 (ADCY7) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc DUF1053 AC_N Motif Other DBs NCBI-GeneID:  109572478 NCBI-ProteinID:  XP_019834853 UniProt:  A0A6P5D980 LinkDB All DBs Position 18 AA seq 1097 aa AA seqDB search MLPRPWGFLRGPLGVPRWRMPAKGRYFLNEGEEGPDQDALYEKYRLTSQHGPLLLMLLLV AIAACTTLIVITFSYGDPSRHRAVLGTAFFTLAXFVLLYALVYVECLDRRGLRISALLIW ACLVTLGYVLVFDFDSPRKDTCVLGQVPFFLFVVFVVYTLLPFSMWGAVTAGLVSSISHL LVLAMHQEDFTSPVGLKLLATAVVFVCGNLTGAFHKHHMQDASHDLFTYTVKCIQIRRKL RIEKRQQENLLLSVLPAHISMGMKLAIIERLKERGDRRYLPDNNFHNLYVKRHQNVSILY ADIVGFTRLASDCSPKELVVVLNELFGKFDQIAKANECMRIKILGDCYYCVSGLPVSLPN HARNCVKMGLDMCEAIKQVREATGVDISMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLA NRMEAAGVPGRVHITEATLKHLDKAYEVEDGHGQQRDPYLKEMNIRTYLVIDPRSQQPPQ PSQHNSKNKGDATLKMRASVRMTRYLESWGAARPFAHLNQRESVSSSETLVSHGRRPKAV PLRRHRTPDRSASPKGRSEDDSYDDEMLSAIEGLSSTRPCCSKSDDFXTFGSIFLEKGFE REYRLAPIPRVRYYFACASLVFVCILLIHVLLLYSMKTLGVSFGLVACVLGLVLGLCFAD VFLRCCPALGKLRAIAESVETQPLLRVSLAILTIGSLLVIAVVNLPLMPFRDRGLTAGNE TGLRAVSGWEMSPCYLLPYYTCSCILAFIACSVFLRMSLELKVVLLTVALVAYLVLFNVY PSWQWDCSGHSLGNLTGTNGTLSSSSSCSWHLKTMTNFYLVLFYTTLIXLSRQIDYYCRL DCLWKKKFKKEHEEFETMENVNRLLLENVLPAHVAAHFIGDKLNEDWYHQSYDCVCVMFA SVPDFKVFYTECDVNKEGLECLRLLNEIIADFDELLLKPKFSGVEKIKTIGSTYMAAAGL SVPSGPENQDLERQHAHIGIMVEFSTALMSKLDGINRHSFNSFRLRVGINHGPVIAGVIG ARKPQYDIWGNTVNVASRMESTGELGKIQVTEETCTILQGLGYSCECRGLIDVKGKGELR TYFVCTDTAKFQGLGLN NT seq 3294 nt NT seq  +upstreamnt  +downstreamnt atgctccccaggccgtggggtttcctgcgtggaccactgggtgtgccaaggtggaggatg ccagccaaggggcgctacttcctcaacgagggcgaggagggccccgaccaggatgcgctc tacgagaagtaccgcctcaccagccagcacgggccactcctgctcatgctcctgttggtg gccatcgctgcctgcaccacgctcatcgtcatcaccttcagctayggggacccctccaga caccgggccgtcctggggacggcgttcttcacgctcgccrtgtttgtgctcctctacgct ctggtgtacgttgagtgcctcgaccggcgggggctcaggatttccgcgctgctcatctgg gcctgccttgtgacgctgggctacgtgttggtgtttgatttcgactcgccgaggaaggac acctgtgtcttggggcaggtgcccttcttcctgttcgtggtcttcgtggtgtacacgctg ctgcccttcagcatgtggggcgccgtcacggccggactcgtctccagcatctcccacctc ctggtgctcgcaatgcaccaggaagacttcaccagccctgtggggctgaagctgctggcc actgcggtggtcttcgtgtgcgggaacctcacaggcgccttccacaagcaccacatgcag gacgcctcccacgacctcttcacctacacagtgaagtgcatccagattcggcgtaagctg cgcatcgagaagcgccagcaggagaacctgctgctgtctgtgctgcctgcccacatctcc atgggcatgaagctggccatcatcgagcggctcaaggagcgcggggaccgccgttacctg cccgacaacaacttccacaacctctacgtcaagaggcaccagaatgtcagcatcctctac gctgacatcgtgggcttcacgcgactggccagtgactgctcccccaaagagctggtggtg gtgctgaatgagctcttcggcaagtttgaccagatcgccaaggccaacgagtgcatgcgg attaagatcctgggwgactgctactactgcgtgtccggcttgcctgtgtccctgcccaac cacgcccgtaactgtgtgaagatggggctggacatgtgtgaggccatcaagcaggtgcgg gaggccacaggcgtggacatcagcatgcgcgtgggcatccactcggggaacgtgctgtgc ggcgtcatcgggctgcgcaagtggcagtacgacgtgtggtcccacgatgtgtccctggcc aacaggatggaggcggccggagtccctggccgggtgcacatcacagaggcgacgctgaag cacctggacaaggcgtatgaggtggaggacgggcacgggcagcagcgggacccttacctc aaagagatgaacatccgcacctacctggtcatcgacccccggagccagcagccgccccag cccagccagcacaactccaagaacaagggggacgcgaccctgaagatgcgggcgtccgtg cgcatgacgcgctacctggagtcctggggggcggctcgccccttygcgcacctcaaccaa cgcgagagcgtgagcagcagtgagacccttgtgtcccatgggcggaggcccaaggctgtt cccctgaggcgccatcggacccctgacagaagygcatcccccaaggggcggtcagaggac gactcatacgatgatgagatgctgtcagccatcgaggggctcagctctaccagaccctgc tgctccaagtctgatgacttcyccacctttgggtccatcttcctggagaagggcttcgag cgagagtaccgcctggcgcccatcccccgggtccgctactacttcgcttgtgccagcctc gtcttcgtctgcatcctgctcatccacgtcttgctgttgtacagtatgaagactctgggc gtgtcctttgggctggtggcctgtgtgcttgggctggtactaggcttgtgcttygccgat gtgttcttgaggtgctgcccggccctggggaagctccgagccattgccgagagcgtggag acgcagcccctgctgcgggtgtccctggccatcctgaccatcggcagcctgctcgtcatt gctgtcgtcaacctgcccctgatgcccttccgggaccgggggctgactgctgggaacgag acgggcctgagggctgtgagcggctgggagatgagcccgtgctacctcctcccgtactac acctgcagctgcatcctggccttcatcgcttgctctgtcttcctgcggatgagcctggag ctgaaggtcgtgctgctgaccgtggccttggtggcctacctggtcctcttcaacgtctac ccgagctggcagtgggactgcagtggccacagcctgggcaacctcaccgggaccaatggc accctcagcagctcctcatcctgttcatggcatctgaagacgatgaccaatttctacctg gtcttgttctacaccaccctcatcatsctctccagacagattgactattattgccgcctg gactgtctgtggaagaagaagttcaagaaggaacacgaggagtttgaaacaatggagaat gtgaaccgccttcttctagagaatgtcctgcccgcgcacgtggccgcccacttcatcggt gacaagttaaatgaggactggtaccatcagtcctacgactgcgtgtgtgtcatgtttgcg tcggtgccggactttaaagtcttctacacagagtgcgacgtcaacaaggaagggctggag tgcctgcgcctgctcaacgagatcatcgcygactttgacgagctgctgttaaagcctaag ttcagtggtgtggagaagatcaagaccatcggcagcacgtacatggccgctgcggggctc agcgtcccctcggggcctgagaaccaggacctggagcggcagcacgcccacatcggcatc atggtagagttcagcaccgccctgatgagcaagctggacggcatcaatcggcactccttc aactcctttcgcctccgagtcggcataaaccatgggcctgtgattgctggagtgattggg gcacgaaaacctcagtacgacatctggggaaacacggtcaatgttgccagtcgaatggag agcactggagaacttggaaaaatccaggttactgaagagacatgtaccatcctccaggga ctagggtattcctgtgagtgccgcgggctgattgacgtcaaaggcaaaggtgaactgagg acttactttgtctgtacggacaccgccaagttccaaggcctggggctgaactga

Bos indicus (zebu cattle): 109574822 Help Entry 109574822         CDS       T04792                                  Gene name ADCY2 Definition (RefSeq) adenylate cyclase type 2   KO K08042   adenylate cyclase 2 [EC:4.6.1.1] Organism biu  Bos indicus (zebu cattle) Pathway biu00230   Purine metabolism biu01100   Metabolic pathways biu01522   Endocrine resistance biu04015   Rap1 signaling pathway biu04020   Calcium signaling pathway biu04022   cGMP-PKG signaling pathway biu04024   cAMP signaling pathway biu04062   Chemokine signaling pathway biu04072   Phospholipase D signaling pathway biu04114   Oocyte meiosis biu04211   Longevity regulating pathway biu04213   Longevity regulating pathway - multiple species biu04261   Adrenergic signaling in cardiomyocytes biu04270   Vascular smooth muscle contraction biu04371   Apelin signaling pathway biu04540   Gap junction biu04611   Platelet activation biu04713   Circadian entrainment biu04714   Thermogenesis biu04723   Retrograde endocannabinoid signaling biu04724   Glutamatergic synapse biu04725   Cholinergic synapse biu04727   GABAergic synapse biu04750   Inflammatory mediator regulation of TRP channels biu04911   Insulin secretion biu04912   GnRH signaling pathway biu04913   Ovarian steroidogenesis biu04914   Progesterone-mediated oocyte maturation biu04915   Estrogen signaling pathway biu04916   Melanogenesis biu04918   Thyroid hormone synthesis biu04921   Oxytocin signaling pathway biu04922   Glucagon signaling pathway biu04923   Regulation of lipolysis in adipocytes biu04925   Aldosterone synthesis and secretion biu04926   Relaxin signaling pathway biu04927   Cortisol synthesis and secretion biu04928   Parathyroid hormone synthesis, secretion and action biu04934   Cushing syndrome biu04935   Growth hormone synthesis, secretion and action biu04970   Salivary secretion biu04971   Gastric acid secretion biu04972   Pancreatic secretion biu04976   Bile secretion biu05032   Morphine addiction biu05163   Human cytomegalovirus infection biu05166   Human T-cell leukemia virus 1 infection biu05200   Pathways in cancer biu05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:biu00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     109574822 (ADCY2)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     109574822 (ADCY2)    04371 Apelin signaling pathway     109574822 (ADCY2)    04020 Calcium signaling pathway     109574822 (ADCY2)    04072 Phospholipase D signaling pathway     109574822 (ADCY2)    04024 cAMP signaling pathway     109574822 (ADCY2)    04022 cGMP-PKG signaling pathway     109574822 (ADCY2)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     109574822 (ADCY2)   09144 Cellular community - eukaryotes    04540 Gap junction     109574822 (ADCY2)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     109574822 (ADCY2)    04062 Chemokine signaling pathway     109574822 (ADCY2)   09152 Endocrine system    04911 Insulin secretion     109574822 (ADCY2)    04922 Glucagon signaling pathway     109574822 (ADCY2)    04923 Regulation of lipolysis in adipocytes     109574822 (ADCY2)    04912 GnRH signaling pathway     109574822 (ADCY2)    04913 Ovarian steroidogenesis     109574822 (ADCY2)    04915 Estrogen signaling pathway     109574822 (ADCY2)    04914 Progesterone-mediated oocyte maturation     109574822 (ADCY2)    04921 Oxytocin signaling pathway     109574822 (ADCY2)    04926 Relaxin signaling pathway     109574822 (ADCY2)    04935 Growth hormone synthesis, secretion and action     109574822 (ADCY2)    04918 Thyroid hormone synthesis     109574822 (ADCY2)    04928 Parathyroid hormone synthesis, secretion and action     109574822 (ADCY2)    04916 Melanogenesis     109574822 (ADCY2)    04925 Aldosterone synthesis and secretion     109574822 (ADCY2)    04927 Cortisol synthesis and secretion     109574822 (ADCY2)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     109574822 (ADCY2)    04270 Vascular smooth muscle contraction     109574822 (ADCY2)   09154 Digestive system    04970 Salivary secretion     109574822 (ADCY2)    04971 Gastric acid secretion     109574822 (ADCY2)    04972 Pancreatic secretion     109574822 (ADCY2)    04976 Bile secretion     109574822 (ADCY2)   09156 Nervous system    04724 Glutamatergic synapse     109574822 (ADCY2)    04727 GABAergic synapse     109574822 (ADCY2)    04725 Cholinergic synapse     109574822 (ADCY2)    04723 Retrograde endocannabinoid signaling     109574822 (ADCY2)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     109574822 (ADCY2)   09149 Aging    04211 Longevity regulating pathway     109574822 (ADCY2)    04213 Longevity regulating pathway - multiple species     109574822 (ADCY2)   09159 Environmental adaptation    04713 Circadian entrainment     109574822 (ADCY2)    04714 Thermogenesis     109574822 (ADCY2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     109574822 (ADCY2)   09165 Substance dependence    05032 Morphine addiction     109574822 (ADCY2)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     109574822 (ADCY2)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     109574822 (ADCY2)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     109574822 (ADCY2)    05163 Human cytomegalovirus infection     109574822 (ADCY2)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     109574822 (ADCY2) Enzymes [BR:biu01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      109574822 (ADCY2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc DUF1053 AC_N HNOBA Motif Other DBs NCBI-GeneID:  109574822 NCBI-ProteinID:  XP_019838349 UniProt:  A0A6P5DKR0 LinkDB All DBs Position 20 AA seq 972 aa AA seqDB search MGYLFMCFGGTVSPWDQVSFFLFIIFVVYTMLPFNMRDAIIASVLTSSSHTIVLSVCLSA TPGAKEHLVWQILANVIIFICGNLAGAYHKHLMELALQQTYQDTCNCIKSRIKLEFEKRQ QERLLLSLLPAHIAMEMKAEIIQRLQGPKAGQMENTNNFHNLYVKRHTNVSILYADIVGF TRLASDCSPGELVHMLNELFGKFDQIAKENECMRIKILGDCYYCVSGLPISLPNHAKNCV KMGLDMCEAIKKVRDATGVDINMRVGVHSGNVLCGVIGLQKWQYDVWSHDVTLANHMEAG GVPGRVHISSVTLQHLNGAYKVEEGDGDIRDPYLKQHLVKTYFVINPKGERRSPQHLFRP RHTLDGAKMRASVRMTRYLESWGAAKPFAHLHHRDSMTTENGKISTTDVPMGQHNFQNRT LRTKSQKKRFEEELNERMIQAIDGINAQKQWLKSEDIQRISLLFYNKIIEKEYRATALPA FKYYVTCACLIFFCIFIVQVLVLPKTSILGISFGAAFLSLAFILFVCFAGQLLQCSKKAS ASLLWLLKSSGIIANRPWPRISLTVITTAIILTMAVFNMFFLSDSEETILPTANASNTSL SGASNQAAILRAQNLFFLPYFIYSCILGLISCSVFLRVNYELKMLIMMAALVGYNTIFLH THAPLLDDYSQVLFERPGIWKDLKTMGSVSLFIFFITLLVLGRQNEYYCRLDFLWKNKFK KEREEIETMENLNRVLLENVLPAHVAEHFLARSLKNEELYHQSYDCVCVMFASIPDFKEF YTESDVNKEGLECLRLLNEIIADFDDLLSKPKFSGVEKIKTIGSTYMAATGLSAVPSQEH AQEPERQYMHIGTMVEFAFALVGKLDAINKHSFNDFKLRVGINHGPVIAGVIGAQKPQYD IWGNTVNVASRMDSTGVLDKIQVTEETSIILQTLGYTCTCRGIINVKGKGDLKTYFVNTE MSRSLSQSNLTS NT seq 2919 nt NT seq  +upstreamnt  +downstreamnt atgggctacttgttcatgtgtttcgggggcaccgtctctccctgggaccaggtgtcattc ttcctcttcatcatcttcgtggtgtacaccatgctgcccttcaacatgcgagatgccatc atcgccagtgtcctcacctcctcttctcacaccatcgtgctgagcgtctgcctgtctgca acaccaggggccaaggagcacctggtctggcagatcctggccaacgtgatcatcttcatc tgcgggaacctggcgggggcataccataagcacctcatggagctcgctctgcagcagacg tatcaggacacgtgcaactgcatcaagtcccggatcaagctggaatttgaaaaacgtcag caggagcggctgctgctgtccctgctgccggcacacatagccatggagatgaaagcggag atcatccagaggctgcagggcccmaaagccggccagatggagaacaccaacaacttccac aacctctacgtcaagcggcacaccaacgtcagtatcctctatgcggacattgttgggttc acccgtctggccagtgactgctcccctggagagctcgtccatatgctgaatgaactcttt ggaaagttcgatcaaattgcaaaggagaatgaatgcatgagaataaaaattttaggagac tgctactactgtgtgtccggactgcctatatctctccctaaccatgccaagaattgtgtg aaaatgggactggatatgtgtgaagccataaagaaagtgagggacgccaccggagtggac atcaacatgcgcgtgggagtgcattctgggaacgtgctgtgcggcgtgatcgggctgcag aagtggcagtacgacgtgtggtcacatgacgtcaccctggccaaccacatggaagctgga ggggtccctggacgtgttcacatttcttctgttaccctgcaacacttgaatggagcttac aaagtggaagaaggcgatggtgacatcagagacccgtatttaaagcaacatttggtgaaa acttactttgtaatcaaccccaagggagagcggcggagccctcagcacctctttaggcct cgacacacccttgacggagcgaagatgagggcttctgtccgcatgacccggtacctggag tcctggggggcggccaagccctttgcacacctgcatcacagagacagcatgactacggag aacggcaagatcagcaccacggatgtaccaatgggtcagcataattttcaaaatcgcacc ttaagaaccaagtcacaaaagaaaagatttgaagaggaattaaatgaaaggatgattcaa gcaattgatggaatcaatgcacaaaagcaatggctcaagtcygaagacattcagagaatc tcattgcttttctacaataaaataatagaaaaagaataccgagccaccgcactgccggcc ttcaagtattacgtgacttgcgcttgcctgatcttcttctgcatctttatcgtgcaggtt ctggtcttacccaaaacgtccattctcggratttcctttggagcggcgtttctctcactt gcctttatccttttcgtctgctttgctggacagcttttgcaatgcagcaagaaagcatct gcttctctcctgtggcttttaaagtcatcgggcatcatcgccaaccggccctggcctcgg atctccctgacggtcatcaccacrgccatcatattgaccatggccgtgttcaatatgttt ttcctgagtgactcagaggaaacaattcttccgactgccaacgcgtccaacacaagtctt tctggcgcaagtaaccaggcagcaattctgcgtgcgcaaaatttgtttttcctgccgtac tttatatacagctgcatccttgggctgatctcctgttccgtcttcctgcgtgtgaattac gagctgaagatgctgatcatgatggcagccttggtgggctacaacaccatcttcctccac actcacgctcccctcctggacgactacagccaggtcctgttcgagagaccaggcatttgg aaagacctaaagaccatgggctcagtatctctctttatatttttcatcacactgcttgtt ctgggcagacagaatgaatattactgtaggttagacttcttatggaagaacaagttcaaa aaagagcgggaggagatagaaaccatggagaacttgaaccgagtgctgctggagaacgtg cttcctgcgcacgtggctgagcacttcctggcgcggagcctgaagaacgaggagttatac caccagtcctacgactgcgtctgcgtcatgtttgcctccattcctgatttcaaagaattc tatacagaatcagacgtgaacaaggagggtttggaatgccttcggctcctgaacgagatc attgccgactttgatgatctgctctccaagccgaagttcagtggtgttgaaaagatcaag accatcggcagcacgtacatggcagcgacaggtctgagcgcggtgcccagccaggagcac gcccaggagccggagaggcagtacatgcacattggcaccatggtggagtttgcatttgcc ctggtggggaagctggatgccatcaacaagcactccttcaatgacttcaagttacgagta ggtattaaccatggccctgtcatagccggtgtgattggagctcagaagccgcagtatgac atctggggcaacaccgtcaatgtggccagcaggatggacagcaccggagtcctggacaaa atccaggtgacagaggagacgagcatcatcctacagaccctaggctacacgtgcacgtgt cggggaatcatcaacgtgaaaggaaagggggacctgaagacctacttcgtcaacacggag atgtcacggtccctttctcagagcaacctgacctcctga

Bos indicus (zebu cattle): 109578364 Help Entry 109578364         CDS       T04792                                  Gene name ADCY9 Definition (RefSeq) adenylate cyclase type 9 isoform X1   KO K08049   adenylate cyclase 9 [EC:4.6.1.1] Organism biu  Bos indicus (zebu cattle) Pathway biu00230   Purine metabolism biu01100   Metabolic pathways biu01522   Endocrine resistance biu04015   Rap1 signaling pathway biu04020   Calcium signaling pathway biu04022   cGMP-PKG signaling pathway biu04024   cAMP signaling pathway biu04062   Chemokine signaling pathway biu04072   Phospholipase D signaling pathway biu04114   Oocyte meiosis biu04211   Longevity regulating pathway biu04213   Longevity regulating pathway - multiple species biu04261   Adrenergic signaling in cardiomyocytes biu04270   Vascular smooth muscle contraction biu04371   Apelin signaling pathway biu04540   Gap junction biu04611   Platelet activation biu04713   Circadian entrainment biu04714   Thermogenesis biu04723   Retrograde endocannabinoid signaling biu04724   Glutamatergic synapse biu04725   Cholinergic synapse biu04727   GABAergic synapse biu04750   Inflammatory mediator regulation of TRP channels biu04911   Insulin secretion biu04912   GnRH signaling pathway biu04913   Ovarian steroidogenesis biu04914   Progesterone-mediated oocyte maturation biu04915   Estrogen signaling pathway biu04916   Melanogenesis biu04918   Thyroid hormone synthesis biu04921   Oxytocin signaling pathway biu04923   Regulation of lipolysis in adipocytes biu04925   Aldosterone synthesis and secretion biu04926   Relaxin signaling pathway biu04927   Cortisol synthesis and secretion biu04928   Parathyroid hormone synthesis, secretion and action biu04934   Cushing syndrome biu04935   Growth hormone synthesis, secretion and action biu04961   Endocrine and other factor-regulated calcium reabsorption biu04962   Vasopressin-regulated water reabsorption biu04970   Salivary secretion biu04971   Gastric acid secretion biu04972   Pancreatic secretion biu04976   Bile secretion biu05032   Morphine addiction biu05163   Human cytomegalovirus infection biu05166   Human T-cell leukemia virus 1 infection biu05200   Pathways in cancer biu05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:biu00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     109578364 (ADCY9)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     109578364 (ADCY9)    04371 Apelin signaling pathway     109578364 (ADCY9)    04020 Calcium signaling pathway     109578364 (ADCY9)    04072 Phospholipase D signaling pathway     109578364 (ADCY9)    04024 cAMP signaling pathway     109578364 (ADCY9)    04022 cGMP-PKG signaling pathway     109578364 (ADCY9)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     109578364 (ADCY9)   09144 Cellular community - eukaryotes    04540 Gap junction     109578364 (ADCY9)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     109578364 (ADCY9)    04062 Chemokine signaling pathway     109578364 (ADCY9)   09152 Endocrine system    04911 Insulin secretion     109578364 (ADCY9)    04923 Regulation of lipolysis in adipocytes     109578364 (ADCY9)    04912 GnRH signaling pathway     109578364 (ADCY9)    04913 Ovarian steroidogenesis     109578364 (ADCY9)    04915 Estrogen signaling pathway     109578364 (ADCY9)    04914 Progesterone-mediated oocyte maturation     109578364 (ADCY9)    04921 Oxytocin signaling pathway     109578364 (ADCY9)    04926 Relaxin signaling pathway     109578364 (ADCY9)    04935 Growth hormone synthesis, secretion and action     109578364 (ADCY9)    04918 Thyroid hormone synthesis     109578364 (ADCY9)    04928 Parathyroid hormone synthesis, secretion and action     109578364 (ADCY9)    04916 Melanogenesis     109578364 (ADCY9)    04925 Aldosterone synthesis and secretion     109578364 (ADCY9)    04927 Cortisol synthesis and secretion     109578364 (ADCY9)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     109578364 (ADCY9)    04270 Vascular smooth muscle contraction     109578364 (ADCY9)   09154 Digestive system    04970 Salivary secretion     109578364 (ADCY9)    04971 Gastric acid secretion     109578364 (ADCY9)    04972 Pancreatic secretion     109578364 (ADCY9)    04976 Bile secretion     109578364 (ADCY9)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     109578364 (ADCY9)    04961 Endocrine and other factor-regulated calcium reabsorption     109578364 (ADCY9)   09156 Nervous system    04724 Glutamatergic synapse     109578364 (ADCY9)    04727 GABAergic synapse     109578364 (ADCY9)    04725 Cholinergic synapse     109578364 (ADCY9)    04723 Retrograde endocannabinoid signaling     109578364 (ADCY9)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     109578364 (ADCY9)   09149 Aging    04211 Longevity regulating pathway     109578364 (ADCY9)    04213 Longevity regulating pathway - multiple species     109578364 (ADCY9)   09159 Environmental adaptation    04713 Circadian entrainment     109578364 (ADCY9)    04714 Thermogenesis     109578364 (ADCY9)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     109578364 (ADCY9)   09165 Substance dependence    05032 Morphine addiction     109578364 (ADCY9)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     109578364 (ADCY9)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     109578364 (ADCY9)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     109578364 (ADCY9)    05163 Human cytomegalovirus infection     109578364 (ADCY9)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     109578364 (ADCY9) Enzymes [BR:biu01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      109578364 (ADCY9) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc DUF512 DUF1053 Motif Other DBs NCBI-GeneID:  109578364 NCBI-ProteinID:  XP_019843027 UniProt:  A0A6P5E1J3 LinkDB All DBs Position 25 AA seq 1355 aa AA seqDB search MASPPHQQLLQHHSTEVSCDSSGDSNSVRVRINPKQPSSNSHPKHCKYSISSSCSSSGDS GGVPRRMGAGGRLRRRKKLPQLFERASSRWWDPKFDSVNLEEACMERCFPQTQRRFRYAL FYIGFACLLWSIYFGVHMKSKLIVMVAPALCFLVVCVGFFLFTFTKLYARHYVWTSLVLT LLVFALTLAAQFQVLTPLSGRVDNFNHTRAARPTDTCLSQVGSFSMCIEVLFLLYTVMHL PLYLSLILGVAYSVLFETFGYHFQDEACFASPGAEALHWELLSRALLHLCIHAIGIHLFI MSQVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRIIADDLMKQGDEESENSVKR HATSSPKNRKKKSSIQKAPIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAHALVGLLN DLFGRFDRLCEETKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIRAIEQFCQEK KEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEATAKYLD DRYEMEDGKVTERLGQSVVADQLKGLKTYLIAGQRAKESHCSCSEALLSGFEVLDGSRVS SGPRGQGTASPGSVSDLAQTVKTFDNLKTCPSCGITFTPKPEAGAEGGAVQNGCQEEPKN SAKASGGPSSKTQNGLLSPPPEEKLTNSQTSLCEILQEKGRWAGVSLDQSALLPLRFKNI REKTDAHFVDVIKEDSLMKDYFFKPPINQFSLNFLDPELERAYRTSYQEEQVVKSSPVRT FASATFSSLLDVLLSTTVFLILSITCFLRYGAASTPPPPAALAVFGAALLLEILSLVVSV RMVFFLEDVMTCTKRLLEWIAGWLPRHFIGAILVSLPALAVYSHVTSEFETNIHSTMFTG SAVLTAVVQYCNFCQLSSWMRSSLATVVGAGPLLLLLYVSLCPDSSTVISHLDAVQNFSS TRKLCNASLPHDGRSPASLIGQEVILVFFLLLLLVWFLNREFEVSYRLHYHGDVEADLHR TKIQSMRDQADWLLRNIIPYHVAEQLKVSQTYSKNHDSGGVIFASIVNFSEFYEENYEGG KECYRVLNELIGDFDELLSKPDYSSIEKIKTIGATYMAASGLNATQCRDGSHPQEHLQIL FEFAKEMMRVVDDFNNNMLWFNFKLRVGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMD TTGVECRIQVSEESYRVLSKMGYEFDYRGTVNVKGKGQMKTYLYPKCTDSGLVPQHQLSI SPDIRVQVDGSIGRSPTDEIASLVPSVQNPDQVSPGSENNAQTRDAHPSAKRPWKEPVRA EERCRFGKAIEKSDCEEVGMEEANELTKLNVSERA NT seq 4068 nt NT seq  +upstreamnt  +downstreamnt atggcttccccgccccaccagcagctgctgcagcaccacagcaccgaggtgagctgtgac tccagcggagacagcaacagcgtgcgggtcaggatcaaccccaagcagccgtcctccaac agccacccgaagcactgcaagtacagcatctcctccagctgcagcagctccggggactcc ggaggggtcccccgaagaatgggcgcaggaggccgcctgcgcaggaggaagaagctgccc cagctgttcgaacgggcctccagccggtggtgggaccccaagtttgactctgtgaacctg gaggaggcttgcatggagcgttgcttcccgcagacccagcgccgcttccggtatgcgctc ttctacatcggcttcgcctgccttctctggagcatctattttggggtccacatgaaatcg aaactgattgtcatggtagcccctgctctgtgcttcctcgtggtgtgtgtgggctttttt ctgtttaccttcaccaagttgtacgcccgccattacgtgtggacttcgctggttctcacc ctcctggtattcgccctgaccctggctgcccagtttcaggttttgacgcccctctcagga cgagttgacaacttcaatcatactcgggctgccaggcccacagacacttgcttatctcaa gtggggagcttttccatgtgcatcgaagtgctctttttgctctacaccgtcatgcactta cctttgtacttgagcttgattttgggagtggcctattctgttctttttgagacctttggc taccacttccaagatgaagcctgctttgcctcacctggagcggaggctctgcactgggag ctgctgagccgggccctgctccacctctgcatccacgccatcgggatccacctgttcatc atgtcccaggtgagatccaggagcaccttcctcaaggtgggccagtctattatgcacgga aaggatctggaagtggaaaaggccctgaaagagaggatgattcattctgtgatgccaaga atcatagctgatgacttgatgaaacagggggatgaggagagcgagaattctgtcaaaagg cacgccacctccagccccaagaacaggaagaagaagtcttccatccagaaagcccctatc gccttccgcccgtttaagatgcagcagatcgaagaagtcagtattttatttgcagatatc gtgggcttcaccaagatgagtgccaataagtctgcccacgccctggtgggtctcctcaac gatctgttcggccgctttgaccggttgtgtgaggagaccaaatgtgagaaaatcagcacc ttgggagactgctactattgtgtggctgggtgtcctgagccaagggccgaccatgcctac tgctgcatcgagatggggttgggcatgataagagccattgagcagttctgccaagagaag aaagagatggtgaacatgcgcgttggggttcacacagggaccgtcctgtgtggcatcttg ggcatgaggaggtttaaatttgacgtgtggtccaatgatgtgaacttggccaatctcatg gagcagctgggagtggctggcaaggttcacatttccgaggccactgcaaaatacctagat gaccggtacgaaatggaggatgggaaagttactgaacgccttggccagagtgttgttgct gaccagttgaaaggtttgaagacatacctgatagcgggtcagagagcgaaggagtctcac tgcagctgttcagaggccttactttctggctttgaggtccttgacggctcgcgggtgtcc tcaggccctaggggacaggggacagcgtcgccagggagtgtcagtgacttggcgcagact gtcaaaacctttgataaccttaagacctgcccatcgtgyggaatcacgttcactcccaag ccagaagctggtgcagaaggtggagcggtccagaacggctgtcaggaggagcccaagaac agtgccaaggcctccggaggacccagctccaaaacgcaaaatggacttctgagtcctccc ccggaggagaagctcaccaacagtcagacctccctgtgcgagatcttacaggagaagggc aggtgggcaggcgtgagcctggatcagtcagctctccttccgctgaggttcaagaacatc cgggagaaaacggatgcccactttgttgacgttatcaaggaagacagcctgatgaaagac tacttttttaagccgcccattaaccagttcagcttgaacttcctggatccggagctcgag cgggcctacaggaccagctatcaagaagagcaggttgtaaagagctctcccgtgaggact ttcgccagtgccaccttcagctccctcctggatgtgcttctgtcgacaacagtgtttctg attctctccatcacctgcttcctgaggtacggggccgcctccacgccgcccccgccggcc gccctggcagtcttcggagcggccctgctgctggagatcctgtccctcgtggtctctgtc aggatggtgttcttcctggaggacgtgatgacgtgcacgaagcgcctgctggagtggata gccggctggctcccgcgccatttcatcggggccatcctggtgtctctccccgccctggcg gtgtattcacacgtcacctctgaatttgaracaaacatacactccaccatgttcacgggc tcggccgtgctgaccgccgtggtgcaatactgcaacttctgccagctcagctcctggatg cggtcctccctggccactgtcgtcggggccgggcccctgctgctgctgctctacgtctcc ctgtgcccggacagttccactgtaatttcacaccttgatgcagtacagaatttcagctcc accaggaagctgtgcaacgcctcgctgcctcacgacggcaggagcccagccagcctgatc ggccaggaggtgattctcgtcttcttcctcctgctcctgttggtctggttcctgaaccga gagttcgaagtcagctaccgcctgcactaccatggggacgtggaggcggacctgcaccgc accaagatccagagcatgagggaccaggccgactggctgctgcggaacatcatcccctac cacgtggccgagcagctcaaggtgtcccagacctactccaagaaccacgacagcggaggc gtcatcttcgccagcatcgtcaacttcagcgagttctacgaggagaactacgagggcggc aaggagtgctacagggtcctcaacgagctgatcggggactttgacgagctcctgagcaag ccggactacagcagcatcgagaagatcaagaccatcggggccacgtacatggccgcgtcc gggctgaacgccacgcagtgccgcgacggcagccacccgcaggagcacctgcagatcctc ttcgagttcgccaaggagatgatgcgtgtggtggacgacttcaacaacaacatgctgtgg ttcaacttcaagctcagggtgggcttcaaccacgggcccctgacggcgggcgtcatcggc accaccaagctgctgtacgacatctggggggacacggtcaacatcgccagcaggatggac accacgggggtggagtgccgcatccaggtcagcgaggagagctaccgcgtcctgagcaag atgggctacgagttcgactaccgagggacggtgaacgtcaagggcaaaggccaaatgaag acctacctgtaccccaagtgcacagacagtgggttggtgccacagcaccagctgtccatc tcacccgacatccgggtccaggtggatggcagcatcggacgctcccccacagacgagata gccagcctggtgccttccgttcagaacccggaccaggtgtccccaggttccgagaacaac gcccagaccagggacgctcacccgtctgctaagagaccctggaaggagccagtcagagcc gaggaaaggtgtcggttcggcaaagccatagagaaaagcgactgtgaagaagtggggatg gaggaagccaacgaactcacgaagctcaacgtctcagagagggcgtga

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