Bos indicus (zebu cattle): 109558077 Help Entry 109558077         CDS       T04792                                  Gene name IL6 Definition (RefSeq) interleukin-6   KO K05405   interleukin 6 Organism biu  Bos indicus (zebu cattle) Pathway biu01521   EGFR tyrosine kinase inhibitor resistance biu01523   Antifolate resistance biu04060   Cytokine-cytokine receptor interaction biu04061   Viral protein interaction with cytokine and cytokine receptor biu04066   HIF-1 signaling pathway biu04068   FoxO signaling pathway biu04151   PI3K-Akt signaling pathway biu04218   Cellular senescence biu04620   Toll-like receptor signaling pathway biu04621   NOD-like receptor signaling pathway biu04623   Cytosolic DNA-sensing pathway biu04625   C-type lectin receptor signaling pathway biu04630   JAK-STAT signaling pathway biu04640   Hematopoietic cell lineage biu04657   IL-17 signaling pathway biu04659   Th17 cell differentiation biu04668   TNF signaling pathway biu04672   Intestinal immune network for IgA production biu04931   Insulin resistance biu04932   Non-alcoholic fatty liver disease biu04933   AGE-RAGE signaling pathway in diabetic complications biu05010   Alzheimer disease biu05020   Prion disease biu05022   Pathways of neurodegeneration - multiple diseases biu05132   Salmonella infection biu05133   Pertussis biu05134   Legionellosis biu05135   Yersinia infection biu05142   Chagas disease biu05143   African trypanosomiasis biu05144   Malaria biu05146   Amoebiasis biu05152   Tuberculosis biu05161   Hepatitis B biu05162   Measles biu05163   Human cytomegalovirus infection biu05164   Influenza A biu05166   Human T-cell leukemia virus 1 infection biu05167   Kaposi sarcoma-associated herpesvirus infection biu05168   Herpes simplex virus 1 infection biu05169   Epstein-Barr virus infection biu05171   Coronavirus disease - COVID-19 biu05200   Pathways in cancer biu05202   Transcriptional misregulation in cancer biu05321   Inflammatory bowel disease biu05323   Rheumatoid arthritis biu05332   Graft-versus-host disease biu05410   Hypertrophic cardiomyopathy Brite KEGG Orthology (KO) [BR:biu00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     109558077 (IL6)    04668 TNF signaling pathway     109558077 (IL6)    04066 HIF-1 signaling pathway     109558077 (IL6)    04068 FoxO signaling pathway     109558077 (IL6)    04151 PI3K-Akt signaling pathway     109558077 (IL6)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     109558077 (IL6)    04061 Viral protein interaction with cytokine and cytokine receptor     109558077 (IL6)  09140 Cellular Processes   09143 Cell growth and death    04218 Cellular senescence     109558077 (IL6)  09150 Organismal Systems   09151 Immune system    04640 Hematopoietic cell lineage     109558077 (IL6)    04620 Toll-like receptor signaling pathway     109558077 (IL6)    04621 NOD-like receptor signaling pathway     109558077 (IL6)    04623 Cytosolic DNA-sensing pathway     109558077 (IL6)    04625 C-type lectin receptor signaling pathway     109558077 (IL6)    04659 Th17 cell differentiation     109558077 (IL6)    04657 IL-17 signaling pathway     109558077 (IL6)    04672 Intestinal immune network for IgA production     109558077 (IL6)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     109558077 (IL6)    05202 Transcriptional misregulation in cancer     109558077 (IL6)   09163 Immune disease    05323 Rheumatoid arthritis     109558077 (IL6)    05321 Inflammatory bowel disease     109558077 (IL6)    05332 Graft-versus-host disease     109558077 (IL6)   09164 Neurodegenerative disease    05010 Alzheimer disease     109558077 (IL6)    05020 Prion disease     109558077 (IL6)    05022 Pathways of neurodegeneration - multiple diseases     109558077 (IL6)   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     109558077 (IL6)   09167 Endocrine and metabolic disease    04932 Non-alcoholic fatty liver disease     109558077 (IL6)    04931 Insulin resistance     109558077 (IL6)    04933 AGE-RAGE signaling pathway in diabetic complications     109558077 (IL6)   09171 Infectious disease: bacterial    05132 Salmonella infection     109558077 (IL6)    05135 Yersinia infection     109558077 (IL6)    05133 Pertussis     109558077 (IL6)    05134 Legionellosis     109558077 (IL6)    05152 Tuberculosis     109558077 (IL6)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     109558077 (IL6)    05161 Hepatitis B     109558077 (IL6)    05171 Coronavirus disease - COVID-19     109558077 (IL6)    05164 Influenza A     109558077 (IL6)    05162 Measles     109558077 (IL6)    05168 Herpes simplex virus 1 infection     109558077 (IL6)    05163 Human cytomegalovirus infection     109558077 (IL6)    05167 Kaposi sarcoma-associated herpesvirus infection     109558077 (IL6)    05169 Epstein-Barr virus infection     109558077 (IL6)   09174 Infectious disease: parasitic    05146 Amoebiasis     109558077 (IL6)    05144 Malaria     109558077 (IL6)    05142 Chagas disease     109558077 (IL6)    05143 African trypanosomiasis     109558077 (IL6)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     109558077 (IL6)    01523 Antifolate resistance     109558077 (IL6)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:biu04052]     109558077 (IL6) Cytokines and growth factors [BR:biu04052]  Cytokines   Interleukins    109558077 (IL6) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IL6 MAP65_ASE1 IL23 GCSF ADIP Lipoprotein_6 ZapB Motif Other DBs NCBI-GeneID:  109558077 NCBI-ProteinID:  XP_019815115 UniProt:  A0A6P5BRN2 LinkDB All DBs Position 4 AA seq 187 aa AA seqDB search MTSAFPTPGPLGEDFKNDTTPGRLLLTTPEKTEALIKRMVDKISAMRKEICEKNDECESS KETLAENKLNLPKMEEKDGCFQSGFNQAICLIRTTAGLLEYQIYLDYLQNEYEGNQENVR DLRKNIRTLIQILKQKIADLITTPATNTDLLEKMQSSNEWVKNAKIILILRNLENFLQFS LRAIRMK NT seq 564 nt NT seq  +upstreamnt  +downstreamnt atgacttctgctttccctaccccgggtcccctgggagaagatttcaaaaatgacaccacc ccaggcagactacttctgaccactccagagaaaaccgaagctctcattaagcgcatggtc gacaaaatctctgcaatgagaaaggagatatgtgagaagaatgatgagtgtgaaagcagc aaggagacactggcagaaaataagctgaatcttccaaaaatggaggaaaaggacggatgc ttccaatctgggttcaatcaggcgatttgcttgatcagaaccactgctggtcttctggag tatcagatatacctggactacctccagaacgagtatgagggaaatcaggaaaatgtcagg gatttgaggaaaaatatcagaacactgatccagatcctgaagcaaaagatcgcagatcta ataaccactccagccacaaacactgacctgctggagaagatgcagtcttcaaacgagtgg gtaaagaacgcaaagattatcctcatcctgagaaaccttgagaatttcctgcagttcagc ctgagagctattcggatgaagtag

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