Bos indicus (zebu cattle): 109561587
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Entry
109561587 CDS
T04792
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
biu
Bos indicus (zebu cattle)
Pathway
biu04217
Necroptosis
biu04380
Osteoclast differentiation
biu04620
Toll-like receptor signaling pathway
biu04621
NOD-like receptor signaling pathway
biu04630
JAK-STAT signaling pathway
biu04658
Th1 and Th2 cell differentiation
biu04659
Th17 cell differentiation
biu05145
Toxoplasmosis
biu05160
Hepatitis C
biu05161
Hepatitis B
biu05162
Measles
biu05164
Influenza A
biu05165
Human papillomavirus infection
biu05167
Kaposi sarcoma-associated herpesvirus infection
biu05168
Herpes simplex virus 1 infection
biu05169
Epstein-Barr virus infection
biu05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
biu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
109561587 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
109561587 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
109561587 (TYK2)
04621 NOD-like receptor signaling pathway
109561587 (TYK2)
04658 Th1 and Th2 cell differentiation
109561587 (TYK2)
04659 Th17 cell differentiation
109561587 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
109561587 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
109561587 (TYK2)
05160 Hepatitis C
109561587 (TYK2)
05171 Coronavirus disease - COVID-19
109561587 (TYK2)
05164 Influenza A
109561587 (TYK2)
05162 Measles
109561587 (TYK2)
05168 Herpes simplex virus 1 infection
109561587 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
109561587 (TYK2)
05169 Epstein-Barr virus infection
109561587 (TYK2)
05165 Human papillomavirus infection
109561587 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
109561587 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
biu01001
]
109561587 (TYK2)
Enzymes [BR:
biu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
109561587 (TYK2)
Protein kinases [BR:
biu01001
]
Non-receptor tyrosine kinases
JAK family [OT]
109561587 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
Kinase-like
Kdo
ABC1
FERM_C_FAK1
Motif
Other DBs
NCBI-GeneID:
109561587
NCBI-ProteinID:
XP_019819701
UniProt:
A0A6P5C255
LinkDB
All DBs
Position
7:complement(13339128..13368819)
Genome browser
AA seq
1187 aa
AA seq
DB search
MPLCQWRATTRGRKPSGDGAQPMATREGLKVLLHWAGPSGGEPWVTFTEPTLTAEDVCIH
VXHKVGITPPCFNLFALFDAQAQVWLPPNHILDTSRDSSLTLYFRMRFYFRNWHGTNPQE
PAVYRCGPPGAETSSEQAEQGVQLLDPASFEYLFEQGKHEFVNDVASLWELSSEEEIHHF
QNESLGMALLHLCHLALRNGVPLEKVAKKTSFKDCIPRSFRRQMRQHNALTRLRQRSIFR
KFLRAFQPGCLSQQVVMVKYLATLERLAPRFGTERVPVCHLELLSQADGEPCYIREGGQA
PPDPGSESAAGPPTHEVLVSGTEGIRWRLVPAEGPADGGAGGGSRMPDADPSGKKMKAEE
VGSEPVDRPRESPWSYFCDFQDITHMVLKERHVSIHCQDNKCLELTLPXXXXALSLVSLV
DGYFRLTADSNHYLCHEVAPPRLVMSIQDGIHGPLLEPFVLAKLKPEAGLYLIHWSTSHL
HRLILTVAQRDQLQAPGTKGLRLRKFPIELQAGTVMLEGWGRSFPSVRDLRAALQDCSLR
AGNDCFSLRRCCLPRPGEISNLIVTRGPQASTRPLNLSHLSFYRVRQEDITQLSHLGQGT
RTNVYEGLLRVGGGGPEEDKADGEEPPTPXGDRGQELRVVLKVLDPSHHDIALAFYETAS
LMSQVSHVHLAFVHGVFVHGSENIMVTEYVEHGPLDVWLRRERGRVPLAWKLAVAQQLAS
ALSYLEDKSLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLSALSREERVERIPWTA
PECLSGGANSLSTAADKWGFGATLLEICFDGEAPLQGRSPSEKERFYQKQHKLPEPSCPE
LATLTSQCLTYEPAQRPSFRTILRDFTQLQPQNLADVLSVSPDSLASDPTVFHKRYLKKI
RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAGCGPQLRTGWRREIDILRKLYHKHIV
KYKGCCEDQGEKSIQLVMEYMPLGSLRDYLPRHNVGLVQLLLFSLQICEGMAYLHSQHYV
HRDLAARNVLLDNNRLVKIGDFGLTKAVPEGHEYYCVREDGDSPVFWYAPECLKECKFYY
ASDVWSFGVLMYELLTYCDSSQSPPSKFIELIGLTQGQMTVLRLTELLERGERLPQPEKC
PSEIYCLMKDCWKAEASFRPTFQNLVPILRSYHEKYQGQAPSVFSVC
NT seq
3564 nt
NT seq
+upstream
nt +downstream
nt
atgcctctgtgccaatggagggccaccaccaggggcaggaagcccagtggggacggagct
cagcccatggccaccagagaaggcctgaaagtgcttctgcactgggctggccccagtggt
ggggagccctgggtcaccttcactgagcccacactgaccgcggaggatgtctgcatccac
gtcgyacacaaagtcggcatcactccaccctgcttcaatctttttgccctcttcgatgcc
caggcccaggtctggctgcctccaaatcacattctggatacctccagggactccagcctg
acgctgtacttccgcatgaggttttatttccgaaactggcatggcacgaatcctcaggag
ccagctgtgtaccgctgcgggcccccaggggccgagacttcctcagaacaggcagagcag
ggggtgcaactcctggaccctgcctcctttgagtacctctttgagcagggcaagcatgaa
tttgtaaatgacgtggcatcactatgggagctatccagcgaggaggagatccaccacttt
cagaatgagagcctgggcatggcccttttgcacctctgccacctcgctctccgcaatggt
gtcccccttgaaaaggtggcgaagaaaaccagcttcaaggattgcatcccacgctccttc
cggcggcagatgcggcagcacaacgctctgacacggctgcgccaacggagcatcttccgc
aagttcctgcgggccttccagccgggctgcctctcccagcaggtcgtcatggtgaagtac
ctggccacgctcgagcgactggcaccccgctttggcacagagcgtgtgcccgtgtgccac
ctggagctgctgtcccaagctgacggggagccctgctacatccgggagggtgggcaggcc
cctcctgaccccgggtctgagtctgctgccggaccccccacccacgaggtgctggtgtca
ggcacggaaggcatccggtggcggctggtaccggcggaggggcctgctgatggcggtgct
ggtggcggcagcaggatgcctgatgctgacccatctgggaagaaaatgaaggccgaggag
gtgggcagcgagccagtggacaggcctcgggagagcccctggtcctacttctgtgacttc
caggacatcacccacatggtgctgaaggaacgccacgtcagcatccattgtcaggacaac
aagtgcctggagctgaccctgccttnnnnnnnnnnggccctgtccttggtgtcgctggtg
gatggctacttccgcctgaccgccgactcaaaccactacctgtgccacgaggtggctcct
ccacggctggtgatgagtatccaggatggcatccacggccccctgctggagccatttgtg
ctggccaagctgaagcccgaggctggcctctaccttatccactggagcaccagccacctc
caccgcctcatcctcacagtggcccagcgcgaccagctgcaggctccaggcactaagggc
ttgcgcctgcggaagttccctatcgagctccaggccgggacagtcatgctggagggctgg
ggccggtctttccccagcgtgcgggacctgagggctgccctgcaggactgctcgctgcgg
gccggcaacgactgcttttccctgcgtcgctgctgcctgccccggcccggagagatctcc
aacctcatcgtcacacgggggcctcaggccagcaccagaccgctcaacctcagtcatctc
agcttctaccgagtccgccaggaagacatcacccagctgtcccacttgggccagggcaca
aggaccaacgtgtatgagggcctcttgcgagtggggggcggaggccccgaggaggacaag
gcagatggcgaggaaccccccacgcccgytggggaccgtgggcaggagctgcgtgtggtg
ctcaaggtgctagaccccagtcaccacgacatcgccctggccttctacgagacagccagc
ctcatgagccaggtctcccacgtgcacctggccttcgtgcacggcgtcttcgtgcacggc
tccgagaacatcatggtgaccgagtacgtggagcacgggcccctggacgtatggctgcgg
cgggagaggggccgcgtgcccctggcctggaagttggcagtggcccagcagctggccagc
gccctcagttacctggaagacaaaagcctggttcatggcaacgtgtgtggccggaacatc
ctgctggcacggctggggctggcggagggcaccagccccttcatcaagctgagtgacccc
ggcgtgggcctgagtgccctctccagggaggagcgggtggagcggatcccctggacagcc
cccgagtgcctgtctggtggagccaacagcctgagcaccgcagccgacaagtggggcttt
ggtgccaccctcctggagatctgcttcgacggcgaggcccccctgcagggccgtagtccc
tctgagaaagagcgcttctaccagaagcagcacaaactgcctgagccctcgtgcccagag
ctggccacactcaccagccagtgcctgacctacgagccagcccagcggccatccttccgc
accatcctgcgtgacttcactcagctacagccccagaatctcgctgatgtcttgtctgtg
agcccggattcactggcttcagatcccacggttttccacaagcgatacttgaaaaagatc
cgggatctgggtgagggtcacttcggaaaggtcagcctgtattgctacgaccccaccaac
gacggcactggtgagatggtagccgtgaaggccctcaaggcaggctgcggtccccagctc
cggacgggctggaggcgagaaatcgacatcctacgcaagctctaccacaagcacatcgtc
aagtacaagggctgctgcgaggaccaaggcgagaagtcgatacagctggtcatggaatac
atgcccctgggcagcctccgagactacttgccccggcacaatgtcgggctggtccagctg
ctgctcttctccctgcagatctgcgagggtatggcctacctgcactcacagcactacgtg
catcgagacctggctgcgcgcaacgtgctgctggacaacaacaggctagtcaagatcggg
gacttcggcctcaccaaggccgtgcccgaaggccacgagtattactgtgtgcgcgaggat
ggggacagtcctgtgttctggtatgccccggagtgcctgaaggagtgtaagttctactat
gcatcagacgtctggtcctttggggtcctcatgtatgagctgctgacctactgtgactcc
agccagagccctccctcgaaattcatcgagctcataggcctcacccaagggcagatgact
gtgctgaggctcacagagctgctggaacgaggggagaggctgccacaaccagagaaatgc
ccctctgagatctattgcctcatgaaggactgctggaaggcagaggcctcattccgcccg
accttccagaacctcgtacccatcctcagatcataccacgagaaataccaaggccaggcc
ccctcggtgttcagtgtctgctga
DBGET
integrated database retrieval system
