Bos indicus (zebu cattle): 109563078 Help Entry 109563078         CDS       T04792                                  Gene name TGFBR1 Definition (RefSeq) TGF-beta receptor type-1   KO K04674   TGF-beta receptor type-1 [EC:2.7.11.30] Organism biu  Bos indicus (zebu cattle) Pathway biu04010   MAPK signaling pathway biu04060   Cytokine-cytokine receptor interaction biu04068   FoxO signaling pathway biu04144   Endocytosis biu04218   Cellular senescence biu04350   TGF-beta signaling pathway biu04371   Apelin signaling pathway biu04380   Osteoclast differentiation biu04390   Hippo signaling pathway biu04520   Adherens junction biu04659   Th17 cell differentiation biu04926   Relaxin signaling pathway biu04933   AGE-RAGE signaling pathway in diabetic complications biu05142   Chagas disease biu05161   Hepatitis B biu05166   Human T-cell leukemia virus 1 infection biu05200   Pathways in cancer biu05210   Colorectal cancer biu05212   Pancreatic cancer biu05220   Chronic myeloid leukemia biu05225   Hepatocellular carcinoma biu05226   Gastric cancer Brite KEGG Orthology (KO) [BR:biu00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     109563078 (TGFBR1)    04350 TGF-beta signaling pathway     109563078 (TGFBR1)    04390 Hippo signaling pathway     109563078 (TGFBR1)    04371 Apelin signaling pathway     109563078 (TGFBR1)    04068 FoxO signaling pathway     109563078 (TGFBR1)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     109563078 (TGFBR1)  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     109563078 (TGFBR1)   09143 Cell growth and death    04218 Cellular senescence     109563078 (TGFBR1)   09144 Cellular community - eukaryotes    04520 Adherens junction     109563078 (TGFBR1)  09150 Organismal Systems   09151 Immune system    04659 Th17 cell differentiation     109563078 (TGFBR1)   09152 Endocrine system    04926 Relaxin signaling pathway     109563078 (TGFBR1)   09158 Development and regeneration    04380 Osteoclast differentiation     109563078 (TGFBR1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     109563078 (TGFBR1)   09162 Cancer: specific types    05210 Colorectal cancer     109563078 (TGFBR1)    05212 Pancreatic cancer     109563078 (TGFBR1)    05225 Hepatocellular carcinoma     109563078 (TGFBR1)    05226 Gastric cancer     109563078 (TGFBR1)    05220 Chronic myeloid leukemia     109563078 (TGFBR1)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     109563078 (TGFBR1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     109563078 (TGFBR1)    05161 Hepatitis B     109563078 (TGFBR1)   09174 Infectious disease: parasitic    05142 Chagas disease     109563078 (TGFBR1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:biu01001]     109563078 (TGFBR1) Enzymes [BR:biu01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.30  receptor protein serine/threonine kinase      109563078 (TGFBR1) Protein kinases [BR:biu01001]  Receptor serine/threonine kinases (RSTK): TKL group   TGFBR1 family [OT]    109563078 (TGFBR1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr TGF_beta_GS Activin_recp Pkinase_fungal APH FTA2 Motif Other DBs NCBI-GeneID:  109563078 NCBI-ProteinID:  XP_019821829 UniProt:  A0A6P5C8J3 LinkDB All DBs Position 8 AA seq 499 aa AA seqDB search MXXXXATPRPRLFLLMLAAAATLVPEATPLQCFCHLCTKDNFTCVTDGLCFVSVTETTDK VIHNSMCIAEIDLIPRDRPFVCAPSSKTGSITTTYCCNQDHCNKIELPTVGKPSSGLGPV ELAAVIAGPVCFVCISLMLMVYICHNRTVIHHRVPNEEDPSLDRPFISEGTTLKDLIYDM TTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFR EAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIK LALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDT IDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEVARRCSIGGIHEDY QLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLT ALRIKKTLSQLSQQEGIKM NT seq 1500 nt NT seq  +upstreamnt  +downstreamnt atggnnnnnnnnnnngctactccgcgtccccggctgttcctcctcatgctggcggcggcg gccacgctggtcccggaggcaacgccattacagtgtttctgccacctttgtacaaaagac aattttacttgtgtcacagatgggctttgctttgtctctgtcacagagaccacagacaaa gttatacataatagcatgtgtatagctgaaattgacctaattccacgagacaggccattt gtatgtgcaccatcttcaaaaactgggtctataactacaacatattgctgcaaccaggac cactgcaataaaatagaacttccaactgttggaaagccatcatctggccttggtcctgtt gaactggcagctgtcattgctggaccagtctgctttgtctgtatctcactcatgttgatg gtctatatttgccataaccgcactgtcattcaccatcgagtgccaaatgaagaggatccc tcgttagatcgcccttttatttcagagggtacaacgttaaaagatttaatttacgacatg acaacatcaggttctggatcaggtttaccattgcttgttcagagaacaattgcgagaact attgtgttacaagaaagtattggcaaaggtcgttttggagaagtttggcgaggaaaatgg agaggagaagaagttgctgttaaaatattctcctctagagaagaacgttcatggttccgt gaagcagagatttatcagactgtcatgttacgtcacgaaaacatcttgggatttatagca gcagacaataaagacaatggcacatggactcagctctggttggtgtcagattatcatgag cayggatccctttttgattatttgaacagatacacagttactgtggaaggaatgataaaa cttgctctgtccacagcaagtggacttgcccatcttcacatggagatagttggtacccaa ggaaaaccagccatagctcatagggatttgaaatcaaagaatatcttggtaaagaagaat ggaacttgctgtattgcagacttaggattggcagtaaggcatgattcggccacggataca attgacattgctccaaaccacagagtgggaacaaaaaggtacatggcccctgaagttcta gatgattccataaatatgaaacactttgaatccttcaaacgtgctgacatctatgcaatg ggactagtattctgggaagtagctcgacgatgttccattggtggaatacatgaagattac cagctgccttattatgatcttgtaccttccgatccatcagttgaagaaatgagaaaagtt gtttgtgaacagaagttaaggccaaatattccaaacagatggcagagctgtgaagccttg agagtaatggctaaaattatgagagaatgttggtatgccaatggagcagctaggcttaca gctttgcggattaagaaaacattgtcacaactcagtcagcaggaaggcatcaaaatgtaa

Bos indicus (zebu cattle): 109576148 Help Entry 109576148         CDS       T04792                                  Gene name TGFBR2 Definition (RefSeq) TGF-beta receptor type-2   KO K04388   TGF-beta receptor type-2 [EC:2.7.11.30] Organism biu  Bos indicus (zebu cattle) Pathway biu04010   MAPK signaling pathway biu04060   Cytokine-cytokine receptor interaction biu04068   FoxO signaling pathway biu04144   Endocytosis biu04218   Cellular senescence biu04350   TGF-beta signaling pathway biu04380   Osteoclast differentiation biu04390   Hippo signaling pathway biu04520   Adherens junction biu04659   Th17 cell differentiation biu04926   Relaxin signaling pathway biu04933   AGE-RAGE signaling pathway in diabetic complications biu05142   Chagas disease biu05161   Hepatitis B biu05166   Human T-cell leukemia virus 1 infection biu05200   Pathways in cancer biu05202   Transcriptional misregulation in cancer biu05210   Colorectal cancer biu05212   Pancreatic cancer biu05220   Chronic myeloid leukemia biu05225   Hepatocellular carcinoma biu05226   Gastric cancer Brite KEGG Orthology (KO) [BR:biu00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     109576148 (TGFBR2)    04350 TGF-beta signaling pathway     109576148 (TGFBR2)    04390 Hippo signaling pathway     109576148 (TGFBR2)    04068 FoxO signaling pathway     109576148 (TGFBR2)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     109576148 (TGFBR2)  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     109576148 (TGFBR2)   09143 Cell growth and death    04218 Cellular senescence     109576148 (TGFBR2)   09144 Cellular community - eukaryotes    04520 Adherens junction     109576148 (TGFBR2)  09150 Organismal Systems   09151 Immune system    04659 Th17 cell differentiation     109576148 (TGFBR2)   09152 Endocrine system    04926 Relaxin signaling pathway     109576148 (TGFBR2)   09158 Development and regeneration    04380 Osteoclast differentiation     109576148 (TGFBR2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     109576148 (TGFBR2)    05202 Transcriptional misregulation in cancer     109576148 (TGFBR2)   09162 Cancer: specific types    05210 Colorectal cancer     109576148 (TGFBR2)    05212 Pancreatic cancer     109576148 (TGFBR2)    05225 Hepatocellular carcinoma     109576148 (TGFBR2)    05226 Gastric cancer     109576148 (TGFBR2)    05220 Chronic myeloid leukemia     109576148 (TGFBR2)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     109576148 (TGFBR2)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     109576148 (TGFBR2)    05161 Hepatitis B     109576148 (TGFBR2)   09174 Infectious disease: parasitic    05142 Chagas disease     109576148 (TGFBR2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:biu01001]     109576148 (TGFBR2) Enzymes [BR:biu01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.30  receptor protein serine/threonine kinase      109576148 (TGFBR2) Protein kinases [BR:biu01001]  Receptor serine/threonine kinases (RSTK): TKL group   TGFBR2 family [OT]    109576148 (TGFBR2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  ecTbetaR2 PK_Tyr_Ser-Thr Pkinase Pkinase_fungal APH Motif Other DBs NCBI-GeneID:  109576148 NCBI-ProteinID:  XP_019840141 UniProt:  A0A6P5DPP1 LinkDB All DBs Position 22 AA seq 567 aa AA seqDB search MGRGLLGGLWPLHVVLWTRIASTIPPHVPKSVNSDMMVTDHNGAIKLSQLCKFCDVRSST CDNQKSCWSNCSITAICEKPEEVCVAVWRKNDENITLETVCHDPKIAYHGFVLDDAASSK CIMKERKGSGETFFMCSCSSEECNDHIIFSEEYTSSNPDLLLVIFQVTGVSLLPPLGIAI AVIITFYCYRIHRQQKLSPAWDSGKPRKLMEFSEHLAIILEDDRSDISSTCANNINHNTE LXPIELDTLVGKGRFAEVYKAKLKQNTSEQFETVAVKIFPYEEYASWKTEKDIFSDINLK HENILQFLTAEERKTELGKQYWLITAFHAKGNLQEYLTRHVISWEDLRRLGGSLARGIAH LHSDHTLCGRPKMPIVHRDLKSSNILVKGDLTCCLCDFGLSLRLDPTLSVDDLANSGQVG TARYMAPEVLESRMNLENVESFKQTDVYSMALVLWEMTSRCNAVGEVKDYEPPFGSKVRE HPCVESMKDNVLRDRGRPEIPSSWLNHQGIQTVCETLAECWDHDPEARLTAQCVAERFSE LEHLDRLSGRSSSEEKIPEDGSLNTTK NT seq 1704 nt NT seq  +upstreamnt  +downstreamnt atgggccgggggctgctcgggggcctgtggccgctgcacgtcgtcctgtggacgcgcatc gccagcacgatcccgccgcacgttcccaagtcggttaacagcgatatgatggtcactgac cacaacggygccatcaagctgtcrcagctgtgtaagttctgcgacgtgcggtcgtccacc tgtgacaaccagaagtcctgctggagcaactgcagcatcacggccatctgcgagaagccg gaggaggtctgcgtggctgtctggaggaagaatgatgagaacatcacgctggagacagtc tgccacgaccccaagattgcctaccatggatttgtcctggacgatgctgcttcttcaaag tgtatcatgaaggaaagaaaggggtccggagagactttcttcatgtgctcctgcagctcc gaagagtgcaatgaccacatyatcttctccgaagagtacaccagcagtaaccccgacttg ctgctggttatcttccaagtgacaggcgtcagcctcctgccaccgctgggcatcgccatc gcagtcatcatcactttctactgctaccgcatccaccggcagcagaagctgagcccagcc tgggactcgggcaagccgcgcaagctgatggagttcagtgagcacctggccatcatcctg gaggacgaccgctccgacatcagctccacctgygccaacaacatcaaccacaacacggag ctgcygcccatcgagctggacaccctggtgggcaaggggcgcttcgccgaggtctacaag gccaagctgaagcagaacacgtctgagcagttcgagaccgtggccgtcaagatcttcccc tacgaggagtatgcctcctggaagacggagaaggacatcttctcggacatcaacctcaag cacgagaacatcctgcagttcctgacggccgaggagcgcaagacggagctgggcaagcag tactggctcatcactgccttccacgccaagggcaacctgcaggagtacctgacgcgccac gtcatcagctgggaggacctgcgccggctgggcggctcgctggcccgcggcatcgcgcac ctgcacagcgaccacaccctgtgcggccggcccaagatgcccatcgtgcacagggacctc aagagctccaacatcctggtcaagggcgacctcacctgctgcctctgcgacttcgggctc tcactgcggctggaccccaccctgtcagtggatgacctggccaacagtgggcaggtggga acggcgagatacatggctccagaggtcctcgagtccaggatgaatctggagaacgtggag tccttcaagcagacggatgtctactccatggccctggtgctctgggagatgacgtctcgc tgcaacgcagtgggagaagtgaaggactatgagcctccgttcgggtctaaggtgcgggag catccctgtgtggaaagcatgaaggacaacgtgctgagagatcgaggccgaccagagatt cccagctcctggctcaaccaccagggcatccagacggtgtgcgagacrctggccgaatgc tgggaccatgaccccgaggcccggctcacggcgcagtgcgtggccgagcgcttcagygag ctggagcacctggacaggctctccgggaggagcagctcggaggagaagatccccgaagat ggctccctcaacactaccaaatag

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