Bos indicus (zebu cattle): 109574822 Help Entry 109574822         CDS       T04792                                  Symbol ADCY2 Name (RefSeq) adenylate cyclase type 2   KO K08042   adenylate cyclase 2 [EC:4.6.1.1] Organism biu  Bos indicus (zebu cattle) Pathway biu00230   Purine metabolism biu01100   Metabolic pathways biu01522   Endocrine resistance biu04015   Rap1 signaling pathway biu04020   Calcium signaling pathway biu04022   cGMP-PKG signaling pathway biu04024   cAMP signaling pathway biu04062   Chemokine signaling pathway biu04072   Phospholipase D signaling pathway biu04114   Oocyte meiosis biu04211   Longevity regulating pathway biu04213   Longevity regulating pathway - multiple species biu04261   Adrenergic signaling in cardiomyocytes biu04270   Vascular smooth muscle contraction biu04371   Apelin signaling pathway biu04540   Gap junction biu04611   Platelet activation biu04713   Circadian entrainment biu04714   Thermogenesis biu04723   Retrograde endocannabinoid signaling biu04724   Glutamatergic synapse biu04725   Cholinergic synapse biu04727   GABAergic synapse biu04750   Inflammatory mediator regulation of TRP channels biu04911   Insulin secretion biu04912   GnRH signaling pathway biu04913   Ovarian steroidogenesis biu04914   Progesterone-mediated oocyte maturation biu04915   Estrogen signaling pathway biu04916   Melanogenesis biu04918   Thyroid hormone synthesis biu04921   Oxytocin signaling pathway biu04922   Glucagon signaling pathway biu04923   Regulation of lipolysis in adipocytes biu04925   Aldosterone synthesis and secretion biu04926   Relaxin signaling pathway biu04927   Cortisol synthesis and secretion biu04928   Parathyroid hormone synthesis, secretion and action biu04934   Cushing syndrome biu04935   Growth hormone synthesis, secretion and action biu04970   Salivary secretion biu04971   Gastric acid secretion biu04972   Pancreatic secretion biu04976   Bile secretion biu05032   Morphine addiction biu05163   Human cytomegalovirus infection biu05166   Human T-cell leukemia virus 1 infection biu05200   Pathways in cancer biu05207   Chemical carcinogenesis - receptor activation biu05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:biu00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     109574822 (ADCY2)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     109574822 (ADCY2)    04371 Apelin signaling pathway     109574822 (ADCY2)    04020 Calcium signaling pathway     109574822 (ADCY2)    04072 Phospholipase D signaling pathway     109574822 (ADCY2)    04024 cAMP signaling pathway     109574822 (ADCY2)    04022 cGMP-PKG signaling pathway     109574822 (ADCY2)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     109574822 (ADCY2)   09144 Cellular community - eukaryotes    04540 Gap junction     109574822 (ADCY2)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     109574822 (ADCY2)    04062 Chemokine signaling pathway     109574822 (ADCY2)   09152 Endocrine system    04911 Insulin secretion     109574822 (ADCY2)    04922 Glucagon signaling pathway     109574822 (ADCY2)    04923 Regulation of lipolysis in adipocytes     109574822 (ADCY2)    04912 GnRH signaling pathway     109574822 (ADCY2)    04913 Ovarian steroidogenesis     109574822 (ADCY2)    04915 Estrogen signaling pathway     109574822 (ADCY2)    04914 Progesterone-mediated oocyte maturation     109574822 (ADCY2)    04921 Oxytocin signaling pathway     109574822 (ADCY2)    04926 Relaxin signaling pathway     109574822 (ADCY2)    04935 Growth hormone synthesis, secretion and action     109574822 (ADCY2)    04918 Thyroid hormone synthesis     109574822 (ADCY2)    04928 Parathyroid hormone synthesis, secretion and action     109574822 (ADCY2)    04916 Melanogenesis     109574822 (ADCY2)    04925 Aldosterone synthesis and secretion     109574822 (ADCY2)    04927 Cortisol synthesis and secretion     109574822 (ADCY2)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     109574822 (ADCY2)    04270 Vascular smooth muscle contraction     109574822 (ADCY2)   09154 Digestive system    04970 Salivary secretion     109574822 (ADCY2)    04971 Gastric acid secretion     109574822 (ADCY2)    04972 Pancreatic secretion     109574822 (ADCY2)    04976 Bile secretion     109574822 (ADCY2)   09156 Nervous system    04724 Glutamatergic synapse     109574822 (ADCY2)    04727 GABAergic synapse     109574822 (ADCY2)    04725 Cholinergic synapse     109574822 (ADCY2)    04723 Retrograde endocannabinoid signaling     109574822 (ADCY2)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     109574822 (ADCY2)   09149 Aging    04211 Longevity regulating pathway     109574822 (ADCY2)    04213 Longevity regulating pathway - multiple species     109574822 (ADCY2)   09159 Environmental adaptation    04713 Circadian entrainment     109574822 (ADCY2)    04714 Thermogenesis     109574822 (ADCY2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     109574822 (ADCY2)    05207 Chemical carcinogenesis - receptor activation     109574822 (ADCY2)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     109574822 (ADCY2)    05163 Human cytomegalovirus infection     109574822 (ADCY2)   09165 Substance dependence    05032 Morphine addiction     109574822 (ADCY2)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     109574822 (ADCY2)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     109574822 (ADCY2)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     109574822 (ADCY2) Enzymes [BR:biu01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      109574822 (ADCY2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N HNOBA Motif Other DBs NCBI-GeneID:  109574822 NCBI-ProteinID:  XP_019838349 UniProt:  A0A6P5DKR0 LinkDB All DBs Position 20:complement(69275132..69710617) Genome browser AA seq 972 aa AA seqDB search MGYLFMCFGGTVSPWDQVSFFLFIIFVVYTMLPFNMRDAIIASVLTSSSHTIVLSVCLSA TPGAKEHLVWQILANVIIFICGNLAGAYHKHLMELALQQTYQDTCNCIKSRIKLEFEKRQ QERLLLSLLPAHIAMEMKAEIIQRLQGPKAGQMENTNNFHNLYVKRHTNVSILYADIVGF TRLASDCSPGELVHMLNELFGKFDQIAKENECMRIKILGDCYYCVSGLPISLPNHAKNCV KMGLDMCEAIKKVRDATGVDINMRVGVHSGNVLCGVIGLQKWQYDVWSHDVTLANHMEAG GVPGRVHISSVTLQHLNGAYKVEEGDGDIRDPYLKQHLVKTYFVINPKGERRSPQHLFRP RHTLDGAKMRASVRMTRYLESWGAAKPFAHLHHRDSMTTENGKISTTDVPMGQHNFQNRT LRTKSQKKRFEEELNERMIQAIDGINAQKQWLKSEDIQRISLLFYNKIIEKEYRATALPA FKYYVTCACLIFFCIFIVQVLVLPKTSILGISFGAAFLSLAFILFVCFAGQLLQCSKKAS ASLLWLLKSSGIIANRPWPRISLTVITTAIILTMAVFNMFFLSDSEETILPTANASNTSL SGASNQAAILRAQNLFFLPYFIYSCILGLISCSVFLRVNYELKMLIMMAALVGYNTIFLH THAPLLDDYSQVLFERPGIWKDLKTMGSVSLFIFFITLLVLGRQNEYYCRLDFLWKNKFK KEREEIETMENLNRVLLENVLPAHVAEHFLARSLKNEELYHQSYDCVCVMFASIPDFKEF YTESDVNKEGLECLRLLNEIIADFDDLLSKPKFSGVEKIKTIGSTYMAATGLSAVPSQEH AQEPERQYMHIGTMVEFAFALVGKLDAINKHSFNDFKLRVGINHGPVIAGVIGAQKPQYD IWGNTVNVASRMDSTGVLDKIQVTEETSIILQTLGYTCTCRGIINVKGKGDLKTYFVNTE MSRSLSQSNLTS NT seq 2919 nt NT seq  +upstreamnt  +downstreamnt atgggctacttgttcatgtgtttcgggggcaccgtctctccctgggaccaggtgtcattc ttcctcttcatcatcttcgtggtgtacaccatgctgcccttcaacatgcgagatgccatc atcgccagtgtcctcacctcctcttctcacaccatcgtgctgagcgtctgcctgtctgca acaccaggggccaaggagcacctggtctggcagatcctggccaacgtgatcatcttcatc tgcgggaacctggcgggggcataccataagcacctcatggagctcgctctgcagcagacg tatcaggacacgtgcaactgcatcaagtcccggatcaagctggaatttgaaaaacgtcag caggagcggctgctgctgtccctgctgccggcacacatagccatggagatgaaagcggag atcatccagaggctgcagggcccmaaagccggccagatggagaacaccaacaacttccac aacctctacgtcaagcggcacaccaacgtcagtatcctctatgcggacattgttgggttc acccgtctggccagtgactgctcccctggagagctcgtccatatgctgaatgaactcttt ggaaagttcgatcaaattgcaaaggagaatgaatgcatgagaataaaaattttaggagac tgctactactgtgtgtccggactgcctatatctctccctaaccatgccaagaattgtgtg aaaatgggactggatatgtgtgaagccataaagaaagtgagggacgccaccggagtggac atcaacatgcgcgtgggagtgcattctgggaacgtgctgtgcggcgtgatcgggctgcag aagtggcagtacgacgtgtggtcacatgacgtcaccctggccaaccacatggaagctgga ggggtccctggacgtgttcacatttcttctgttaccctgcaacacttgaatggagcttac aaagtggaagaaggcgatggtgacatcagagacccgtatttaaagcaacatttggtgaaa acttactttgtaatcaaccccaagggagagcggcggagccctcagcacctctttaggcct cgacacacccttgacggagcgaagatgagggcttctgtccgcatgacccggtacctggag tcctggggggcggccaagccctttgcacacctgcatcacagagacagcatgactacggag aacggcaagatcagcaccacggatgtaccaatgggtcagcataattttcaaaatcgcacc ttaagaaccaagtcacaaaagaaaagatttgaagaggaattaaatgaaaggatgattcaa gcaattgatggaatcaatgcacaaaagcaatggctcaagtcygaagacattcagagaatc tcattgcttttctacaataaaataatagaaaaagaataccgagccaccgcactgccggcc ttcaagtattacgtgacttgcgcttgcctgatcttcttctgcatctttatcgtgcaggtt ctggtcttacccaaaacgtccattctcggratttcctttggagcggcgtttctctcactt gcctttatccttttcgtctgctttgctggacagcttttgcaatgcagcaagaaagcatct gcttctctcctgtggcttttaaagtcatcgggcatcatcgccaaccggccctggcctcgg atctccctgacggtcatcaccacrgccatcatattgaccatggccgtgttcaatatgttt ttcctgagtgactcagaggaaacaattcttccgactgccaacgcgtccaacacaagtctt tctggcgcaagtaaccaggcagcaattctgcgtgcgcaaaatttgtttttcctgccgtac tttatatacagctgcatccttgggctgatctcctgttccgtcttcctgcgtgtgaattac gagctgaagatgctgatcatgatggcagccttggtgggctacaacaccatcttcctccac actcacgctcccctcctggacgactacagccaggtcctgttcgagagaccaggcatttgg aaagacctaaagaccatgggctcagtatctctctttatatttttcatcacactgcttgtt ctgggcagacagaatgaatattactgtaggttagacttcttatggaagaacaagttcaaa aaagagcgggaggagatagaaaccatggagaacttgaaccgagtgctgctggagaacgtg cttcctgcgcacgtggctgagcacttcctggcgcggagcctgaagaacgaggagttatac caccagtcctacgactgcgtctgcgtcatgtttgcctccattcctgatttcaaagaattc tatacagaatcagacgtgaacaaggagggtttggaatgccttcggctcctgaacgagatc attgccgactttgatgatctgctctccaagccgaagttcagtggtgttgaaaagatcaag accatcggcagcacgtacatggcagcgacaggtctgagcgcggtgcccagccaggagcac gcccaggagccggagaggcagtacatgcacattggcaccatggtggagtttgcatttgcc ctggtggggaagctggatgccatcaacaagcactccttcaatgacttcaagttacgagta ggtattaaccatggccctgtcatagccggtgtgattggagctcagaagccgcagtatgac atctggggcaacaccgtcaatgtggccagcaggatggacagcaccggagtcctggacaaa atccaggtgacagaggagacgagcatcatcctacagaccctaggctacacgtgcacgtgt cggggaatcatcaacgtgaaaggaaagggggacctgaagacctacttcgtcaacacggag atgtcacggtccctttctcagagcaacctgacctcctga

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