Bacillus megaterium WSH-002: BMWSH_0575
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Entry
BMWSH_0575 CDS
T01890
Symbol
folC
Name
(GenBank) Folylpolyglutamate synthase / Dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
bmh
Bacillus megaterium WSH-002
Pathway
bmh00790
Folate biosynthesis
bmh01100
Metabolic pathways
bmh01240
Biosynthesis of cofactors
Module
bmh_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
bmh00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
BMWSH_0575 (folC)
Enzymes [BR:
bmh01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
BMWSH_0575 (folC)
6.3.2.17 tetrahydrofolate synthase
BMWSH_0575 (folC)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Myotub-related
Motif
Other DBs
NCBI-ProteinID:
AEN87459
UniProt:
A0A8D4BM25
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Position
597486..598784
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AA seq
432 aa
AA seq
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MITTYEEALDWIHNRLRFGIKPGLERMEWMLEQLDFPQQNINAIHVAGTNGKGSTVSYLR
NMLEEAGYKVGTFTSPYIETFNERISVNGQPISNEAMTALVQEVKPVVERLEHTDLGSAT
EFEVITIMAFLYFGYHDSVDYVVFETGLGGRYDSTNVVNPMVSIVTNIGFDHMAILGDTV
EEIAAEKAGIIKKEVPIITGAEQVKALDVITEEANSKQASLFVLGKEFKIENYEPLANGE
GFTLKTPYGTFEHLQLNMLGYHQVKNAALAVMAVCYLKEKKKLSISNEQMIKGIQHTKWN
GRFEIVNEHPLTIIDGAHNAEGIDSLLSTLRLHYEDRNIHLVFSCLNDKSADRMVQELET
IAASITFTSFDFPRARPAQELYEMSTHHNKHMDEEWKKAIAYVEEKATGEQDMVVITGSL
YFISEVRAFLLK
NT seq
1299 nt
NT seq
+upstream
nt +downstream
nt
atgataacgacatatgaagaagcgcttgattggattcataacagacttcgatttggaatc
aagccgggattagaacgaatggaatggatgctagagcagcttgattttccgcagcaaaat
ataaatgctattcatgttgctgggacgaatggtaaaggttctaccgtttcttatttgcga
aacatgttagaagaagcagggtataaagttggaacgtttacttccccttatatcgaaaca
tttaatgagcggatcagtgtgaatggacagcctatttcaaatgaagcaatgaccgctctt
gttcaggaagtaaagcctgtagtggagcgactagaacatacggatttagggtcagcaacg
gaatttgaagtgattacaatcatggcttttctttatttcggctatcatgattcagttgac
tatgttgtgtttgaaacaggtcttgggggacgatatgattcaacaaacgttgtgaatcct
atggtgagtattgttacaaacattggatttgatcacatggcgatactaggtgatacggta
gaagaaattgcagcagaaaaagcggggattattaaaaaagaagttcctattattactggt
gcagagcaagtaaaggcgcttgacgtcattacagaagaggcaaattcgaagcaggcttcg
ttatttgtgttaggaaaagaatttaaaattgaaaactatgagcctttagcaaatggagaa
ggctttacgttaaaaacgccgtatggtacatttgaacacttgcaattaaatatgcttggc
tatcatcaagttaaaaatgcagctttggctgtgatggccgtttgttatttaaaagaaaag
aaaaagctttctatctccaatgagcaaatgataaaagggattcagcatacaaagtggaat
ggccgctttgagatagtaaatgagcatcctttaacgattattgatggggctcataatgca
gaaggcattgatagcttgttatctactttacgccttcattatgaagatcgaaacattcat
ttagttttcagctgcttaaatgataaaagcgcagatcgaatggtccaagaacttgaaaca
atcgctgcaagtattacatttacgtcgtttgactttcctcgtgctcgtccggctcaagag
ctttatgagatgagtactcatcataataagcatatggacgaggagtggaaaaaagcaatt
gcttacgtagaggaaaaggcgacaggtgaacaagacatggtcgtaattacagggtctctg
tattttatatcagaagtaagggcttttcttctaaaatga
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