Bos mutus (wild yak): 102264992 Help Entry 102264992         CDS       T02919                                  Gene name CDK6 Definition (RefSeq) cyclin dependent kinase 6   KO K02091   cyclin-dependent kinase 6 [EC:2.7.11.22] Organism bom  Bos mutus (wild yak) Pathway bom04110   Cell cycle bom04115   p53 signaling pathway bom04151   PI3K-Akt signaling pathway bom04218   Cellular senescence bom04934   Cushing syndrome bom05160   Hepatitis C bom05162   Measles bom05163   Human cytomegalovirus infection bom05164   Influenza A bom05165   Human papillomavirus infection bom05167   Kaposi sarcoma-associated herpesvirus infection bom05169   Epstein-Barr virus infection bom05200   Pathways in cancer bom05203   Viral carcinogenesis bom05206   MicroRNAs in cancer bom05212   Pancreatic cancer bom05214   Glioma bom05218   Melanoma bom05220   Chronic myeloid leukemia bom05222   Small cell lung cancer bom05223   Non-small cell lung cancer bom05224   Breast cancer bom05225   Hepatocellular carcinoma Brite KEGG Orthology (KO) [BR:bom00001]  09130 Environmental Information Processing   09132 Signal transduction    04151 PI3K-Akt signaling pathway     102264992 (CDK6)  09140 Cellular Processes   09143 Cell growth and death    04110 Cell cycle     102264992 (CDK6)    04115 p53 signaling pathway     102264992 (CDK6)    04218 Cellular senescence     102264992 (CDK6)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102264992 (CDK6)    05206 MicroRNAs in cancer     102264992 (CDK6)    05203 Viral carcinogenesis     102264992 (CDK6)   09162 Cancer: specific types    05212 Pancreatic cancer     102264992 (CDK6)    05225 Hepatocellular carcinoma     102264992 (CDK6)    05214 Glioma     102264992 (CDK6)    05220 Chronic myeloid leukemia     102264992 (CDK6)    05218 Melanoma     102264992 (CDK6)    05224 Breast cancer     102264992 (CDK6)    05222 Small cell lung cancer     102264992 (CDK6)    05223 Non-small cell lung cancer     102264992 (CDK6)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     102264992 (CDK6)   09172 Infectious disease: viral    05160 Hepatitis C     102264992 (CDK6)    05164 Influenza A     102264992 (CDK6)    05162 Measles     102264992 (CDK6)    05163 Human cytomegalovirus infection     102264992 (CDK6)    05167 Kaposi sarcoma-associated herpesvirus infection     102264992 (CDK6)    05169 Epstein-Barr virus infection     102264992 (CDK6)    05165 Human papillomavirus infection     102264992 (CDK6)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:bom01001]     102264992 (CDK6) Enzymes [BR:bom01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.22  cyclin-dependent kinase      102264992 (CDK6) Protein kinases [BR:bom01001]  Serine/threonine kinases: CMGC group   CDK family    102264992 (CDK6) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr APH Kdo Kinase-like RIO1 FTA2 Motif Other DBs NCBI-GeneID:  102264992 NCBI-ProteinID:  XP_005906335 UniProt:  L8I065 LinkDB All DBs Position Un AA seq 326 aa AA seqDB search MEKDGLSRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIR EVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTE TIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVV VTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGE EDWPRDVALPRQAFHSKSPQPIEKFVTDIDEQGKDLLLKCLTFNPAKRISAYSALSHPYF HDLERRKENLDSHLPPSQNSSEMNTA NT seq 981 nt NT seq  +upstreamnt  +downstreamnt atggagaaggacggcctgagccgtgccgaccagcagtatgagtgcgtggcggagatcggg gagggcgcctacgggaaggtgttcaaggcccgggacctgaagaacggaggccgtttcgtg gcgctgaagcgcgtgcgagtgcagactggcgaggagggcatgccgctctccaccatccgc gaggtggcggtgctgaggcacctggagaccttcgagcaccccaacgtggtcaggttgttt gacgtgtgtacagtgtcacgaacagacagagaaaccaaactaacgttagtgtttgaacac gttgatcaagacttgaccacttatttggataaagtgccagaacctggagtgcctactgaa accataaaggatatgatgtttcagcttctccgaggcctggactttcttcattctcaccga gtggtgcatcgtgatctaaaaccacagaacattctggtgaccagcagtggacaaataaag ctggctgacttcggccttgctcgcatctacagttttcagatggctcttacctcagtggtc gtcacgctgtggtaccgagctccggaagtcctgcttcagtccagctacgccacccctgtg gatctctggagcgttggctgcatctttgcagagatgtttcgtagaaagccgctttttcgt ggaagttcagatgtcgaccaactaggaaaaatcttggacgtaattggactcccgggagaa gaggactggcctagagatgttgccctacccaggcaggcttttcactcaaaatcccctcaa ccaattgagaagtttgtaacagacattgatgaacaaggcaaagacctgcttctgaagtgc ttgacatttaatccagccaaaagaatatcagcatacagtgccctgtctcacccatacttc cacgatctggagaggcgcaaggaaaacctggattcccacctgccgcccagccagaacagc tcggaaatgaataccgcttaa

Bos mutus (wild yak): 102278545 Help Entry 102278545         CDS       T02919                                  Gene name CDK4 Definition (RefSeq) cyclin dependent kinase 4   KO K02089   cyclin-dependent kinase 4 [EC:2.7.11.22] Organism bom  Bos mutus (wild yak) Pathway bom01522   Endocrine resistance bom04110   Cell cycle bom04115   p53 signaling pathway bom04151   PI3K-Akt signaling pathway bom04218   Cellular senescence bom04530   Tight junction bom04660   T cell receptor signaling pathway bom04933   AGE-RAGE signaling pathway in diabetic complications bom04934   Cushing syndrome bom05160   Hepatitis C bom05162   Measles bom05163   Human cytomegalovirus infection bom05164   Influenza A bom05165   Human papillomavirus infection bom05166   Human T-cell leukemia virus 1 infection bom05167   Kaposi sarcoma-associated herpesvirus infection bom05169   Epstein-Barr virus infection bom05200   Pathways in cancer bom05203   Viral carcinogenesis bom05212   Pancreatic cancer bom05214   Glioma bom05218   Melanoma bom05219   Bladder cancer bom05220   Chronic myeloid leukemia bom05222   Small cell lung cancer bom05223   Non-small cell lung cancer bom05224   Breast cancer bom05225   Hepatocellular carcinoma Brite KEGG Orthology (KO) [BR:bom00001]  09130 Environmental Information Processing   09132 Signal transduction    04151 PI3K-Akt signaling pathway     102278545 (CDK4)  09140 Cellular Processes   09143 Cell growth and death    04110 Cell cycle     102278545 (CDK4)    04115 p53 signaling pathway     102278545 (CDK4)    04218 Cellular senescence     102278545 (CDK4)   09144 Cellular community - eukaryotes    04530 Tight junction     102278545 (CDK4)  09150 Organismal Systems   09151 Immune system    04660 T cell receptor signaling pathway     102278545 (CDK4)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102278545 (CDK4)    05203 Viral carcinogenesis     102278545 (CDK4)   09162 Cancer: specific types    05212 Pancreatic cancer     102278545 (CDK4)    05225 Hepatocellular carcinoma     102278545 (CDK4)    05214 Glioma     102278545 (CDK4)    05220 Chronic myeloid leukemia     102278545 (CDK4)    05218 Melanoma     102278545 (CDK4)    05219 Bladder cancer     102278545 (CDK4)    05224 Breast cancer     102278545 (CDK4)    05222 Small cell lung cancer     102278545 (CDK4)    05223 Non-small cell lung cancer     102278545 (CDK4)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     102278545 (CDK4)    04934 Cushing syndrome     102278545 (CDK4)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102278545 (CDK4)    05160 Hepatitis C     102278545 (CDK4)    05164 Influenza A     102278545 (CDK4)    05162 Measles     102278545 (CDK4)    05163 Human cytomegalovirus infection     102278545 (CDK4)    05167 Kaposi sarcoma-associated herpesvirus infection     102278545 (CDK4)    05169 Epstein-Barr virus infection     102278545 (CDK4)    05165 Human papillomavirus infection     102278545 (CDK4)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     102278545 (CDK4)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:bom01001]     102278545 (CDK4) Enzymes [BR:bom01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.22  cyclin-dependent kinase      102278545 (CDK4) Protein kinases [BR:bom01001]  Serine/threonine kinases: CMGC group   CDK family    102278545 (CDK4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr APH Kdo Kinase-like Motif Other DBs NCBI-GeneID:  102278545 NCBI-ProteinID:  XP_005901726 UniProt:  A0A6B0RYR7 LinkDB All DBs Position Un AA seq 303 aa AA seqDB search MATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGAGGGLPISTVREVALL RRLEAFEHPNVVRLMDVCATARTDRETKVTLVFEHVDQDLRTYLDKAPPPGLPVETIKDL MRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWY RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPR DVSLPRGAFSPRGPRPVQSVVPELEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKAEG DAE NT seq 912 nt NT seq  +upstreamnt  +downstreamnt atggctacctcccgatatgagccagtggctgagattggtgtcggtgcctatgggacagtg tacaaggcccgtgatccccacagtggccactttgtggccctcaagagtgtaagagtcccc aatggaggaggtgctggagggggcctgcccatcagcaccgttcgggaggtggccttactg cggcgtctggaggcttttgagcatcccaatgttgtcaggcttatggacgtctgtgcaaca gcccgaactgaccgggagaccaaagtgaccctggtgtttgagcatgtggaccaagatctc aggacatatctggacaaggcacccccaccaggcttgccagtggagaccataaaagatctc atgcgccaatttctaagaggcctggatttccttcatgccaactgcattgttcaccgagac ctgaagccagagaacattctggtgacaagtggtgggacagtcaagctggctgactttggc ctggccagaatctacagctaccagatggcacttacacctgtggttgttacactctggtat cgtgctccagaagttcttttgcagtctacgtatgcaacacccgtggacatgtggagcgtt ggctgtatctttgcagagatgtttcgtcgaaagcctctcttctgtggaaactctgaagct gaccagttaggcaaaatctttgacctgattggactgcccccagaggatgactggccccga gatgtctctctaccccgaggagccttttccccccgagggccccgcccagtgcagtcggtg gtccctgagctggaggaatctggagcacagctgctgctggagatgctgacttttaaccca cacaagcgaatctctgccttccgagccctgcagcactcttatctacacaaggcagaaggt gacgcagagtga

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