Bos mutus (wild yak): 102265325 Help Entry 102265325         CDS       T02919                                  Gene name ADCY6 Definition (RefSeq) adenylate cyclase 6   KO K08046   adenylate cyclase 6 [EC:4.6.1.1] Organism bom  Bos mutus (wild yak) Pathway bom00230   Purine metabolism bom01100   Metabolic pathways bom01522   Endocrine resistance bom04015   Rap1 signaling pathway bom04022   cGMP-PKG signaling pathway bom04024   cAMP signaling pathway bom04062   Chemokine signaling pathway bom04072   Phospholipase D signaling pathway bom04114   Oocyte meiosis bom04211   Longevity regulating pathway bom04213   Longevity regulating pathway - multiple species bom04261   Adrenergic signaling in cardiomyocytes bom04270   Vascular smooth muscle contraction bom04371   Apelin signaling pathway bom04540   Gap junction bom04611   Platelet activation bom04713   Circadian entrainment bom04714   Thermogenesis bom04723   Retrograde endocannabinoid signaling bom04724   Glutamatergic synapse bom04725   Cholinergic synapse bom04727   GABAergic synapse bom04742   Taste transduction bom04750   Inflammatory mediator regulation of TRP channels bom04911   Insulin secretion bom04912   GnRH signaling pathway bom04913   Ovarian steroidogenesis bom04914   Progesterone-mediated oocyte maturation bom04915   Estrogen signaling pathway bom04916   Melanogenesis bom04918   Thyroid hormone synthesis bom04921   Oxytocin signaling pathway bom04923   Regulation of lipolysis in adipocytes bom04924   Renin secretion bom04925   Aldosterone synthesis and secretion bom04926   Relaxin signaling pathway bom04927   Cortisol synthesis and secretion bom04928   Parathyroid hormone synthesis, secretion and action bom04934   Cushing syndrome bom04935   Growth hormone synthesis, secretion and action bom04961   Endocrine and other factor-regulated calcium reabsorption bom04962   Vasopressin-regulated water reabsorption bom04970   Salivary secretion bom04971   Gastric acid secretion bom04972   Pancreatic secretion bom04976   Bile secretion bom05032   Morphine addiction bom05163   Human cytomegalovirus infection bom05166   Human T-cell leukemia virus 1 infection bom05200   Pathways in cancer bom05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:bom00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     102265325 (ADCY6)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     102265325 (ADCY6)    04371 Apelin signaling pathway     102265325 (ADCY6)    04072 Phospholipase D signaling pathway     102265325 (ADCY6)    04024 cAMP signaling pathway     102265325 (ADCY6)    04022 cGMP-PKG signaling pathway     102265325 (ADCY6)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     102265325 (ADCY6)   09144 Cellular community - eukaryotes    04540 Gap junction     102265325 (ADCY6)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     102265325 (ADCY6)    04062 Chemokine signaling pathway     102265325 (ADCY6)   09152 Endocrine system    04911 Insulin secretion     102265325 (ADCY6)    04923 Regulation of lipolysis in adipocytes     102265325 (ADCY6)    04912 GnRH signaling pathway     102265325 (ADCY6)    04913 Ovarian steroidogenesis     102265325 (ADCY6)    04915 Estrogen signaling pathway     102265325 (ADCY6)    04914 Progesterone-mediated oocyte maturation     102265325 (ADCY6)    04921 Oxytocin signaling pathway     102265325 (ADCY6)    04926 Relaxin signaling pathway     102265325 (ADCY6)    04935 Growth hormone synthesis, secretion and action     102265325 (ADCY6)    04918 Thyroid hormone synthesis     102265325 (ADCY6)    04928 Parathyroid hormone synthesis, secretion and action     102265325 (ADCY6)    04916 Melanogenesis     102265325 (ADCY6)    04924 Renin secretion     102265325 (ADCY6)    04925 Aldosterone synthesis and secretion     102265325 (ADCY6)    04927 Cortisol synthesis and secretion     102265325 (ADCY6)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     102265325 (ADCY6)    04270 Vascular smooth muscle contraction     102265325 (ADCY6)   09154 Digestive system    04970 Salivary secretion     102265325 (ADCY6)    04971 Gastric acid secretion     102265325 (ADCY6)    04972 Pancreatic secretion     102265325 (ADCY6)    04976 Bile secretion     102265325 (ADCY6)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     102265325 (ADCY6)    04961 Endocrine and other factor-regulated calcium reabsorption     102265325 (ADCY6)   09156 Nervous system    04724 Glutamatergic synapse     102265325 (ADCY6)    04727 GABAergic synapse     102265325 (ADCY6)    04725 Cholinergic synapse     102265325 (ADCY6)    04723 Retrograde endocannabinoid signaling     102265325 (ADCY6)   09157 Sensory system    04742 Taste transduction     102265325 (ADCY6)    04750 Inflammatory mediator regulation of TRP channels     102265325 (ADCY6)   09149 Aging    04211 Longevity regulating pathway     102265325 (ADCY6)    04213 Longevity regulating pathway - multiple species     102265325 (ADCY6)   09159 Environmental adaptation    04713 Circadian entrainment     102265325 (ADCY6)    04714 Thermogenesis     102265325 (ADCY6)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102265325 (ADCY6)   09165 Substance dependence    05032 Morphine addiction     102265325 (ADCY6)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     102265325 (ADCY6)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     102265325 (ADCY6)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102265325 (ADCY6)    05163 Human cytomegalovirus infection     102265325 (ADCY6)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     102265325 (ADCY6) Enzymes [BR:bom01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      102265325 (ADCY6) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  AC_N Guanylate_cyc DUF1053 HNOBA TBK1_ULD Motif Other DBs NCBI-GeneID:  102265325 NCBI-ProteinID:  XP_005896433 LinkDB All DBs Position Un AA seq 1164 aa AA seqDB search MSWFSGLLVPKVDERKTAWGERNGQQRPRRGTRTSGFCTPRYMSCLQGAQPPXPATAPRC PWQDEAFIRRGGPGKGPELGLRAVALGFEDPEVAGAVGAAEVAPAVATRSRRACWRQLVQ VFQSKQFRSAKLERLYQRYFFQMNQSSLTLLMAALVLLTAVLLAFHAAPARPQPAYVALL ACAATLFVALMVVCNRHSFRQDSMWVVSYVVLGILVAVQVGGALAADPRSPSAGLWCPVF FVYITYTLLPIRMRAAVFSGLGLSTLHLVLAWQLNRGDAFLWKQLGANMLLFLCTNVIGI CTHYPAEVSQRQAFQETRGYIQARLHLQHENRQQERLLLSVLPQHVAMEMKEDINTKKED MMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCLRIK ILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRVHCGV LGLRKWQFDVWSNDVTLANHMEAGGRAGRIHITRATLQYLNGDYEVEPGRGGERNAYLKE QHIETFLILGASQKRKEEKAMLAKLQRARANSMEGLMPRWVPDRAFSRTKDSKAFRQMGI DDSSKDNRGAQDALNPEDEVDEFLGRAIDARSIDQLRKDHVRRFLLTFQREDLEKKYSRK VDPRFGAYVACALLVFCFICFIQLVVFPRSALMLGIHASIFLLLLVTVLTCAVYSCGSLF PEALQRVSRSIVRSRAHSTAVGIFSVLLVFTSAVASMFTCNHTPLRTCAARMLNLTPADI TACHLQQLNYSLGLDAPLCEGTAPTCSFPEYFIGNVLLSLLASSVFLHISSIGKLAMIFV LGLVYLVLLLLGPPATIFDNYDLLLGVHGLASSNETFDGLDCPAAGRVALKYMTPVILLV FALALYLHAQQVESTARLDFLWKLQATGEKEEMEELQAYNRRLLHNILPKDVAAHFLARE RRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEIISEERF RQLEKIKTIGSTYMAASGLNASTYDQVGRSHITALADYAMRLMEQMKHINEHSFNNFQMK IGLNMGPVVAGVIGARKPQYDIWGNTVNVSSRMDSTGVPDRIQVTTDLYQVLAAKGYQLE CRGVVKVKGKGEMTTYFLNGGPRS NT seq 3495 nt NT seq  +upstreamnt  +downstreamnt atgtcatggtttagcggcctcttggtccccaaggtggatgaacggaaaacagcctggggg gagcgcaatgggcagcagcggccgcgccgtgggacccgcaccagtggcttctgcacgccc cgctacatgagctgcctccagggtgcgcagccacccnnacccgccactgcccctcggtgc ccctggcaggatgaggccttcatccggagggggggcccaggcaagggcccggagctgggg ctgcgggcggtggccctgggcttcgaggaccctgaggtggccggggccgtcggagcagcg gaggtggcgcctgccgtggccaccaggagcaggcgggcctgctggcgccagctggtgcag gtgttccagtcgaagcagttccgctcggccaagctggagcgcctgtaccagcgctacttc ttccagatgaaccagagcagcctgacgctgctcatggcggcgctcgtgctgctcacggcc gtgctgctggccttccacgcagcgcctgcccgccctcagcccgcctacgtggccctgctg gcctgtgccgccaccctcttcgtggcactcatggtggtgtgcaaccggcacagcttccgc caggactccatgtgggtggtgagctacgtggtgctgggcatcctggtggccgtgcaggtc gggggcgccttggcagccgacccgcgtagcccgtctgcaggcctctggtgccctgtgttc tttgtctacatcacctacacactccttcccatccgcatgcgggctgcagtcttcagcggc ctgggcctctccaccctgcacttggtcttggcctggcagctcaaccgtggtgacgccttc ctctggaagcagcttggagccaacatgctgctgttcctctgcaccaatgtcattggcatc tgcacacactatccggctgaggtgtctcagcgccaggcatttcaagagacccgcggttac atccaggcccggctgcacctgcagcatgagaaccggcagcaggagcggctgctgctgtct gtgttgccccagcatgttgccatggagatgaaagaagacatcaacacaaagaaagaagac atgatgtttcataagatctacatccagaagcacgacaatgtcagcatcctgtttgcggac attgaaggcttcaccagcctggcatcccagtgcacagcgcaggagctggtcatgaccctg aacgagctctttgcccggttcgacaagctggctgcggaaaatcactgcctgaggatcaag atcttaggggactgttactactgcgtgtcagggctgccagaggcccgggcagaccatgcc cactgctgcgtggagatgggggtggacatgatcgaggctatctcgctggtgcgcgaggtg acaggtgtaaacgtgaacatgcgcgtgggcatccacagcgggcgtgtgcactgtggcgtc cttggcttgcggaaatggcagtttgatgtgtggtccaatgacgtgactctggccaaccac atggaggccgggggccgggccggccgcatccacatcacccgggccacgctgcagtacctg aatggggactacgaagtggagccgggccgcggtggggagcgcaacgcctacctcaaggag cagcacattgagaccttcctcatcctgggagccagccagaaacggaaagaagagaaggcc atgctggccaagctgcagcgggcacgggccaactccatggaagggctgatgccacgctgg gtgcctgaccgtgccttctcccggaccaaggactccaaggctttccgccagatgggcatc gatgattccagcaaagacaaccggggtgctcaggatgccctgaaccctgaggatgaggta gacgagttcctgggccgggccattgatgcccgcagcattgatcagctgcgcaaggaccat gtgcgccggttcctgctcaccttccagagagaggatcttgaaaagaagtactcacgcaag gtggacccccgctttggagcctacgtggcctgtgccctgctggtcttctgcttcatctgc ttcatccagcttgttgtcttcccacgctcagctctgatgcttgggatccacgccagtatc ttcctgctgttactggtcaccgtgctgacttgtgccgtgtactcctgtggctctctgttc cctgaggccctgcaacgtgtatctcgcagtatcgtccgctcgagggcacatagcaccgca gttggcatcttttctgtcctgcttgtgttcacctccgccgttgccagcatgttcacctgt aaccacacccccttacgaacttgcgcggcccggatgctgaatttaacccctgctgacatt accgcctgccacctgcagcagctcaattactctctgggcctggatgctcccctgtgtgag ggcaccgcacccacctgcagcttccctgagtacttcattgggaacgtgttgctgagtctc ttggccagctctgtcttcctgcacatcagtagtatcgggaagttggccatgatctttgtc ctggggctcgtttatctggtgctgcttctgctgggtcccccagccaccatctttgacaac tatgacctcctgctgggcgtccatggcttggcttcttccaatgagacctttgatgggctg gactgcccagcggccgggagggtggcactcaaatacatgacccccgtgattctgctggtg tttgcactggcgctgtacctgcatgcccagcaggtggagtccaccgcccgcctggacttc ctctggaagctgcaggcaacaggggagaaggaagagatggaggagctccaggcctacaac cggcggctgctacataacattctgcccaaggacgtggccgcccacttcctggcccgggag cgccggaacgacgagctgtactatcagtcctgtgaatgtgtggccgtcatgtttgcctcc attgccaacttctctgagttctacgtggagctggaggccaacaacgagggtgttgagtgc ctgcgactgctcaatgagatcattgctgatttcgatgagatcatcagtgaggagcgcttc cggcagctggagaagatcaagacaattggtagcacctacatggctgcctctgggctgaac gccagcacctatgatcaggtgggccgctcccacatcactgccctcgccgactatgccatg cggctcatggagcagatgaagcacatcaatgagcactccttcaacaatttccagatgaag atcggactgaacatgggcccagttgtggcaggcgtcattggggctcggaagccacagtat gacatctgggggaacacagtgaatgtctcgagtcgaatggacagcaccggggtccccgac cgaatccaggtgaccacggacctgtaccaggttctagcggccaagggctaccagctggaa tgtcgaggggtggtcaaggtgaagggcaagggggagatgaccacctacttcctcaatggg ggccccaggagttag

Bos mutus (wild yak): 102266966 Help Entry 102266966         CDS       T02919                                  Gene name ADCY7 Definition (RefSeq) adenylate cyclase 7   KO K08047   adenylate cyclase 7 [EC:4.6.1.1] Organism bom  Bos mutus (wild yak) Pathway bom00230   Purine metabolism bom01100   Metabolic pathways bom01522   Endocrine resistance bom04015   Rap1 signaling pathway bom04020   Calcium signaling pathway bom04022   cGMP-PKG signaling pathway bom04024   cAMP signaling pathway bom04062   Chemokine signaling pathway bom04072   Phospholipase D signaling pathway bom04114   Oocyte meiosis bom04211   Longevity regulating pathway bom04213   Longevity regulating pathway - multiple species bom04261   Adrenergic signaling in cardiomyocytes bom04270   Vascular smooth muscle contraction bom04371   Apelin signaling pathway bom04540   Gap junction bom04611   Platelet activation bom04713   Circadian entrainment bom04714   Thermogenesis bom04723   Retrograde endocannabinoid signaling bom04724   Glutamatergic synapse bom04725   Cholinergic synapse bom04727   GABAergic synapse bom04750   Inflammatory mediator regulation of TRP channels bom04911   Insulin secretion bom04912   GnRH signaling pathway bom04913   Ovarian steroidogenesis bom04914   Progesterone-mediated oocyte maturation bom04915   Estrogen signaling pathway bom04916   Melanogenesis bom04918   Thyroid hormone synthesis bom04921   Oxytocin signaling pathway bom04923   Regulation of lipolysis in adipocytes bom04925   Aldosterone synthesis and secretion bom04926   Relaxin signaling pathway bom04927   Cortisol synthesis and secretion bom04928   Parathyroid hormone synthesis, secretion and action bom04934   Cushing syndrome bom04935   Growth hormone synthesis, secretion and action bom04970   Salivary secretion bom04971   Gastric acid secretion bom04972   Pancreatic secretion bom04976   Bile secretion bom05032   Morphine addiction bom05163   Human cytomegalovirus infection bom05166   Human T-cell leukemia virus 1 infection bom05200   Pathways in cancer bom05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:bom00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     102266966 (ADCY7)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     102266966 (ADCY7)    04371 Apelin signaling pathway     102266966 (ADCY7)    04020 Calcium signaling pathway     102266966 (ADCY7)    04072 Phospholipase D signaling pathway     102266966 (ADCY7)    04024 cAMP signaling pathway     102266966 (ADCY7)    04022 cGMP-PKG signaling pathway     102266966 (ADCY7)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     102266966 (ADCY7)   09144 Cellular community - eukaryotes    04540 Gap junction     102266966 (ADCY7)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     102266966 (ADCY7)    04062 Chemokine signaling pathway     102266966 (ADCY7)   09152 Endocrine system    04911 Insulin secretion     102266966 (ADCY7)    04923 Regulation of lipolysis in adipocytes     102266966 (ADCY7)    04912 GnRH signaling pathway     102266966 (ADCY7)    04913 Ovarian steroidogenesis     102266966 (ADCY7)    04915 Estrogen signaling pathway     102266966 (ADCY7)    04914 Progesterone-mediated oocyte maturation     102266966 (ADCY7)    04921 Oxytocin signaling pathway     102266966 (ADCY7)    04926 Relaxin signaling pathway     102266966 (ADCY7)    04935 Growth hormone synthesis, secretion and action     102266966 (ADCY7)    04918 Thyroid hormone synthesis     102266966 (ADCY7)    04928 Parathyroid hormone synthesis, secretion and action     102266966 (ADCY7)    04916 Melanogenesis     102266966 (ADCY7)    04925 Aldosterone synthesis and secretion     102266966 (ADCY7)    04927 Cortisol synthesis and secretion     102266966 (ADCY7)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     102266966 (ADCY7)    04270 Vascular smooth muscle contraction     102266966 (ADCY7)   09154 Digestive system    04970 Salivary secretion     102266966 (ADCY7)    04971 Gastric acid secretion     102266966 (ADCY7)    04972 Pancreatic secretion     102266966 (ADCY7)    04976 Bile secretion     102266966 (ADCY7)   09156 Nervous system    04724 Glutamatergic synapse     102266966 (ADCY7)    04727 GABAergic synapse     102266966 (ADCY7)    04725 Cholinergic synapse     102266966 (ADCY7)    04723 Retrograde endocannabinoid signaling     102266966 (ADCY7)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     102266966 (ADCY7)   09149 Aging    04211 Longevity regulating pathway     102266966 (ADCY7)    04213 Longevity regulating pathway - multiple species     102266966 (ADCY7)   09159 Environmental adaptation    04713 Circadian entrainment     102266966 (ADCY7)    04714 Thermogenesis     102266966 (ADCY7)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102266966 (ADCY7)   09165 Substance dependence    05032 Morphine addiction     102266966 (ADCY7)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     102266966 (ADCY7)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     102266966 (ADCY7)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102266966 (ADCY7)    05163 Human cytomegalovirus infection     102266966 (ADCY7)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     102266966 (ADCY7) Enzymes [BR:bom01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      102266966 (ADCY7) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc DUF1053 AC_N Motif Other DBs NCBI-GeneID:  102266966 NCBI-ProteinID:  XP_005902702 LinkDB All DBs Position Un AA seq 1081 aa AA seqDB search MPAKGRYFLNEGEEGPDQDALYEKYRLTSQHGPLLLMLLLVAIAACTTLIIITFSYGDPS RHRAILGTAFFTLAVFVLLYALVYVECLDRRGLRISALLIWACLVTLGYVLVFDFDSPRK DTCVLGQVPFFLFVVFVVYTLLPFSTWGAVTAGLVSSISHLLVLAMHQEDFTSPPAVAHL QLLATAVVFVCGNLTGAFHKHHMQDASHDLFTYTVKCIQIRRKLRIEKRQQENLLLSVLP AHISMGMKLAIIERLKERGDRRYLPDNNFHNLYVKRHQNVSILYADIVGFTRLASDCSPK ELVVVLNELFGKFDQIAKANECMRIKILGDCYYCVSGLPVSLPNHARNCVKMGLDMCEAI KQVREATGVDISMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGVPGRVHITE ATLKHLDKAYEVEDGHGQQRDPYLKEMNIRTYLVIDPRSQQPPQPSQHNSKNKGDATLKM RASVRMTRYLESWGAARPFAHLNQRESVSSSETLVSHGRRPKAVPLRRHRTPDRSVSPKG RSEDDSYDDEMLSAIEGLSSTRPCCSKSDDFSTFGSIFLEKGFEREYRLAPIPRVRYYFA CASLVFVCILLIHVLLLYSMKTLGVSFGLVACVLGLVLGLCFADVFLRCCPALGKLRAIA ESVETQPLLRVSLAILTIGSLLVIAVVNLPLMPFRDRGLTAGNETGLRAVSGWEMSPCYL LPYYTCSCILAFIACSVFLRMSLELKVVLLTVALVAYLVLFNVYPSWQWDCCGHSLGNLT GTNGTLSSSSSCSWHLKTMTNFYLVLFYTTLIMLSRQIDYYCRLDCLWKKKFKKEHEEFE TMENVNRLLLENVLPAHVAAHFIGDKLNEDWYHQSYDCVCVMFASVPDFKVFYTECDVNK EGLECLRLLNEIIADFDELLLKPKFSGVEKIKTIGSTYMAAAGLSVPSGPENQDLERQHA HIGIMVEFSTALMSKLDGINRHSFNSFRLRVGINHGPVIAGVIGARKPQYDIWGNTVNVA SRMESTGELGKIQVTEETCTILQGLGYSCECRGLIDVKGKGELRTYFVCTDTAKFQGLGL N NT seq 3246 nt NT seq  +upstreamnt  +downstreamnt atgccagccaaggggcgctacttcctcaacgagggcgaggagggccccgaccaggatgcg ctctatgagaagtaccgcctcaccagccagcacgggccactcctgctcatgctcctgttg gtggccatcgctgcctgcaccacgctcatcatcatcaccttcagctacggggacccctcc agacaccgggccatcctggggacggcgttcttcacgctcgccgtgtttgtgctcctctac gctctggtgtacgttgaatgcctcgaccggcgggggctcaggatttccgcgctgctcatc tgggcctgccttgtgacgctgggctacgttttggtgtttgatttcgactcgccgaggaag gacacctgtgtcttggggcaggtgcccttcttcctgttcgtggtcttcgtggtgtacacg ctgctgcccttcagcacgtggggcgccgtcacggccggactcgtctccagcatctcccac ctcctggtgctcgcaatgcaccaggaagacttcaccagccctcctgctgtggcccacctg cagctgctggccactgcggtggtcttcgtgtgcgggaacctcacaggcgccttccacaag caccacatgcaggacgcctcccacgacctcttcacctacacagtgaagtgcatccagatt cggcgtaagctgcgcatcgagaagcgccagcaggagaacctgctgctgtctgtgctgcct gcccacatctccatgggcatgaagctggccatcatcgagcggctcaaggagcgcggggac cgccgttacctgcccgacaacaacttccacaacctctacgtcaagaggcaccagaatgtc agcatcctctacgctgacatcgtgggcttcacgcgactggccagtgactgctcccccaaa gagctggtggtggtgctgaatgagctcttcggcaagtttgaccagatcgccaaggccaat gagtgcatgcggattaagatcctgggcgactgctactactgcgtgtccggcttgcctgtg tccctgcccaaccacgcccgtaactgtgtgaagatggggctggacatgtgtgaggccatc aagcaggtgcgggaggccacaggcgtggacatcagcatgcgcgtgggcatccactcggga aacgtgctgtgcggcgtcatcgggctgcgcaagtggcagtacgacgtgtggtcccacgat gtgtccctggccaacaggatggaggcggccggagtccctggccgggtgcacatcacagag gcgacgctgaagcacctggacaaggcgtacgaggtggaggacgggcacgggcagcagcgg gacccttacctcaaagagatgaacatccgcacctacctggtcatcgacccccggagccag cagccgccccagcccagccagcacaactccaagaacaagggggacgcgaccctgaagatg cgggcgtccgtgcgcatgacgcgctacctggagtcctggggggcggctcgccccttcgcg cacctcaaccaacgcgagagcgtgagcagcagtgagacccttgtgtcccatgggcggagg cccaaggctgttcccctgaggcgccatcggacccctgacagaagcgtatcccccaagggg cggtcagaggacgactcatacgatgatgagatgctgtcagccatcgaggggctcagctct accagaccctgctgctccaagtctgatgacttctctacctttgggtccatcttcctggag aagggcttcgagcgagagtaccgcctggcgcccatcccccgggtccgctactacttcgct tgtgccagcctcgtcttcgtctgcatcctgctcatccacgtcttgctgttgtacagtatg aagactctgggtgtgtcctttgggctggtggcctgtgtgctcgggctggtactaggcttg tgcttcgccgatgtgttcttgaggtgctgcccggccctggggaagctccgagccattgcc gagagcgtggagacgcagcccctgctgcgggtgtccctggccatcctgaccatcggcagc ctgctcgtcattgctgtcgtcaacctgcccctgatgcccttccgggaccgggggctgact gctgggaacgagacaggcctgagggctgtgagcggctgggagatgagcccgtgctacctc ctcccgtactacacctgcagctgcatcctggccttcatcgcttgctctgtcttcctgcgg atgagcctggagctgaaggtcgtgctgctgaccgtggccttggtggcctacctggtcctc ttcaacgtctacccgagctggcagtgggactgctgtggccacagcctgggcaacctcacc gggaccaatggcaccctcagcagctcctcatcctgttcatggcatctgaagacgatgacc aatttctacctggtcttgttctacaccaccctcatcatgctctccagacagattgactat tattgccgcctggactgtctgtggaagaagaagttcaagaaggaacacgaggagtttgaa acaatggagaatgtgaaccgccttcttctagagaatgtcctgcccgcgcacgtggctgcc cacttcatcggtgacaagttaaatgaggactggtaccatcagtcctacgactgcgtgtgt gtcatgtttgcgtcggtgccggactttaaagtcttctacacagagtgcgacgtcaacaag gaagggctggagtgcctgcgcctgctcaacgagatcatcgccgactttgacgagctgctg ctaaagcctaagttcagtggtgtggagaagatcaagaccatcggcagcacctacatggcc gccgcggggctcagcgtcccctcggggcctgagaaccaggacctggagcggcagcacgcc cacatcggcatcatggtggagttcagcaccgccctgatgagcaagctggacggcatcaat cggcactccttcaactcctttcgcctccgagtcggcataaaccatgggcctgtgattgct ggagtgattggggcacgaaaacctcagtacgacatctggggaaacacggtcaatgttgcc agtcgaatggagagcactggagaacttggaaaaatccaggttactgaagagacatgtacc atcctccagggactagggtattcctgtgagtgccgcgggctgattgacgtcaaaggcaaa ggtgaactgaggacttactttgtctgtacggacaccgccaagttccaaggcctggggctg aactga

Bos mutus (wild yak): 102267116 Help Entry 102267116         CDS       T02919                                  Gene name ADCY1 Definition (RefSeq) adenylate cyclase 1   KO K08041   adenylate cyclase 1 [EC:4.6.1.1] Organism bom  Bos mutus (wild yak) Pathway bom00230   Purine metabolism bom01100   Metabolic pathways bom01522   Endocrine resistance bom04015   Rap1 signaling pathway bom04020   Calcium signaling pathway bom04022   cGMP-PKG signaling pathway bom04024   cAMP signaling pathway bom04062   Chemokine signaling pathway bom04072   Phospholipase D signaling pathway bom04114   Oocyte meiosis bom04211   Longevity regulating pathway bom04213   Longevity regulating pathway - multiple species bom04261   Adrenergic signaling in cardiomyocytes bom04270   Vascular smooth muscle contraction bom04371   Apelin signaling pathway bom04540   Gap junction bom04611   Platelet activation bom04713   Circadian entrainment bom04714   Thermogenesis bom04720   Long-term potentiation bom04723   Retrograde endocannabinoid signaling bom04724   Glutamatergic synapse bom04725   Cholinergic synapse bom04727   GABAergic synapse bom04750   Inflammatory mediator regulation of TRP channels bom04911   Insulin secretion bom04912   GnRH signaling pathway bom04913   Ovarian steroidogenesis bom04914   Progesterone-mediated oocyte maturation bom04915   Estrogen signaling pathway bom04916   Melanogenesis bom04918   Thyroid hormone synthesis bom04921   Oxytocin signaling pathway bom04923   Regulation of lipolysis in adipocytes bom04925   Aldosterone synthesis and secretion bom04926   Relaxin signaling pathway bom04927   Cortisol synthesis and secretion bom04928   Parathyroid hormone synthesis, secretion and action bom04934   Cushing syndrome bom04935   Growth hormone synthesis, secretion and action bom04970   Salivary secretion bom04971   Gastric acid secretion bom04972   Pancreatic secretion bom04976   Bile secretion bom05032   Morphine addiction bom05142   Chagas disease bom05146   Amoebiasis bom05163   Human cytomegalovirus infection bom05166   Human T-cell leukemia virus 1 infection bom05200   Pathways in cancer bom05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:bom00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     102267116 (ADCY1)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     102267116 (ADCY1)    04371 Apelin signaling pathway     102267116 (ADCY1)    04020 Calcium signaling pathway     102267116 (ADCY1)    04072 Phospholipase D signaling pathway     102267116 (ADCY1)    04024 cAMP signaling pathway     102267116 (ADCY1)    04022 cGMP-PKG signaling pathway     102267116 (ADCY1)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     102267116 (ADCY1)   09144 Cellular community - eukaryotes    04540 Gap junction     102267116 (ADCY1)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     102267116 (ADCY1)    04062 Chemokine signaling pathway     102267116 (ADCY1)   09152 Endocrine system    04911 Insulin secretion     102267116 (ADCY1)    04923 Regulation of lipolysis in adipocytes     102267116 (ADCY1)    04912 GnRH signaling pathway     102267116 (ADCY1)    04913 Ovarian steroidogenesis     102267116 (ADCY1)    04915 Estrogen signaling pathway     102267116 (ADCY1)    04914 Progesterone-mediated oocyte maturation     102267116 (ADCY1)    04921 Oxytocin signaling pathway     102267116 (ADCY1)    04926 Relaxin signaling pathway     102267116 (ADCY1)    04935 Growth hormone synthesis, secretion and action     102267116 (ADCY1)    04918 Thyroid hormone synthesis     102267116 (ADCY1)    04928 Parathyroid hormone synthesis, secretion and action     102267116 (ADCY1)    04916 Melanogenesis     102267116 (ADCY1)    04925 Aldosterone synthesis and secretion     102267116 (ADCY1)    04927 Cortisol synthesis and secretion     102267116 (ADCY1)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     102267116 (ADCY1)    04270 Vascular smooth muscle contraction     102267116 (ADCY1)   09154 Digestive system    04970 Salivary secretion     102267116 (ADCY1)    04971 Gastric acid secretion     102267116 (ADCY1)    04972 Pancreatic secretion     102267116 (ADCY1)    04976 Bile secretion     102267116 (ADCY1)   09156 Nervous system    04724 Glutamatergic synapse     102267116 (ADCY1)    04727 GABAergic synapse     102267116 (ADCY1)    04725 Cholinergic synapse     102267116 (ADCY1)    04720 Long-term potentiation     102267116 (ADCY1)    04723 Retrograde endocannabinoid signaling     102267116 (ADCY1)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     102267116 (ADCY1)   09149 Aging    04211 Longevity regulating pathway     102267116 (ADCY1)    04213 Longevity regulating pathway - multiple species     102267116 (ADCY1)   09159 Environmental adaptation    04713 Circadian entrainment     102267116 (ADCY1)    04714 Thermogenesis     102267116 (ADCY1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102267116 (ADCY1)   09165 Substance dependence    05032 Morphine addiction     102267116 (ADCY1)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     102267116 (ADCY1)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     102267116 (ADCY1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102267116 (ADCY1)    05163 Human cytomegalovirus infection     102267116 (ADCY1)   09174 Infectious disease: parasitic    05146 Amoebiasis     102267116 (ADCY1)    05142 Chagas disease     102267116 (ADCY1)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     102267116 (ADCY1) Enzymes [BR:bom01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      102267116 (ADCY1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N DUF1053 HNOBA Motif Other DBs NCBI-GeneID:  102267116 NCBI-ProteinID:  XP_005891937 LinkDB All DBs Position Un AA seq 1024 aa AA seqDB search TNVRSLQVPQLQQVGQLALLFSLTFALLCCPFALGGHPGAHFFLAAVPATADQGVWQLLL VTFVSYALLPVRSLLAIGFGLVVAASHLLVTATLVPAKRPRLWRTLGANALLFLGVNVYG VFVRILAERAQRKAFLQARNCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPE RIFHKIYIQRHDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIK ILGDCYYCVSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGV LGLRKWQYDVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGHGHERNSFLKT HNIETFFIVPSHRRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVM TCEDDDKRRALRTASEKLRNRSSFSTNVVQTTPGTRVNRYIGRLLEARQMELEMADLNFF TLKYKQAERERKYHQLQDEYFTSAVVLALILAALFGLVYLLIIPQSVAVLLLLVFCICFL VACVLYLHITRVQCFPGCLTIQIRTVLCIFIVVLIYSVAQGCVVGCLPWSWSSSPNGSLV VLSSGGRDPVLPVPPCESAPHALLCGLVGTLPLAIFLRVSSLPKMILLAVLTTSYILVLE LSGYTKAMGAGAISGRSFEPIVAILLFSCTLALHARQVDVKLRLDYLWAAQAEEERDDME KVKLDNKRILFNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIELDGN NMGVECLRLLNEIIADFDELMDKDFYKDLEKIKTIGSTYMAAVGLAPTAGTKAKKCISSH LSTLADFAIEMFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVAS RMDSTGVQGRIQVTEEVHRLLRRGSYRFVCRGKVSVKGKGEMLTYFLEGRTDGNGSQTXX XXXXXXXXXXGRAGLQTRLAAGHPPVPPAAGLPVGAGPGALQGSGLAPGPPGQHLPPGAS GKEA NT seq 3075 nt NT seq  +upstreamnt  +downstreamnt accaacgtccgctcgctgcaggtgccccagctgcagcaggtcggccagctcgcgctgctc ttcagcctcaccttcgctctgctgtgctgtccctttgctctcggcggccaccccggggcc cacttttttttggcagcggtgccggcgacagccgatcagggagtctggcagctccttttg gtcaccttcgtgtcctatgccctgctgcccgtgcgcagcctgctggccatcggcttcggg ctcgtggtggccgcctcgcacttgctggtcacggctacgttggtccccgccaagcgccca cgtctctggagaacgctgggtgccaacgctctgctcttcctcggtgtgaacgtgtatggc gtcttcgtgaggatcctggctgagcgcgcccagaggaaggccttcctgcaggcccggaac tgcattgaggaccggctgaggctggaggacgagaatgagaagcaggagcggctgctcatg agcctcctgcctcggaatgttgccatggagatgaaggaggacttcctgaagccccctgag aggattttccacaagatttacatccagcggcatgacaacgtgagcatcctctttgcagac atcgtgggcttcacaggcttggcgtcacagtgcacggcccaggagctggtgaaactcctc aacgagctcttcgggaagtttgacgagctggccacagagaaccactgccgccgcatcaag atcctgggagattgctactactgcgtgtctggcctcactcagcccaagactgaccacgcc cactgctgtgtggagatgggcctggacatgatcgacaccatcacgtccgtggctgaggcc actgaggtggacttgaacatgcgtgtggggctgcacaccggcagggtcctctgcggggtc ctgggcctgcgtaagtggcagtatgatgtgtggtccaacgacgtgaccctggccaacgtc atggaggccgccggcctgcctgggaaggttcacatcacaaagaccaccctggcgtgcctg aatggtgactatgaggtggagccgggacacggacacgagaggaacagttttctgaaaact cataacattgagaccttttttattgtgccctcgcatcggcgaaagatatttccagggctg attctctcagacataaaaccggccaagaggatgaagttcaagaccgtgtgctacctgctg gtgcagctcatgcactgccggaagatgttcaaggccgagatccctttctccaacgtcatg acctgtgaggacgacgacaagcggagggcactgagaacagcctcggaaaaactcagaaac cgctcgtctttctctacaaacgttgtccaaaccacccccggcacacgtgtcaacaggtac atcggccgcctcctggaagcccgccagatggagctggagatggcagacctgaacttcttc accctgaagtacaagcaagctgagcgagagcgaaagtaccaccagcttcaggacgagtat ttcaccagcgccgtggttctggctctcattctggccgccttattcggccttgtctacctt ctaataatcccacagagtgtggctgtcctgctcctgctggtgttctgcatctgcttcctg gtggcctgtgtcctgtacctacacatcacccgggtccagtgttttccagggtgcctgacc atccagatccgcaccgtcttgtgcatcttcatcgtggtcttaatctactctgtggcccaa ggctgtgtggtgggctgcctgccttggtcctggagctccagtcccaacgggtccctggtg gtcctgtcttctgggggccgggacccagtgctgcctgtcccgccctgcgagtctgcgccc cacgccctgctgtgcggcctcgtgggcaccctcccgctggccatattcctgcgggtctcc tccttgccaaaaatgatcctgctcgccgtgctcaccacctcctacatcctcgtcctggag ctcagcgggtacacgaaggccatgggggccggtgccatctcagggcgcagcttcgagccg atcgtggccatcctgctgttctcatgcacgctggccctgcacgcccggcaggtggatgtc aagctgcggctggactacctctgggcggcccaggcagaggaggagcgggatgacatggag aaagtgaagctggacaacaagaggattctcttcaacctcctgccagcccacgttgcccag cacttcctaatgtccaaccctcgcaacatggacctgtattaccagtcatactcgcaggtg ggggtcatgtttgcatccatccccaacttcaatgacttctacatcgagctggatggcaac aacatgggggtggaatgtctacgccttctgaatgagatcatcgctgactttgatgagctc atggacaaagacttttacaaggacctagagaagatcaagaccattgggagcacgtacatg gctgctgtggggctggcgcccactgctgggaccaaggctaagaagtgcatctcctcccac ctcagcacgttggcagattttgccatcgagatgtttgatgtcctggatgagatcaactac cagtcttataacgactttgtgctccgtgttggcatcaatgttggccccgtggtggctgga gtgatcggggctcgcaggccgcagtatgacatttgggggaacacggtcaatgtggccagt cggatggacagtactggcgtccagggcaggatccaggtcacagaggaagttcaccggctg ctgcggcggggttcctaccgcttcgtgtgccgaggcaaagtcagtgtcaagggcaagggt gagatgctgacatacttcctggaaggcaggaccgatggaaatggctcccaaacnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnncggaagagctggcctccagaccagactggct gcgggtcaccccccggtacctcctgcagccggcctcccagttggagctgggccaggggct ctgcagggctcggggcttgccccaggccccccaggccaacacctgccccctggagcctct gggaaggaggcttag

Bos mutus (wild yak): 102272964 Help Entry 102272964         CDS       T02919                                  Gene name ADCY8 Definition (RefSeq) adenylate cyclase 8   KO K08048   adenylate cyclase 8 [EC:4.6.1.1] Organism bom  Bos mutus (wild yak) Pathway bom00230   Purine metabolism bom01100   Metabolic pathways bom01522   Endocrine resistance bom04015   Rap1 signaling pathway bom04020   Calcium signaling pathway bom04022   cGMP-PKG signaling pathway bom04024   cAMP signaling pathway bom04062   Chemokine signaling pathway bom04072   Phospholipase D signaling pathway bom04114   Oocyte meiosis bom04211   Longevity regulating pathway bom04213   Longevity regulating pathway - multiple species bom04261   Adrenergic signaling in cardiomyocytes bom04270   Vascular smooth muscle contraction bom04371   Apelin signaling pathway bom04540   Gap junction bom04611   Platelet activation bom04713   Circadian entrainment bom04714   Thermogenesis bom04720   Long-term potentiation bom04723   Retrograde endocannabinoid signaling bom04724   Glutamatergic synapse bom04725   Cholinergic synapse bom04727   GABAergic synapse bom04742   Taste transduction bom04750   Inflammatory mediator regulation of TRP channels bom04911   Insulin secretion bom04912   GnRH signaling pathway bom04913   Ovarian steroidogenesis bom04914   Progesterone-mediated oocyte maturation bom04915   Estrogen signaling pathway bom04916   Melanogenesis bom04918   Thyroid hormone synthesis bom04921   Oxytocin signaling pathway bom04923   Regulation of lipolysis in adipocytes bom04925   Aldosterone synthesis and secretion bom04926   Relaxin signaling pathway bom04927   Cortisol synthesis and secretion bom04928   Parathyroid hormone synthesis, secretion and action bom04934   Cushing syndrome bom04935   Growth hormone synthesis, secretion and action bom04970   Salivary secretion bom04971   Gastric acid secretion bom04972   Pancreatic secretion bom04976   Bile secretion bom05032   Morphine addiction bom05163   Human cytomegalovirus infection bom05166   Human T-cell leukemia virus 1 infection bom05200   Pathways in cancer bom05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:bom00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     102272964 (ADCY8)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     102272964 (ADCY8)    04371 Apelin signaling pathway     102272964 (ADCY8)    04020 Calcium signaling pathway     102272964 (ADCY8)    04072 Phospholipase D signaling pathway     102272964 (ADCY8)    04024 cAMP signaling pathway     102272964 (ADCY8)    04022 cGMP-PKG signaling pathway     102272964 (ADCY8)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     102272964 (ADCY8)   09144 Cellular community - eukaryotes    04540 Gap junction     102272964 (ADCY8)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     102272964 (ADCY8)    04062 Chemokine signaling pathway     102272964 (ADCY8)   09152 Endocrine system    04911 Insulin secretion     102272964 (ADCY8)    04923 Regulation of lipolysis in adipocytes     102272964 (ADCY8)    04912 GnRH signaling pathway     102272964 (ADCY8)    04913 Ovarian steroidogenesis     102272964 (ADCY8)    04915 Estrogen signaling pathway     102272964 (ADCY8)    04914 Progesterone-mediated oocyte maturation     102272964 (ADCY8)    04921 Oxytocin signaling pathway     102272964 (ADCY8)    04926 Relaxin signaling pathway     102272964 (ADCY8)    04935 Growth hormone synthesis, secretion and action     102272964 (ADCY8)    04918 Thyroid hormone synthesis     102272964 (ADCY8)    04928 Parathyroid hormone synthesis, secretion and action     102272964 (ADCY8)    04916 Melanogenesis     102272964 (ADCY8)    04925 Aldosterone synthesis and secretion     102272964 (ADCY8)    04927 Cortisol synthesis and secretion     102272964 (ADCY8)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     102272964 (ADCY8)    04270 Vascular smooth muscle contraction     102272964 (ADCY8)   09154 Digestive system    04970 Salivary secretion     102272964 (ADCY8)    04971 Gastric acid secretion     102272964 (ADCY8)    04972 Pancreatic secretion     102272964 (ADCY8)    04976 Bile secretion     102272964 (ADCY8)   09156 Nervous system    04724 Glutamatergic synapse     102272964 (ADCY8)    04727 GABAergic synapse     102272964 (ADCY8)    04725 Cholinergic synapse     102272964 (ADCY8)    04720 Long-term potentiation     102272964 (ADCY8)    04723 Retrograde endocannabinoid signaling     102272964 (ADCY8)   09157 Sensory system    04742 Taste transduction     102272964 (ADCY8)    04750 Inflammatory mediator regulation of TRP channels     102272964 (ADCY8)   09149 Aging    04211 Longevity regulating pathway     102272964 (ADCY8)    04213 Longevity regulating pathway - multiple species     102272964 (ADCY8)   09159 Environmental adaptation    04713 Circadian entrainment     102272964 (ADCY8)    04714 Thermogenesis     102272964 (ADCY8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102272964 (ADCY8)   09165 Substance dependence    05032 Morphine addiction     102272964 (ADCY8)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     102272964 (ADCY8)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     102272964 (ADCY8)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102272964 (ADCY8)    05163 Human cytomegalovirus infection     102272964 (ADCY8)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     102272964 (ADCY8) Enzymes [BR:bom01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      102272964 (ADCY8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc DUF1053 AC_N TBK1_ULD Motif Other DBs NCBI-GeneID:  102272964 NCBI-ProteinID:  XP_005900059 LinkDB All DBs Position Un AA seq 1067 aa AA seqDB search MNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGFFTGIEVVICALVVVRKDTTSHTYLQY SGVVTWVAMTTQILAAGLGYGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLGTSLMQV VLQAVIPRLAVISINQVVAQAVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVEARLRLE TENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFADVKGFT NLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQDHAHCCVE MGLSMIKTIRYVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKLESGG IPGRIHISKATLDCLNGDYNVEEGHGKERNEFLRKHNIETYLIKQPEESLLSLPEDIVKE SVSSSDRRNSGATFTEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHLAQALHVQSGP EEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLVCAFIVLL FITAIQSLLPSSRVMPMAVQFSILIMLHSALVLITTAEDYKCLPLVLRKTCCWINETYLA RNVIIFASILINFLGAILNILWCDFDKSIPLKNLTFNSSAVFTDICSYPEYFVFTGVLAM VTCAVFLRLNSVLKLAVLLIMIAIYALLTETIYAGLFLRYDNLNHSGEDFLGTKEASLLL MAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSHVARHFL EKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFDELLGE DRFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWGHLCALADFSLALTESIQEINKHSFNN FELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPEETYLILKDQG FAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPFILPPRRLPGQYSLAAVVLGLVQSLN RQRQKQLLNENNNTGIIKGHYNRRTLLTPSGPEPGAPAEGADKSELP NT seq 3204 nt NT seq  +upstreamnt  +downstreamnt atgaacgtgctggacgtgctgaccaaactcaccctcctggttctccacttgagcctggcc tcggcccccatggacccgctcaagggcatcctgctgggcttcttcaccggcatagaggtg gtgatctgcgccctggtggtggtcagaaaggacaccacctcgcacacatacctgcagtac agcggtgtggtcacttgggtggccatgaccacccagatcttagcagcagggctcggctat gggctcctgggagacggcatcggctacgtgctcttcaccctttttgccacctacagcatg ctgccgctgccgctcacctgggccatcctggccggcctaggcacctctttgatgcaggtg gtcctccaagcggtcatccccaggctggcggtcatttccatcaatcaggttgtggcccag gcagtgttattcatgtgtatgaacacagctggaatcttcatcagttacctgtcagaccgg gcccagcgccaagccttcctggagacacggaggtgtgtggaggccaggctgcgcctggag acggaaaaccaaagacaggagcgacttgtgctgtccgtgcttcctcgttttgttgtcctg gagatgatcaatgacatgaccaacgtggaagacgagcacctacagcatcagttccaccgg atctacatccatcgctacgagaatgtcagtattctttttgcagatgttaaaggatttacc aacctctccacgaccttgtctgctcaggagctggtcaggatgctcaacgagctctttgcc agatttgatcgactggcccatgagcatcactgccttcgtattaaaatcctgggggactgc tactactgcgtttcaggacttcctgagccccgccaggaccacgcccactgctgtgttgaa atgggcctcagcatgatcaaaactatcaggtatgtgcgatcaaggacaaagcacgatgtt gacatgcggattggaatccactcgggctcggtgctgtgcggcgtgttgggtcttcggaag tggcagtttgatgtctggtcttgggatgtggacatcgcgaacaaacttgaatctggagga atccccgggcggattcacatttccaaagccacgctggactgcctcaacggtgactataat gtggaagagggtcatggtaaagagaggaatgaattcttgaggaagcataatatagagacc tatttaattaagcagcctgaggagagtctgctgtctttgcccgaagacatcgtcaaggag tctgtgagctcctcagacaggagaaacagcggggcgacgttcacagagggatcttggagc cctgaactgcccttcgataacatagtggggaaacagaacactctggctgccctaacaaga aattcaataaatctacttccaaaccatcttgcacaagctttgcatgtccagtctgggcct gaggaaattaacaagagaatagaacataccatcgacttgcggagtggtgataaattgaga agagagcatatcaagccattctcactgatgtttaaagactccagcctggagcacaagtat tctcaaatgagggatgaagtattcaaatcaaacttggtctgtgcgtttatcgttcttcta tttatcacggcaatacaaagcttgcttccttcttcaagggtgatgcccatggccgtccag ttttccatcctgatcatgctgcactcagctctggtcctcatcactacggcagaggattac aagtgtttgcccctggtcctccggaaaacctgctgttggattaacgagacctatttggcc aggaacgtcatcatctttgcatccatcttgattaatttcctgggcgccatcctaaatatc ctgtggtgtgattttgacaagtcgatacccttgaagaacctgactttcaattcctcagct gtgtttacagatatctgctcctacccagagtactttgtcttcacgggggtgctggccatg gtgacctgtgcggttttcctccgactcaactctgtccttaagctggctgtgctcctgatc atgattgccatctacgccctgctgaccgagaccatctatgcaggcctcttcctgcgctat gacaacctgaaccacagcggagaagatttcctggggaccaaggaagcgtcactgctgcta atggccatgtttcttcttgccgttttctaccatggacagcagctggagtacacagcccgc ctggacttcctgtggcgagtccaggccaaagaggagatcaacgagatgaaggagctgagg gagcacaatgagaacatgctgcggaacatcctgcccagccacgtggcccgccacttcctg gagaaggatcgggacaatgaggagctgtattctcaatcctatgacgccgtcggggtgatg tttgcctccatcccggggtttgcagacttttactctcagaccgaaatgaacaaccaagga gtggagtgcctccgcctactgaatgagatcattgctgacttcgatgagctgctcggtgaa gaccggtttcaagacattgaaaagattaagaccattggtagtacctacatggccgtgtca ggcctgtcacctgaaaagcagcaatgcgaggataagtgggggcatttgtgcgccctggcc gacttctccctcgccctgactgaaagcatccaggagatcaacaagcattccttcaacaat ttcgagctccggattggcatcagccacggctcagtggtagccggtgtcatcggcgctaag aaaccacagtacgacatttggggcaaaaccgtgaacctggcgagtcggatggacagcaca ggggtcagcggcaggatccaggtcccggaggagacctacctcatcctgaaggaccagggc tttgcctttgactaccgaggggagatctatgtgaagggcatcagcgaacaggaagggaaa atcaaaacgtactttctcctgggaagagtccagcccaaccccttcatcctgccccccagg agactgcccgggcagtactccttggccgcagtcgtcctgggcctcgtccagtctctcaac aggcagaggcagaagcagctgctgaacgagaacaacaacacgggcattatcaagggccac tacaaccggcggactttgctgacacccagcgggcccgagccgggagccccagccgaaggc gccgacaagtccgagttgccataa

Bos mutus (wild yak): 102274117 Help Entry 102274117         CDS       T02919                                  Gene name ADCY2 Definition (RefSeq) adenylate cyclase 2   KO K08042   adenylate cyclase 2 [EC:4.6.1.1] Organism bom  Bos mutus (wild yak) Pathway bom00230   Purine metabolism bom01100   Metabolic pathways bom01522   Endocrine resistance bom04015   Rap1 signaling pathway bom04020   Calcium signaling pathway bom04022   cGMP-PKG signaling pathway bom04024   cAMP signaling pathway bom04062   Chemokine signaling pathway bom04072   Phospholipase D signaling pathway bom04114   Oocyte meiosis bom04211   Longevity regulating pathway bom04213   Longevity regulating pathway - multiple species bom04261   Adrenergic signaling in cardiomyocytes bom04270   Vascular smooth muscle contraction bom04371   Apelin signaling pathway bom04540   Gap junction bom04611   Platelet activation bom04713   Circadian entrainment bom04714   Thermogenesis bom04723   Retrograde endocannabinoid signaling bom04724   Glutamatergic synapse bom04725   Cholinergic synapse bom04727   GABAergic synapse bom04750   Inflammatory mediator regulation of TRP channels bom04911   Insulin secretion bom04912   GnRH signaling pathway bom04913   Ovarian steroidogenesis bom04914   Progesterone-mediated oocyte maturation bom04915   Estrogen signaling pathway bom04916   Melanogenesis bom04918   Thyroid hormone synthesis bom04921   Oxytocin signaling pathway bom04922   Glucagon signaling pathway bom04923   Regulation of lipolysis in adipocytes bom04925   Aldosterone synthesis and secretion bom04926   Relaxin signaling pathway bom04927   Cortisol synthesis and secretion bom04928   Parathyroid hormone synthesis, secretion and action bom04934   Cushing syndrome bom04935   Growth hormone synthesis, secretion and action bom04970   Salivary secretion bom04971   Gastric acid secretion bom04972   Pancreatic secretion bom04976   Bile secretion bom05032   Morphine addiction bom05163   Human cytomegalovirus infection bom05166   Human T-cell leukemia virus 1 infection bom05200   Pathways in cancer bom05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:bom00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     102274117 (ADCY2)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     102274117 (ADCY2)    04371 Apelin signaling pathway     102274117 (ADCY2)    04020 Calcium signaling pathway     102274117 (ADCY2)    04072 Phospholipase D signaling pathway     102274117 (ADCY2)    04024 cAMP signaling pathway     102274117 (ADCY2)    04022 cGMP-PKG signaling pathway     102274117 (ADCY2)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     102274117 (ADCY2)   09144 Cellular community - eukaryotes    04540 Gap junction     102274117 (ADCY2)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     102274117 (ADCY2)    04062 Chemokine signaling pathway     102274117 (ADCY2)   09152 Endocrine system    04911 Insulin secretion     102274117 (ADCY2)    04922 Glucagon signaling pathway     102274117 (ADCY2)    04923 Regulation of lipolysis in adipocytes     102274117 (ADCY2)    04912 GnRH signaling pathway     102274117 (ADCY2)    04913 Ovarian steroidogenesis     102274117 (ADCY2)    04915 Estrogen signaling pathway     102274117 (ADCY2)    04914 Progesterone-mediated oocyte maturation     102274117 (ADCY2)    04921 Oxytocin signaling pathway     102274117 (ADCY2)    04926 Relaxin signaling pathway     102274117 (ADCY2)    04935 Growth hormone synthesis, secretion and action     102274117 (ADCY2)    04918 Thyroid hormone synthesis     102274117 (ADCY2)    04928 Parathyroid hormone synthesis, secretion and action     102274117 (ADCY2)    04916 Melanogenesis     102274117 (ADCY2)    04925 Aldosterone synthesis and secretion     102274117 (ADCY2)    04927 Cortisol synthesis and secretion     102274117 (ADCY2)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     102274117 (ADCY2)    04270 Vascular smooth muscle contraction     102274117 (ADCY2)   09154 Digestive system    04970 Salivary secretion     102274117 (ADCY2)    04971 Gastric acid secretion     102274117 (ADCY2)    04972 Pancreatic secretion     102274117 (ADCY2)    04976 Bile secretion     102274117 (ADCY2)   09156 Nervous system    04724 Glutamatergic synapse     102274117 (ADCY2)    04727 GABAergic synapse     102274117 (ADCY2)    04725 Cholinergic synapse     102274117 (ADCY2)    04723 Retrograde endocannabinoid signaling     102274117 (ADCY2)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     102274117 (ADCY2)   09149 Aging    04211 Longevity regulating pathway     102274117 (ADCY2)    04213 Longevity regulating pathway - multiple species     102274117 (ADCY2)   09159 Environmental adaptation    04713 Circadian entrainment     102274117 (ADCY2)    04714 Thermogenesis     102274117 (ADCY2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102274117 (ADCY2)   09165 Substance dependence    05032 Morphine addiction     102274117 (ADCY2)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     102274117 (ADCY2)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     102274117 (ADCY2)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102274117 (ADCY2)    05163 Human cytomegalovirus infection     102274117 (ADCY2)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     102274117 (ADCY2) Enzymes [BR:bom01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      102274117 (ADCY2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc DUF1053 AC_N Motif Other DBs NCBI-GeneID:  102274117 NCBI-ProteinID:  XP_005905194 LinkDB All DBs Position Un AA seq 913 aa AA seqDB search LPTWLQERLLLSLLPAHIAMEMKAEIIQRLQGPKAGQMENTNNFHNLYVKRHTNVSILYA DIVGFTRLASDCSPGELVHMLNELFGKFDQIAKENECMRIKILGDCYYCVSGLPISLPNH AKNCVKMGLDMCEAIKKVRDATGVDINMRVGVHSGNVLCGVIGLQKWQYDVWSHDVTLAN HMEAGGVPGRVHISSVTLQHLNGAYKVEEGDGDIRDPYLKQHLVKTYFVINPKGERRSPQ HLFRPRHTLDGAKMRASVRMTRYLESWGAAKPFAHLHHRDSMTTENGKISTTDVPMGQHN FQNRTLRTKSQKKRFEEELNERMIQAIDGINAQKQWLKSEDIQRISLLFYNKIIEKEYRA TALPAFKYYVTCACLIFFCIFIVQVLVLPKTSILGISFGAAFLSLAFILFVCFAGQLLQC SKKASASLLWLLKSSGIIANRPWPRISLTVITTAIILTMAVFNMFFLSDSEETILPTANA SNTSLSGASNQAAILRAQNLFFLPYFIYSCILGLISCSVFLRVNYELKMLIMMAALVGYN TIFLHTHAPLLDDYSQVLFERPGIWKDLKTMGSVSLFIFFITLLVLGRQNEYYCRLDFLW KNKFKKEREEIETMENLNRVLLENVLPAHVAEHFLARSLKNEGQVNAGSSEGRTSCHAVG IQSVLAVVLCILVIITIPQRVTSADVSRCQGNARTLLMVLGGVLPIMHCAHIGAWPFRLC QAIQGPRGAGTSGKADPRPPRTSSRAHLLSKPKFSGVEKIKTIGSTYMAATGLSAVPSQE HAQEPERQYMHIGTMVEFAFALVGKLDAINKHSFNDFKLRVGINHGPVIAGVIGAQKPQY DIWGNTVNVASRMDSTGVLDKIQVTEETSVILQTLGYTCTCRGIINVKGKGDLKTYFVNT EMSRSLSQSNLTS NT seq 2742 nt NT seq  +upstreamnt  +downstreamnt cttccaacctggcttcaggagcggctgctgctgtccctgctgccggcacacatagccatg gagatgaaagcggagatcatccagaggctgcagggccccaaagccggccagatggagaac accaacaacttccacaacctctacgtcaagcggcacaccaacgtcagtatcctctatgcg gacattgttgggttcacccgtctggccagtgactgctcccctggagagctcgtccatatg ctgaatgaactctttggaaagttcgatcaaattgcaaaggagaatgaatgcatgagaata aaaattttaggagactgctactactgtgtgtccggactgcctatatctctccctaaccat gccaagaattgtgtgaaaatgggactggatatgtgtgaagccataaagaaagtgagggac gccaccggagtggacatcaacatgcgcgtgggagtgcattctgggaacgtgctgtgcggc gtgatcgggctgcagaagtggcagtacgacgtgtggtcacatgacgtcaccctggccaac cacatggaagctggaggggtccctggacgtgttcacatttcttctgttaccctgcaacac ttgaatggagcttacaaagtggaagaaggcgatggtgacatcagagacccgtatttaaag caacatttggtgaaaacttactttgtaatcaaccccaagggagagcggcggagccctcag cacctctttaggcctcgacacacccttgacggagcgaagatgagggcttctgtccgcatg acccggtacctggagtcctggggggcggccaagccctttgcacacctgcatcacagagac agcatgactacggagaacggcaagatcagcaccacggatgtaccaatgggtcagcataat tttcaaaatcgcaccttaagaaccaagtcacaaaagaaaagatttgaagaggaattaaat gaaaggatgattcaagcaattgatggaatcaatgcacaaaagcaatggctcaagtccgaa gacattcagagaatctcattgcttttctacaataaaataatagaaaaagaataccgagcc accgcactgccggccttcaagtattacgtgacttgcgcttgcctgatcttcttctgcatc tttatcgtgcaggttctggtcttacccaaaacgtccattctcggaatttcctttggagcg gcgtttctctcacttgcctttatccttttcgtctgctttgctggacagcttttgcaatgc agcaagaaagcatctgcttctctcctgtggcttttaaagtcatcgggcatcatcgccaac cggccctggcctcggatctccctgacggtcatcaccacggccatcatattgaccatggcc gtgttcaatatgtttttcctgagtgactcagaggaaacaattcttccgactgccaacgcg tccaacacaagtctttctggcgcaagtaaccaggcagcaattctgcgtgcgcaaaatttg tttttcctgccgtactttatatacagctgcatccttgggctgatctcctgttccgtcttc ctgcgtgtgaattacgagctgaagatgctgatcatgatggcagccttggtgggctacaac accatcttcctccacactcacgctcccctcctggacgactacagccaggtcctgttcgag agaccaggcatttggaaagacctaaagaccatgggctcagtatctctctttatatttttc atcacactgcttgttctgggaagacagaatgaatattactgtaggttagacttcttatgg aagaacaagttcaaaaaagagcgggaggagatagaaaccatggagaacttgaaccgagtg ctgctggagaacgtgcttcctgcgcacgtggctgagcacttcctggcgcggagcctgaag aacgaggggcaagttaatgctggtagttcagaggggcgcacatcctgccacgcagtgggc attcagtcagtgctggcggttgtcctgtgcattcttgtcatcatcaccattccccagagg gtcacttcggctgatgtcagcagatgccagggaaacgcaagaactctcctcatggttctt ggtggagtgcttcccatcatgcactgcgcccacattggcgcctggccattccgcctgtgt caggccatccaagggccccgaggagccggcaccagtggaaaagcagatccccggcccccc aggaccagctcccgcgcccacctgctctccaagccgaagttcagtggtgttgaaaagatc aagaccatcggcagcacgtacatggcagcgacaggtctgagcgcggtgcccagccaggag cacgcccaggagccggagaggcagtacatgcacattggcaccatggtggagtttgcattt gccctggtggggaagctggatgccatcaacaagcactccttcaatgacttcaagttacga gtaggtattaaccatggccctgtcatagccggtgtgattggagctcagaagccgcagtat gacatctggggcaacaccgtcaatgtggccagcaggatggacagcaccggagtcctggac aaaatccaggtgacagaggagacgagcgtcatcctacagaccctaggctacacgtgcacg tgtcggggaatcatcaacgtgaaaggaaagggggacctgaagacctacttcgtcaacacg gagatgtcacggtccctttctcagagcaacctgacctcctga

Bos mutus (wild yak): 102276460 Help Entry 102276460         CDS       T02919                                  Gene name ADCY5 Definition (RefSeq) adenylate cyclase 5   KO K08045   adenylate cyclase 5 [EC:4.6.1.1] Organism bom  Bos mutus (wild yak) Pathway bom00230   Purine metabolism bom01100   Metabolic pathways bom01522   Endocrine resistance bom04015   Rap1 signaling pathway bom04022   cGMP-PKG signaling pathway bom04024   cAMP signaling pathway bom04062   Chemokine signaling pathway bom04072   Phospholipase D signaling pathway bom04114   Oocyte meiosis bom04211   Longevity regulating pathway bom04213   Longevity regulating pathway - multiple species bom04261   Adrenergic signaling in cardiomyocytes bom04270   Vascular smooth muscle contraction bom04371   Apelin signaling pathway bom04540   Gap junction bom04611   Platelet activation bom04713   Circadian entrainment bom04714   Thermogenesis bom04723   Retrograde endocannabinoid signaling bom04724   Glutamatergic synapse bom04725   Cholinergic synapse bom04726   Serotonergic synapse bom04727   GABAergic synapse bom04728   Dopaminergic synapse bom04750   Inflammatory mediator regulation of TRP channels bom04911   Insulin secretion bom04912   GnRH signaling pathway bom04913   Ovarian steroidogenesis bom04914   Progesterone-mediated oocyte maturation bom04915   Estrogen signaling pathway bom04916   Melanogenesis bom04918   Thyroid hormone synthesis bom04921   Oxytocin signaling pathway bom04923   Regulation of lipolysis in adipocytes bom04924   Renin secretion bom04925   Aldosterone synthesis and secretion bom04926   Relaxin signaling pathway bom04927   Cortisol synthesis and secretion bom04928   Parathyroid hormone synthesis, secretion and action bom04934   Cushing syndrome bom04935   Growth hormone synthesis, secretion and action bom04970   Salivary secretion bom04971   Gastric acid secretion bom04972   Pancreatic secretion bom04976   Bile secretion bom05012   Parkinson disease bom05030   Cocaine addiction bom05031   Amphetamine addiction bom05032   Morphine addiction bom05034   Alcoholism bom05163   Human cytomegalovirus infection bom05166   Human T-cell leukemia virus 1 infection bom05200   Pathways in cancer bom05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:bom00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     102276460 (ADCY5)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     102276460 (ADCY5)    04371 Apelin signaling pathway     102276460 (ADCY5)    04072 Phospholipase D signaling pathway     102276460 (ADCY5)    04024 cAMP signaling pathway     102276460 (ADCY5)    04022 cGMP-PKG signaling pathway     102276460 (ADCY5)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     102276460 (ADCY5)   09144 Cellular community - eukaryotes    04540 Gap junction     102276460 (ADCY5)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     102276460 (ADCY5)    04062 Chemokine signaling pathway     102276460 (ADCY5)   09152 Endocrine system    04911 Insulin secretion     102276460 (ADCY5)    04923 Regulation of lipolysis in adipocytes     102276460 (ADCY5)    04912 GnRH signaling pathway     102276460 (ADCY5)    04913 Ovarian steroidogenesis     102276460 (ADCY5)    04915 Estrogen signaling pathway     102276460 (ADCY5)    04914 Progesterone-mediated oocyte maturation     102276460 (ADCY5)    04921 Oxytocin signaling pathway     102276460 (ADCY5)    04926 Relaxin signaling pathway     102276460 (ADCY5)    04935 Growth hormone synthesis, secretion and action     102276460 (ADCY5)    04918 Thyroid hormone synthesis     102276460 (ADCY5)    04928 Parathyroid hormone synthesis, secretion and action     102276460 (ADCY5)    04916 Melanogenesis     102276460 (ADCY5)    04924 Renin secretion     102276460 (ADCY5)    04925 Aldosterone synthesis and secretion     102276460 (ADCY5)    04927 Cortisol synthesis and secretion     102276460 (ADCY5)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     102276460 (ADCY5)    04270 Vascular smooth muscle contraction     102276460 (ADCY5)   09154 Digestive system    04970 Salivary secretion     102276460 (ADCY5)    04971 Gastric acid secretion     102276460 (ADCY5)    04972 Pancreatic secretion     102276460 (ADCY5)    04976 Bile secretion     102276460 (ADCY5)   09156 Nervous system    04724 Glutamatergic synapse     102276460 (ADCY5)    04727 GABAergic synapse     102276460 (ADCY5)    04725 Cholinergic synapse     102276460 (ADCY5)    04728 Dopaminergic synapse     102276460 (ADCY5)    04726 Serotonergic synapse     102276460 (ADCY5)    04723 Retrograde endocannabinoid signaling     102276460 (ADCY5)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     102276460 (ADCY5)   09149 Aging    04211 Longevity regulating pathway     102276460 (ADCY5)    04213 Longevity regulating pathway - multiple species     102276460 (ADCY5)   09159 Environmental adaptation    04713 Circadian entrainment     102276460 (ADCY5)    04714 Thermogenesis     102276460 (ADCY5)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102276460 (ADCY5)   09164 Neurodegenerative disease    05012 Parkinson disease     102276460 (ADCY5)   09165 Substance dependence    05030 Cocaine addiction     102276460 (ADCY5)    05031 Amphetamine addiction     102276460 (ADCY5)    05032 Morphine addiction     102276460 (ADCY5)    05034 Alcoholism     102276460 (ADCY5)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     102276460 (ADCY5)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     102276460 (ADCY5)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102276460 (ADCY5)    05163 Human cytomegalovirus infection     102276460 (ADCY5)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     102276460 (ADCY5) Enzymes [BR:bom01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      102276460 (ADCY5) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  AC_N Guanylate_cyc DUF1053 HNOBA DUF2339 TBK1_ULD PEN-2 Motif Other DBs NCBI-GeneID:  102276460 NCBI-ProteinID:  XP_005893490 LinkDB All DBs Position Un AA seq 1082 aa AA seqDB search VEEDEGSGDGGSSAGSGAGPGAVLSLGACCLALLQIFRSKKFPSDKLERLYQRYFFRLNQ SSLTMLMAVLVLVCLVMLAFHAARPPLQLPYLAVLAAAVGVILVMAVLCNRAAFHQDHMG LACYALIAVVLAVQVVGLLLPQPRSASEGIWWTVFFIYTIYTLLPVRMRAAVLSGVLLSA LHLAIALRTNAQDQFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQAFQETRECIQARL HSQRENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEGFT SLASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVE MGMDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGG KAGRIHITKATLNYLNGDYEVEPGCGGERNAYLKEHSIETFLILRCTQKRKEEKAMIAKM NRQRTNSIGHNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDPKDKSRVFSSAPKDXXDEF LGRAIDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVACASLVFLFICFVQ ITIVPHSVFMLSFYLTCFLLLTLVVFVSVIYSCVKLFPAPLQTLSRKIVRSKMNSTLVGV FTITLVFLSAFVNMFTCNSKDLFGCLGDEHNISASQVNACHVVESAVNYSLGDEQGFCGS SWPNCNFPEYFTYSVLLSLLACSVFLQISCIGKLVLMLAIELIYVLVVEVPGVTLFDNAD LLVTANAIDFSNNGTSQCPEHPTKVALKVVTPIIISVFVLALYLHAQQVESTARLDFLWK LQATEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIAN FSEFYVELEANNEGVECLRLLNEIIADFDEIISEDRFRQLEKIKTIGSTYMAASGLNDST YDKVGKTHIKALADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIW GNTVNVASRMDSTGVPDRIQVTTDMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGGPP PS NT seq 3249 nt NT seq  +upstreamnt  +downstreamnt gtcgaggaagacgaagggtccggggatgggggcagctcggcaggctcgggcgcggggcct ggcgcggtgctgtcgctgggcgcctgctgcctggcactgctgcagatattccgctctaag aagttcccatcggacaagctggagcggctgtaccagcgctacttcttccgtctgaaccag agcagcctcacaatgctcatggctgtgctggtgctcgtgtgcctagtcatgttggccttc cacgcggcacggcccccgctgcagctgccctacctggccgtcctagcggccgccgtgggt gtgatcctcgttatggccgtgctctgcaaccgcgccgccttccaccaggaccacatgggc ctggcctgctacgcgcttatcgccgtggtgctggccgtccaggtggtgggcctgttgctg ccccagccgcgcagtgcctccgagggcatctggtggactgtgtttttcatctatacgatc tacacgctcctgcccgtgcgcatgcgggctgcggtactcagcggggtgctcctgtccgcc ctccacctggccatcgccctgcgcaccaacgcccaggatcagttcctgctcaagcagctc gtctccaacgtcctcattttctcctgcaccaacattgtgggtgtgtgcacccactacccg gctgaggtctcgcagaggcaggccttccaggagacccgggagtgcatccaggcacggctc cactcacagcgggagaaccagcagcaggagcggctcctgctgtctgtccttccccgtcac gttgccatggagatgaaagccgacatcaacgccaaacaggaggatatgatgttccataag atttacatccagaaacatgacaacgtgagcatcctgtttgctgacatcgagggtttcacc agcctggcatcccagtgcactgcccaggagctggtcatgaccctcaacgagctcttcgcc cgcttcgacaagctggctgcggagaatcactgtttacgtattaagatcctgggagattgt tattactgtgtctcagggctgcctgaagccagggctgaccacgcccactgctgcgtggag atgggcatggacatgatcgaggccatctcgctggtccgggaggtgacaggtgtgaacgtg aacatgcgtgtgggaattcacagcgggagagtgcactgcggtgtcctcggcctcaggaag tggcagttcgatgtctggtctaacgatgtcacactggccaaccacatggaggctggaggc aaggcgggacgcatccacatcaccaaggccactctcaactacttgaatggtgactacgaa gtggagccaggctgtgggggcgagcgcaacgcctacctcaaggagcacagtatcgagacc tttctcatcctgcgctgcacccagaagcggaaagaagagaaggccatgattgccaagatg aaccgtcagagaaccaactccatcgggcacaacccgccccactggggggccgagcgcccc ttctataaccacctggggggcaaccaggtgtccaaggagatgaagcggatgggctttgaa gaccccaaggacaaaagtagagtgtttagttcagcaccaaaagatnnnnnggatgaattt ctgggccgtgccattgatgccaggagcatcgacaggctgcgatctgaacatgttcgcaag ttcctcttgaccttcagggagcctgacttagagaagaagtactccaagcaggtggatgac cgatttggtgcctacgtggcctgtgcctcgctcgtcttcctcttcatctgctttgtccag atcaccattgtgccccactccgtgttcatgttgagtttctacctgacctgtttcctgctg ctgaccttggtggtgtttgtgtccgtgatctattcttgcgtgaagctcttcccagccccg ctgcagacgctctccaggaagatcgtgcggtccaagatgaacagcaccctggtgggggtg ttcaccatcaccctcgtgttcctgtcggctttcgtcaacatgttcacgtgcaactccaag gacctgtttggctgcctgggggacgagcacaacatcagtgccagtcaggtcaatgcatgc cacgtggtggagtcggccgtcaactacagtctgggtgacgagcagggcttctgcggcagc tcctggcccaactgcaacttccccgagtacttcacctatagcgtgctgctcagcctgctg gcctgctccgtgttcctgcagatcagctgcatcgggaagctggtgctcatgctggccatc gagctcatctacgtgctcgtcgttgaggtgcccggtgtcacgctctttgacaatgccgac ctactggtcacggccaacgccatagacttcagcaacaacgggacctcccagtgccctgag catccaaccaaggtggcgctgaaggtggtgacgcccatcatcatctccgtcttcgtgctg gccctgtacctgcatgcccagcaggtggagtccactgcccgcctcgacttcctctggaaa cttcaggccacggaggagaaggaggagatggaggagctgcaggcctacaaccggcggctg ctgcacaacattctgcccaaggacgtggccgcacacttcctggcccgcgaacggcgcaac gacgagctctactatcagtcgtgcgagtgcgtggccgtcatgttcgcctccatcgccaac ttctctgagttctatgtggaactagaggccaacaacgagggcgtcgagtgcctgcggcta ctcaacgagatcatcgcagactttgacgagatcattagtgaggaccggttcaggcagctg gaaaagatcaagaccatcggcagcacctacatggccgcctccggcctcaatgactccacc tacgacaaggtgggcaagacccacatcaaagccctggccgacttcgccatgaagttgatg gaccaaatgaagtacatcaacgagcactctttcaacaacttccagatgaagatcgggctc aatattggccccgtggtggcgggtgtgattggagcccgcaagcctcagtacgacatctgg ggcaatacggtgaacgtggccagccgcatggacagcaccggtgtgcccgaccgcatccag gtcaccacagacatgtaccaggtgctggccgccaatacgtaccagctggagtgccggggt gtggtcaaggtcaagggcaaaggcgagatgatgacctacttcctcaacggaggacccccg cccagttag

Bos mutus (wild yak): 102282732 Help Entry 102282732         CDS       T02919                                  Gene name ADCY3 Definition (RefSeq) adenylate cyclase 3   KO K08043   adenylate cyclase 3 [EC:4.6.1.1] Organism bom  Bos mutus (wild yak) Pathway bom00230   Purine metabolism bom01100   Metabolic pathways bom01522   Endocrine resistance bom04015   Rap1 signaling pathway bom04020   Calcium signaling pathway bom04022   cGMP-PKG signaling pathway bom04024   cAMP signaling pathway bom04062   Chemokine signaling pathway bom04072   Phospholipase D signaling pathway bom04114   Oocyte meiosis bom04211   Longevity regulating pathway bom04213   Longevity regulating pathway - multiple species bom04261   Adrenergic signaling in cardiomyocytes bom04270   Vascular smooth muscle contraction bom04371   Apelin signaling pathway bom04540   Gap junction bom04611   Platelet activation bom04713   Circadian entrainment bom04714   Thermogenesis bom04723   Retrograde endocannabinoid signaling bom04724   Glutamatergic synapse bom04725   Cholinergic synapse bom04727   GABAergic synapse bom04740   Olfactory transduction bom04750   Inflammatory mediator regulation of TRP channels bom04911   Insulin secretion bom04912   GnRH signaling pathway bom04913   Ovarian steroidogenesis bom04914   Progesterone-mediated oocyte maturation bom04915   Estrogen signaling pathway bom04916   Melanogenesis bom04918   Thyroid hormone synthesis bom04921   Oxytocin signaling pathway bom04923   Regulation of lipolysis in adipocytes bom04925   Aldosterone synthesis and secretion bom04926   Relaxin signaling pathway bom04927   Cortisol synthesis and secretion bom04928   Parathyroid hormone synthesis, secretion and action bom04934   Cushing syndrome bom04935   Growth hormone synthesis, secretion and action bom04962   Vasopressin-regulated water reabsorption bom04970   Salivary secretion bom04971   Gastric acid secretion bom04972   Pancreatic secretion bom04976   Bile secretion bom05032   Morphine addiction bom05163   Human cytomegalovirus infection bom05166   Human T-cell leukemia virus 1 infection bom05200   Pathways in cancer bom05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:bom00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     102282732 (ADCY3)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     102282732 (ADCY3)    04371 Apelin signaling pathway     102282732 (ADCY3)    04020 Calcium signaling pathway     102282732 (ADCY3)    04072 Phospholipase D signaling pathway     102282732 (ADCY3)    04024 cAMP signaling pathway     102282732 (ADCY3)    04022 cGMP-PKG signaling pathway     102282732 (ADCY3)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     102282732 (ADCY3)   09144 Cellular community - eukaryotes    04540 Gap junction     102282732 (ADCY3)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     102282732 (ADCY3)    04062 Chemokine signaling pathway     102282732 (ADCY3)   09152 Endocrine system    04911 Insulin secretion     102282732 (ADCY3)    04923 Regulation of lipolysis in adipocytes     102282732 (ADCY3)    04912 GnRH signaling pathway     102282732 (ADCY3)    04913 Ovarian steroidogenesis     102282732 (ADCY3)    04915 Estrogen signaling pathway     102282732 (ADCY3)    04914 Progesterone-mediated oocyte maturation     102282732 (ADCY3)    04921 Oxytocin signaling pathway     102282732 (ADCY3)    04926 Relaxin signaling pathway     102282732 (ADCY3)    04935 Growth hormone synthesis, secretion and action     102282732 (ADCY3)    04918 Thyroid hormone synthesis     102282732 (ADCY3)    04928 Parathyroid hormone synthesis, secretion and action     102282732 (ADCY3)    04916 Melanogenesis     102282732 (ADCY3)    04925 Aldosterone synthesis and secretion     102282732 (ADCY3)    04927 Cortisol synthesis and secretion     102282732 (ADCY3)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     102282732 (ADCY3)    04270 Vascular smooth muscle contraction     102282732 (ADCY3)   09154 Digestive system    04970 Salivary secretion     102282732 (ADCY3)    04971 Gastric acid secretion     102282732 (ADCY3)    04972 Pancreatic secretion     102282732 (ADCY3)    04976 Bile secretion     102282732 (ADCY3)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     102282732 (ADCY3)   09156 Nervous system    04724 Glutamatergic synapse     102282732 (ADCY3)    04727 GABAergic synapse     102282732 (ADCY3)    04725 Cholinergic synapse     102282732 (ADCY3)    04723 Retrograde endocannabinoid signaling     102282732 (ADCY3)   09157 Sensory system    04740 Olfactory transduction     102282732 (ADCY3)    04750 Inflammatory mediator regulation of TRP channels     102282732 (ADCY3)   09149 Aging    04211 Longevity regulating pathway     102282732 (ADCY3)    04213 Longevity regulating pathway - multiple species     102282732 (ADCY3)   09159 Environmental adaptation    04713 Circadian entrainment     102282732 (ADCY3)    04714 Thermogenesis     102282732 (ADCY3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102282732 (ADCY3)   09165 Substance dependence    05032 Morphine addiction     102282732 (ADCY3)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     102282732 (ADCY3)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     102282732 (ADCY3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102282732 (ADCY3)    05163 Human cytomegalovirus infection     102282732 (ADCY3)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     102282732 (ADCY3) Enzymes [BR:bom01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      102282732 (ADCY3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N HNOBA Peptidase_S49_N Motif Other DBs NCBI-GeneID:  102282732 NCBI-ProteinID:  XP_005895740 LinkDB All DBs Position Un AA seq 1145 aa AA seqDB search MPRTQGFSEPEYSAEYSAEYSVSLPSDPDRGVGRTHEISVRNSGSCLCLPRFMRLTFVPE SLENLYQTYFKRQRHETLLVLVVFAALFDCYVVVMCAVVFSGDKLAPLAVAGVGLVLDII LFVLCKKGLLPNRVTRRVVPYLLWLLISAQVFSYLGLNFSRAHAASDTVGWQAFFVFSFF ITLPLSLSPIVIISVVSCVVHTLVLGVTVAQQQQDGLKGVQLLREILANVFLYLCAIVVG IMSYYMADRKHRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKDMKKDES QKDQQQFNTMYMYRHENVSILFADIVGFTQLSSACSAQELVKLLNELFARFDKLAAKYHQ LRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAISYVREKTKTGVDMRVGVHTGTV LGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTMDCLKGEFDVEPGEGGSRCD YLEEKGIETYLIIASKPEVKKTAAQNGLNGSVTPNGAPPSSKPSSPALIETKESNGSIHT SGSISEEPEEQDAQADNPSFPNPRRRLRLQDLADRVVDASEDEHELNQLLNEALLERESA QVVKKRNTFLLSMRFMDPEMETRYSVEKEKQSGAAFSCSCVVLLCTAVVEILIDPWLMTN YVTFVVGEALLLILTICSLAAIFPRAFPKKLVAFSTWIDRTRWARNTWAMLAIFILVMAN VVDMLSCLQYYTGPTNGTAEMQVEDGCVENPKYYNYVAVLSLIATIMLVQVSHMVKLTLM LLIAGAVAVINIYAWCPIFDDYDRKRFQQHDFPMVALEKMQVFSSSGLNGTDRLPLVPSK YSMTVMIFVMMLSFYYFSRHVEKLARTLFLWKIEVHDQKERVYEMRRWNEALVTNMLPEH VARHFLGSKKRDEELYSQSYDEIGVMFASLPNFADFYTEESINNGGIECLRFLNEIISDF DSLLDNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFTSSNKDEKSDKERWQHLADLADF ALAMKDTLTNINNQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGV MGNIQVVEETQVILREYGFRFVRRGPIFVKGKGELLTFFLKGRDKLATFPNGASITLPHQ VVDNS NT seq 3438 nt NT seq  +upstreamnt  +downstreamnt atgccgaggacccagggcttctccgagcccgagtactccgcggagtactcggccgagtac tctgtcagcctgccttcggaccctgaccgcggggtgggccggacccatgaaatctctgtc cggaactcggggtcgtgcctctgcttgcctcgcttcatgcggctgaccttcgtaccagag tccttggagaacctgtaccagacctacttcaagaggcagcgccacgagaccctgctggtg ctggtggtcttcgcggccctcttcgactgctatgtggtggtcatgtgcgctgtggtcttc tctggcgacaagctggcccccctggccgtggctggggtcgggctggtgttggacatcatc cttttcgtgctctgcaaaaaggggctgctccccaaccgggtcactcggagagtggtgccc tacctgctgtggctgctgatatcagcccaggtcttctcctacctgggcctgaacttctcc cgtgcccacgcggccagcgacacggtgggctggcaggccttcttcgtcttctccttcttc atcacgctgccgctcagcctcagccccattgtcatcatctccgtggtctcctgcgtcgtg cacacactcgtcttaggggtcactgtggcccagcagcagcaggatgggctgaagggagtg cagttgctgagggagattctggccaacgtcttcctctacctgtgcgccatcgtcgtgggc atcatgtcctactacatggcagaccgcaagcaccgcaaggccttcctggaggcccgccag tctctggaggtgaagatgaacctggaggagcagagtcagcagcaggagaaccttatgctc tccatcctgcccaagcacgtggccgacgagatgctgaaggacatgaagaaggatgagagc cagaaggaccagcagcagttcaacaccatgtacatgtaccgccatgagaacgtcagcatc ctctttgctgatatcgtgggcttcacccagctgtcctcagcctgcagcgcccaggagctt gtgaagctgctcaatgagctctttgcccgcttcgacaagctggcggctaaataccaccag ctgcggattaagatcctgggcgactgttactactgcatctgtgggctgcctgactaccgg gaggaccacgccgtctgctccatcctcatggggctcgccatggtggaggccatctcgtac gtgcgggagaagacgaagaccggggtggacatgcgcgtgggggtgcacacgggcaccgtg ctggggggcgtcctcggccagaaacgctggcagtacgacgtgtggtccaccgacgttacc gtggccaacaagatggaggctggcggcatccctgggcgcgtgcacatctcccagagcacc atggactgcctgaaaggagagttcgacgtggagccgggcgaggggggcagtcgctgtgat tacctggaagagaagggcatcgagacctacctcatcatcgcgtccaagccagaggtgaag aagacagctgcccaaaacggcctcaacggctcggtgaccccaaacggggcgccgccttcc tcaaagcccagctcccctgccctcattgagaccaaggagtccaacgggagcattcacacc agcggctctatatctgaggagcccgaggagcaagatgcccaggccgacaacccctcgttc cccaaccctcgccggaggctgcgccttcaggacctggctgatcgcgtggtggacgcctcc gaggacgagcatgagctcaaccagctactcaacgaggcgctgctagagcgggagtctgcc caggtagtgaagaagagaaacaccttcctcctgtccatgcggttcatggaccccgagatg gaaacccgctactcggtggagaaggagaagcagagcggggctgccttcagctgctcctgc gttgtcctgctctgcacggccgtggtggagatcctcattgacccctggctcatgacgaac tatgtgacctttgtggttggggaggctctgctcctgatcctgacaatctgctcgctggct gccatctttccgcgggcctttcctaagaagctcgtggccttctctacttggattgaccgg acgcgctgggccaggaacacctgggccatgctggccatcttcattcttgtcatggcaaac gtggtggacatgctcagctgtctccagtactacacaggacccaccaacggcaccgcagag atgcaggtggaggatggctgtgtggagaaccccaagtattacaactacgtggccgtgctg tccctcatcgccaccatcatgctggtgcaggtcagccacatggtcaagctcacactcatg ctgctcatcgcgggggccgtggctgtcatcaacatctacgcctggtgccccatctttgac gactacgaccgcaaacgcttccagcaacacgactttccgatggtggccttagagaagatg caggtgttttccagctcggggctcaatggcactgacaggctgcccctggtgccgtctaag tactcgatgacagtgatgatcttcgtcatgatgctgagcttttactacttctcccgccac gtggaaaagctggcacggacactgttcttgtggaagattgaggtccacgaccagaaggaa cgtgtctatgagatgcgacgctggaatgaagccttggtcaccaacatgctgcctgaacac gtggcacgccatttcctggggtccaagaagagagatgaggagctgtacagccagtcttat gatgagattggagttatgtttgcctccctgcccaattttgctgacttctacacagaggag agcatcaataacggtggcattgagtgtctacgcttcctcaatgagatcatctcagatttt gactctcttctggacaatcccaagttccgggtcatcaccaagatcaagaccattggtagc acctacatggcagcttcaggagtcaccccagatgtcaacaccaatggctttaccagctcc aacaaggacgagaagtcagacaaggagcgctggcagcacctggcagatctggccgatttt gcgctggccatgaaggacacgctcaccaacatcaacaaccagtccttcaacaacttcatg ctgcgcattggaatgaacaaaggaggggtcctggctggggtcattggagcccggaaacca cactatgacatctggggcaacacagtcaacgtagccagcaggatggagtccacaggggtc atgggcaacatccaggtggtggaagaaacccaagtcatccttcgagaatacggcttccgc ttcgtgaggagagggcccatctttgtgaaagggaagggggaactgctaacctttttcttg aagggccgagacaagctggccacattccctaacggcgcctcaatcacactgcctcaccag gtggtagacaactcctga

Bos mutus (wild yak): 102285642 Help Entry 102285642         CDS       T02919                                  Gene name ADCY9 Definition (RefSeq) adenylate cyclase 9   KO K08049   adenylate cyclase 9 [EC:4.6.1.1] Organism bom  Bos mutus (wild yak) Pathway bom00230   Purine metabolism bom01100   Metabolic pathways bom01522   Endocrine resistance bom04015   Rap1 signaling pathway bom04020   Calcium signaling pathway bom04022   cGMP-PKG signaling pathway bom04024   cAMP signaling pathway bom04062   Chemokine signaling pathway bom04072   Phospholipase D signaling pathway bom04114   Oocyte meiosis bom04211   Longevity regulating pathway bom04213   Longevity regulating pathway - multiple species bom04261   Adrenergic signaling in cardiomyocytes bom04270   Vascular smooth muscle contraction bom04371   Apelin signaling pathway bom04540   Gap junction bom04611   Platelet activation bom04713   Circadian entrainment bom04714   Thermogenesis bom04723   Retrograde endocannabinoid signaling bom04724   Glutamatergic synapse bom04725   Cholinergic synapse bom04727   GABAergic synapse bom04750   Inflammatory mediator regulation of TRP channels bom04911   Insulin secretion bom04912   GnRH signaling pathway bom04913   Ovarian steroidogenesis bom04914   Progesterone-mediated oocyte maturation bom04915   Estrogen signaling pathway bom04916   Melanogenesis bom04918   Thyroid hormone synthesis bom04921   Oxytocin signaling pathway bom04923   Regulation of lipolysis in adipocytes bom04925   Aldosterone synthesis and secretion bom04926   Relaxin signaling pathway bom04927   Cortisol synthesis and secretion bom04928   Parathyroid hormone synthesis, secretion and action bom04934   Cushing syndrome bom04935   Growth hormone synthesis, secretion and action bom04961   Endocrine and other factor-regulated calcium reabsorption bom04962   Vasopressin-regulated water reabsorption bom04970   Salivary secretion bom04971   Gastric acid secretion bom04972   Pancreatic secretion bom04976   Bile secretion bom05032   Morphine addiction bom05163   Human cytomegalovirus infection bom05166   Human T-cell leukemia virus 1 infection bom05200   Pathways in cancer bom05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:bom00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     102285642 (ADCY9)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     102285642 (ADCY9)    04371 Apelin signaling pathway     102285642 (ADCY9)    04020 Calcium signaling pathway     102285642 (ADCY9)    04072 Phospholipase D signaling pathway     102285642 (ADCY9)    04024 cAMP signaling pathway     102285642 (ADCY9)    04022 cGMP-PKG signaling pathway     102285642 (ADCY9)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     102285642 (ADCY9)   09144 Cellular community - eukaryotes    04540 Gap junction     102285642 (ADCY9)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     102285642 (ADCY9)    04062 Chemokine signaling pathway     102285642 (ADCY9)   09152 Endocrine system    04911 Insulin secretion     102285642 (ADCY9)    04923 Regulation of lipolysis in adipocytes     102285642 (ADCY9)    04912 GnRH signaling pathway     102285642 (ADCY9)    04913 Ovarian steroidogenesis     102285642 (ADCY9)    04915 Estrogen signaling pathway     102285642 (ADCY9)    04914 Progesterone-mediated oocyte maturation     102285642 (ADCY9)    04921 Oxytocin signaling pathway     102285642 (ADCY9)    04926 Relaxin signaling pathway     102285642 (ADCY9)    04935 Growth hormone synthesis, secretion and action     102285642 (ADCY9)    04918 Thyroid hormone synthesis     102285642 (ADCY9)    04928 Parathyroid hormone synthesis, secretion and action     102285642 (ADCY9)    04916 Melanogenesis     102285642 (ADCY9)    04925 Aldosterone synthesis and secretion     102285642 (ADCY9)    04927 Cortisol synthesis and secretion     102285642 (ADCY9)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     102285642 (ADCY9)    04270 Vascular smooth muscle contraction     102285642 (ADCY9)   09154 Digestive system    04970 Salivary secretion     102285642 (ADCY9)    04971 Gastric acid secretion     102285642 (ADCY9)    04972 Pancreatic secretion     102285642 (ADCY9)    04976 Bile secretion     102285642 (ADCY9)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     102285642 (ADCY9)    04961 Endocrine and other factor-regulated calcium reabsorption     102285642 (ADCY9)   09156 Nervous system    04724 Glutamatergic synapse     102285642 (ADCY9)    04727 GABAergic synapse     102285642 (ADCY9)    04725 Cholinergic synapse     102285642 (ADCY9)    04723 Retrograde endocannabinoid signaling     102285642 (ADCY9)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     102285642 (ADCY9)   09149 Aging    04211 Longevity regulating pathway     102285642 (ADCY9)    04213 Longevity regulating pathway - multiple species     102285642 (ADCY9)   09159 Environmental adaptation    04713 Circadian entrainment     102285642 (ADCY9)    04714 Thermogenesis     102285642 (ADCY9)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102285642 (ADCY9)   09165 Substance dependence    05032 Morphine addiction     102285642 (ADCY9)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     102285642 (ADCY9)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     102285642 (ADCY9)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102285642 (ADCY9)    05163 Human cytomegalovirus infection     102285642 (ADCY9)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     102285642 (ADCY9) Enzymes [BR:bom01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      102285642 (ADCY9) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc DUF512 DUF1053 Motif Other DBs NCBI-GeneID:  102285642 NCBI-ProteinID:  XP_005901380 UniProt:  L8IB07 LinkDB All DBs Position Un AA seq 1354 aa AA seqDB search MASPPHQQLLQHHSTEVSCDSSGDSNSVRVRINPKQPSSNSHPKHCKYSISSSCSSSGDS GGVPRRMGAGGRLRRRKKLPQLFERASSRWWDPKFDSVNLEEACMERCFPQTQRRFRYAL FYIGFACLLWSIYFGVHMKSKLIVMVAPALCFLVVCVGFFLFTFTKLYARHYVWTSLVLT LLVFALTLAAQFQVLTPLSGRVDNFNHTRAARPTDTCLSQVGSFSMCIEVLFLLYTVMHL PLYLSLILGVAYSVLFETFGYHFQDEACFASPGAEALHWELLSRALLHLCIHAIGIHLFI MSQVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRIIADDLMKQGDEESENSVKR HATSSPKNRKKKSSIQKAPIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAHALVGLLN DLFGRFDRLCEETKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIRAIEQFCQEK KEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEATAKYLD DRYEMEDGKVTERLGQSVVADQLKGLKTYLIAGQRAKESHCSCSEALLSGFEVLDGSRVS SGPRGQGTASPGSVSDLAQTVKTFDNLKTCPSCGITFTPKPEAGAEGGAVQNGCQEEPKN SAKASGGPSSKTQNGLLSPPPEEKLTNSQTSLCEILQEKGRWAGVSLDQSALLPLRFKNI REKTDAHFVDVIKEDSLMKDYFFKPPINQFSLNFLDPELERAYRTSYQEEVVKSSPVRTF ASATFSSLLDVLLSTTVFLILSITCFLRYGAASTPPPPAALAVFGAALLLEILSLVVSVR MVFFLEDVMTCTKRLLEWIAGWLPRHFIGAILVSLPALAVYSHVTSEFETNIHSTMFTGS AVLTAVVQYCNFCQLSSWMRSSLATVVGAGPLLLLLYISLCPDSSTVISHLDAVQNFSST RKLCNASLSHDGRSPASLIGQEVILVFFLLLLLVWFLNREFEVSYRLHYHGDVEADLHRT KIQSMRDQADWLLRNIIPYHVAEQLKVSQTYSKNHDSGGVIFASIVNFSEFYEENYEGGK ECYRVLNELIGDFDELLSKPDYSSIEKIKTIGATYMAASGLNATQCRDGSHPQEHLQILF EFAKEMMRVVDDFNNNMLWFNFKLRVGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDT TGVECRIQVSEESYRVLSKMGYEFDYRGTVNVKGKGQMKTYLYPKCTDSGLVPQHQLSIS PDIRVQVDGSIGRSPTDEIASLVPSVQNPDQVSPGSENNAQTRDAHPSAKRPWKEPVRAE ERCRFGKAIEKSDCEEVGMEEANELTKLNVSERA NT seq 4065 nt NT seq  +upstreamnt  +downstreamnt atggcttccccgccccaccagcagctgctgcagcaccacagcaccgaggtgagctgtgac tccagcggagacagcaacagcgtgcgggtcaggatcaaccccaagcagccgtcctccaac agccacccgaagcactgcaagtacagcatctcctccagctgcagcagctccggggactcc ggaggggtcccccgaagaatgggcgcgggaggccgcctgcgcaggaggaagaagctgccc cagctgttcgaacgggcctccagccggtggtgggaccccaagtttgactctgtgaacctg gaggaggcttgcatggagcgttgcttcccgcagacccagcgccgcttccggtatgcgctc ttctacatcggcttcgcctgccttctctggagcatctattttggggtccacatgaaatcg aaactgattgtcatggtagcccctgctctgtgcttcctcgtggtgtgtgtgggctttttt ctgtttaccttcaccaagttgtacgcccgccattacgtgtggacttcgctggttctcacc ctcctggtattcgccctgaccctggctgcccagtttcaggttttgacgcccctctcagga cgagttgacaacttcaatcatactcgggctgccaggcccacagacacttgcttatctcaa gtggggagcttttccatgtgcatcgaagtgctctttttgctctacaccgtcatgcactta cctttgtacttgagcttgattttgggagtggcctattctgttctttttgagacctttggc taccacttccaagatgaagcctgctttgcctcacctggagcggaggctctgcactgggag ctgctgagccgggccctgctccacctctgcatccacgccatcgggatccacctgttcatc atgtcccaggtgagatccaggagcaccttcctcaaggtgggccagtctattatgcacgga aaggatctggaagtggaaaaggccctgaaagagaggatgattcattctgtgatgccaaga atcatagctgatgacttgatgaaacagggggatgaggagagtgagaattctgtcaaaagg cacgccacctccagccccaagaacaggaagaagaagtcttccatccagaaagcccctatc gccttccgcccgtttaagatgcagcagatcgaagaagtcagtattttatttgcagatatt gtgggcttcaccaagatgagtgccaataagtctgcccacgccctggtgggtctcctcaac gatctgttcggccgctttgaccggttgtgtgaggagaccaaatgtgagaaaatcagcacc ttgggagactgctactattgtgtggctgggtgtcctgagccaagggccgaccatgcctac tgctgcatcgagatggggttgggcatgataagagccattgaacagttctgccaagagaag aaagagatggtgaacatgcgcgttggggttcacacagggaccgtcctgtgtggcatcttg ggcatgaggaggtttaaatttgatgtgtggtccaatgatgtgaacttggccaatctcatg gagcagctgggagtggctggcaaggttcacatttccgaggccaccgcaaaatacctagat gaccggtacgaaatggaggatgggaaagttactgaacgccttggccagagtgttgttgct gaccagttgaaaggtttgaagacatacctgatagcgggtcagagagcgaaggagtctcac tgcagctgttcagaggccttactttctggctttgaggtccttgacggctcgcgggtgtcc tcaggccctaggggacaggggacagcgtcgccagggagtgtcagtgacttggcgcagact gtcaaaacctttgataaccttaagacctgcccatcgtgcggaatcacgttcactcccaag ccagaagctggtgcagaaggtggagcggtccagaacggctgtcaggaggagcccaagaac agcgccaaggcctccggaggacccagctccaaaacgcaaaatggacttctgagtcctccc ccggaggagaagctcaccaacagtcagacctccctgtgcgagatcttacaggagaagggc aggtgggcaggcgtgagcctggatcagtcggctctccttccgctgaggttcaagaacatc cgggagaaaacggatgcccactttgtcgacgttatcaaggaagacagcctgatgaaagac tacttttttaagccgcccattaaccagttcagcttgaacttcctggatccggagctcgag cgggcctacaggaccagctatcaagaagaggttgtaaagagctctcccgtgaggactttc gccagtgccaccttcagctccctcctggatgtgcttctgtcgacaacagtgtttctgatt ctctccatcacctgcttcctgaggtacggggccgcctccacgccgcccccgccggccgcc ctggcagtcttcggagcggccctgctgctggagatcctgtccctcgtggtctctgtcagg atggtgttcttcctggaggacgtgatgacgtgcacgaagcgcctgctggagtggatagcc ggctggctcccgcgccatttcatcggggccatcctggtgtctctccccgccctggcagtg tattcacacgtcacctctgaatttgaaacaaacatacactccaccatgttcacgggctcg gccgtgctgaccgccgtggtgcaatactgcaacttctgccagctcagctcctggatgcgg tcctccctggccactgtcgtcggggccgggcccctgctgctgctgctctacatctccctg tgcccggacagttccactgtaatttcacaccttgatgcagtacagaatttcagctccacc aggaagctgtgcaacgcctcgctgtctcacgacggcaggagcccagccagcctgatcggc caggaggtgattctcgtcttcttcctcctgctcctgttggtctggttcctgaaccgagag ttcgaagtcagctaccgcctgcactaccacggggacgtggaggcggacctgcaccgcacc aagatccagagcatgagggaccaggccgactggctgctgcggaacatcatcccctaccac gtggccgagcagctcaaggtgtcccagacctactccaagaaccacgacagcggaggcgtc atcttcgccagcatcgtcaacttcagcgagttctacgaggagaactacgagggcggcaag gagtgctacagggtcctcaacgagctgatcggggactttgacgagctcctgagcaagccg gactacagcagcatcgagaagatcaagaccatcggggccacgtacatggccgcgtccggg ctgaacgccacgcagtgccgcgacggcagccacccgcaggagcacctgcagatcctcttc gagttcgccaaggagatgatgcgtgtggtggacgacttcaacaacaacatgctgtggttc aacttcaagctcagggtgggcttcaaccacgggcccctgacggcgggcgtcatcggcacc accaagctgctgtacgacatctggggggacacggtcaacatcgccagcaggatggacacc acgggggtggagtgccgcatccaggtcagcgaggagagctaccgcgtcctgagcaagatg ggctacgagttcgactaccgagggacggtgaatgtcaagggcaaaggccaaatgaagacc tacctgtaccccaagtgcacagacagtgggttggtgccacagcaccagctgtccatctca cccgacatccgggtccaggtggatggcagcatcggacgctcccccacagacgagatagcc agcctggtgccttccgttcagaacccggaccaggtgtccccgggttccgagaacaacgcc cagaccagggacgctcacccgtctgctaagagaccctggaaggagccagtcagagccgag gaaaggtgtcggttcggcaaagccatagagaaaagcgactgtgaagaagtggggatggag gaagccaacgaactcacgaagctcaacgtctcagagagggcgtga

Bos mutus (wild yak): 102286168 Help Entry 102286168         CDS       T02919                                  Gene name ADCY4 Definition (RefSeq) adenylate cyclase 4   KO K08044   adenylate cyclase 4 [EC:4.6.1.1] Organism bom  Bos mutus (wild yak) Pathway bom00230   Purine metabolism bom01100   Metabolic pathways bom01522   Endocrine resistance bom04015   Rap1 signaling pathway bom04020   Calcium signaling pathway bom04022   cGMP-PKG signaling pathway bom04024   cAMP signaling pathway bom04062   Chemokine signaling pathway bom04072   Phospholipase D signaling pathway bom04114   Oocyte meiosis bom04211   Longevity regulating pathway bom04213   Longevity regulating pathway - multiple species bom04261   Adrenergic signaling in cardiomyocytes bom04270   Vascular smooth muscle contraction bom04371   Apelin signaling pathway bom04540   Gap junction bom04611   Platelet activation bom04713   Circadian entrainment bom04714   Thermogenesis bom04723   Retrograde endocannabinoid signaling bom04724   Glutamatergic synapse bom04725   Cholinergic synapse bom04727   GABAergic synapse bom04742   Taste transduction bom04750   Inflammatory mediator regulation of TRP channels bom04911   Insulin secretion bom04912   GnRH signaling pathway bom04913   Ovarian steroidogenesis bom04914   Progesterone-mediated oocyte maturation bom04915   Estrogen signaling pathway bom04916   Melanogenesis bom04918   Thyroid hormone synthesis bom04921   Oxytocin signaling pathway bom04923   Regulation of lipolysis in adipocytes bom04925   Aldosterone synthesis and secretion bom04926   Relaxin signaling pathway bom04927   Cortisol synthesis and secretion bom04928   Parathyroid hormone synthesis, secretion and action bom04934   Cushing syndrome bom04935   Growth hormone synthesis, secretion and action bom04970   Salivary secretion bom04971   Gastric acid secretion bom04972   Pancreatic secretion bom04976   Bile secretion bom05032   Morphine addiction bom05163   Human cytomegalovirus infection bom05166   Human T-cell leukemia virus 1 infection bom05200   Pathways in cancer bom05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:bom00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     102286168 (ADCY4)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     102286168 (ADCY4)    04371 Apelin signaling pathway     102286168 (ADCY4)    04020 Calcium signaling pathway     102286168 (ADCY4)    04072 Phospholipase D signaling pathway     102286168 (ADCY4)    04024 cAMP signaling pathway     102286168 (ADCY4)    04022 cGMP-PKG signaling pathway     102286168 (ADCY4)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     102286168 (ADCY4)   09144 Cellular community - eukaryotes    04540 Gap junction     102286168 (ADCY4)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     102286168 (ADCY4)    04062 Chemokine signaling pathway     102286168 (ADCY4)   09152 Endocrine system    04911 Insulin secretion     102286168 (ADCY4)    04923 Regulation of lipolysis in adipocytes     102286168 (ADCY4)    04912 GnRH signaling pathway     102286168 (ADCY4)    04913 Ovarian steroidogenesis     102286168 (ADCY4)    04915 Estrogen signaling pathway     102286168 (ADCY4)    04914 Progesterone-mediated oocyte maturation     102286168 (ADCY4)    04921 Oxytocin signaling pathway     102286168 (ADCY4)    04926 Relaxin signaling pathway     102286168 (ADCY4)    04935 Growth hormone synthesis, secretion and action     102286168 (ADCY4)    04918 Thyroid hormone synthesis     102286168 (ADCY4)    04928 Parathyroid hormone synthesis, secretion and action     102286168 (ADCY4)    04916 Melanogenesis     102286168 (ADCY4)    04925 Aldosterone synthesis and secretion     102286168 (ADCY4)    04927 Cortisol synthesis and secretion     102286168 (ADCY4)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     102286168 (ADCY4)    04270 Vascular smooth muscle contraction     102286168 (ADCY4)   09154 Digestive system    04970 Salivary secretion     102286168 (ADCY4)    04971 Gastric acid secretion     102286168 (ADCY4)    04972 Pancreatic secretion     102286168 (ADCY4)    04976 Bile secretion     102286168 (ADCY4)   09156 Nervous system    04724 Glutamatergic synapse     102286168 (ADCY4)    04727 GABAergic synapse     102286168 (ADCY4)    04725 Cholinergic synapse     102286168 (ADCY4)    04723 Retrograde endocannabinoid signaling     102286168 (ADCY4)   09157 Sensory system    04742 Taste transduction     102286168 (ADCY4)    04750 Inflammatory mediator regulation of TRP channels     102286168 (ADCY4)   09149 Aging    04211 Longevity regulating pathway     102286168 (ADCY4)    04213 Longevity regulating pathway - multiple species     102286168 (ADCY4)   09159 Environmental adaptation    04713 Circadian entrainment     102286168 (ADCY4)    04714 Thermogenesis     102286168 (ADCY4)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102286168 (ADCY4)   09165 Substance dependence    05032 Morphine addiction     102286168 (ADCY4)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     102286168 (ADCY4)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     102286168 (ADCY4)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102286168 (ADCY4)    05163 Human cytomegalovirus infection     102286168 (ADCY4)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     102286168 (ADCY4) Enzymes [BR:bom01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      102286168 (ADCY4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc DUF1053 AC_N CD52 Motif Other DBs NCBI-GeneID:  102286168 NCBI-ProteinID:  XP_005910346 UniProt:  L8HRR9 LinkDB All DBs Position Un AA seq 1077 aa AA seqDB search MARLFSPRQPPSEDLFYETYYSLSQQYPLLLLLLLIVLLGLLALLPVAWASGRELAADPA FLTTVLCALGGFSLLLVLASREQRLQRWTRPLSGLVWAALLALGHSFLFTGGVVSAWDQV SFFLFVIFTVYAMLPLDMRDAITAGVTSSLSHLLVLGLYLGPQPDSRPALLPQLAANAVL FLCGNAAGAYHKALMERALRATFREALSSLHSRRRLDTEKKHQEHLLLSILPAYLAREMK EEIMARLQAGQGSRPESTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKELVLMLNE LFGKFDQIAKEHECMRIKILGDCYYCVSGLPLSLPDHAINCVRMGLDMCRAIRKLRAATG VDINMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEASGVPGRVHITGATLALLAG AYAVEDAAMEHRDPYLRELGEPTYLVIDPWAAEEDEKGTAGGLLSSLEGSKMRPSLLMTR YLESWGAAKPFAHLSHVESPVSTSTPLPEKALSSFSPQWSLDRSRTMRGPDEELDTGDAK FFQVIEQLNSQKQWKQSKDFNPLTLYFREKEMEKEYRLSALPAFKYYAACTFLVFLSNFI IQMLVTNRPPALTITYGITFLLFFLLLFVCFSEYLMKCVLKGPKMLHWLPTLSVLVATRP GLRVALGTATILLVFVMAITSLVFLPATSACPFQAPNMSSMASNLSWELPGSLPLISIPY SMHCCVLGFLSCSLFLHMSFELKLLLLLLWLTASCSIFLHSHAWLSDCLIARLYLGTLDS RPGVLKEPKLMGAVSFFIFFFTLLVLARQNEYYCRLDFLWKKKLRQEQEETETMENLTRL LLENVLPAHVAPQFIGQNRRNEDLYHQSYECVCVLFASVPDFKEFYSESSINHEGLECLR LLNEIIADFDELLSKPKFSGVEKIKTICSTYMAATGLNATSGQDAQQDAEQSCGHLGTMV EFAVALGSKLDVINKHSFNNFRLRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRMEST GVLGKIQVTEETAWALQSLGYTCYSRGIIKVKGKGQLCTYFLNTDLTRTGPPSATLG NT seq 3234 nt NT seq  +upstreamnt  +downstreamnt atggcccgcctcttcagtccacggcagccccccagcgaagacctcttctacgagacctac tacagcctgagccagcagtacccactgctgctgctgctgctgctgatcgtgctcttgggg ctcctggcgctgctccctgtggcctgggcaagtggcagggagctggccgcagacccagcc ttcctgaccactgtgctgtgcgctctgggtggcttctcactgctgctggtcctggcttcc cgggagcagcgactgcagcgctggacgcgtcccctgtcaggcctcgtgtgggcagcactg cttgcactaggccacagcttcctgttcactgggggcgtggtgagcgcctgggaccaggtg tcctttttcctctttgtcatcttcactgtgtatgccatgttgcccctggacatgcgggac gccatcaccgcgggtgtcacctcctcactctcacacttgctggtccttgggctgtatctt gggcctcagcccgactctcggccggcgctgctgccacagctggctgcaaacgcggtgctg ttcctgtgcgggaacgcggccggagcctatcacaaggcgctgatggagcgcgcgctgcgc gccacgttccgggaggcgcttagttccctgcactcgcggcggagactggacaccgagaag aagcatcaggaacaccttctcttgtccatccttcctgcctacctggcccgagagatgaag gaggagatcatggcacggctgcaggctggacaggggtcacggccagagagcaccaacaac ttccacagcctctatgtcaagaggcaccagggagtcagcgtgctgtatgctgacatcgtg ggcttcacgagactggccagtgagtgctcccctaaggagttggtgcttatgctcaacgag ctctttggcaagttcgaccaaatcgccaaggagcacgaatgcatgcggatcaagatccta ggagactgttactactgtgtctccggcctgccgctctcactgcctgaccacgccatcaac tgtgtgcgcatggggctggacatgtgccgggccatcaggaaacttcgggcagccacaggc gtggatatcaacatgcgtgtgggcgtgcactcaggcagcgtgctctgcggggtcatcggg ctacagaaatggcagtatgatgtctggtcccatgacgtcactctggccaaccacatggag gcgagtggagtgccaggacgagtacatatcacaggggctacgctggccctgctggccggg gcttatgctgtggaggatgcagccatggaacaccgggacccataccttcgggagctaggg gagccgacctacctggtcatcgacccctgggctgcagaggaggacgagaagggtactgca ggagggttgctgtcctctcttgagggctccaagatgcgtccatcactgctgatgacccgc tacctggagtcctggggtgcagccaagcctttcgcccacctgagccacgtggagagccct gtgtccacatctacccctctcccggagaaggccctgtcttccttcagcccccagtggagc ctggaccggagccgtaccatgaggggacctgatgaggaactagacactggggatgccaag ttcttccaggtcatcgaacagctcaattctcagaaacaatggaaacagtcgaaggacttc aatccactgacactgtacttcagagagaaggagatggagaaagagtatcggctctctgca ctccccgccttcaaatactatgcagcctgcaccttcctggtttttctctccaacttcatt atccagatgctggtgacaaacaggcctccagctctgaccatcacctatggcatcaccttc ctcctcttcttcctcctcctcttcgtctgcttctcagagtacctgatgaagtgtgtcttg aaaggccccaagatgctgcactggctacccaccctgtctgtcctggtggccacacggcca ggactgcgagtggctctgggcaccgctaccatcctgctcgtcttcgtcatggccattacc agtctggtcttcttaccagcaacatcagcctgcccttttcaggctcccaatatgtcttcc atggcttccaacctctcctgggagctccctgggtccctgcctctcatcagcatcccatac tccatgcactgctgcgtgttgggcttcctctcctgctccctcttcctgcacatgagcttt gagctgaagctgctgctgctcctgctgtggctgacggcctcctgctccatcttcctgcac tcccacgcctggttgtccgactgcctcatcgcccgcctctacctgggcaccttggactcc aggccaggggtgctgaaggagcccaaactgatgggagcagtctccttcttcatcttcttc ttcaccctcctagtcctggctcggcagaatgaatattactgccgcctggactttctgtgg aagaagaagctgaggcaagagcaggaggagacagagacaatggagaacctgactcggctg ctcttggagaacgtgctccctgcgcacgtggccccccagttcattggtcagaatcggcgc aatgaggacctctaccaccagtcctatgagtgtgtgtgtgtcctcttcgcctcggtccca gacttcaaggagttctactctgaatccagcatcaaccatgaggggctagagtgtctgcgg ctgctcaatgagataatcgctgattttgatgagctgctctccaagcccaagttcagtggg gtggagaagatcaaaactatctgcagcacctacatggcagctaccggcttgaacgccacc tctggacaggatgcacagcaggatgctgagcaaagctgcggccaccttggcaccatggta gagtttgctgtggcccttgggtctaagctggatgtcatcaacaagcactcattcaacaac tttcgcttgcgtgtagggttaaaccacggacctgtagtggctggagtgattggggcccag aaaccacaatatgacatctggggcaacacggtgaatgtggccagccgcatggagagcaca ggtgtcctgggcaagattcaggtaacagaagagacagcctgggccctccagtccttaggc tacacctgctacagccggggcatcatcaaggtcaaaggcaaagggcagctctgcacctac ttcttgaacacagatttgacacgaactggacctccctcagccaccctaggctga

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