Bos mutus (wild yak): 102267975
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Entry
102267975 CDS
T02919
Gene name
ERBB2
Definition
(RefSeq) erb-b2 receptor tyrosine kinase 2
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
bom
Bos mutus (wild yak)
Pathway
bom01521
EGFR tyrosine kinase inhibitor resistance
bom01522
Endocrine resistance
bom01524
Platinum drug resistance
bom04010
MAPK signaling pathway
bom04012
ErbB signaling pathway
bom04020
Calcium signaling pathway
bom04066
HIF-1 signaling pathway
bom04151
PI3K-Akt signaling pathway
bom04510
Focal adhesion
bom04520
Adherens junction
bom04530
Tight junction
bom05200
Pathways in cancer
bom05205
Proteoglycans in cancer
bom05206
MicroRNAs in cancer
bom05212
Pancreatic cancer
bom05213
Endometrial cancer
bom05215
Prostate cancer
bom05219
Bladder cancer
bom05223
Non-small cell lung cancer
bom05224
Breast cancer
bom05226
Gastric cancer
bom05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
bom00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102267975 (ERBB2)
04012 ErbB signaling pathway
102267975 (ERBB2)
04066 HIF-1 signaling pathway
102267975 (ERBB2)
04020 Calcium signaling pathway
102267975 (ERBB2)
04151 PI3K-Akt signaling pathway
102267975 (ERBB2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
102267975 (ERBB2)
04520 Adherens junction
102267975 (ERBB2)
04530 Tight junction
102267975 (ERBB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102267975 (ERBB2)
05206 MicroRNAs in cancer
102267975 (ERBB2)
05205 Proteoglycans in cancer
102267975 (ERBB2)
05230 Central carbon metabolism in cancer
102267975 (ERBB2)
09162 Cancer: specific types
05212 Pancreatic cancer
102267975 (ERBB2)
05226 Gastric cancer
102267975 (ERBB2)
05219 Bladder cancer
102267975 (ERBB2)
05215 Prostate cancer
102267975 (ERBB2)
05213 Endometrial cancer
102267975 (ERBB2)
05224 Breast cancer
102267975 (ERBB2)
05223 Non-small cell lung cancer
102267975 (ERBB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
102267975 (ERBB2)
01524 Platinum drug resistance
102267975 (ERBB2)
01522 Endocrine resistance
102267975 (ERBB2)
Enzymes [BR:
bom01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
102267975 (ERBB2)
Protein kinases [BR:
bom01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
102267975 (ERBB2)
Exosome [BR:
bom04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
102267975 (ERBB2)
CD molecules [BR:
bom04090
]
Proteins
102267975 (ERBB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
APH
Kinase-like
Motif
Other DBs
NCBI-GeneID:
102267975
NCBI-ProteinID:
XP_005898067
LinkDB
All DBs
Position
Un
AA seq
1222 aa
AA seq
DB search
MKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPADASLSFLQEIQEVQGYVLIAHNQ
VSQVPLQRLRIVRGTQLFEEHYALAVLDNGDFLESAAPAAGTAPGGLQELQLRSLTEILK
GGVLIQRNPQLCHQDTILWEDIFHKNNQLPLKQIDTNRSRACAPCSPACKAPNCWGESSQ
DCQSLTRTVCASGCARCKGPQPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPA
LVTYNTDTFESMPNPEGRYTFGASCVTACPYNYLSTDVGSCTLVCPLNNQEVTAEDGTQR
CEKCSKPCAPVCYGLGMEHLREVRAVTSANIQEFAGCKKIFGSLAFLPESFAGDPDSNIA
PLQAEQLKVFESLEEITGYLYISAWPDSLPDLSVFQNLRVIRGRVLHDGAYSLTLQGLGI
SWLGLRSLRELGSGLALIHRNARLCFVHTVPWDQLFQNPHQALLHSANRPEDECVGEGLA
CYPLCAQGHCWGPGPTQCVNCSQFLRGQECVEVLQGLPREYVKDRYCLPCHPECHPQNGS
VTCFGSEADQCVACAHYKDPPFCVARCPSGVKPDLSFMPIWKFPDEEGICQPCPINCTHS
CVDLDDKGCPAEQRASPVTSIIAAVVGVLLVVLVGLVFGILIKRRRQKIRKYTMRRLLQE
TELVEPLTPSGAMPNQAQMRILKETELRKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIK
VLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQLVTQLMPYGCLLDHVREH
RGRLGSQDLXXWCVQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDID
ETEYHADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPD
LLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVAEFSRMARDPQRFVVIQNED
MGPASPLDSTFYRSLLEDDDMGDLVDAEEYLVPQQGFFCPDPAPGAAGTAHRRHRSTSTR
SGGGELTLGLEPSEEEPPRSPLAPSEGAGSDVFDGDLGMGAAKGLQPLPQHDSSPLQRYS
EDPTVPLSPEADGYVAPLTCSPQPEYVNQPEVHPQPPSPLEGPLPPPRPAGSTLERPKTL
SPGKNGVVKDVFAFGAAVENPEYLAPRGRAAPQSHPSPAFSPAFDNLYYWDQDPSERGTP
PSTFEGTPTAENPEYLGLDMPV
NT seq
3669 nt
NT seq
+upstream
nt +downstream
nt
atgaagctgcggctgccggccagtcccgagacccacctggacatgctgcgccacctctac
caaggctgtcaggtggtgcagggtaacctggagctcacctatctgcctgctgatgccagc
ctctccttcctgcaggaaatccaggaggtgcagggctatgtgctcatcgctcacaatcaa
gtgagtcaggtcccactgcagagactgcgaatcgtgcgaggcacccagctttttgaggaa
cactacgccctggccgtgctggacaatggagactttctggaaagtgctgcccctgctgca
ggcacagccccaggagggctgcaggagctgcagctgcgaagcctcacagagatcctcaag
ggaggggtcttgatccagcggaacccccagctctgccaccaggacacgattttgtgggag
gatatcttccacaagaacaaccagctgcccctcaagcagatagacaccaaccgctcacgg
gcctgcgcaccctgttctccagcttgtaaagctcccaactgctggggagaaagttctcag
gactgtcagagcttgacgcggaccgtctgtgccagtggctgtgcccgctgtaagggccca
cagcccaccgactgctgccatgagcagtgcgctgctggctgtactggccccaagcactct
gactgcctggcctgcctccacttcaaccacagtggcatctgcgagctgcactgcccagct
ctggtcacctacaacacagacaccttcgagtccatgcccaaccccgaggggcgttatacc
ttcggtgccagctgtgtgacggcctgtccttacaactatctgtctacggatgtgggatcc
tgcaccctggtttgtcccctgaacaaccaagaggtgacagctgaggatggaacccagagg
tgtgagaaatgcagcaagccctgtgccccagtgtgctatggtctgggcatggaacacctg
cgggaggtgagggcggtcaccagtgccaacatccaggagtttgccggctgcaagaagatt
tttgggagcctggcgtttctgccagagagctttgcaggggacccagactctaacatcgcc
ccgctgcaggctgagcagctcaaagtgtttgagtctctggaggagatcacaggttacctg
tacatctcagcgtggccagacagcctgcctgacctcagcgtcttccagaacctgcgagta
atccggggacgagttctgcatgatggtgcctactcgctgaccctgcaagggctgggcatc
agctggctggggctgcgctcgctgcgggaactgggcagcgggctggccctcattcaccgc
aacgcccgcctctgcttcgtacacacggtgccctgggaccagctcttccagaacccccac
caggctctgctccacagcgccaacaggccagaggatgagtgcgtgggcgagggcctggcc
tgctatccactgtgcgcccaagggcactgctggggtcccgggcccacccagtgcgtcaac
tgcagccagttccttcggggccaggaatgcgtggaggtactgcaggggctcccccgggag
tacgtgaaggacaggtactgtctgccgtgccaccccgagtgtcatccccagaatggctca
gtgacctgctttggctcggaggctgaccaatgtgtggcttgtgcccactacaaggatcct
cccttctgcgtggctcgctgccccagtggtgtgaagcctgacctctccttcatgcccatc
tggaagtttccagatgaggagggcatatgccagccatgccccatcaactgcacgcactcc
tgtgtggacttggatgacaagggctgccccgccgagcagagagccagccctgtgacatcc
atcattgccgctgtggtgggcgttctgctggttgtccttgtggggctggtgttcggcatc
ctcattaagcgaaggcgccagaagatccggaagtacacgatgcggaggctgctgcaggag
acggagctggtggagcccctgacgcccagcggagcgatgcccaatcaggctcagatgcgg
atcttaaaagagacagagctgaggaaggtgaaggtgctaggatctggagcttttggcacc
gtctacaagggcatctggatccccgatggggaaaatgtgaaaatccccgtggccatcaag
gtgttgagggaaaacacatctcccaaagccaacaaggaaatcttggacgaagcatatgtg
atggctggtgtaggctccccatatgtgtcccgcctcctgggcatctgcctgacatccaca
gtgcagctggtgacacagctgatgccctatggctgcctcttagaccacgttcgagaacac
cgtgggcgcctgggctcccaggacctnnnnnactggtgtgtgcagattgccaaggggatg
agctacttggaggatgtgcggctcgtgcacagggacctggccgcccggaacgtgctggtc
aagagtcccaaccatgtgaagattacagacttcgggctggctcggctgttagacattgac
gagacagagtaccacgcggatgggggcaaggtgcccatcaagtggatggcattggagtcc
attctccggcggcggtttacccaccagagtgacgtgtggagctatggtgtgactgtgtgg
gagctgatgacttttggggccaaaccttatgatgggatcccagcccgggagattcctgac
ctgctggagaagggagaacggctgccccagccccccatctgcaccattgatgtctacatg
atcatggtcaaatgttggatgattgactctgaatgtcggccgaggttccgggagttagtg
gctgaattctcccgcatggccagggacccccagcgctttgtggtcatccagaatgaagac
atggggcctgctagccccctggatagcaccttctaccgctcgctgctggaggatgacgac
atgggcgacctggtggatgcggaggagtacctggtaccccagcagggcttcttctgccca
gaccctgccccgggtgctgcaggcacggcccatcgcaggcaccgcagcacatccaccagg
agtggcggtggtgagctgacactggggctggagccctctgaggaggagcctcccagatct
ccgctggcaccttccgaaggggcaggctctgatgtgtttgatggtgacttgggaatgggg
gcggccaagggactgcagcccctcccccaacatgactctagtcctctgcagcggtacagc
gaggaccccacagtacccctttctcccgaggctgatggctacgttgcccccttgacctgc
agcccccagccggaatatgtgaaccagccagaggttcacccacagcccccctcaccccta
gagggtcctctgccgcctcctcgacctgctggttccactctggaaaggcccaagacgcta
tcccctgggaagaatggggttgtcaaagacgtttttgcctttggggctgccgtggagaac
cctgagtacttggcaccccggggcagggctgcccctcagtcccacccttctccagccttc
agcccagcctttgacaacctctattattgggaccaggacccatcagagcggggcactcca
cccagcacctttgaagggacccctacggcagagaaccctgagtacttgggtctggacatg
ccagtatga
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integrated database retrieval system
