KEGG   Bos mutus (wild yak): 102273017
Entry
102273017         CDS       T02919                                 

Gene name
SOCS3
Definition
(RefSeq) suppressor of cytokine signaling 3
  KO
K04696  suppressor of cytokine signaling 3
Organism
bom  Bos mutus (wild yak)
Pathway
bom04120  Ubiquitin mediated proteolysis
bom04380  Osteoclast differentiation
bom04630  JAK-STAT signaling pathway
bom04668  TNF signaling pathway
bom04910  Insulin signaling pathway
bom04917  Prolactin signaling pathway
bom04920  Adipocytokine signaling pathway
bom04930  Type II diabetes mellitus
bom04931  Insulin resistance
bom04932  Non-alcoholic fatty liver disease
bom04935  Growth hormone synthesis, secretion and action
bom05160  Hepatitis C
bom05164  Influenza A
bom05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:bom00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    102273017 (SOCS3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    102273017 (SOCS3)
   04668 TNF signaling pathway
    102273017 (SOCS3)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    102273017 (SOCS3)
   04920 Adipocytokine signaling pathway
    102273017 (SOCS3)
   04917 Prolactin signaling pathway
    102273017 (SOCS3)
   04935 Growth hormone synthesis, secretion and action
    102273017 (SOCS3)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    102273017 (SOCS3)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    102273017 (SOCS3)
   04932 Non-alcoholic fatty liver disease
    102273017 (SOCS3)
   04931 Insulin resistance
    102273017 (SOCS3)
  09172 Infectious disease: viral
   05160 Hepatitis C
    102273017 (SOCS3)
   05164 Influenza A
    102273017 (SOCS3)
   05168 Herpes simplex virus 1 infection
    102273017 (SOCS3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:bom04121]
    102273017 (SOCS3)
Ubiquitin system [BR:bom04121]
 Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   ECS complex
    Target recognizing subunit (SOCS box)
     102273017 (SOCS3)
SSDB
Motif
Pfam: SH2 SOCS_box
Other DBs
NCBI-GeneID: 102273017
NCBI-ProteinID: XP_005910381
UniProt: L8HMX8
LinkDB
Position
Un
AA seq 229 aa
MVTHSKFPAAGMSRPLDTSLRLKTFSSKSEYQLVVNAVRKLQESGFYWSTVTGGEANLLL
SAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGGSFSLQSDPRSTQPVPRFDCV
LKLVHHYMPAAGAPSFSQPPAEPSSSPSSEVPEQPPAQPLSGNPPRRAYYIYSGGEKIPL
VLSRPLSSNVATLQHLCRKTVNGHLDSYEKVTQLPGPIREFLDQYDAPL
NT seq 690 nt   +upstreamnt  +downstreamnt
atggtcacccacagcaagtttcccgccgccgggatgagccgccccctggacaccagcctg
cgcctcaagaccttcagctccaagagcgagtaccagctggtggtgaacgcagtgcgcaag
ctgcaggagagcggcttttactggagcaccgtgacgggcggcgaagcgaacttgctgctg
agcgccgagcccgcgggcaccttcctcatccgcgacagctcggaccagcgccactttttc
accctcagcgtcaagacccagtcggggaccaagaacctgcgcatccagtgcgaggggggc
agcttctctctccagagcgacccccggagcacgcagcccgtgccccgcttcgactgcgtg
ctcaagctggtgcatcactacatgcccgccgccggcgccccctcgttctcccagcccccc
gctgaaccctcctcctcgccctcctcggaggtgcccgagcagccaccggcccagccgctc
tccgggaacccccccaggagagcctattacatctattcggggggcgagaagatccctctg
gtgttgagccggcccctctcctccaacgtggccactctccaacatctctgtcggaagacc
gtcaacggccacctggactcctacgagaaagtcacccagctgcctgggcccattcgggag
ttcctggaccagtacgatgccccgctttag

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