KEGG   Bos mutus (wild yak): 102283821
Entry
102283821         CDS       T02919                                 

Gene name
PTPN6
Definition
(RefSeq) protein tyrosine phosphatase, non-receptor type 6
  KO
K05697  tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
Organism
bom  Bos mutus (wild yak)
Pathway
bom04520  Adherens junction
bom04630  JAK-STAT signaling pathway
bom04650  Natural killer cell mediated cytotoxicity
bom04660  T cell receptor signaling pathway
bom04662  B cell receptor signaling pathway
bom05140  Leishmaniasis
bom05205  Proteoglycans in cancer
bom05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:bom00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    102283821 (PTPN6)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    102283821 (PTPN6)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    102283821 (PTPN6)
   04660 T cell receptor signaling pathway
    102283821 (PTPN6)
   04662 B cell receptor signaling pathway
    102283821 (PTPN6)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    102283821 (PTPN6)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    102283821 (PTPN6)
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    102283821 (PTPN6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:bom01009]
    102283821 (PTPN6)
Enzymes [BR:bom01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.48  protein-tyrosine-phosphatase
     102283821 (PTPN6)
Protein phosphatases and associated proteins [BR:bom01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Classical)
   Non-receptor PTPs
    102283821 (PTPN6)
SSDB
Motif
Pfam: Y_phosphatase SH2 DSPc Y_phosphatase3 PTPlike_phytase
Other DBs
NCBI-GeneID: 102283821
NCBI-ProteinID: XP_005907552
LinkDB
Position
Un
AA seq 597 aa
MLSHGWFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSG
DFYDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPLNCSDPTSERWYHGHMSGG
QAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVTHIKVMCEGGRYTV
GGSETFDSLTDLVEHFKRTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESEE
TAKAGFWEEFESLQKQEVKNLHQRLEGQRPENKSKNRYKNILPFDHSRVVLQGRDSNIPG
SDYINANYVKNQLLGPDENAKTYIASQGCLEATVNDFWQMVWQENTCVIVMTTREVEKGR
NKCVPYWPEVGSQRVYGPYTVTNCGEHDTTEYKLRNLQVSPLENENLIREIWHYQYLSWP
DHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMESISTKGL
DCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVMQSQKGRESEYGN
ITYPPAMKNAHAKASRTSSKHREDVYENVHSKNKKEEKVKKQRSADKEKNKGSLKRK
NT seq 1794 nt   +upstreamnt  +downstreamnt
atgctgtcccatgggtggtttcaccgagacctcagtgggctggatgcggagaccctgctc
aagggccgaggggtccacggaagcttcctggcacggcccagccgcaagaaccagggtgac
ttctccctctccgtcagggttggggaccaggtgactcatattcggatccagaactctggg
gacttctacgatctgtatggaggggagaagttcgcaacgttgacggagctggtggagtac
tacacgcagcagcagggtgttctacaggatcgagacggcactatcatccacctcaagtac
ccgctgaactgctcagaccccaccagtgagaggtggtaccatggccacatgtctggaggg
caggcagagactttgctgcaggccaagggggagccttggaccttccttgtgcgtgagagc
ctcagccagcctggagattttgtgctgtccgtgctcagcgaccagcccaaggctggcccc
ggctccccgctcagagtcacccatatcaaagtcatgtgtgagggcggacgctacacagtg
gggggttctgagaccttcgacagcctcactgacctggtggagcatttcaagaggacgggg
atcgaggaggcctccggcgctttcgtctacctacggcagccatactatgccacgagggtg
aacgcggctgacattgagaaccgggtcttggaactgaacaagaagcaggagtcagaggag
acagccaaggccggcttctgggaggagtttgagagtctgcagaagcaggaggtgaaaaac
ttgcaccagcggctggaagggcagcggccagaaaacaagagcaagaaccgttacaagaac
atccttccgtttgaccacagtcgagtggtcctgcagggacgcgacagtaacatccctggg
tctgactacattaacgccaactatgtgaagaaccagctgctaggccctgatgagaacgct
aagacctacatcgccagccagggctgcctggaggccacggtcaacgacttctggcagatg
gtgtggcaggagaacacctgcgtcattgtcatgaccacccgggaggtggagaagggccgg
aacaaatgtgttccatactggccagaagtgggcagtcagcgtgtttacggaccctacacc
gtaaccaattgtggggaacacgacacaactgagtacaaactccgaaacttacaggtctcc
ccgctggaaaatgagaacctgattcgggagatttggcactaccagtacctgagctggcct
gatcacggggtccccagtgagcctgggggtgttctcagcttcctggaccagatcaaccag
cggcaggagagtctgcctcacgcagggcccatcatcgtgcattgcagcgccggcatcggc
cgcacgggcaccatcattgtcatcgacatgctcatggagagcatctccaccaagggcctg
gactgtgacatcgacatccagaagaccatccagatggtgcgggcccagcgctcgggcatg
gtgcagacggaggctcagtacaagttcatctacgtggccatcgcccagttcatcgagacc
accaagaagaagttggaggtcatgcagtcccagaagggccgggaatcggaatacgggaac
atcacctacccgccagcaatgaagaacgcccacgccaaggcctcccgcacctcctctaaa
cacagggaggacgtgtatgagaatgtgcacagtaagaacaagaaggaggagaaggtgaag
aaacagcggtcagcagacaaggagaagaacaagggctccttgaagaggaagtga

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