KEGG   Bos taurus (cow): 519357
Entry
519357            CDS       T01008                                 
Symbol
DDB2
Name
(RefSeq) DNA damage-binding protein 2
  KO
K10140  DNA damage-binding protein 2
Organism
bta  Bos taurus (cow)
Pathway
bta03420  Nucleotide excision repair
bta04115  p53 signaling pathway
bta04120  Ubiquitin mediated proteolysis
bta05161  Hepatitis B
bta05169  Epstein-Barr virus infection
bta05200  Pathways in cancer
bta05202  Transcriptional misregulation in cancer
bta05210  Colorectal cancer
bta05212  Pancreatic cancer
bta05213  Endometrial cancer
bta05214  Glioma
bta05216  Thyroid cancer
bta05217  Basal cell carcinoma
bta05218  Melanoma
bta05220  Chronic myeloid leukemia
bta05222  Small cell lung cancer
bta05223  Non-small cell lung cancer
bta05224  Breast cancer
bta05225  Hepatocellular carcinoma
bta05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:bta00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    519357 (DDB2)
  09124 Replication and repair
   03420 Nucleotide excision repair
    519357 (DDB2)
 09140 Cellular Processes
  09143 Cell growth and death
   04115 p53 signaling pathway
    519357 (DDB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    519357 (DDB2)
   05202 Transcriptional misregulation in cancer
    519357 (DDB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    519357 (DDB2)
   05212 Pancreatic cancer
    519357 (DDB2)
   05225 Hepatocellular carcinoma
    519357 (DDB2)
   05226 Gastric cancer
    519357 (DDB2)
   05214 Glioma
    519357 (DDB2)
   05216 Thyroid cancer
    519357 (DDB2)
   05220 Chronic myeloid leukemia
    519357 (DDB2)
   05217 Basal cell carcinoma
    519357 (DDB2)
   05218 Melanoma
    519357 (DDB2)
   05213 Endometrial cancer
    519357 (DDB2)
   05224 Breast cancer
    519357 (DDB2)
   05222 Small cell lung cancer
    519357 (DDB2)
   05223 Non-small cell lung cancer
    519357 (DDB2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    519357 (DDB2)
   05169 Epstein-Barr virus infection
    519357 (DDB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:bta04121]
    519357 (DDB2)
   03400 DNA repair and recombination proteins [BR:bta03400]
    519357 (DDB2)
Ubiquitin system [BR:bta04121]
 Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   Cul4 complex
    Target recognizing subunit (DCAF)
     519357 (DDB2)
DNA repair and recombination proteins [BR:bta03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     Cul4-DDB2 complex
      519357 (DDB2)
SSDB
Motif
Pfam: WD40 NBCH_WD40
Other DBs
NCBI-GeneID: 519357
NCBI-ProteinID: NP_001069256
BGD-bta: BT14135
Ensembl: ENSBTAG00000020999
VGNC: 27942
UniProt: Q0VBY8
LinkDB
Position
15:77097900..77118222
AA seq 426 aa
MAPRKRPENQKTPEVVVRPKSKRNRSPRELEPEAKKLCVKGPGSSRRFDSGLWAGLASLR
VPPLCSSIVRALHQHKLGTAAWPSLQQGLQQSFLNSLASYRIFQKAAPFDRRATSLAWHP
THPSTLAVGSKGGDILLWNFGIKDKPTFIKGIGAGGSITGMKFNPLNTNQFFTSSMEGTT
RLQDFKGNTLRVFASSDTCNVWFCSLDVSVKSRVVVTGDNVGHVILLNMDGRELWNLRMH
KKKVTHVALNPCCDWLLATASVDQTVKIWDLRQVRGKSSFLHSLPHRHPVNAAHFSPDGA
QLLTTDQKSEIRVYSACQWDCPPSLIPHPHRHFQHLTPIKASWHPRYNLIVVGRYPDPNF
KSCSPHELRTIDVFDGSSGKIMYQLYDPESSGIMSLNEFNPMGDTLASVMGYHILVWSPE
DAGTQK
NT seq 1281 nt   +upstreamnt  +downstreamnt
atggctcccaggaaacgcccagaaaaccagaagacccctgaggtggttgtgcgccccaag
agcaagaggaacagaagcccccgggagctggagcccgaggccaagaagctctgtgtgaag
ggccccggttctagcagaagatttgactcaggcctttgggcggggttggctagcctgcgg
gtcccgccgctatgcagcagcatcgtcagggccctccaccagcataagctgggcacagct
gcctggccatcactacagcagggtctccagcagtcttttctgaactctctggcttcttac
cggatattccaaaaggctgccccttttgacaggagggccacatccctggcgtggcaccca
actcaccccagcaccctggctgtgggctccaaagggggagatatcttgctctggaacttt
ggcataaaggacaaacctaccttcattaaagggattggagctggagggagcatcactggg
atgaagtttaaccctctcaataccaaccagtttttcacctcctcaatggagggaacgact
aggctgcaagattttaaaggcaacactctccgagtttttgccagctcagacacctgcaac
gtctggttctgcagcttggacgtatctgtcaaaagccgagtggtggtcacgggagacaat
gtggggcacgtgatcctgctgaacatggatggcagggagctttggaatctgagaatgcac
aaaaagaaggtgacccatgtggccctgaacccgtgctgtgactggctcctggccacagcc
tccgtagatcaaacggtgaaaatctgggacctgcgccaggttagagggaaatccagcttc
ctccactcgctgccgcacaggcatcctgtcaacgcagctcacttcagtcccgatggagcc
cagctcctgactactgaccagaaaagtgagatccgggtttactctgcttgccagtgggac
tgcccgccaagcctgatcccacatcctcaccgccacttccagcacctgacacccatcaag
gcaagctggcatcctcggtacaacctcattgtcgtgggccgatacccagatcctaatttc
aaaagttgttccccccatgaattaaggacgatcgatgtgtttgatggaagctcaggaaag
atcatgtatcagctgtatgacccagaatcttctggtatcatgtcgctcaatgaattcaat
cccatgggggacacgctggcctccgtgatgggttatcacattctcgtttggagcccggag
gatgctgggactcagaaatga

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