KEGG   Bos taurus (cow): 519644
Entry
519644            CDS       T01008                                 

Gene name
CACNA2D3
Definition
(RefSeq) voltage-dependent calcium channel subunit alpha-2/delta-3 precursor
  KO
K04860  voltage-dependent calcium channel alpha-2/delta-3
Organism
bta  Bos taurus (cow)
Pathway
bta04010  MAPK signaling pathway
bta04260  Cardiac muscle contraction
bta04261  Adrenergic signaling in cardiomyocytes
bta04921  Oxytocin signaling pathway
bta05410  Hypertrophic cardiomyopathy
bta05412  Arrhythmogenic right ventricular cardiomyopathy
bta05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:bta00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    519644 (CACNA2D3)
 09150 Organismal Systems
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    519644 (CACNA2D3)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    519644 (CACNA2D3)
   04261 Adrenergic signaling in cardiomyocytes
    519644 (CACNA2D3)
 09160 Human Diseases
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    519644 (CACNA2D3)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    519644 (CACNA2D3)
   05414 Dilated cardiomyopathy
    519644 (CACNA2D3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:bta04040]
    519644 (CACNA2D3)
Ion channels [BR:bta04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   519644 (CACNA2D3)
SSDB
Motif
Pfam: VGCC_alpha2 VWA_N VWA_3 VWA dCache_1 VWA_2 dCache_2 Cache_3-Cache_2 VWA_CoxE Phage_holin_6_1
Other DBs
NCBI-GeneID: 519644
NCBI-ProteinID: NP_001193680
Ensembl: ENSBTAG00000013117
VGNC: 26681
LinkDB
Position
22
AA seq 1091 aa
MARLGWQRRASRGPWALLTAALLYAALGDVVRSEQQIPLSVVKLWASAFGGEIKSIAAKY
SGSQLLQKKYKEYEKDVAIEEIDGLQLVKKLAKNMEEMFHKKSEAVRRLVEAAEEAHLKH
EFDADLQYEYFNAVLINERDKDGNFLELGKEFILAPNDHFNNLPVNISLSDVQVPTNMYN
KDPAIVNGVYWSESLNKVFVDNFDRDPSLIWQYFGSAKGFFRQYPGIKWEPDENGVIAFD
CRNRKWYIQAATSPKDVVILVDVSGSMKGLRMTIAKQTVSSILDTLGDDDFFNIIAYNEE
LHYVEPCLNGTLVQADRTNKEHFREHLDKLFAKGIGMLDIALNEAFNILSDFNHTGQGSI
CSQAIMLITDGAVDTYDTIFAKYNWPDRKVRIFTYLIGREAAFADNLKWMACANKGFFTQ
ISTLADVQENVMEYLHVLSRPKVIDQEHDVVWTEAYIDSTLPQAQKLADDQGPVLMTTVA
MPVFSKQNETRSKGILLGVVGTDVPVKELLKTIPKYKLGIHGYAFAITNNGYILTHPELR
PLYEEGKKRRKPNYSSVDLSEVEWEDRDDVLRNAMVNRKTGKFSMEVKKTVDKGKRVLVM
TNDYYYTDIKGTPFSLGVALSRGHGKYFFRGNVTIEEGLHDLEHPDVSLADEWSYCNTDL
HPEHRHLSQLEAIKLYLKGKEPLLQCDKELIQEVLFDAVVSAPIEAYWTSLALNKSENSD
KGVEVAFLGTRTGLSRINLFVGAEQLTNQDFLKAGDKENIFNADHFPLWYRRAAEQIPGS
FVYSIPFSTGTVNKSNVVTASTSIQLLDERKSPVVAAVGIQMKLEFFQRKFWTASRQCAS
LDGKCSISCDDETVNCYLIDNNGFILVSEDYTQTGDFFGEVEGAVMNKLLTMGSFKRITL
YDYQAMCRANKESSDGAHGLLDPYNAFLAAVKWIMTELVLFLVEFNLCSWWHSDMTAKAQ
KLKQTLEPCDTEYPAFVSERTIKETSGNIACEDCSKSFVIQQIPSSNLFMVVVDSSCLCE
SVAPITMAPIEIRYNESLKCERLKAQKIRRRPESCHGFHPEENARECGGAPNLKAKMVLI
LFPLLLMLFSR
NT seq 3276 nt   +upstreamnt  +downstreamnt
atggccagactgggctggcagcgccgcgcgtcccgggggccctgggcgctcctgaccgcc
gcgcttctctacgccgcgctgggggacgtggtgcgctcggagcagcagatccctctctcc
gtggtgaagctctgggcctctgcttttggtggagagataaaatctattgccgcgaagtac
tccggctcccagcttctgcaaaagaaatacaaagagtatgagaaggatgttgccatagaa
gaaattgatgggctccagctggtgaaaaagctggcaaagaacatggaagagatgtttcac
aagaagtctgaagcagtgcggcgtcttgtggaggctgcagaagaggcgcacctgaaacat
gaatttgatgccgacttacagtatgaatatttcaatgccgtgctaataaatgaaagggac
aaagatgggaactttttggagctggggaaggaattcatcttagccccaaatgaccatttt
aataatctgcctgtgaacatcagtctgagtgacgtccaagtgccaacgaacatgtacaac
aaagatccagcaattgtcaatggagtttactggtccgaatccctaaacaaagtttttgtg
gataactttgatcgtgacccaagtctcatatggcagtactttggaagtgcaaagggcttt
tttaggcagtatccagggattaaatgggaaccagatgagaatggagtcattgcctttgac
tgcaggaaccgaaagtggtacatccaggcagcgacttctccaaaagacgtggtcatttta
gtggatgtcagtggcagcatgaaagggctccgcatgacgatcgcaaagcaaacagtctcg
tctattttggatacgctgggggatgacgacttcttcaacataattgcttataatgaggag
cttcactacgtggaaccttgcctgaatgggacattggtgcaagctgacaggacaaacaaa
gagcacttcagggagcatctggacaaactttttgccaaaggaatcggaatgctggatata
gctctgaatgaagccttcaacattctcagtgatttcaaccacactggacaaggaagcatc
tgcagccaggccattatgctcatcactgacggggcagtggacacctatgacacgatcttt
gccaagtacaactggccagatcgaaaggttcgcatcttcacgtacctcattggacgagag
gctgcttttgcagacaatctcaagtggatggcctgtgccaacaaaggatttttcacccag
atctccaccttggctgacgtgcaggaaaatgtcatggaatacctccatgtactcagccgg
cccaaagtcatcgaccaggagcacgatgtggtgtggactgaagcgtacattgacagcact
ctccctcaggcacaaaagcttgctgatgatcagggccccgtcctgatgaccacggtcgcc
atgcctgtgtttagtaagcagaatgagactagatcaaaaggcattcttctcggtgtggtc
ggcacagatgtcccagtgaaagaacttctgaagaccatccccaaatataagttagggatt
catggctatgcctttgcaatcacaaataatggatatatcctgacgcatccagaactcaga
ccactgtacgaagaaggaaaaaagcggaggaaacccaactacagtagtgtggacctgtct
gaggtggagtgggaggaccgcgatgatgtgttaagaaatgccatggtgaatagaaagacc
gggaagttttccatggaggtgaagaagacagtggacaaagggaaacgggttttggtgatg
acaaatgactactattatacagacatcaagggtactcctttcagtttaggtgtggcgctc
tccagaggccatgggaaatatttcttccgagggaatgtaactattgaagaaggcctgcat
gacttagaacaccctgatgtgtccttggcagacgaatggtcctactgcaacactgaccta
cacccagagcaccgtcatctgtctcagctagaagctattaaactctacctcaaaggcaaa
gaacctctgctccaatgtgataaagaattgatacaggaagtcctttttgatgccgtggtg
agtgctcccattgaagcctattggaccagccttgccctcaacaaatctgagaattcggac
aagggcgtggaggtagccttccttggcactcgcacaggcctctcgagaatcaacctgttt
gttggggcagagcagctcaccaatcaggacttcctgaaagcaggagacaaggagaacatc
tttaatgcagaccatttccctctctggtaccgaagagctgcagagcagattccagggagc
ttcgtctattcgatcccattcagcacaggaacagtcaacaaaagcaatgtggtgacagca
agtacctccatccagcttctggatgaacggaaatctcccgtggtggcagctgtaggcatt
cagatgaaacttgaatttttccaaaggaagttctggactgccagcagacagtgcgcctct
ctggatggcaaatgctcaatcagctgtgacgacgagactgtaaattgttacctcatagac
aataatggatttattctggtatctgaagactacactcagactggagacttttttggtgag
gtggagggagctgtgatgaacaaattgttaacaatgggctcctttaaaagaattaccctt
tatgactatcaagccatgtgcagggccaacaaggagagcagtgacggcgcccacggtctt
ctggatccttataatgccttccttgctgcagtgaaatggataatgacagaacttgtcttg
tttctggtggaatttaacctttgcagttggtggcactcagatatgacagctaaagcccag
aaattgaaacagaccctggagccttgtgacactgaatatccagcgttcgtctctgagcgc
accatcaaggaaacctcagggaacattgcttgtgaagactgctccaagtcctttgtcatc
cagcagatcccgagcagcaatttgttcatggtggtggtggacagcagctgcctctgtgag
tctgtggcccccatcaccatggcacccattgaaatcaggtataatgaatcgcttaagtgt
gaacgtttaaaggcccagaagatcagaaggcgtccggaatcttgtcatggcttccatcct
gaggagaatgcaagggagtgtgggggtgcaccgaatctcaaggccaagatggtcctgatc
ctgttccctctgcttttgatgctcttctcaaggtga

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