KEGG   Bos taurus (cow): 781252Help
Entry
781252            CDS       T01008                                 

Gene name
LIG4
Definition
(RefSeq) DNA ligase 4
  KO
K10777  DNA ligase 4 [EC:6.5.1.1]
Organism
bta  Bos taurus (cow)
Pathway
bta03450  Non-homologous end-joining
Brite
KEGG Orthology (KO) [BR:bta00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03450 Non-homologous end-joining
    781252 (LIG4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:bta03400]
    781252 (LIG4)
Enzymes [BR:bta01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.1  DNA ligase (ATP)
     781252 (LIG4)
DNA repair and recombination proteins [BR:bta03400]
 Eukaryotic Type
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    DNA Ligase 4 complex
     781252 (LIG4)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: DNA_ligase_A_M DNA_ligase_A_N DNA_ligase_A_C DNA_ligase_IV BRCT BRCT_2 RNA_ligase mRNA_cap_enzyme APG17
Motif
Other DBs
NCBI-GeneID: 781252
NCBI-ProteinID: NP_001178055
BGD-bta: BT20764
Ensembl: ENSBTAG00000015868
VGNC: 30884
UniProt: F1MB07
LinkDB All DBs
Position
12
AA seq 911 aa AA seqDB search
MAASQTSQTVASHVPFADLCSTLERIQKSKGRAEKIRHFKAFLDSWRKFHNALHKNQKDV
TDSFYPAMRLILPQLERERMAYGIKETMLAKLYIELLNLPRDGKDALKLLNYRTPTGTRG
DAGDFAMIAYFVLKPRCLQKGSLSIQQVNDILDSIASNNSAKRKDLMKKSVLQLITQSSA
LEQKWLIRMIVKDLKLGFSQQTIFSIFHSDAAELHNVTTDLEKVCRQLHDPSVGLSDISI
TLFSAFKPMLAAIADIERIEKDMKHQSFYIETKLDGERMQMHKDGDVYRYFSRNGYNYVD
QFGASPQEGSLTPFIHNAFKTEVLNCILDGEMMAYNPNTQTFMQKGNKFDIKRMVEDSEL
QTCYCVFDVLMVNDKKLGHETLRKRYEILNSVFTPVPGRIEIVQKTQAHTKKEVIDALNE
AIDKREEGIMVKHPLSIYKPDKRGEGWLKIKPEYVNGLMDELDILIIGGYWGKGARGGMM
SHFLCAVSEKPPSGEKPSVFHTLCRVGSGYTMKELYDLGLKLAKHWKPFHRKAPPSNILC
GTEKPEVYIEPCNSVIVQVKATEIVPSDMYKTGCTLRFPRIEKIREDKEWYECTSLEDLE
QLRGKACGKLASRHLYLGGDDEPQEKKRKAAPKMKKVIGIIEHLKAPNLSNVNRVSTVFE
DVEFCVMSGTSSHPKPDLENRIAELGGYIVQNPGPDTYCVIAGSENIRVKNIISSDKHDV
VKPEWLLECFRTRSCVPWQPRFMIHMCPSTKQHFAQEYDQYGDSYFVDTDLHQLKEVFLG
IKNAGEQTPGEMSPVIADLEHRYSWASAPLSMFRHLTVYLDLYAVINDLSTRIKGARLAI
TALELRFHGAQVVSCLAEGVSHVIVGEDQSRVADLKAIRRTLKRKFKILQERWVTVSIDK
CELQEENRYLV
NT seq 2736 nt NT seq  +upstreamnt  +downstreamnt
atggctgcctcacaaacctcacaaactgttgcatctcatgttccttttgcagatttatgt
tcgactttagaacgaatacagaaaagtaaagggcgtgcagaaaaaatcagacacttcaaa
gcatttttagattcttggagaaaatttcacaatgcccttcataagaaccaaaaagatgtc
acagattctttttatccagccatgagacttattcttcctcagctggaaagagagagaatg
gcctacggaatcaaagaaactatgctggctaagctttatattgaattgcttaacctgcct
cgagatggaaaagatgcccttaaacttttgaactacagaacaccgaccggaacccgtgga
gatgctggagactttgcaatgattgcgtactttgtactgaaacccaggtgtctacagaaa
ggaagcctaagcattcagcaagtaaatgacattttagactccattgccagcaataattct
gccaaaaggaaagacctaatgaagaagagtgttcttcagcttataactcagagttcagca
cttgaacaaaagtggctgatacggatgattgttaaggacctaaagcttggctttagtcag
caaactatattttctatttttcacagtgatgctgccgagttgcataatgtcaccacagat
ctggagaaggtctgtaggcaactacacgatccttcagtgggactcagtgacatttccatc
accttattctctgcctttaaacccatgctggccgctatagcagatatcgagcgaattgag
aaggacatgaaacaccagagtttctacatcgaaaccaagctggatggcgagcggatgcag
atgcacaaggatggggatgtgtaccggtacttctctcgcaatgggtataactatgtagac
cagtttggtgcttccccacaggaagggtccctcacaccattcattcataatgcattcaaa
acagaagtgctgaactgtatcctcgatggtgagatgatggcctacaaccctaacacacaa
acttttatgcaaaaggggaataagtttgacattaaaagaatggtggaagattctgagctg
cagacttgttactgtgtttttgatgtgttgatggttaatgataaaaaactaggacatgag
accctgagaaagaggtatgaaattcttaatagtgttttcacacctgtaccaggtagaata
gaaatagtgcagaaaacacaagctcatactaagaaagaagtcattgatgctttgaatgaa
gcgatagataaaagagaagaggggatcatggtaaaacacccgctgtccatttacaagccg
gataaaagaggtgaaggatggttaaaaattaaaccagagtatgtcaatggactgatggat
gagctggacatcttaatcatcgggggctactgggggaagggtgcccggggcgggatgatg
tctcattttttgtgcgctgtgtcagagaagcccccttctggtgaaaaaccctcagtgttt
catactctgtgtcgcgtgggctcgggttacaccatgaaagaactgtatgacctgggtttg
aagttggccaaacactggaagccttttcataggaaagccccaccaagcaacattctatgt
ggaacagagaagccagaggtctacatcgagccttgcaattcagtcattgttcaggttaag
gccacagagatcgtccccagtgacatgtataaaaccggctgcacgttgcgttttccacgg
attgagaagataagagaagacaaagaatggtacgaatgtacatccctggaggacttagag
caacttcgagggaaagcctgtggaaagctcgcgtccagacacctttacttgggtggtgat
gatgaaccacaagagaaaaagcggaaagctgccccaaagatgaagaaagtcattggaatt
attgagcacctaaaagctcccaacctttctaacgtaaacagggtttctactgtgtttgaa
gacgtggagttttgtgtcatgagtggaaccagcagccatcccaagcctgacctggagaac
agaattgccgaattgggtggttacatagtacagaacccaggcccagacacgtactgtgtg
atcgcagggtctgagaacattcgagtgaagaatatcatctcttcagataaacatgatgtc
gtcaagccagagtggctgctagagtgttttaggaccagaagctgtgtgccctggcaaccc
cgcttcatgatccacatgtgcccgtcgacaaagcagcacttcgcccaggaatacgaccaa
tacggggatagttactttgtcgacacagatttgcaccaactgaaggaagtgtttttggga
attaaaaacgctggtgagcagactccaggggagatgagtcctgtgattgctgatttggaa
cacaggtattcctgggccagtgcacctcttagcatgtttagacacctcactgtttatttg
gacctgtacgctgtcatcaatgacttaagtaccagaatcaagggagctaggttagccatc
acagccttggagcttcgatttcatggagcgcaagtagtttcctgtttagctgagggagtg
tctcacgtgattgttggggaggatcagagtcgggttgcagacttgaaagctattcgaagg
actcttaagaggaaatttaaaatcttacaagaacgttgggtcactgtttcaatagacaag
tgtgaattacaggaggaaaatcggtatttggtttga

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