Clostridium botulinum E3: CLH_2648
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Entry
CLH_2648 CDS
T00767
Name
(GenBank) uroporphyrinogen III synthase/methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
cbt
Clostridium botulinum E3
Pathway
cbt00860
Porphyrin metabolism
cbt01100
Metabolic pathways
cbt01110
Biosynthesis of secondary metabolites
cbt01120
Microbial metabolism in diverse environments
cbt01240
Biosynthesis of cofactors
Module
cbt_M00924
Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide
Brite
KEGG Orthology (KO) [BR:
cbt00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
CLH_2648
Enzymes [BR:
cbt01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
CLH_2648
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
CLH_2648
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Paralog
Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
ACD53674
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Position
complement(2802372..2803847)
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AA seq
491 aa
AA seq
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MNKVYIIGTGPGDEELLTVKAVNKLKECTAVLYDRLVSNNILNYLSDSCEIYYCGKEPGA
HYKTQEEINEMLVKLAKEGHVVGRVKGGDPYVFGRGGEEVLALKEENIPFEVIPGVTSPI
AVLNYAGIPITHRGIAQSFHVVTGMSAKHIKSNFKALAMEEGTLVFMMGLSNLENIVHEL
VLNGKDISTPCGVVMRGTSSKQKKVVGTLENICKKVEEAKLQSPCIIVIGEVVNLNEDLA
WYEHKPLFGKNICVTRSQKQAATLKQKLRDMGAEVTALSAIEIESTANNLDSYMGDLENY
DHIVFTSVNSVDIFFDYLIENKYDIRKLQAKVSAIGKATWQALERRGIICFVKAREFIGA
GLIKVLKPHVKENEKVLIPCSSLAKSDIADELSNVGANVDRVFIYDTVKGRVRNKRAFDE
VDIVFFTSPSTVYNMIDMVGLDAIKEKQVIAIGTRTNKPLEELGIKAYICKEHSQDGFLN
EIESFVKDMEA
NT seq
1476 nt
NT seq
+upstream
nt +downstream
nt
atgaataaagtatatattataggtacaggacctggagacgaagaattattaaccgtaaaa
gctgtgaataaattaaaagagtgtacagctgttttatatgatagattggtttcaaataat
attttaaattatttaagtgattcttgtgaaatttattattgtggaaaagaaccaggagca
cattataaaacacaagaagaaataaatgaaatgctagtaaaattagcaaaagaaggccat
gtagtgggaagagttaaaggcggagacccttatgtttttggaagaggaggagaagaggtg
ttagcgcttaaggaagaaaatattccttttgaagtaataccaggagtaacttctccaata
gcagtattaaattatgcaggtattccaataactcataggggaatagctcaaagttttcat
gttgtaactggaatgtcagcaaaacatattaagtctaatttcaaagcattagctatggaa
gaaggaactttagtatttatgatgggattaagcaacttagaaaacatagtacatgaactt
gtgttaaatggaaaagatatttctacaccttgtggcgttgttatgagaggaacttctagt
aagcaaaagaaggtagttggaactttagaaaatatatgtaaaaaagtagaagaagctaaa
ttacaatcaccatgtataattgttatcggtgaagtggttaatttaaatgaagacttagct
tggtatgaacataaacctttgtttggcaaaaatatttgtgtaactagatctcaaaagcaa
gcggctactttaaaacaaaagttaagagatatgggcgctgaagttacggctttaagtgct
atagaaatagaaagtacagctaataatttagatagctatatgggtgatttagaaaattat
gatcatatagtatttacctctgtgaattcagttgatatattctttgattatttaatagaa
aataaatatgatataagaaaattacaagctaaagtatcagctataggtaaagcaacatgg
caagctcttgaaagaagaggtataatatgttttgtgaaagctagagaatttataggcgct
ggattaataaaagtattaaaaccacatgttaaagaaaatgaaaaggtacttattccatgt
tcatcattagcaaagtcagatatagcagatgaattatctaatgtaggtgctaatgtagat
agagtatttatttatgatacagtaaaaggaagagtaagaaataaaagagcatttgatgaa
gtagatatagtattttttacaagcccatcaactgtatataatatgatagatatggttgga
ttagatgctattaaagaaaaacaagttatagcaataggcactagaactaataaaccactt
gaagaactaggaataaaggcatatatttgcaaggagcattcacaagacggattcttaaat
gaaattgaatcatttgtaaaagatatggaggcgtaa
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