KEGG   Castor canadensis (American beaver): 109685239Help
Entry
109685239         CDS       T04791                                 

Gene name
Hk1
Definition
(RefSeq) hexokinase-1
  KO
K00844  hexokinase [EC:2.7.1.1]
Organism
ccan  Castor canadensis (American beaver)
Pathway
ccan00010  Glycolysis / Gluconeogenesis
ccan00051  Fructose and mannose metabolism
ccan00052  Galactose metabolism
ccan00500  Starch and sucrose metabolism
ccan00520  Amino sugar and nucleotide sugar metabolism
ccan00524  Neomycin, kanamycin and gentamicin biosynthesis
ccan01100  Metabolic pathways
ccan01200  Carbon metabolism
ccan04066  HIF-1 signaling pathway
ccan04910  Insulin signaling pathway
ccan04930  Type II diabetes mellitus
ccan04973  Carbohydrate digestion and absorption
ccan05230  Central carbon metabolism in cancer
Module
ccan_M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
ccan_M00549  Nucleotide sugar biosynthesis, glucose => UDP-glucose
Brite
KEGG Orthology (KO) [BR:ccan00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    109685239 (Hk1)
   00051 Fructose and mannose metabolism
    109685239 (Hk1)
   00052 Galactose metabolism
    109685239 (Hk1)
   00500 Starch and sucrose metabolism
    109685239 (Hk1)
   00520 Amino sugar and nucleotide sugar metabolism
    109685239 (Hk1)
  09110 Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    109685239 (Hk1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    109685239 (Hk1)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    109685239 (Hk1)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    109685239 (Hk1)
 09160 Human Diseases
  09161 Cancers
   05230 Central carbon metabolism in cancer
    109685239 (Hk1)
  09166 Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    109685239 (Hk1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ccan04131]
    109685239 (Hk1)
Enzymes [BR:ccan01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.1  hexokinase
     109685239 (Hk1)
Membrane trafficking [BR:ccan04131]
 Autophagy
  Mitophagy
   Other mitophagy associated  proteins
    109685239 (Hk1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Hexokinase_2 Hexokinase_1 CSD Glycos_transf_2
Motif
Other DBs
NCBI-GeneID: 109685239
NCBI-ProteinID: XP_020017566
UniProt: A0A250Y5Y9
LinkDB All DBs
Position
Unknown
AA seq 916 aa AA seqDB search
MIAAQLLAYYFTELKDDQVKKIDKYLFAMRLSDETLIDIMMRFKREMQNGLSRDFNPTAT
VKMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRVQVNHEKNQNVHMESEAYDTPENIVH
GSGSQLFDHVAECLGDFMEKRKIKDKKLPVGFTFSFPCQQSKIDEAVLITWTKRFKASGV
EGADVVKLLDKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYME
ELRHIDLVEGDEGRMCINTEWGAFGDDGSLEDIRTEFDRELDRGSLNPGKQLFEKMVSGM
YLGELVRLILVKMAKEGLLFEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLG
VEPSDDDCISVQHVCTIVTFRSANLVAATLSAILNRLRDNKGTPRLRTTVGVDGSLYKTH
PQYARRFHKTLRRLVPDTDVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLT
KQMLLEVKRRMREEMETGLRKATNDKAVVKMLPSFVRSTPDGTEHGDFLALDLGGTNFRV
LLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGF
TFSFPCKQTSLDAGILVTWTKGFKATDCVGHDVATLLRDAIKRREEFDLDVVAMVNDTVG
TMMTCAYEEPSCEIGLIVGTGCNACYMEEMKNIEMVEGDQGQMCINMEWGAFGDNGCLDD
IRTEYDRLVDEFSLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISEPLKTRG
IFETKFLSQIESDRLALLQVRTILQQLGLNSTCDDSILVKTVCGVVSKRAAQLCGAGMAA
VVDKIRENRGLDHLNVTVGVDGTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKG
AALITAVGVRLREASS
NT seq 2751 nt NT seq  +upstreamnt  +downstreamnt
atgatcgccgcgcagctcctggcctattacttcaccgagctcaaggatgaccaagtcaaa
aagattgacaagtatctgtttgccatgcggctctccgatgaaactctgatagatattatg
atgcgcttcaagagggaaatgcagaatggcctctcccgagattttaatccgacagccacg
gtgaagatgttgccaacctttgtaaggtccattcctgatggttcagaaaagggagatttc
atagccctggatcttggcgggtcttcttttcgaattctgcgggtacaagtgaatcacgag
aagaaccagaatgttcacatggagtcagaggcttatgacaccccagagaatattgttcat
ggcagtggaagccagctctttgatcatgtcgctgagtgcctgggggacttcatggagaaa
aggaagatcaaggacaagaaattgcctgtgggattcacgttttccttcccttgccagcag
tccaaaatagacgaggcagtcctgatcacatggaccaagcggtttaaagccagtggtgtg
gaaggggcagatgtggtcaaactcctggacaaagccatcaagaagcgaggggactatgat
gccaacattgtagctgtggtgaacgacacggtggggaccatgatgacctgtggctatgat
gaccagcactgtgaagtcggactgatcattgggactggcaccaacgcttgctacatggag
gaactgaggcacatcgacctggtggaaggtgacgaggggaggatgtgcatcaacaccgag
tggggggcctttggggatgacgggtccctggaagatatccgcaccgagtttgacagagag
ctggaccgggggtccctcaaccctggaaagcagctgtttgagaagatggtcagcggcatg
tacctgggggagctggtccgcctcatcctggtcaagatggccaaagagggcctcttattt
gaagggcggatcaccccggagctgctcacgagggggaagtttaacaccagtgatgtgtca
gccatagaaaagaataaggaaggcctccacaatgccaaagagatcctgacccgcctggga
gtggaaccatctgatgacgactgtatttcagtccagcatgtatgcaccattgtcacgttt
cgctcggccaacctggtggctgctacactgagtgccatcctgaatcgtcttcgtgataac
aaaggcacgcccaggctgcggaccacggttggtgtggacggctctctttacaagacgcac
ccacagtatgcccggcgtttccacaagaccctgaggcgcctggtgcccgacaccgatgtg
cgcttcctcctctcggagagtggcagtggcaagggggccgctatggtgaccgcggtggcc
taccgtctggctgagcagcatcggcagatagaggagaccctggcccacttccacctcacc
aagcagatgcttttggaggtgaagaggaggatgcgggaggagatggagacagggctgagg
aaggcgacaaacgataaggctgtggtcaagatgctgccttcctttgtccggagcacgcca
gacgggactgagcatggtgacttcttggccctggatcttggaggaacgaatttccgtgtc
ctgctggtgaaaattcgtagtgggaaaaagagaacggtggaaatgcacaacaagatctat
gccattcccattgagatcatgcagggtactggggaagagctttttgaccacatcgtctcc
tgcatctccgacttcctggactacatggggataaaaggcccccgaatgcctttgggcttt
actttctcatttccctgcaagcagacaagtctggatgcgggaatcctggttacctggacc
aagggttttaaggcaactgactgtgtgggtcacgatgtagccaccttactgagagatgca
ataaaaaggagagaggaatttgacctggatgtggtggctatggtcaatgacacagtgggc
actatgatgacctgtgcttatgaggagccctcgtgtgagattggacttatcgtagggacg
ggttgcaatgcctgctacatggaggaaatgaagaacattgagatggtggagggggaccag
ggacaaatgtgcatcaacatggagtggggtgcctttggagacaatgggtgtctggatgat
atcagaactgaatatgacagattggtggatgaattctctctaaacgctgggaagcaaagg
tatgagaagatgatcagtggtatgtacctgggtgaaatcgtccgcaacattctcatcgac
ttcaccaaaaagggattcctcttccgagggcagatctctgaaccactcaagacccggggc
atctttgagaccaagtttctctctcagattgagagtgaccgattagcgctgctccaggtc
cggaccatcctccagcagttgggtttgaacagcacatgtgacgacagcatcctggtcaag
actgtgtgtggggtggtgtccaagagggctgcacagctgtgtggcgcaggcatggctgca
gtggtggacaagatccgagagaacagagggctggaccatctgaatgtgaccgtgggagtg
gacgggacgctctacaagcttcatccacacttctccagaatcatgcaccaaaccgtgaag
gagctgtcaccaaagtgtaacgtgtcctttctcctgtctgaggacggtagtggcaagggg
gctgccctcatcacagccgtgggtgtgcggctccgagaagcgagcagttaa

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