KEGG   Castor canadensis (American beaver): 109687324
Entry
109687324         CDS       T04791                                 

Gene name
Stat3
Definition
(RefSeq) signal transducer and activator of transcription 3 isoform X1
  KO
K04692  signal transducer and activator of transcription 3
Organism
ccan  Castor canadensis (American beaver)
Pathway
ccan01521  EGFR tyrosine kinase inhibitor resistance
ccan04062  Chemokine signaling pathway
ccan04066  HIF-1 signaling pathway
ccan04068  FoxO signaling pathway
ccan04217  Necroptosis
ccan04550  Signaling pathways regulating pluripotency of stem cells
ccan04630  JAK-STAT signaling pathway
ccan04659  Th17 cell differentiation
ccan04917  Prolactin signaling pathway
ccan04920  Adipocytokine signaling pathway
ccan04931  Insulin resistance
ccan04933  AGE-RAGE signaling pathway in diabetic complications
ccan04935  Growth hormone synthesis, secretion and action
ccan05145  Toxoplasmosis
ccan05160  Hepatitis C
ccan05161  Hepatitis B
ccan05162  Measles
ccan05163  Human cytomegalovirus infection
ccan05167  Kaposi sarcoma-associated herpesvirus infection
ccan05169  Epstein-Barr virus infection
ccan05200  Pathways in cancer
ccan05203  Viral carcinogenesis
ccan05205  Proteoglycans in cancer
ccan05206  MicroRNAs in cancer
ccan05212  Pancreatic cancer
ccan05221  Acute myeloid leukemia
ccan05223  Non-small cell lung cancer
ccan05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ccan05321  Inflammatory bowel disease
Brite
KEGG Orthology (KO) [BR:ccan00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    109687324 (Stat3)
   04066 HIF-1 signaling pathway
    109687324 (Stat3)
   04068 FoxO signaling pathway
    109687324 (Stat3)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    109687324 (Stat3)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    109687324 (Stat3)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    109687324 (Stat3)
   04062 Chemokine signaling pathway
    109687324 (Stat3)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    109687324 (Stat3)
   04917 Prolactin signaling pathway
    109687324 (Stat3)
   04935 Growth hormone synthesis, secretion and action
    109687324 (Stat3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    109687324 (Stat3)
   05206 MicroRNAs in cancer
    109687324 (Stat3)
   05205 Proteoglycans in cancer
    109687324 (Stat3)
   05203 Viral carcinogenesis
    109687324 (Stat3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    109687324 (Stat3)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    109687324 (Stat3)
   05221 Acute myeloid leukemia
    109687324 (Stat3)
   05223 Non-small cell lung cancer
    109687324 (Stat3)
  09163 Immune disease
   05321 Inflammatory bowel disease
    109687324 (Stat3)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    109687324 (Stat3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    109687324 (Stat3)
  09172 Infectious disease: viral
   05162 Measles
    109687324 (Stat3)
   05161 Hepatitis B
    109687324 (Stat3)
   05160 Hepatitis C
    109687324 (Stat3)
   05163 Human cytomegalovirus infection
    109687324 (Stat3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    109687324 (Stat3)
   05169 Epstein-Barr virus infection
    109687324 (Stat3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    109687324 (Stat3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    109687324 (Stat3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:ccan03000]
    109687324 (Stat3)
Transcription factors [BR:ccan03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    109687324 (Stat3)
SSDB
Motif
Pfam: STAT_alpha STAT_bind STAT_int SH2 E2R135 DUF4795 Syntaxin-6_N AP1AR Fib_alpha
Other DBs
NCBI-GeneID: 109687324
NCBI-ProteinID: XP_020020742
LinkDB
Position
Unknown
AA seq 770 aa
MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNL
LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAA
TAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLK
SQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEEL
ADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQ
HRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNY
QLKIKVCIDKDSGEVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGN
GGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWY
NMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYS
GCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILST
KPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIM
DATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGSAAPYLKTKFICVTPTTCSN
TIDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMELTSECSTSPM
NT seq 2313 nt   +upstreamnt  +downstreamnt
atggcccaatggaatcagttacagcagcttgacacacggtacctggagcagcttcatcag
ctgtacagcgacagcttcccaatggagttacggcaatttctggcaccttggattgagagt
caagattgggcatatgcagccagcaaagagtcacatgccacactggtgtttcataatctt
ctgggtgagatcgaccagcagtatagccgcttcctgcaagagtccaacgttctctatcag
cacaatctgcgaagaatcaagcagttcctccagagcaggtatcttgagaagccaatggaa
attgcccggattgtggcccggtgcctgtgggaagagtcccgccttctgcagacagcagcc
actgcagcccagcaagggggccaggccaaccaccctacagctgctgtggtgacagagaag
cagcagatgctggagcaacaccttcaggatgttcggaagcgcgtacaggatttagaacag
aaaatgaaagtggtagagaatcttcaggatgactttgatttcaactataaaaccctcaag
agtcaaggagacatgcaggatctgaatggaaacaaccagtctgtgactaggcagaagatg
cagcagctggaacagatgctcacagcactggaccagatgcggagaagcatcgtgagtgag
ctggcagggcttttgtcagcaatggagtatgtgcaaaaaactctcacggatgaagagttg
gctgactggaagaggcgacaacagattgcatgcattggaggccctcccaacatctgcctg
gatcgtctggagaactggataacctcattagcagaatctcaacttcagacccgccaacaa
attaagaaactagaggagttacagcaaaaagtttcctacaaaggggaccccatcgtacag
caccggccaatgctggaggagagaattgtggagctgtttagaaacttaatgaaaagtgcc
tttgtggttgaacggcaaccctgcatgcccatgcatcctgaccggcccctagtcatcaag
accggtgtccagtttaccactaaagtcaggttgctggtcaaatttcctgagttgaattat
cagcttaaaattaaagtgtgcattgacaaagactctggggaggttgcagctctcagagga
tcccggaaatttaacattctgggcacaaacacaaaagtgatgaacatggaagagtctaac
aacggcagcctctctgcagaattcaagcacttgaccctcagggagcaaagatgtgggaat
ggaggccgtgccaattgtgatgcctccctgattgtgaccgaggagctgcacctgatcacc
ttcgagacagaggtgtaccaccaaggcctcaagattgacctagagacccactccttgcca
gttgtggtgatctccaacatctgtcagatgccaaatgcttgggcatccatcctgtggtat
aacatgctgaccaacaaccccaagaacgtgaatttcttcaccaagcccccaattggaacc
tgggatcaagtggctgaagtgctgagctggcaattctcttctaccacaaagcgaggcctg
agcatcgagcagttgaccacactggcggagaaactcttaggacctggtgtgaactactca
gggtgtcagatcacatgggctaagttttgcaaagaaaacatggctggcaagggcttttcc
ttctgggtctggctggacaatatcatcgaccttgtgaaaaagtatatcctggccctttgg
aacgaaggttacataatgggcttcatcagcaaggagagggagcgggccatcctgagcacc
aagcccccaggcaccttcctgctgagattcagtgaaagcagcaaggaaggaggagtcacc
ttcacttgggtggagaaggacatcagtggcaagacccagatccagtcggtggagccatat
acaaagcaacagctgaacaacatgtcctttgctgaaatcatcatgggctataagatcatg
gatgctaccaacatcctcgtgtctccattggtctatctttaccctgacattcctaaggag
gaggcatttggaaagtactgtcgacccgagagccaggagcatcctgaagctgacccaggt
agtgctgccccatacctaaagaccaagttcatctgtgtgacaccaacgacctgcagcaat
accattgacctgccgatgtccccccgcactttagattcattgatgcagtttggaaataat
ggtgaaggtgctgagccctcagcaggagggcagtttgagtcgctcacctttgacatggag
ttgacctcggagtgctctacctcccccatgtga

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