KEGG   PATHWAY: cck02030
Entry
cck02030                    Pathway                                

Name
Bacterial chemotaxis - Clostridium carboxidivorans
Description
Chemotaxis is the process by which cells sense chemical gradients in their environment and then move towards more favorable conditions. In chemotaxis, events at the receptors control autophosphorylation of the CheA histidine kinase, and the phosphohistidine is the substrate for the response regulator CheY, which catalyzes the transfer of the phosphoryl group to a conserved aspartate. The resulting CheY-P can interact with the switch mechanism in the motor. This interaction causes a change in behavior, such as in direction or speed of rotation of flagella.
Class
Cellular Processes; Cell motility
Pathway map
cck02030  Bacterial chemotaxis
cck02030

Other DBs
GO: 0006935
Organism
Clostridium carboxidivorans [GN:cck]
Gene
Ccar_02165  hypothetical protein [KO:K03406]
Ccar_06015  chemotaxis protein [KO:K03406]
Ccar_11335  chemotaxis protein [KO:K03406]
Ccar_11365  chemotaxis protein [KO:K03406]
Ccar_12415  chemotaxis protein [KO:K03406]
Ccar_06875  chemotaxis protein [KO:K03406]
Ccar_07045  chemotaxis protein [KO:K03406]
Ccar_12625  hypothetical protein [KO:K03406]
Ccar_02395  chemotaxis protein [KO:K03406]
Ccar_02625  hypothetical protein [KO:K03406]
Ccar_07830  chemotaxis protein [KO:K03406]
Ccar_11465  chemotaxis protein [KO:K03406]
Ccar_07955  chemotaxis protein [KO:K03406]
Ccar_08410  chemotaxis protein [KO:K03406]
Ccar_08420  chemotaxis protein [KO:K03406]
Ccar_08425  chemotaxis protein [KO:K03406]
Ccar_04060  chemotaxis protein [KO:K03406]
Ccar_08565  chemotaxis protein [KO:K03406]
Ccar_08660  chemotaxis protein [KO:K03406]
Ccar_08750  chemotaxis protein [KO:K03406]
Ccar_08790  chemotaxis protein [KO:K03406]
Ccar_08810  chemotaxis protein [KO:K03406]
Ccar_04615  chemotaxis protein [KO:K03406]
Ccar_04845  hypothetical protein [KO:K03406]
Ccar_09580  chemotaxis protein [KO:K03406]
Ccar_09770  chemotaxis protein [KO:K03406]
Ccar_05380  methyl-accepting transducer [KO:K03406]
Ccar_05465  chemotaxis protein [KO:K03406]
Ccar_09960  chemotaxis protein [KO:K03406]
Ccar_10020  chemotaxis protein [KO:K03406]
Ccar_10025  hypothetical protein [KO:K03406]
Ccar_05755  chemotaxis protein [KO:K03406]
Ccar_05795  hypothetical protein [KO:K03406]
Ccar_01915  chemotaxis protein [KO:K03406]
Ccar_01970  chemotaxis protein [KO:K03406]
Ccar_02060  chemotaxis protein [KO:K03406]
Ccar_02100  chemotaxis protein [KO:K03406]
Ccar_02115  chemotaxis protein [KO:K03406]
Ccar_01395  hypothetical protein [KO:K03406]
Ccar_01470  chemotaxis protein [KO:K03406]
Ccar_00315  hypothetical protein [KO:K03406]
Ccar_23375  chemotaxis protein [KO:K03406]
Ccar_23505  chemotaxis protein [KO:K03406]
Ccar_14425  chemotaxis protein [KO:K03406]
Ccar_14930  chemotaxis protein [KO:K03406]
Ccar_24005  chemotaxis protein [KO:K03406]
Ccar_15325  hypothetical protein [KO:K03406]
Ccar_15685  hypothetical protein [KO:K03406]
Ccar_16380  hypothetical protein [KO:K03406]
Ccar_17645  chemotaxis protein [KO:K03406]
Ccar_13475  chemotaxis protein [KO:K03406]
Ccar_13740  chemotaxis protein [KO:K03406]
Ccar_09245  chemotaxis protein [KO:K03406]
Ccar_08325  LacI family transcriptional regulator [KO:K10439]
Ccar_03005  LacI family transcriptional regulator [KO:K10439]
Ccar_20310  D-ribose transporter subunit RbsB [KO:K10439]
Ccar_24965  chemotaxis protein CheA [KO:K03407] [EC:2.7.13.3]
Ccar_13750  chemotaxis protein CheA [KO:K03407] [EC:2.7.13.3]
Ccar_01465  chemotaxis protein CheW [KO:K03408]
Ccar_24945  chemotaxis protein CheW [KO:K03408]
Ccar_24980  chemotaxis protein CheW [KO:K03408]
Ccar_13745  chemotaxis protein CheW [KO:K03408]
Ccar_11660  histidine kinase [KO:K03413]
Ccar_02655  histidine kinase [KO:K03413]
Ccar_08395  histidine kinase [KO:K03413]
Ccar_08400  histidine kinase [KO:K03413]
Ccar_05770  histidine kinase [KO:K03413]
Ccar_09735  chemotaxis protein CheY [KO:K03413]
Ccar_24770  chemotaxis protein CheY [KO:K03413]
Ccar_24975  chemotaxis protein CheY [KO:K03413]
Ccar_24970  chemotaxis protein CheY [KO:K03410]
Ccar_14510  chemotaxis protein CheX [KO:K03409]
Ccar_24955  chemotaxis protein CheY [KO:K03412] [EC:3.1.1.61 3.5.1.44]
Ccar_13730  chemotaxis protein [KO:K03412] [EC:3.1.1.61 3.5.1.44]
Ccar_08060  chemotaxis protein CheV [KO:K03415]
Ccar_24950  chemotaxis protein CheD [KO:K03411] [EC:3.5.1.44]
Ccar_24960  chemotaxis protein CheR [KO:K00575] [EC:2.1.1.80]
Ccar_13735  chemotaxis protein CheR [KO:K00575] [EC:2.1.1.80]
Ccar_25215  flagellar motor switch protein FliG [KO:K02410]
Ccar_24985  flagellar motor switch protein FliM [KO:K02416]
Ccar_24990  flagellar motor switch protein [KO:K02417]
Ccar_21150  flagellar motor protein MotA [KO:K02556]
Compound
C00049  L-Aspartate
C00107  Dipeptide
C00121  D-Ribose
C00124  D-Galactose
C00208  Maltose
C00716  Serine
Reference
  Authors
Kristich CJ, Ordal GW.
  Title
Bacillus subtilis CheD is a chemoreceptor modification enzyme required for chemotaxis.
  Journal
J Biol Chem 277:25356-62 (2002)
DOI:10.1074/jbc.M201334200
Reference
  Authors
Kirby JR, Kristich CJ, Saulmon MM, Zimmer MA, Garrity LF, Zhulin IB, Ordal GW.
  Title
CheC is related to the family of flagellar switch proteins and acts independently from CheD to control chemotaxis in Bacillus subtilis.
  Journal
Mol Microbiol 42:573-85 (2001)
DOI:10.1046/j.1365-2958.2001.02581.x
Reference
  Authors
Szurmant H, Bunn MW, Cannistraro VJ, Ordal GW.
  Title
Bacillus subtilis hydrolyzes CheY-P at the location of its action, the flagellar switch.
  Journal
J Biol Chem 278:48611-6 (2003)
DOI:10.1074/jbc.M306180200
Reference
  Authors
Szurmant H, Muff TJ, Ordal GW.
  Title
Bacillus subtilis CheC and FliY are members of a novel class of CheY-P-hydrolyzing proteins in the chemotactic signal transduction cascade.
  Journal
J Biol Chem 279:21787-92 (2004)
DOI:10.1074/jbc.M311497200
Reference
  Authors
Yoshihara S, Geng X, Okamoto S, Yura K, Murata T, Go M, Ohmori M, Ikeuchi M.
  Title
Mutational analysis of genes involved in pilus structure, motility and transformation competency in the unicellular motile cyanobacterium Synechocystis sp. PCC 6803.
  Journal
Plant Cell Physiol 42:63-73 (2001)
DOI:10.1093/pcp/pce007
Reference
PMID:8104179
  Authors
Darzins A.
  Title
The pilG gene product, required for Pseudomonas aeruginosa pilus production and twitching motility, is homologous to the enteric, single-domain response regulator CheY.
  Journal
J Bacteriol 175:5934-44 (1993)
DOI:10.1128/JB.175.18.5934-5944.1993
Reference
  Authors
Szurmant H, Ordal GW
  Title
Diversity in chemotaxis mechanisms among the bacteria and archaea.
  Journal
Microbiol Mol Biol Rev 68:301-19 (2004)
DOI:10.1128/MMBR.68.2.301-319.2004
Reference
  Authors
Rao CV, Glekas GD, Ordal GW
  Title
The three adaptation systems of Bacillus subtilis chemotaxis.
  Journal
Trends Microbiol 16:480-7 (2008)
DOI:10.1016/j.tim.2008.07.003
Reference
  Authors
Muff TJ, Ordal GW
  Title
The diverse CheC-type phosphatases: chemotaxis and beyond.
  Journal
Mol Microbiol 70:1054-61 (2008)
DOI:10.1111/j.1365-2958.2008.06482.x
Reference
  Authors
Miller LD, Russell MH, Alexandre G
  Title
Diversity in bacterial chemotactic responses and niche adaptation.
  Journal
Adv Appl Microbiol 66:53-75 (2009)
DOI:10.1016/S0065-2164(08)00803-4
Related
pathway
cck02040  Flagellar assembly
KO pathway
ko02030   
LinkDB

DBGET integrated database retrieval system