KEGG   Camelus dromedarius (Arabian camel): 105104642
Entry
105104642         CDS       T04642                                 

Gene name
GRB2
Definition
(RefSeq) growth factor receptor-bound protein 2
  KO
K04364  growth factor receptor-bound protein 2
Organism
cdk  Camelus dromedarius (Arabian camel)
Pathway
cdk01521  EGFR tyrosine kinase inhibitor resistance
cdk01522  Endocrine resistance
cdk04010  MAPK signaling pathway
cdk04012  ErbB signaling pathway
cdk04014  Ras signaling pathway
cdk04062  Chemokine signaling pathway
cdk04068  FoxO signaling pathway
cdk04072  Phospholipase D signaling pathway
cdk04150  mTOR signaling pathway
cdk04151  PI3K-Akt signaling pathway
cdk04380  Osteoclast differentiation
cdk04510  Focal adhesion
cdk04540  Gap junction
cdk04550  Signaling pathways regulating pluripotency of stem cells
cdk04630  JAK-STAT signaling pathway
cdk04650  Natural killer cell mediated cytotoxicity
cdk04660  T cell receptor signaling pathway
cdk04662  B cell receptor signaling pathway
cdk04664  Fc epsilon RI signaling pathway
cdk04714  Thermogenesis
cdk04722  Neurotrophin signaling pathway
cdk04910  Insulin signaling pathway
cdk04912  GnRH signaling pathway
cdk04915  Estrogen signaling pathway
cdk04917  Prolactin signaling pathway
cdk04926  Relaxin signaling pathway
cdk04935  Growth hormone synthesis, secretion and action
cdk05034  Alcoholism
cdk05160  Hepatitis C
cdk05161  Hepatitis B
cdk05163  Human cytomegalovirus infection
cdk05165  Human papillomavirus infection
cdk05200  Pathways in cancer
cdk05203  Viral carcinogenesis
cdk05205  Proteoglycans in cancer
cdk05206  MicroRNAs in cancer
cdk05210  Colorectal cancer
cdk05211  Renal cell carcinoma
cdk05213  Endometrial cancer
cdk05214  Glioma
cdk05215  Prostate cancer
cdk05220  Chronic myeloid leukemia
cdk05221  Acute myeloid leukemia
cdk05223  Non-small cell lung cancer
cdk05224  Breast cancer
cdk05225  Hepatocellular carcinoma
cdk05226  Gastric cancer
cdk05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:cdk00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    105104642 (GRB2)
   04012 ErbB signaling pathway
    105104642 (GRB2)
   04014 Ras signaling pathway
    105104642 (GRB2)
   04630 JAK-STAT signaling pathway
    105104642 (GRB2)
   04068 FoxO signaling pathway
    105104642 (GRB2)
   04072 Phospholipase D signaling pathway
    105104642 (GRB2)
   04151 PI3K-Akt signaling pathway
    105104642 (GRB2)
   04150 mTOR signaling pathway
    105104642 (GRB2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    105104642 (GRB2)
   04540 Gap junction
    105104642 (GRB2)
   04550 Signaling pathways regulating pluripotency of stem cells
    105104642 (GRB2)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    105104642 (GRB2)
   04660 T cell receptor signaling pathway
    105104642 (GRB2)
   04662 B cell receptor signaling pathway
    105104642 (GRB2)
   04664 Fc epsilon RI signaling pathway
    105104642 (GRB2)
   04062 Chemokine signaling pathway
    105104642 (GRB2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    105104642 (GRB2)
   04912 GnRH signaling pathway
    105104642 (GRB2)
   04915 Estrogen signaling pathway
    105104642 (GRB2)
   04917 Prolactin signaling pathway
    105104642 (GRB2)
   04926 Relaxin signaling pathway
    105104642 (GRB2)
   04935 Growth hormone synthesis, secretion and action
    105104642 (GRB2)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    105104642 (GRB2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    105104642 (GRB2)
  09159 Environmental adaptation
   04714 Thermogenesis
    105104642 (GRB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    105104642 (GRB2)
   05206 MicroRNAs in cancer
    105104642 (GRB2)
   05205 Proteoglycans in cancer
    105104642 (GRB2)
   05203 Viral carcinogenesis
    105104642 (GRB2)
   05231 Choline metabolism in cancer
    105104642 (GRB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    105104642 (GRB2)
   05225 Hepatocellular carcinoma
    105104642 (GRB2)
   05226 Gastric cancer
    105104642 (GRB2)
   05214 Glioma
    105104642 (GRB2)
   05221 Acute myeloid leukemia
    105104642 (GRB2)
   05220 Chronic myeloid leukemia
    105104642 (GRB2)
   05211 Renal cell carcinoma
    105104642 (GRB2)
   05215 Prostate cancer
    105104642 (GRB2)
   05213 Endometrial cancer
    105104642 (GRB2)
   05224 Breast cancer
    105104642 (GRB2)
   05223 Non-small cell lung cancer
    105104642 (GRB2)
  09165 Substance dependence
   05034 Alcoholism
    105104642 (GRB2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    105104642 (GRB2)
   05160 Hepatitis C
    105104642 (GRB2)
   05163 Human cytomegalovirus infection
    105104642 (GRB2)
   05165 Human papillomavirus infection
    105104642 (GRB2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    105104642 (GRB2)
   01522 Endocrine resistance
    105104642 (GRB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:cdk04131]
    105104642 (GRB2)
  09183 Protein families: signaling and cellular processes
   04990 Domain-containing proteins not elsewhere classified [BR:cdk04990]
    105104642 (GRB2)
Membrane trafficking [BR:cdk04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Receptor tyrosine kinase (RTK) adaptor proteins
    105104642 (GRB2)
Domain-containing proteins not elsewhere classified [BR:cdk04990]
 Src homology (SH) domain-containing proteins
  Signal transducing adaptor proteins
   105104642 (GRB2)
SSDB
Motif
Pfam: SH3_1 SH3_9 SH3_2 SH2 SH3_10 SH2_2 SH3_3 DUF5093 hSH3 SH3_4
Other DBs
NCBI-GeneID: 105104642
NCBI-ProteinID: XP_010996693
LinkDB
Position
16
AA seq 217 aa
MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPW
FFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFL
WVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRG
DFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV
NT seq 654 nt   +upstreamnt  +downstreamnt
atggaagccatcgccaaatatgacttcaaagctaccgcagacgacgagctgagcttcaaa
aggggggacatcctcaaggttttgaatgaagaatgtgaccagaactggtacaaggcagag
ctcaatgggaaagacggcttcatccccaagaattacatagaaatgaaaccacatccgtgg
ttttttggcaaaatccccagagccaaggcagaagaaatgcttagcaaacagcggcacgat
ggggcttttctgatccgagagagtgagagtgcgcctggggatttctccctctctgtcaag
tttggaaatgacgtgcagcacttcaaggtgctccgagacggagctggaaagtatttcctc
tgggtggtgaagttcaattctttgaatgagctggtagattatcacagatctacatccgtc
tctagaaaccagcagattttcctccgggacatagagcaggtgccacagcagccaacatac
gtccaagccctctttgacttcgatccccaggaggatggagagctgggattccgccgggga
gactttatccacgtcatggataactcagaccccaactggtggaaaggggcttgccacggg
cagaccggcatgtttccgcgcaattacgtcacccccgtgaaccggaacgtctaa

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