Canis lupus familiaris (dog): 100685468
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Entry
100685468 CDS
T01007
Symbol
ACACB
Name
(RefSeq) acetyl-CoA carboxylase 2 isoform X1
KO
K01946
acetyl-CoA carboxylase / biotin carboxylase 2 [EC:
6.4.1.2
6.3.4.14
2.1.3.15
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa00061
Fatty acid biosynthesis
cfa00620
Pyruvate metabolism
cfa00640
Propanoate metabolism
cfa01100
Metabolic pathways
cfa04152
AMPK signaling pathway
cfa04910
Insulin signaling pathway
cfa04920
Adipocytokine signaling pathway
cfa04922
Glucagon signaling pathway
cfa04931
Insulin resistance
cfa04936
Alcoholic liver disease
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
100685468 (ACACB)
00640 Propanoate metabolism
100685468 (ACACB)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
100685468 (ACACB)
09110 Biosynthesis of other secondary metabolites
00254 Aflatoxin biosynthesis
100685468 (ACACB)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
100685468 (ACACB)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
100685468 (ACACB)
04922 Glucagon signaling pathway
100685468 (ACACB)
04920 Adipocytokine signaling pathway
100685468 (ACACB)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
100685468 (ACACB)
04931 Insulin resistance
100685468 (ACACB)
Enzymes [BR:
cfa01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
100685468 (ACACB)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
100685468 (ACACB)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
100685468 (ACACB)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ACC_central
Carboxyl_trans
CPSase_L_D2
ACCA_BT
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
Dala_Dala_lig_C
ATP-grasp_3
Motif
Other DBs
NCBI-GeneID:
100685468
NCBI-ProteinID:
XP_005636385
Ensembl:
ENSCAFG00000010991
VGNC:
37490
LinkDB
All DBs
Position
26:17906250..18037960
Genome browser
AA seq
2431 aa
AA seq
DB search
MTDSKQVTKNKSEGSCIPSQEPFPASDSSGGPPKKNGNSSPLPETPNQAESVSHKDPQDA
CEQRNSRPPPHQNLPGNPCSSDDTPAALQANETGTKGLKIPDTNGLSSPAKPQGQQARPL
SKEDEKQEHIKRQLMTNFILGSFDDNSSDEDPGAGWFWESSRKGSRASLGALSLEAAPTI
GEPEHPGLAIRPSMSGLHLVKRGRELKKLDLHRDFTVASPAEFVVRFGGDRVIEKVLIAN
NGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADQYVPVPGGPNNN
NYANVELVVDIAKRIPVQAVWAGWGHASENPKLPELLSKHEIAFLGPPSEAMWALGDKIA
STIVAQTLQIPTLPWSGSGLMVEWSEDDLQEGKRITVPEDIYNQGCVKDIDEGLEVAEKI
GFPLMIKASEGGGGKGIRKAESAEDFPILFRQVQSEIPGSPVFLMKLAEHARHLEVQILA
DQYGNAVSLFGRDCSIQRRHQKIIEEAPATIAIPAVFEFMEQCAVCLAKTVGYVSAGTVE
YLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPLHRLKDIRLLYGESP
WGVTPISFDTPANPPLARGHVIAARITSENPDEGFKPSSGTVQELNFRSSKNVWGYFSVA
AAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLINLLETASFQ
NNDIDTGWLDHLIAEKVQAEKPDIMLGVVCGALNVADAMFRTCMTDFLHSLERGQVLPAA
SLLNIVDVELIYGGVKYILKVARQSLTMFILIMNDSHIEIDAHRLSDGGLLLSYNGNSYT
TYMKEEFDSYRITIGNKTCVFEKENDPTVLRAPSAGKLMQYTVEDGGHVEAGSSYADMEV
MKMIMTLNVQESGQVKYIKRPGAMLEAGCVVARLELDDPSKVHPAKPFTGELPSQQTLPI
MGEKLHQVFHNVLENLTNVMSGYCLPEPIFSKKLKEWVQKLMTTLRHPSLPLLELQEIMT
SVSGRIPAPVEKSVRRVMAQYASNITSVLCQFPSQQIATILDCHAATLQRKADREVFFMN
TQSIVQLVQRYRSGIRGYMKVVVLDLLRRYLRVEHHFQQAHYDKCVINLREQLKPDMSQV
LDCIFSHAQVAKKNQLVIMLIDELCGPDPSLSEELTSILNELTQLSKSEHCKVALRARQV
LIASHLPSYELRHNQVESIFLSAIDMYGHQFCPENLKKLILSETTIFDVLPTFFYHTNKV
VCMASLEVYVRRGYIAYELNSLQHRQLPDGTCVVEFQFMLPSSHPNRMAVPISITNPDLL
RHSTELFMDSGFSPLCQRMGAMVAFRRFEDFTRNFDEVISCFANVPREAPLFSKACTSLY
SEEDSKNLREEPIHILNVALQYADHLEDELLVPIFRTFVQSKKNILVDYGLRRITFLIAQ
EKEFPKFFTFRARDEFAEDRIYRHLEPALAFQLELSRMRNFDLTAVPCANHKMHLYLGAA
KVQEGAEVTDHRFFIRAIIRHSDLVTKEASFEYLQNEGERLLLEAMDELEVAFNNTTVRT
DCNHIFLNFVPTVIMDPLKIEESVRSMVMRYGSRLWKLRVLQAEVKINIRQTTTGRAVPI
RLFITNESGYYLDISLYKEVTDPRSGNIMFHSFGNKQGPQHGMLINTPYVTKDLLQAKRF
QAQSLGTTYVYDFPEMFRQALFKLWGTPDKYPKDILTYTELVLDPQGQLVEMNRLPGGNE
VGMVAFKMRFKTPEYPEGRNVIVISNDITFRIGSFGMGEDLLYLRASEMARAEGIPKIYL
AANSGACIGLAEEIKHIFQVAWVDPGDPHKGFKYLYLTPKDYTTISSLNSVHCKHIEEDG
ESRYVITDIIGKDSGVGVENLRGSGMIAGESSLAYEEIVTISLVTCRAVGIGAYLVRLGQ
RVIQVENSHIILTGATALNKVLGREVYTSNNQLGGVQIMHYNGVSHITVPDDFEGVYTIL
DWLSYMPKDNHSPVPIITPTDPIDREVGFFPTKTPYDPRWLLAGRPHPTLKGSWQSGFFD
YGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVETRTVEVVVPADPANLDSEAKIIQQAGQ
VWLPDSAYKTAQAIKDFNRERLPLIIFANWRGFSGGMKDMYDQMLKFGAYIVDSLRQYKQ
PVLIYIPPYAELRGGSWVVVDSSINPLCIETYADKESRANILEPEGTVEIKYRKKDLIKT
MRRIDPVCKKLMEGLGMSELSDKDRKDLEGQLKAREDLLLPIYHQVAVQFASLHDKPICM
LEKGAIFDILEWKTARTFLYWRLRRLLLEDQVKQEILQVSSELSHVHVQSMLRRWFVETE
GAVKAYLWDNNQMVVQWLEQHWQTGNSLRSTIHENIRCLKRDSVLKAIRRLVQDNPEVAV
DCIVYMSQHISPAERAQVIHLLSTMDSPAST
NT seq
7296 nt
NT seq
+upstream
nt +downstream
nt
atgacagactctaagcaagtcaccaagaataaatcagaagggagctgtatcccaagccag
gagccttttccagcctcagacagctcaggggggccaccaaagaagaatggtaacagcagc
cctctgccagagactcctaaccaggctgaatcagtctcccacaaagatccccaagatgct
tgtgagcaaagaaattccaggccacctccacaccagaatctcccaggaaacccctgttcc
tctgatgacacccctgcagcactccaagccaatgagacagggaccaaaggcctgaagatc
ccagatactaatggcctgtcatctccagccaagccccaaggccagcaagccagacccctc
tccaaagaagacgagaagcaggagcacatcaagaggcagctgatgaccaacttcatcctg
ggctcctttgatgacaactcctccgatgaggaccctggtgctggctggttctgggagtct
tcccggaagggcagccgggccagcctgggtgccctttccctggaggctgctccaaccata
ggcgagcctgagcaccccggccttgctataagacccagcatgtcaggactccacctggtg
aagcgcggccgagaactgaagaagctggacctgcacagagactttaccgtggcctcccca
gctgagtttgtcgtgcgctttgggggggaccgggtcattgagaaggtgctcatcgccaac
aatggcatcgctgccgtgaagtgcatgcgctccatccgcaggtgggcctatgagatgttc
cgcaacgagcgggccatccggtttgtagtcatggtgaccccagaggacctgaaggccaat
gcagagtatatcaagatggcagatcagtatgttcctgtcccaggagggcccaacaataac
aattatgccaatgtggaactggttgtggacattgccaagagaatcccggtgcaggcggtg
tgggctggctggggccatgcttctgaaaaccccaaactgccggagctcctgtccaagcat
gagattgctttcttaggccctcccagtgaggccatgtgggccttgggagataagattgcc
tccaccatcgtggcccagacactgcaaatcccaacactgccctggagtggaagtggtctg
atggtagaatggtcagaagatgatctgcaggaggggaaaagaatcactgtcccagaagat
atttacaaccagggctgtgtgaaagatatagatgaaggcttagaggtggctgaaaaaatt
ggttttcccttgatgatcaaagcatctgaaggtggcggagggaaaggaatccggaaggca
gagagtgctgaggacttcccaatccttttcagacaagtgcagagtgagatccccggctcc
cccgtctttctcatgaagctggccgagcacgcccgacacctggaggtccagattcttgct
gaccaatatgggaacgctgtgtctctgttcggccgtgactgctccatccagcgccggcat
cagaagatcatcgaggaggcgccggccaccatcgccataccggctgtgttcgagttcatg
gagcagtgtgctgtctgcctggccaagactgtgggctacgtgagcgcagggacggtggag
tatctctacagccaggacggcagctttcacttcttggagctgaatccccgcctgcaggtg
gaacatccctgcacggaaatgattgctgatgtcaacctgccggccgcccagctacagatt
gccatgggagtgccactgcaccggctgaaagatatccggcttctgtacggagagtcgcca
tggggggtgacacccatttcatttgacactcctgccaatcctccgctcgcccgaggccat
gtcatcgcagccagaatcaccagtgagaaccctgatgaggggtttaagccaagctctgga
acagttcaggaactgaatttccggagcagcaagaatgtgtggggttatttcagcgtggca
gctgctggcggcttacacgaatttgctgattcccagttcggtcactgcttctcctgggga
gagaaccgggaagaggccatttcgaacatggtggtggctttgaaggaactgtccatccgg
ggtgacttcaggaccaccgtggagtatctcattaacctgctggagactgcaagcttccag
aacaatgatatcgacacagggtggttggatcacctcattgctgagaaagtgcaggctgag
aagccggatatcatgctcggggtggtgtgcggagccttgaatgtggccgacgcaatgttc
agaacctgcatgacggatttcttacactcgctggaaaggggccaagtccttcctgcagct
tctctgcttaacatcgtggacgtggaattaatttatggaggtgttaagtacattctcaag
gtggcccgacaatctctgaccatgttcatcctcatcatgaatgacagtcacattgagatc
gacgcccaccggctgagtgacggtggcttgctgctgtcctataatggtaacagctatacc
acctacatgaaagaagagtttgacagttatcgtattaccatcggcaacaagacctgtgtg
tttgagaaggagaacgatcctacggttctgagagccccttcggccgggaagctaatgcag
tacacggtggaggacgggggccacgttgaggctgggagcagctacgctgacatggaggtg
atgaagatgatcatgactctgaacgtgcaggaaagtggccaggtgaagtacatcaagcgc
cctggggccatgctggaagcaggctgtgtggtggccaggctggagctcgatgacccttct
aaagtgcacccggccaagccattcacaggcgagctcccttctcagcaaactctgcctatc
atgggagagaaactgcaccaggttttccacaacgtcctggaaaacctgaccaacgtcatg
agtggctactgtctgccggagcctatttttagcaaaaagctgaaggagtgggtgcagaag
ctcatgacgaccctccggcatccatcactgccactgctggagctgcaggaaatcatgacc
agtgtgtctggccgcatccctgcccctgtggagaagtcggtccgcagggtgatggctcag
tacgccagcaacatcacctcagtgctgtgccagttccccagccagcagatagccaccatc
ctggactgccacgcagccaccctacagcggaaggctgaccgggaggtcttcttcatgaac
acccagagcatcgtgcagctggtccagaggtaccgcagcgggatccgtggctacatgaag
gtggtggtgttggacctcctgagaagatacttacgcgtggaacaccatttccaacaagct
cactatgacaagtgtgtgataaacctcagggagcagctgaagccagacatgtctcaggtg
ctggattgcatcttttcccatgcacaggtggccaagaagaaccagctggtgatcatgttg
attgatgagctctgtggcccagacccttccctgtctgaagagctgacctccatcctcaac
gagctcactcagctgagcaaaagcgagcattgcaaggtggccctcagagccagacaggtc
ctgattgcctcccacctcccgtcctatgagctgaggcacaaccaggtagagtccattttc
ctgtctgccatcgacatgtacggccaccagttctgcccagaaaacctcaagaaattaata
ctctcagaaacgaccatatttgacgtcctgcccactttcttctaccacaccaacaaagtt
gtctgtatggcatctttggaggtttatgtgcggaggggctacattgcctatgagttaaac
agcttgcagcaccgacagctcccggacggcacctgtgtggtggaattccagttcatgctg
ccctcttcccacccaaacaggatggctgtgcccatcagcatcaccaaccccgacctgctc
aggcacagcaccgagctcttcatggacagcggcttctccccactgtgccagcggatgggg
gccatggtcgccttcaggagatttgaggacttcacaaggaactttgacgaagtcatctcc
tgctttgccaatgtgcccagggaagctcccctcttcagcaaggcctgtacttccctgtac
tctgaagaagacagcaagaacctccgagaagagcccattcacatcctcaatgtggccctc
cagtacgcggatcacctggaagacgagctgctggttccaattttccggacatttgtgcag
tccaagaaaaacatccttgtggattatggactccgaagaatcacattcctgattgctcaa
gagaaagaatttcccaagtttttcacattcagagcaagagacgagtttgccgaagatcgc
atttaccgacacctggagcctgccctggctttccagctggagctcagccggatgcgcaac
tttgatctgactgctgtgccctgtgccaaccacaagatgcacctttacctgggcgctgcc
aaagtgcaagaaggtgcagaagtgacagaccacaggttctttatccgcgccatcatcagg
cactcagaccttgttacaaaggaagcttccttcgagtacttgcagaacgagggtgagcgt
ctgctcctggaagccatggatgagctggaagtggcgttcaacaacactaccgtgcgtaca
gactgcaaccacatcttcctgaacttcgtgcccaccgtcatcatggaccctcttaagatt
gaagagtccgtgcgttccatggttatgcgctatggcagccggctgtggaaactccgcgtg
ctgcaggctgaggtcaagatcaacatccgccagaccaccactggcagggctgttcccatc
cgcctgttcatcaccaatgagtcgggctactacctggacatcagcctctacaaggaagtc
actgaccccagatctggaaatatcatgtttcattcctttggcaataaacagggaccccag
catgggatgctgatcaacactccctatgtcaccaaggatctgcttcaggccaagcgattc
caggcccagtccctgggcaccacctatgtctacgacttccccgagatgttcaggcaggct
ctctttaaattgtggggcaccccggacaaataccccaaagacatcctgacctacacagag
ctggtgctggaccctcagggtcagctagtggagatgaaccgtctccctggagggaatgag
gtgggcatggtggccttcaaaatgagattcaagaccccagagtatccagaagggcggaac
gtgatcgtcatcagcaatgacatcacattccgcattggatcctttggcatgggagaagac
ctcctgtacttgcgggcgtcggagatggcccgggcagagggtatccccaaaatctacctt
gcagccaacagtggggcctgtattggccttgcagaggagatcaagcacatattccaagtg
gcttgggtggacccaggagacccccacaaaggatttaaatacttgtacctgacccccaaa
gactacaccacaatcagctccctgaactctgtccattgtaaacacatcgaggaagatgga
gaatccaggtatgtcatcacggatatcatcgggaaggacagtggtgtgggcgtggagaat
ctcaggggctctggtatgattgcgggggagtcctccctggcttacgaagaaattgtcacc
atcagcttggtgacctgccgagctgtggggattggggcctacttggtgaggctgggccag
cgagtgatccaggtggaaaattctcacatcatcctgacaggagcaactgctctcaacaag
gtcctgggcagagaggtttacacctccaacaaccagctgggcggcgtgcagatcatgcat
tacaatggtgtctcccacatcaccgtgccagatgacttcgagggcgtttataccatcctg
gactggctgtcctacatgccgaaggataatcacagcccagtccccatcatcacgcccacg
gaccccattgacagagaagttggattcttcccaaccaagactccctatgacccccggtgg
ctgcttgcaggaaggcctcacccaactctgaagggatcctggcagagtggattctttgac
tatggcagtttcaaggaaatcatggcaccttgggcccagactgtggtgacaggacgagca
aggctaggggggatccctgttggagtgatcgccgtggagacgcggaccgtggaggtggtg
gtgcctgcggaccctgccaatctggattcagaggcgaagataatccagcaggcaggccag
gtgtggctcccagactcggcctataagacagcccaggccatcaaggatttcaaccgagag
aggttgcccctgattatctttgccaactggagagggttctctggtggcatgaaagacatg
tatgaccagatgctgaagtttggagcctacattgtagacagtctcagacagtacaaacag
cccgtcctgatctacatcccaccctatgcagagctccgggggggctcctgggtggtcgtg
gactcctccatcaaccccttgtgcatagaaacgtatgcagacaaggagagcagggcaaat
attctggagccagagggcacagtggagattaagtaccgaaagaaagatctgataaagact
atgagaaggatcgacccagtttgcaagaaactcatggaagggctaggaatgtctgagctc
tccgacaaggatcgcaaggacctggagggccagctgaaggccagggaggacctgctgctg
cccatctaccaccaggtggcggtgcagttcgccagcctccatgacaagcccatctgcatg
ctggagaagggtgccatctttgacatcctggagtggaagactgcacgcaccttcctgtac
tggcgtctgcgccgcctcctgctggaggaccaggtcaagcaggaaatcctgcaggtcagc
agtgagctgagccacgtgcacgtccagtccatgctgcgccggtggtttgtggagacggag
ggggccgtcaaggcctacctgtgggacaacaaccagatggtggtacagtggctggaacaa
cactggcagacggggaacagcctgcgttccaccatccatgagaacatcaggtgcttgaag
cgagactctgtcctcaaggccatcagacgcctggttcaagacaatcctgaagtggccgtg
gactgcatagtgtacatgagccagcacatcagcccagccgagcgagctcaagtcattcac
ctcctgtctaccatggacagtcccgcctccacctga
DBGET
integrated database retrieval system
