KEGG   Canis familiaris (dog): 477813Help
Entry
477813            CDS       T01007                                 

Gene name
GSTO1
Definition
(RefSeq) glutathione S-transferase omega-1
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
cfa  Canis familiaris (dog)
Pathway
cfa00480  Glutathione metabolism
cfa00980  Metabolism of xenobiotics by cytochrome P450
cfa00982  Drug metabolism - cytochrome P450
cfa00983  Drug metabolism - other enzymes
cfa01100  Metabolic pathways
cfa01524  Platinum drug resistance
cfa05200  Pathways in cancer
cfa05204  Chemical carcinogenesis
cfa05225  Hepatocellular carcinoma
cfa05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    477813 (GSTO1)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    477813 (GSTO1)
   00982 Drug metabolism - cytochrome P450
    477813 (GSTO1)
   00983 Drug metabolism - other enzymes
    477813 (GSTO1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    477813 (GSTO1)
   05204 Chemical carcinogenesis
    477813 (GSTO1)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    477813 (GSTO1)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    477813 (GSTO1)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    477813 (GSTO1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:cfa02000]
    477813 (GSTO1)
Enzymes [BR:cfa01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     477813 (GSTO1)
Transporters [BR:cfa02000]
 Other transporters
  Pores ion channels [TC:1]
   477813 (GSTO1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: GST_N_3 GST_N_2 GST_N GST_C_3 GST_C GST_C_2 Glutaredoxin GST_C_5
Motif
Other DBs
NCBI-GeneID: 477813
NCBI-ProteinID: XP_535007
Ensembl: ENSCAFG00000010593
VGNC: 41536
UniProt: F1PUM3
LinkDB All DBs
Position
28
AA seq 241 aa AA seqDB search
MSAGSARSLAKGSAPPGPVPEGLIRVYSMRFCPFAQRTLLVLKAKGIRHEIININLKNKP
EWFFKKNPFGLVPVLENSQGQLIYESPITCEYLDEAYPGKKLLPDDPYEKACQKMVFELF
SKVPSLVTGFLRRQNKEDGSGLKEELRKEFSKLEEVLTNKKTTFFGGNSLSMIDYLIWPW
FERLEALELNDCVDHTPKLKLWMAAMREDPAVSALLNEANTLRGFLNLYLQNSPEACDYG
L
NT seq 726 nt NT seq  +upstreamnt  +downstreamnt
atgtccgcagggtcagccaggagcctggcgaagggaagcgcgcccccggggccggtcccc
gagggcctcatccgcgtctacagcatgaggttttgcccgttcgcccagaggacactcttg
gtcctgaaggccaaggggatcaggcatgaaatcatcaacatcaacctgaaaaataagcct
gagtggttctttaagaagaatccctttggcctagtgccagttctggaaaacagtcagggt
caattgatctatgaatctcctatcacttgtgagtatctggatgaagcatatccagggaag
aagctgttgccggatgatccctatgagaaagcttgccaaaagatggtgtttgagttattt
tccaaggttccatctttggtaacaggctttctgagaagacaaaataaggaagatggctct
ggcctaaaagaagaattacggaaggaattcagcaagctagaggaggttctgaccaataag
aagacaactttctttggtggtaattctctttctatgattgattacctcatctggccctgg
tttgaacggctggaagctctggagttaaatgattgtgtagaccacactccaaaacttaag
ctctggatggcagccatgagagaagatcctgccgtatcagccctcctcaatgaggccaac
acccttcgaggattcctcaatctctacttgcagaacagccccgaggcctgtgactatggg
ctctga

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