KEGG   Canis familiaris (dog): 478794Help
Entry
478794            CDS       T01007                                 

Gene name
GAD1
Definition
(RefSeq) glutamate decarboxylase 1
  KO
K01580  glutamate decarboxylase [EC:4.1.1.15]
Organism
cfa  Canis familiaris (dog)
Pathway
cfa00250  Alanine, aspartate and glutamate metabolism
cfa00410  beta-Alanine metabolism
cfa00430  Taurine and hypotaurine metabolism
cfa00650  Butanoate metabolism
cfa01100  Metabolic pathways
cfa04727  GABAergic synapse
cfa04940  Type I diabetes mellitus
Module
cfa_M00027  GABA (gamma-Aminobutyrate) shunt
Brite
KEGG Orthology (KO) [BR:cfa00001]
 Metabolism
  Carbohydrate metabolism
   00650 Butanoate metabolism
    478794 (GAD1)
  Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    478794 (GAD1)
  Metabolism of other amino acids
   00410 beta-Alanine metabolism
    478794 (GAD1)
   00430 Taurine and hypotaurine metabolism
    478794 (GAD1)
 Organismal Systems
  Nervous system
   04727 GABAergic synapse
    478794 (GAD1)
 Human Diseases
  Endocrine and metabolic diseases
   04940 Type I diabetes mellitus
    478794 (GAD1)
Enzymes [BR:cfa01000]
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.1  Carboxy-lyases
    4.1.1.15  glutamate decarboxylase
     478794 (GAD1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Pyridoxal_deC Aminotran_5 Beta_elim_lyase SepSecS DegT_DnrJ_EryC1 OKR_DC_1
Motif
Other DBs
NCBI-GeneID: 478794
NCBI-ProteinID: NP_001091012
Ensembl: ENSCAFG00000012560
VGNC: 41067
UniProt: A0PA85
LinkDB All DBs
Position
36
AA seq 594 aa AA seqDB search
MASSTPSSSATSSNAGADPNTANLRPTTYDTWCGVAHGCTRKLGLKICGFLQRTNSLEEK
SRLVSAFKERQSSKNLLSCENSDRDGRFRRTETDFSNLFARDLLPAKNGEEQTVQFLLEV
VDILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDHPESLEQILVDCRDTLKYGV
RTGHPRFFNQLSTGLDIIGLAGEWLTSTANTNMFTYEIAPVFVLMEQITLKKMREIVGWS
SKDGDGIFSPGGAISNMYSIMAARYKFFPEVKTKGMAAVPKLVLFTSEHSHYSIKKAGAA
LGFGTDNVILIKCNERGKIIPADLEAKILEAKQKGYVPLYVNATAGTTVYGAFDPIQEIA
DICEKYNLWLHVDAAWGGGLLMSRKHRHKLSGIERANSVTWNPHKMMGVLLQCSAILVKE
KGILQGCNQMCAGYLFQPDKQYDVSYDTGDKAIQCGRHVDIFKFWLMWKAKGTVGFENQI
NKCLELAEYLYAKIKNREEFEMVFDGEPEHTNVCFWYIPQSLRGIPDSPERREKLHRVAP
KIKALMMESGTTMVGYQPQGDKANFFRMVISNPAATQSDIDFLIEEIERLGQDL
NT seq 1785 nt NT seq  +upstreamnt  +downstreamnt
atggcgtcttcgaccccttcttcgtccgcaacctcctcgaatgcgggagcggaccccaat
actgccaacctgcgccccacaacgtatgacacctggtgcggcgtggcccatggatgcacg
agaaaactgggtctcaagatctgcggcttcttgcaaaggaccaacagcctggaagagaag
agccggcttgtgagcgccttcaaggagaggcagtcctccaagaacctgctttcctgtgaa
aacagtgacagggatggccgtttccggcgcacagagactgatttctccaacctctttgct
cgagatctgcttccagctaagaatggggaggagcaaacagtgcagttcctcctggaagtg
gtagacatactcctcaactatgtccgcaagacatttgatcgctccaccaaggtactggac
ttccatcacccgcaccagctgctggaaggcatggagggcttcaacttggagctgtctgac
caccccgagtccctggagcagatcttggttgactgcagagacaccctgaagtatggggtc
cgtacaggtcatcctcgatttttcaaccagctctccactggattggatatcattggttta
gctggcgaatggctgacatcaactgccaataccaatatgtttacatatgaaattgcacca
gtatttgtcctcatggagcaaataacacttaagaagatgagagagatagttggatggtca
agtaaagatggtgatgggatattttctcctgggggagccatctccaacatgtacagcatc
atggctgctcgctacaagttcttcccggaagttaagacaaagggcatggcggccgttccc
aaactggtcctcttcacctcagaacacagtcactattccataaagaaggctggagctgca
cttggctttggaactgacaatgtgattttgataaagtgcaacgaaagggggaagataatt
ccagctgacttagaagcaaaaattcttgaagccaagcaaaagggatatgttcctctttac
gtcaatgcaactgctggcacgactgtgtatggggcttttgatccgatacaggagattgca
gatatatgtgagaaatataacctatggctgcatgtcgatgctgcctggggcggtgggctg
ctcatgtcccggaagcaccgccacaaactcagcggcatagaaagggccaactcagtcacc
tggaaccctcacaagatgatgggcgtgctgttgcagtgctctgccattcttgtcaaggaa
aagggtatactccaaggatgcaaccagatgtgtgcaggataccttttccagccagacaag
cagtacgacgtctcttatgacactggggacaaggcaatccagtgtggtcgccacgtggac
attttcaagttctggctgatgtggaaagcaaagggcacagtgggatttgaaaatcagatc
aacaaatgcttggaattggccgaatacctctatgccaagattaaaaacagagaagaattt
gagatggttttcgacggtgagcctgagcatacaaacgtctgtttctggtatattccacaa
agcctcaggggcattccagatagccctgaacgacgggaaaaactacacagggtggctccc
aaaatcaaagccctgatgatggagtctggcacaacgatggttggctaccagcctcagggg
gacaaggccaactttttccggatggtcatctcgaacccagctgctacacagtctgatatt
gacttcctcattgaggagatagaaagactgggccaggatctgtaa

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