Canis lupus familiaris (dog): 479540
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Entry
479540 CDS
T01007
Symbol
PDE4B
Name
(RefSeq) cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1
KO
K13293
cAMP-specific phosphodiesterase 4 [EC:
3.1.4.53
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa00230
Purine metabolism
cfa01100
Metabolic pathways
cfa04024
cAMP signaling pathway
cfa04928
Parathyroid hormone synthesis, secretion and action
cfa05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
479540 (PDE4B)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
479540 (PDE4B)
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
479540 (PDE4B)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
479540 (PDE4B)
Enzymes [BR:
cfa01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
479540 (PDE4B)
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Gene cluster
GFIT
Motif
Pfam:
PDEase_I
PDE4_UCR
Motif
Other DBs
NCBI-GeneID:
479540
NCBI-ProteinID:
XP_003434692
Ensembl:
ENSCAFG00000018583
VGNC:
44354
UniProt:
A0A8C0QIS1
A0A8I3SBV2
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Position
5:complement(44186161..44663652)
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AA seq
737 aa
AA seq
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MKKSRSVMAVTADDNVKDYLECSLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLAQRQS
ERARTPEGDGISRPTTLPLMTLPSIAITTVSQECFDVENGPSPGRSPLDPQASSSSGLVL
HATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVR
NNFTVLTNLHGASNKRSPAATSQPPVSRVNLQEESYQKLAMETLEELDWCLDQLETIQTY
RSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKK
KKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYS
HNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAADVAQSTH
VLLSTPALDAVFTDLEILATIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHH
LAVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVT
SSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGME
ISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMIPQS
PSPPLDEQNRDCQGLMEKFQFELTLEEEDSEGPDKEGEGHNYFSSTKTLCVIDPEHRDSL
GDTDGDTGAENKTPIDT
NT seq
2214 nt
NT seq
+upstream
nt +downstream
nt
atgaagaaaagcaggagtgtgatggcagtgacagctgatgataatgttaaagattatttg
gaatgtagcttgagtaaatcctatagttcttctagtaacacacttgggattgacctctgg
agagggagaaggtgttgctcaggaaacttacagctaccgccactggcccaaagacagagt
gagagagcaaggactcctgagggagatggcatttccagacccactacgctgcctttgatg
acacttccaagcatcgctattacaaccgtaagccaggagtgctttgatgtggaaaatggc
ccttctccaggtcggagcccgctggacccccaggccagctcttcctctgggttggtgctc
catgccacctttcctgggcacagccagcgtagagagtcctttctctacagatcagacagc
gactatgacctgtcaccaaaggcaatgtcaagaaactcttcacttccaagcgagcaacat
ggcgatgacttgattgtcacaccttttgcccaggtccttgccagcttgcgaagtgtgaga
aacaactttactgtactgacaaaccttcatggagcatccaacaagagatccccagctgct
actagtcagccacctgtctccagagtcaacctgcaagaagaatcttatcaaaaattagca
atggaaacgctggaggaattggactggtgcctagaccagctcgagaccatccagacctac
cgctccgtcagtgagatggcttctaacaagttcaaaagaatgctgaaccgggaactgaca
cacctctcagagatgagccgatcaggaaaccaggtttctgaatacatttcaaatactttc
ttagataagcagaatgatgtggagattccatctcccacccagaaagaccgagagaaaaag
aaaaagcaacaactcatgacacagataagtggagtgaaaaaactaatgcatagctcaagc
ttgaacaatacaagcatttcacgctttggagtcaacacagaaaatgaagatcatctggcc
aaggagctggaagacctgaacaaatggggccttaacatcttcaatgtggctggatattca
cacaataggcccctcacatgcatcatgtatgccattttccaggaaagagacctcctaaag
acattcaaaatctcatctgatacatttgtaacctacatgatgactttagaagaccattac
cattctgatgtggcatatcataacagcctacacgctgctgatgtagcccagtcaacccat
gttcttctttctacgccagcattagatgctgtcttcactgatttggaaattctggccacc
atttttgcagctgctatccatgacgtggatcaccctggagtctccaaccagtttctcatc
aacacaaattcagaactcgctttgatgtataatgatgaatctgtgttggaaaaccatcac
cttgctgtgggtttcaagctgctgcaagaagaacactgtgacatcttccagaatctcacc
aagaagcagcgccagacactcaggaaaatggttattgacatggtgttagcaactgatatg
tccaaacatatgagcctgctggcagacctgaagacaatggtagaaacaaagaaagttaca
agttcaggtgttcttctcctggacaactacacggatcgtatacaggtccttcgcaacatg
gtacactgtgcagacctgagcaaccccaccaagtcgttggaattgtatcggcaatggaca
gaccgcatcatggaagaatttttccagcagggagacaaagagcgggagagaggaatggag
attagcccaatgtgtgataagcacacagcttctgtggaaaaatcccaggtcggtttcatt
gactacatcgttcacccactgtgggagacctgggcagatctggtacagcctgatgcccag
gacattctggatacattagaagataacaggaactggtatcagagcatgataccccagagt
ccctccccaccgctggatgagcagaacagagactgtcagggtctgatggagaagtttcag
tttgaactaacccttgaagaggaggattctgaaggccctgacaaagagggagagggtcac
aattatttcagcagcacaaagacactttgtgtgatcgaccctgaacatagggattcgcta
ggagacactgatggagacactggggcggagaacaagaccccgatcgacacataa
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