Canis lupus familiaris (dog): 482519
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Entry
482519 CDS
T01007
Symbol
PTCH2
Name
(RefSeq) protein patched homolog 2 isoform X1
KO
K11101
patched 2
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa04340
Hedgehog signaling pathway
cfa05200
Pathways in cancer
cfa05217
Basal cell carcinoma
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04340 Hedgehog signaling pathway
482519 (PTCH2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
482519 (PTCH2)
09162 Cancer: specific types
05217 Basal cell carcinoma
482519 (PTCH2)
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Gene cluster
GFIT
Motif
Pfam:
Patched
Sterol-sensing
Motif
Other DBs
NCBI-GeneID:
482519
NCBI-ProteinID:
XP_005629137
Ensembl:
ENSCAFG00000004694
VGNC:
45133
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Position
15:15608551..15623939
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AA seq
1233 aa
AA seq
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MARPPPLQELPPGYTPPARATSPQIPAGSLKAPLWLRAYFQGLLFSLGCGIQRHCGKVLF
LGLLAFGALALGLRVAIVETDLEQLWVEVGSRVSQELHYTKEKLGEEAAYTSQMLIQTPR
QEGENVLTPEALGLHLQAALTASKVQVSLYGKSWDLNKICYKSGIPLIENGMIERMIEKL
FPCVILTPLDCFWEGAKLQGGSAYLPGRPDIQWTNLDPEQLLEELGPFASLEGFRELLDK
AQVGQAYVGRPCLHPDDLHCPPSAPNHHSKQAPNVAQELSGGCHGFSHKFMHWQEELLLG
GMARDPQGQLLRAEALQSTFLLMSPRQLYEHFRGDYQTHDIGWSEEQAGTVLQAWQRRFV
QVSVRMGKGGARGCSLLLPLRSTLSLQLAQEALPQNSSQQIHAFSSTTLDDILHAFSEVS
AARVVGGYLLMLAYACVTMLRWDCAQSQGAVGLAGVLLVALAVASGLGLCALLGIAFNAA
TTQVLPFLALGIGVDDIFLLAHAFTEAPPGTPLQERTGECLQRTGTSVALTSISHMVAFF
MAALVPIPALRAFSLQAAIVVGCNFAAVMLVFPAVLSLDLHRRHCQRLDVLCCFSSPCSA
RVIQILPQELGDGTVPVGIAHLTATVQAFAHCEAGSQHVVTILPPRARLVPPPSDPLGSE
LFSPGGSTRDLLGQEEGTRQKATCSSLPCARWNLAHFARSQFAPLLLQSHSKAIVLVLFG
ALLGLSLYGATLVQDGLALTDVVPRGTKEHAFLSAQLRYFSLYEVALVTQGGFDYAHSQR
ALFDLHQRFSSLKAVLPTPATQAPRTWLHYYRNWLLGIQAAFDQDWASGRISRHSCRNGS
EDGALAYKLLLQTGDAQEPLDFSQLTTRKLVDKEGLIAPELFYVGLTMWVSSDPLGLAAS
QANFYPPPPEWLHDKYDTTGENLRIPAAQPLEFAQFPFLLRGLQKTADFVEAIEGARAAC
AEAGQAGVRAYPSGSPFLFWEQYLGLRRYFLLAICILLVCTFLVCALLLLNPWTAGLIVL
VLAMMTVELFGIMGFLGIKLSAIPVVILVASVGIGVEFTVHVALGFLTTQGSRNLRAAHA
LERTFAPVTDGAVSTLLGLLMLAGSNFDFIIRYFFVVLTVLTLLGLLHGLVLLPVLLSIL
GPPPEVVQMYKESPEVLSPPAPREGGLRWGLPPTLPQSFARVTTSMTVALHPPPLPGAYI
HPASDEPTWSPVATSAASGSSNLSSRGPCPATG
NT seq
3702 nt
NT seq
+upstream
nt +downstream
nt
atggcccggccgccgccgctccaggagctgccccctggctatacacccccagctcgagcc
acgtcgccccagatcccagccgggagcctgaaggctccactctggcttcgcgcttacttc
cagggcctgctcttctctctgggctgcgggatccagagacactgtggcaaagtgctcttc
ctgggcctcttggccttcggagccctggcactgggtcttcgcgtggccatcgttgagaca
gacctagaacagctctgggtggaagtgggcagccgggtgagccaggagttgcattacacc
aaggagaagctgggggaggaggctgcatacacctcccagatgctgatacagaccccacgc
caggaaggggagaacgtcctcacccccgaggcgctcggcctccacctccaggcagccctc
accgccagtaaagtgcaagtatcactctacggaaagtcctgggatttgaacaaaatctgc
tacaagtcagggattcccctaattgaaaatggaatgattgagcggatgatagagaagctg
tttccgtgcgtgatcctcacccccctcgactgcttctgggagggcgccaagctccaaggg
ggctcagcctacttgcctggccgccctgacatccagtggaccaacctggatccagagcag
ctgctggaggagctggggccctttgcctccctcgagggcttccgggagctgctagacaag
gcacaggtgggccaggcctatgtggggcggccctgtctgcaccctgacgacctccactgc
ccgcctagtgcccctaaccatcacagcaagcaggctcccaacgtggctcaggagttgagt
gggggctgtcacggcttttcccacaagttcatgcactggcaggaggaactgctgctgggg
ggcatggccagagacccccaaggacagctgctgagggcggaggccctgcagagcaccttc
ctgctgatgagtccccgccagctgtacgagcacttccggggcgactaccagacgcatgac
atcggctggagcgaggagcaggcggggacagtgctacaggcctggcagcggcgcttcgtg
caggtcagtgtgcggatgggcaagggcggtgcccgaggctgctccctcctcctgcccctc
agatccaccctgtctctgcagctggctcaggaggccctgcctcagaattcatcccagcag
atccatgccttttcctccaccactctggatgacatcctgcatgctttctctgaagtcagt
gctgcccgtgtggtcggaggctatctgctcatgctagcctatgcttgcgtgacgatgctg
cgctgggactgtgcccagtcccagggtgccgtgggccttgcgggggtgctgctggtagcc
ctggcggtggcctcgggccttgggctctgcgccctgctgggcatcgccttcaatgccgcc
actacccaggtgctgcccttcttggcactgggcatcggcgtggatgacatattcctgctg
gcacatgccttcacagaggctccacctggcacccctctccaggagcgcacaggtgagtgt
ctgcagcgcacgggcaccagcgtcgcactcacgtccatcagccacatggttgccttcttc
atggccgccctggttcccatcccggccctgcgggccttctccctgcaggcagccatagtc
gttggctgcaactttgcagccgtgatgcttgtcttcccagcggtcctcagtctggacctg
caccgacgccactgccagcgccttgacgtgctctgctgcttctctagcccctgctctgcg
cgggtaattcagatcctgccccaggaactgggggacgggacggtgccagtgggcatcgcc
cacctgaccgccacggttcaagcctttgcccactgcgaagccggcagccagcacgtcgtc
accatcctgcctccccgagcccgcttggtgcccccaccttctgacccactgggctctgag
ctcttcagcccaggaggatccacacgggaccttctaggccaagaggaggggacgagacaa
aaggcaacctgcagctccctgccctgtgcccgctggaatcttgcccattttgcccgctct
cagtttgcacccttgctgctccagtcacacagcaaggccatcgtgctggtgctctttggg
gctctcctgggcctgagcctctacggagcaaccttggtgcaggatgggctggccctgacg
gatgtggtgcctcggggcaccaaggagcacgccttcctgagcgcccagctcaggtacttc
tccctgtacgaggtggccctggtgacgcagggtggctttgactacgcccactcccaacgc
gccctctttgatctgcaccagcgcttcagctctctcaaggccgtgctgcccacacctgcc
acccaggcgccgcgcacctggctacactattaccggaactggctcctgggaatccaggcc
gcctttgaccaggactgggcttctgggcgcattagccgccactcgtgccgcaatggctcc
gaggacggggccctggcctacaagctgctcctccagaccggggatgcccaagagcctctg
gatttcagccagctgaccacacggaagctggtagacaaggaggggctgattgcacctgag
ctcttctacgtggggctgaccatgtgggtaagcagtgacccgctgggcctggcggcctca
caggccaacttctaccccccacctcccgagtggctgcacgacaagtacgacaccaccggg
gagaaccttcgcatcccggcggcccagcccctggagtttgcccagttccccttcctactg
cgtggcctccagaagactgcggactttgtggaggccatcgagggggcccgggcagcatgc
gccgaggcaggtcaggccggggtgcgcgcctaccccagcggctcccccttcctcttctgg
gagcagtatctgggcctgcggcgctacttcctgctggctatctgcatcctgctggtatgc
actttcctcgtctgtgccctgctgctgctcaacccctggacggctggcctcatcgtactg
gtcctggcgatgatgactgtggagctctttggcatcatgggtttcctgggcatcaaactg
agtgccatccccgtggtgatccttgtggcctctgtgggcattggtgttgagttcacagtc
cacgtggctctgggcttcctgaccacccagggtagccggaacctgcgggctgcccacgcc
ctagagcgcacgtttgccccagtgaccgatggggccgtgtccacgttgctgggtctgctc
atgcttgctggctccaactttgacttcatcatacggtactttttcgtggtgctaactgtg
ctcacactcctgggcctcctccatgggctcgtgctgctgcctgtgctgctgtccatcctg
ggccccccgccagaggtggtacagatgtacaaggagagcccagaggtcctcagcccccca
gctccacgagaaggagggctcaggtgggggttgccccccaccctgccccagagctttgcc
agagtgactacctccatgacggtggccctccacccacccccactgcccggtgcctacatc
cacccagcctctgacgagcccacttggtcccctgttgccacatcagctgccagcggctcc
agcaacctcagttccaggggaccatgtccagccactgggtga
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