KEGG   Canis lupus familiaris (dog): 482994
Entry
482994            CDS       T01007                                 

Gene name
ADCY3
Definition
(RefSeq) adenylate cyclase type 3
  KO
K08043  adenylate cyclase 3 [EC:4.6.1.1]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa00230  Purine metabolism
cfa01100  Metabolic pathways
cfa01522  Endocrine resistance
cfa04015  Rap1 signaling pathway
cfa04020  Calcium signaling pathway
cfa04022  cGMP-PKG signaling pathway
cfa04024  cAMP signaling pathway
cfa04062  Chemokine signaling pathway
cfa04072  Phospholipase D signaling pathway
cfa04114  Oocyte meiosis
cfa04211  Longevity regulating pathway
cfa04213  Longevity regulating pathway - multiple species
cfa04261  Adrenergic signaling in cardiomyocytes
cfa04270  Vascular smooth muscle contraction
cfa04371  Apelin signaling pathway
cfa04540  Gap junction
cfa04611  Platelet activation
cfa04713  Circadian entrainment
cfa04714  Thermogenesis
cfa04723  Retrograde endocannabinoid signaling
cfa04724  Glutamatergic synapse
cfa04725  Cholinergic synapse
cfa04727  GABAergic synapse
cfa04740  Olfactory transduction
cfa04750  Inflammatory mediator regulation of TRP channels
cfa04911  Insulin secretion
cfa04912  GnRH signaling pathway
cfa04913  Ovarian steroidogenesis
cfa04914  Progesterone-mediated oocyte maturation
cfa04915  Estrogen signaling pathway
cfa04916  Melanogenesis
cfa04918  Thyroid hormone synthesis
cfa04921  Oxytocin signaling pathway
cfa04923  Regulation of lipolysis in adipocytes
cfa04925  Aldosterone synthesis and secretion
cfa04926  Relaxin signaling pathway
cfa04927  Cortisol synthesis and secretion
cfa04928  Parathyroid hormone synthesis, secretion and action
cfa04934  Cushing syndrome
cfa04935  Growth hormone synthesis, secretion and action
cfa04962  Vasopressin-regulated water reabsorption
cfa04970  Salivary secretion
cfa04971  Gastric acid secretion
cfa04972  Pancreatic secretion
cfa04976  Bile secretion
cfa05032  Morphine addiction
cfa05163  Human cytomegalovirus infection
cfa05166  Human T-cell leukemia virus 1 infection
cfa05200  Pathways in cancer
cfa05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    482994 (ADCY3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    482994 (ADCY3)
   04371 Apelin signaling pathway
    482994 (ADCY3)
   04020 Calcium signaling pathway
    482994 (ADCY3)
   04072 Phospholipase D signaling pathway
    482994 (ADCY3)
   04024 cAMP signaling pathway
    482994 (ADCY3)
   04022 cGMP-PKG signaling pathway
    482994 (ADCY3)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    482994 (ADCY3)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    482994 (ADCY3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    482994 (ADCY3)
   04062 Chemokine signaling pathway
    482994 (ADCY3)
  09152 Endocrine system
   04911 Insulin secretion
    482994 (ADCY3)
   04923 Regulation of lipolysis in adipocytes
    482994 (ADCY3)
   04912 GnRH signaling pathway
    482994 (ADCY3)
   04913 Ovarian steroidogenesis
    482994 (ADCY3)
   04915 Estrogen signaling pathway
    482994 (ADCY3)
   04914 Progesterone-mediated oocyte maturation
    482994 (ADCY3)
   04921 Oxytocin signaling pathway
    482994 (ADCY3)
   04926 Relaxin signaling pathway
    482994 (ADCY3)
   04935 Growth hormone synthesis, secretion and action
    482994 (ADCY3)
   04918 Thyroid hormone synthesis
    482994 (ADCY3)
   04928 Parathyroid hormone synthesis, secretion and action
    482994 (ADCY3)
   04916 Melanogenesis
    482994 (ADCY3)
   04925 Aldosterone synthesis and secretion
    482994 (ADCY3)
   04927 Cortisol synthesis and secretion
    482994 (ADCY3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    482994 (ADCY3)
   04270 Vascular smooth muscle contraction
    482994 (ADCY3)
  09154 Digestive system
   04970 Salivary secretion
    482994 (ADCY3)
   04971 Gastric acid secretion
    482994 (ADCY3)
   04972 Pancreatic secretion
    482994 (ADCY3)
   04976 Bile secretion
    482994 (ADCY3)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    482994 (ADCY3)
  09156 Nervous system
   04724 Glutamatergic synapse
    482994 (ADCY3)
   04727 GABAergic synapse
    482994 (ADCY3)
   04725 Cholinergic synapse
    482994 (ADCY3)
   04723 Retrograde endocannabinoid signaling
    482994 (ADCY3)
  09157 Sensory system
   04740 Olfactory transduction
    482994 (ADCY3)
   04750 Inflammatory mediator regulation of TRP channels
    482994 (ADCY3)
  09149 Aging
   04211 Longevity regulating pathway
    482994 (ADCY3)
   04213 Longevity regulating pathway - multiple species
    482994 (ADCY3)
  09159 Environmental adaptation
   04713 Circadian entrainment
    482994 (ADCY3)
   04714 Thermogenesis
    482994 (ADCY3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    482994 (ADCY3)
  09165 Substance dependence
   05032 Morphine addiction
    482994 (ADCY3)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    482994 (ADCY3)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    482994 (ADCY3)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    482994 (ADCY3)
   05163 Human cytomegalovirus infection
    482994 (ADCY3)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    482994 (ADCY3)
Enzymes [BR:cfa01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     482994 (ADCY3)
SSDB
Motif
Pfam: Guanylate_cyc AC_N HNOBA Peptidase_S49_N
Other DBs
NCBI-GeneID: 482994
NCBI-ProteinID: XP_540108
Ensembl: ENSCAFG00000004090
VGNC: 37620
LinkDB
Position
17
AA seq 1145 aa
MPRNQGFSEPEYSAEYSAEYSVSLPSDPDRGVGRTHEISVRTSGPCLCLPRFMRLTFVPE
SLENLYQTYFKRQRHETLLVLVVVAALFDCYVVLMCAVVFSSDKLAPLLVAAVGLLLDIL
LFVLCKKGLLPDRVTRKVVPYLLWLLITAQVFSYLGLNFAGAHAASDTVGWQAFFVFSFF
ITLPLSLSPIVIISVVSCVVHTLVLGVTVAQQQQDGLQGMRLLREILANVFLYLCAIVVG
IMSYYMADRKHRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKDMKKDES
QKDQQQFNTMYMYRHENVSILFADIVGFTQLSSACSAQELVKLLNELFARFDKLAAKYHQ
LRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAISYVREKTKTGVDMRVGVHTGTV
LGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTMDCLKGEFDVEPGDGGSRCE
YLDEKGIETYLIIASRPEVKKTAARRGPAGPPLLNGAPASSKPSSPALIETKEPNGSIHT
SGSTSEEPEEQDAQADNPSFPNPRRRLRLQDLADRVVDASEDEHELNQLLNEALLERESA
QVVKKRNTFLLSMRFMDPEMETRYSVEKEKQSGAAFSCSCVVLLCTALVEILIDPWLMTN
YMTFVVGEVLLLILTICSLAAIFPRAFPKKLVAFSTWIDRTRWARNTWAMLAIFILVMAN
VVDMLSCLQYYTGPHNSTAGLEVDDGCVENPKYYNYVAVLSLIATIMLVQVSHMVKLTLM
LLVTGAVAVINIYAWRPIFDEYDRKRFQEHDFPMVALEKMQELSTSGLNGTVRLPLVPSK
YSMTVMIFVMMLSFYYFSRHVEKLARTLFLWKIEVHDQKERVYEMRRWNEALVTNMLPEH
VARHFLGSKKRDEELYSQSYDEIGVMFASLPNFADFYTEESINNGGIECLRFLNEIISDF
DSLLDNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFASSNKEEKSDKERWQHLADLADF
ALAMKDTLTNINNQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGV
MGNIQVVEETQAILREYGFRFVRRGPIFVKGKGELLTFFLKGRDKPAAFPNGSSVTLPHQ
VVDNS
NT seq 3438 nt   +upstreamnt  +downstreamnt
atgccgaggaaccagggcttctccgagcccgagtactcggccgagtactccgccgagtac
tctgtgagcctgccctccgaccccgaccgcggcgtgggccggacccacgaaatctcggtc
cggacctccggcccctgcctctgcctgccgcggttcatgcggctgaccttcgtgcccgag
tccttggagaacttgtaccagacctacttcaagcggcagcgccacgagaccctgctggtg
ctggtggtggtcgcggccctcttcgactgctacgtggtgctcatgtgcgcggtggtcttc
tccagcgacaagctggctccgctcctcgtggccgcggtgggcctgctgttggacatcctc
ctcttcgtgctctgcaaaaaggggctgctccccgaccgggtcacccggaaagtggtgccc
tacctgctgtggctgctgatcactgcccaggttttctcctacctgggcctgaacttcgcg
ggcgcccatgcggccagcgacacggtgggctggcaggccttctttgtcttctccttcttc
atcacgctgccgctcagcctcagccccatcgtcatcatctcggtggtctcctgtgtggtg
cacacgctcgtcttgggggtcaccgtggcccagcagcagcaggacgggctgcagggcatg
cgtttgctgagggagatcctggccaacgtcttcctctacctgtgcgccatcgtcgtgggc
atcatgtcctactacatggccgaccgcaagcaccgaaaagccttcctggaggcccgccag
tcactagaggtgaagatgaatctggaggagcagagccagcagcaggagaaccttatgctt
tccatcctgcccaagcatgtggctgatgagatgctgaaggacatgaagaaggacgagagc
cagaaggaccagcagcagttcaacaccatgtacatgtaccgccacgagaacgtcagcatc
ctcttcgcggacatcgtgggcttcacccagctgtcttctgcctgcagtgcccaggagctc
gtgaagctgctcaacgagctctttgcccgcttcgacaagctggcggccaaataccaccag
ctgcggattaagatcctaggggactgttactactgcatctgcggcctgcccgactaccgg
gaggaccacgccgtctgctccatcctcatggggctcgccatggtggaggccatctcgtat
gtgcgagagaagacgaagaccggagtggacatgcgcgtgggggtgcacacgggcaccgtg
ctggggggcgtcctgggccagaagcgctggcagtacgacgtgtggtctaccgacgtcacc
gtggccaacaagatggaggccggtggcatccccgggcgggtgcacatctcccagagtacc
atggactgcctgaagggcgagttcgacgtggagccgggcgacgggggcagccgctgtgag
tacctggacgagaagggcatcgagacctacctcatcatcgcgtccaggcccgaggtgaag
aagacagcggcccgccgcggccccgccggcccgcccctgctaaatggagcgccagcttct
tccaagcccagctcccccgccctcattgaaaccaaggagcccaacgggagcatccacacc
agcggctccacatcggaggagcccgaggaacaggacgcccaggccgacaacccttcgttc
cccaacccacgtcggaggctgcgcctgcaggacctggccgaccgggtggtggacgcctca
gaggatgagcatgagctcaaccagctgctcaacgaggccctactggagcgcgagtctgcc
caggtagtgaagaagagaaacaccttcctcctctccatgcggttcatggaccctgagatg
gaaacccgctactcagtggagaaggaaaagcagagcggggctgccttcagctgctcctgc
gttgtcctgctctgtacggccctggtcgagatactcatcgacccctggctaatgacaaac
tacatgacctttgtggttggggaggttctacttctgatcctgacaatctgctcgctggct
gccatctttccccgggcctttcctaagaagctcgtcgccttctcgacttggatcgaccgg
acccgctgggccaggaacacatgggccatgttagccatcttcattctggttatggccaac
gtcgtggacatgcttagctgtctccagtactacacaggaccacacaacagcactgcaggg
ttggaggtggacgatggctgcgtagagaaccccaagtattacaactatgttgccgtgctg
tccctcatcgctaccatcatgctggtgcaggtcagccacatggtgaaactcacgctcatg
ctactcgtcacgggtgctgtggccgtcatcaacatctatgcctggcgccccatctttgac
gaatacgaccgcaaacgtttccaggaacatgactttcccatggtcgccttagagaagatg
caggaattgtccacctctgggctcaatggcactgtcaggctgcccctggtgccttccaag
tactccatgacagtgatgatcttcgtcatgatgctgagcttttactacttctcacgccac
gttgaaaaactggcaaggacactgtttttgtggaagattgaggtccatgaccagaaggaa
cgtgtctacgagatgcggcgctggaatgaggccttggtcaccaacatgttgcctgagcac
gtggcacgccacttcctggggtccaagaagagggatgaggagctgtatagccagtcttac
gatgagattggagtcatgtttgcctctctacccaactttgccgacttctacacagaggag
agcatcaataatggtggcattgagtgtctgcgcttcctcaatgagatcatctcagacttt
gattctcttctggacaatcccaaattccgggtcatcaccaagatcaaaaccattggcagc
acctatatggcagcttcaggagtcaccccagatgtcaacaccaacggctttgccagctcc
aacaaggaggagaagtcagacaaagagcgctggcagcacctggctgatctggctgacttt
gctctagccatgaaggatacactcacgaacatcaacaaccaatccttcaacaactttatg
ctgcgcataggcatgaacaaaggaggggtactggctggggtcattggagcccggaaacca
cactatgacatctggggcaatactgtcaatgtggccagcaggatggagtccacaggggtc
atgggcaacattcaggtggtggaagaaacacaagccatccttcgagagtacggcttccgc
tttgtgaggcgagggcccatctttgtgaaagggaagggggagctgctcacctttttcttg
aaggggcgtgacaagccagctgccttccctaatggctcctccgtcaccctgccccaccag
gtggtggacaactcctga

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