Canis lupus familiaris (dog): 486558
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Entry
486558 CDS
T01007
Symbol
KMT2D
Name
(RefSeq) histone-lysine N-methyltransferase 2D isoform X1
KO
K09187
[histone H3]-lysine4 N-trimethyltransferase MLL2 [EC:
2.1.1.354
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa00310
Lysine degradation
cfa01100
Metabolic pathways
cfa04934
Cushing syndrome
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
486558 (KMT2D)
09160 Human Diseases
09167 Endocrine and metabolic disease
04934 Cushing syndrome
486558 (KMT2D)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
cfa03036
]
486558 (KMT2D)
Enzymes [BR:
cfa01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.354 [histone H3]-lysine4 N-trimethyltransferase
486558 (KMT2D)
Chromosome and associated proteins [BR:
cfa03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
486558 (KMT2D)
HMT complexes
MLL-HCF complex
486558 (KMT2D)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PHD
SET
FYRC
FYRN
zf-HC5HC2H
zf-HC5HC2H_2
HMG_box
Motif
Other DBs
NCBI-GeneID:
486558
NCBI-ProteinID:
XP_005636940
Ensembl:
ENSCAFG00000008718
VGNC:
42491
LinkDB
All DBs
Position
27:complement(40701293..40740498)
Genome browser
AA seq
5660 aa
AA seq
DB search
MDSQKPPGEDKDSEPAADGPAASEESGTTEPDLPNPYVGEVSVPSSGGPRLQEPPRDCSG
GPVRRCALCNCGEPSLHGQRELRRFELPFDWPQCPVVSPGGNPGPNEAVLPSEDLSQIGF
PEGLTPAHLGEPGGSCWAHHWCAAWSAGVWGQEGPELCGVDKAIFSGISQRCSHCTRLGA
SIPCRSPGCPRLYHFPCATASGSFLSMKTLQLLCPEHSEGAAHLEEARCAVCEGPGELCD
LFFCTSCGHHYHGACLDTALTARKRAGWQCPECKVCQACRKPGNDSKMLVCETCDKGYHT
FCLKPPMEELPAHSWKCKACRVCRACGAGSAELNPNSEWFENYSLCHRCHKAQGGQLIGS
VAEQHPPVCSRFSPLEPGDTPTDEPKALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLG
RAGAQLEPRLEVPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEESPLSPPP
EESPLSPPPESSPFSPLEESPFSPPEESPPSPPLETPLSPPPEASPLSPPFEESPLSPPP
EELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLS
PPPEASRLSPPPEDSPMSPPPEDSPVSPPPEVSCLSSLPEVSRLSPPPEESPLSPPPEES
PTSPPPEASRLFPPPEDSPTSPPPEDSPASPPPEDLLMTLPLEESSLLPLPEEPRLCPLP
EEPRLPPQPEEPRLSPRPEEPRLSPQPEEPRLSPRPEEPRLSPQPEEPRLSPALEEPCLS
PAPEELRLPLWLEEPRLSPRPEKPCLAPAPEALHLSPRPEEPCLSPRPEEPRLSPRPEEP
RLSPRPEEPRLSPRSEEPCLSPRPEEPRLSPMPEEPQLSPRPEEPPLSPMPEEPPLSPGP
EEPRLSPRPEEPRPSPQPEEPRLSLGPEEPRLSPRPEEPCLSPRPEEPRLSPRPEEPPEE
PGLCPAPEELPLFLPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLM
PPDPLPPPLSPIITTVAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANC
TDPEPVPPMILPPSPGSPMGPASPILMEPLPSRCSPLLQPSLPPQNSPPSQCSLPALPLS
VPSPLSPMEKAVEVSDEAEPHEMETEKVPEPECPALEPSPTSPLPSPMGNLSCPAPSPAP
ALDDFSGLGEDTAPLDGTDTPGSQPEAGQTPGSLASELKGSPVLLDPEELAPVTPMEVYG
PEGKQAGQGSPCEEQEEPRVPVAPTPPTLIKSDIVNEISNLSQGDASASFPGSEPLLGSP
DPEGGGSLSMELGVSTDVSPARDEGSLRLCTDSLPETDDSLLCDAGTAIGGGKAEGDKGR
RRSSPARSRIKQGRSSSFPGRRRPRGGAHGGRGRGRARLKSTTSSIETLVVADIDSSPSK
EEEDDDDDTMQNTVVLFSNTDKFVLMQDMCVVCGSFGRGAEGHLLACSQCSQCYHPYCVN
SKITKVMLLKGWRCVECIVCEVCGQASDPSRLLLCDDCDISYHTYCLDPPLLTVPKGGWK
CKWCVSCMQCGAASPGFHCEWQNSYTHCGPCASLVTCPICHTPYVEEDLLIQCRHCERWM
HAGCESLFTEDDVEQAADEGFDCVSCQPYVVKPAAPVAPPELVPMKVKEPEPQYFRFEGV
WLTETGMAVLRNLTMSPLHKRRQRRGRLGLPGEAGLEGSEPSDALGPDDKKDGDLDTDEL
LKGEGGVEHMECEMKLEGPVSPDVEPGREETEESKKRKRKPYRPGIGGFMVRQRKSHTRV
KKGPAAQAEVLSGDGQPDEVMPVDLPVEGPVDQSLADGDEKKKQQRRGRKKSKLEDMFPA
YLQEAFFGKELLDLSRKALFAVGMGRPTFGLGTPKAKGDGGSDRKELPTSQKGDDGPDVA
DEESRGPEGKADTPGPEDGGVKASPVPSDPEKPGTPGEGMLSSDLDRIPTEELPKMESKD
LQQLFKDVLGSEREQHLGCGTPGPDGSRTPLQRPFLQGGLPLGNLPSSSPMDSYPGLCQS
PFLDSRERGGFFSPEPGEPDSPWTGSGGTTPSTPTTPTTEGEGDGLSYNQRSLQRWEKDE
ELGQLSTISPVLYANINFPNLKQDYPDWSSRCKQIMKLWRKVPAADKAPYLQKAKDNRAA
HRINKVQKQAESQINKQTKVGDMARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPT
TPAGLSTSADGFLKPPVGTVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYALEPRFP
TAPPTYPPYPSPTGAPAPPLTLGASSRPGTGQPGEFHTTPPGTPRHQPSTPDPFLKPRCP
SLDNLAVPESPGIGGGKAAEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSP
SSGPHLGSLELKAPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSSPSHSDIFR
PGPYPDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPL
SAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGPLAHTPLG
AGGFPAALPSGPTGELHAKVPSGQPPNFARSPGTGAFVGTPSPMRFTFPQAVGEPSLKPP
VPQPGLPPPHGINSHFGPGPTLGKPQSTNYAVATGNFHPSGSPLGSSSGSTGEGFGLSPL
RPPSVLPTPAPDGSLPYLSHGASQRAGITSPVDKREDPGAGMGGSLVAPELPGTQDPSLS
SLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFE
QLSRGQTPFAGTQDKSSLVGLPPSKLGGPILGPGAFPGDDRLSRPPPPATPSSLDVNSRQ
LVGGSQAFYQRAPYPGSLPLQQQQQQQQLWQQQQQQQQQATAATSMRLAMSTRFPSTPGP
ELGRPALGSPLAGLPTRLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGAPFPGQGPPQR
PRFYPVSEDSHRMAPEGLRGLAVSGLPPQKPSAPPAPELNNSVHPIPHTKGPSLPTSLEL
VSRPPSSTELGRPPPLALEAGKLPCEDPELDDEFDAHKALEDDEELAHLGLGVDVAKGDD
ELGTLENLETNDPHLDDLLNGDEFDLLAYTDPELDTGDKKDIFNEHLRLVESANEKAERE
ALLRGVEPVSLGPEERPPPAADASEPRLASVLPEVKPKVEEGGRHPSPCQFAITTPKVEP
APATTSLSLGLKPGQSVMGSRDTRMGTGPFSSSGHTTEKGPFGATGGPPAHLLTPSPLSG
PGGSSLLEKFELESEALTLPGGHTASGDELDKMESSLVASELPLLIEDLLEHEKKELQKK
QQLSAQLQPVQQQQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLSGPQQQLALGLGGS
RQPGLAQPLMPTQPPAHALQQRLAPSMAMVSNQGHMLSGQHGGQAGLVPQQSSQPVLAQK
PMGTMPPSMCMKPQQLAMQQQLANSFFPDTDLDKFAAEDIIDPIAKAKMVALKGIKKVMA
QGSIGVAPGMNRQQVSLLAQRLSGGPGSDLQNHVAAGSGQERSAGDPSQPRPNPPTFAQG
VINEADQRQYEEWLFHTQQLLQMQLKVLEEQIGVHRKSRKALCAKQRTAKKAGREFPEAD
AEKLKLVTEQQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALS
PSQSPRLLTKLPGQLLPGHGLQPPQGPPGGQATGLRLPPGGMTLPGQPGGPFLNTSLAQQ
QQQQHSGGAGALGGPSGGFFPGNLALRGLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQ
HLLGQVAVQQQQQQSLGVQANQALGPKPQGLLPPSSRQGLLVQQLSPQPPQGPQGMLGPA
QVAVLQQQQQQQHPGALGPQGPHRQVLLTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQ
QQQQQQQQHQQQGSMAGLSHLQQGLMPHGGQPKLSTQPMAALQQQQLQQQQQQQQQQLQQ
QQQQQQQLQQQQQQQLQQQQQQQLQQQQLQQQQQFQQQQQQLQQQQQQQFQQQQQQQQQQ
QQQQQQQMGLLNQSRTLLSPQQQQPQQPQQQVPLGPGMPAKPSQHFSSPGALGTTVLLTG
KEQSMVETALPPEATEGPSTHQGAPLALGTVPESAATEPGEVKPSLSGDSQLLLVQPQTQ
PQPSSAQLQPPLRLPGPQQQQVNLLHTATVGSHGQAGSGSSSEASPMPHLLAQSSVPLGE
QPGTMTQNLLGSQQPLGLERPVQNNAGPQPAKAGSVPQSGPGLPGPGVMPTVGQLRAQLQ
GVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQAPPYQEPGAQPSPLQGLLGRQPQ
LGGFPGSQTGPLQELGVGLRPQGPPRLPAPQGALATGPVLGPVHPTPPPSSPQEPKRPSS
QPPGASPLVPSQLPSEAQLPPTQPGTPKPQGPSLELPPGRVSPAAAQLADTFFGKGLGPW
DPPDSLVEAQKPEQSSLVPGHLEQVNGQAVPEPPHLSIKQEPREEPCALGAQAVKREANG
EPIGAPGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQLSTGRGPEGLRAEINGHIDSKLAG
LEQKLQGTPSNKEDTAARKPVTPKPKRVQKASDRLVSSRKKLRKEDGVRASEALLKQLKQ
ELSLLPLTEPTITANFSLFAPFGSGCPVNGQCQLRGAFGSGALPTGPDYYSQLLTKNNLS
NPPTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDTEGTLRDASEVKSLDLL
AALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPQLGSGRWEQEDRAL
SPVIPIIPRASIPVFPDTKPYGALDLETSGKLPATTWEKGKGSEVSVMLTVSAAAAKNLN
GVMVAVAELLSMKIPNSYEVLFPESPARAGIEPKKGEAEGPGGKEKGLGGKSPEAGPDWL
KQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPP
PSPLAPSPASPPAEPLVELPAEPSAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRPP
RLKKWKGVRWKRLRLLLTIQKGSGRQEDEREVAEFMEQLGTALRPDKVPRDMRRCCFCHE
EGDGATDGPARLLNLDLDLWVHLNCALWSTEVYETQGGALMNVEVALHRGLLTKCSLCQR
TGATSSCNRMRCPNVYHFACAIRAKCMFFKDKTMLCPMHKIKGPCEQELSSFAVFRRVYI
ERDEVKQIASIIQRGERLHMFRVGGLVFHAIGQLLPHQMADFHSATALYPVGYEATRIYW
SLRTNNRRCCYRCSIGENNGRPEFVIKVMEQGLEDLVFTDASPQAVWNRIIEPVAAMRKE
ADMLRLFPEYLKGEELFGLTVHAVLRIAESLPGVESCQNYLFRYGRHPLMELPLMINPTG
CARSEPKILTHYKRPHTLNSTSMSKAYQSTFTGETNTPYSKQFVHSKSSQYRRLRTEWKN
NVYLARSRIQGLGLYAAKDLEKHTMVIEYIGTIIRNEVANRREKIYEEQNRGIYMFRINN
EHVIDATLTGGPARYINHSCAPNCVAEVVTFDKEDKIIIISSRRIPKGEELTYDYQFDFE
DDQHKIPCHCGAWNCRKWMN
NT seq
16983 nt
NT seq
+upstream
nt +downstream
nt
atggacagccagaagccgcctggtgaggataaagattcagaaccggcagctgatggacct
gcagcctctgaggagtcaggcaccactgagccagaccttcccaacccatatgtgggggag
gtctctgtgcccagttctggaggtcctaggcttcaggagcctccccgggactgcagtggg
ggtccagtgcggcgttgtgctctctgtaactgcggggagcctagtctacatgggcagcgg
gaactacggcgctttgagttgccatttgactggccccagtgtccagtggtgtcccctggg
gggaacccagggcccaacgaggcagtgctgcccagtgaggacctgtcacagattggtttc
cctgagggcctgacacctgcccacctaggagaacctggagggtcctgctgggctcaccat
tggtgtgctgcgtggtcggcaggtgtatgggggcaggagggcccagaactatgtggtgtg
gacaaggccatcttctcagggatctcacagcgctgctcccactgcaccaggctcggtgcc
tccatcccttgccgctcacccggatgtccacggctttaccacttcccttgtgcgactgcc
agcggttccttcttatccatgaaaacactgcagctgctatgcccggagcacagtgagggg
gctgcacatctggaggaggctcgttgtgcagtatgcgaggggccaggggagttgtgtgac
ctgttcttctgtaccagttgtgggcatcactatcacggggcctgcctggacactgctctt
accgcccgcaagcgtgctggctggcagtgccctgaatgcaaagtgtgccaagcctgcagg
aaacctgggaatgactctaagatgttggtctgtgagacgtgtgacaaaggataccatacc
ttctgcctcaagccaccaatggaggaattgccagctcactcttggaagtgcaaggcatgc
cgggtatgccgggcctgtggggcaggctcagcggagctgaatcccaactctgagtggttt
gaaaactactcactctgtcaccgctgtcacaaggcccagggaggacagcttattggttct
gtggctgagcagcatccccctgtctgcagcaggttctcacccctagagcctggcgatacc
cccactgacgagcccaaagctctgtacgttgcatgccaagggcagccaaagggtgggcac
gtgacctccatgcaacccaaggaaccggggcccctgcaatgtgaagccaaaccactaggg
agagcaggggcccaacttgagccccggttggaggtccccctaaacgaggagatgccactg
ctgcccccacctgaggagtcgcccctctccccaccacctgaggaatcgcccacatcccca
ccacctgaggcatcgcgtctgtccccaccaccggaggaatcacccctctctccgccgcct
gaggagtctcctctgtctcctccacctgaatcatcacctttttctccactggaggagtcg
ccgttctctccaccagaggagtcacccccatctcccccacttgagacgcccctgtctcca
ccgcctgaagcatcacccctctccccaccatttgaagagtctcccttatcccccccacct
gaggagttgcccacttccccgccacctgaagcatctcgcctgtctccaccacctgaggag
tcacccatgtccccgccacctgaagagtcacccatgtctccgccacctgaagcatctcgt
ctgttcccaccatttgaagaatcgcccctgtcccctccaccagaggagtctcccctctcc
ccaccacctgaggcatcccgtctgtccccacctcctgaggactcgcctatgtccccacca
cctgaagactcgcctgtgtcccccccacctgaggtatcctgcctgtcctccctgcctgag
gtgtcacgcctgtccccaccacctgaggaatctcccctgtccccaccacccgaagagtcc
cccacatcccctccacctgaggcttcccgcctgttcccaccacctgaggactccccgact
tccccgccgcctgaagactcacctgcttctccgccaccggaggacttactcatgacccta
ccgctagaggagtcatccctgttgccactgcccgaggagccacgactctgccccctgccc
gaggagccgcgcctgccccctcagcccgaggagccgcgcctgtcccctcggcctgaggag
ccgcgcctgtcccctcagcccgaggagccacgcctgtcccctcggcccgaggagccgcgc
ctgtcccctcagcctgaggagccgcgcctgtcccccgcacttgaggaaccatgcctgtcc
cccgcgcctgaggagctgcgcctgcccctttggcttgaggagccacgtctgtccccccgg
cctgagaagccatgcctggcccctgcccctgaggcgctgcacctgtccccccggcctgag
gagccctgcctgtccccccggcctgaggaaccgcgcctgtccccccggcctgaggaaccg
cgcctgtccccccggcctgaggagccgcgcctgtccccccggtctgaggagccgtgcctg
tccccacggcctgaggagccacgcctgtcccccatgcctgaggagccgcagttgtctccc
cggcctgaggagccgcccctgtcccccatgcctgaggagccgcccctgtcccccgggcct
gaggagccgcgcctgtccccccggcctgaggagccacgcccgtcccctcaacctgaggaa
ccgcgcctgtcccttggacctgaggaaccgcgcctgtcccctcgacctgaggaaccgtgc
ctgtcccctcgacctgaggaaccgcgcctgtcccctcgacctgaagagccccctgaggag
ccaggcctatgccctgcacctgaggaattgcccttgttcctcccacctggggagccatct
ttatcccccttgcttggagagccggccctgtctgagcctggggaaccacctctgtcccct
ctaccagaggagttgccgttgtccccatccggggagccatccttgtcacctcagctgatg
ccaccagatcctcttcctcctccgctctcacccattatcacaactgtggccccgccggct
ctgtctcctttgggggagttagaatacccctttggtgccaaaggggacagtgaccctgag
tcgccgttggctgcccccatccttgagacgcccatcagccctccaccagaagctaactgc
actgaccctgagcctgtgccccctatgatcctccccccatctccaggctccccaatggga
ccagcctctcccatcctgatggagccccttccctctcggtgttctccactcctgcaacct
tcccttcctccccaaaactctcctccttcccaatgttctcttcctgctctgccattgtcc
gttccctccccactgagtcccatggagaaggcagtggaggtctcagatgaggctgagccg
catgagatggagactgagaaagtcccagaacctgagtgtccagccttggaacccagcccc
actagtcctctcccctcgcccatggggaacctttcctgccccgcacccagccctgcccca
gctctggatgacttctctggtctgggggaagacacagcccctctggatgggactgacact
cctggttcacagccagaggctggacagacccctggcagtttggctagtgaacttaagggt
tcccctgtgctcctggaccccgaggagctggcccccgtgacccctatggaggtctatggc
ccagaaggcaagcaggcagggcagggttcaccctgtgaagagcaagaggagccacgtgta
ccggtggcccctaccccacccactctcatcaaatccgacatcgttaatgagatctctaat
ctgagccagggtgatgccagtgccagttttcctggctcagagcccctgctaggctctccc
gaccccgaggggggcggctccttgtccatggagctgggggtatctacagacgttagtcca
gcccgggatgagggctccctgcggctctgtactgactcgctgccagagactgacgactcg
ctactatgtgatgctgggacagcaattggcggaggcaaagccgagggggacaaggggagg
cggcgcagctccccggctcgttcccgcatcaaacagggtcgcagcagtagtttcccagga
agacgccggccacgtggaggagcccatggaggacgtgggagaggacgggcccggctaaaa
tcaactacttcttccattgagactctggtagttgctgatatcgatagctctcccagcaaa
gaggaagaagacgacgatgacgacaccatgcaaaatactgtggttctcttctccaacaca
gacaagtttgtcctaatgcaggacatgtgcgtggtttgtggcagctttggccggggggca
gagggccacctccttgcctgttcccagtgttcccagtgctatcacccttactgtgtcaac
agcaagatcaccaaggtgatgctgctaaagggctggcgttgcgtggagtgcatcgtgtgt
gaggtgtgtggccaagcctcggacccctcacgcctgctgctctgtgatgactgtgacatt
agctaccacacatactgcctggacccgccactgctcaccgtgcccaaggggggctggaag
tgcaagtggtgtgtgtcttgtatgcagtgtggggccgcctcccctggcttccactgtgaa
tggcaaaatagttacacacactgcggcccctgcgccagcctggtgacctgccctatctgt
cacaccccatacgtggaagaggacctactaatccagtgccgccactgtgaacggtggatg
catgctggctgcgagagcctcttcacggaggatgacgtggagcaggcggccgatgagggc
tttgactgtgtctcctgccagccctatgtagtaaagcctgctgcacctgtcgcacctcca
gagttggtgcctatgaaggtgaaagagccagagcctcaatactttcgcttcgagggcgtg
tggctgacagaaacgggcatggctgtgctgcgtaaccttaccatgtcacccctgcacaag
cggcgccagcggcgaggacggcttggcctcccaggcgaggcagggctggagggttctgag
ccctcagatgcccttggtcctgatgacaagaaggatggggacctggacactgatgagctg
ctcaagggtgaaggtggcgtggagcacatggaatgtgaaatgaaactggagggccctgtc
agccctgacgtggagcctggcagagaggaaactgaggaaagcaagaaacgcaaacgcaaa
ccctatcggcctggcatcggtggtttcatggtgcgacagcggaaatcccacacacgtgtg
aaaaaggggcctgctgcacaggcggaggtgttgagtggggatgggcagcccgacgaggtg
atgcctgtggacctgcctgttgagggccctgtggaccagagcttagctgatggggatgag
aaaaagaagcagcagaggcgagggcgcaagaagagcaaactggaagacatgtttcctgct
tatttgcaggaagccttctttgggaaggagctgttggacctgagccggaaggcccttttt
gcagttgggatgggccggccaacttttggcctaggaaccccaaaagccaaaggggatgga
ggctcagataggaaggagctccccacctcacagaaaggagatgatggtccggatgttgca
gatgaagaatcccgtggccctgagggcaaggctgatacaccaggacctgaggatggaggt
gtgaaggcatccccagtgcccagtgaccccgagaagcctggcactccgggtgaagggatg
cttagctctgacttagataggattcccacggaagaactgcccaagatggaatccaaggac
ctgcagcagctcttcaaggatgttctgggttctgaacgagagcagcacctgggttgcgga
acccccggcccagatggcagccgtacaccgctgcagaggccctttctccaaggtggactc
cctttgggcaatctcccctccagcagcccaatggactcctacccaggcctctgccagtcc
ccatttctggattctagggagcgcgggggcttctttagcccggaacccggtgagccagac
agcccctggacaggctcggggggcaccacgccctccacccccaccacccccaccacggag
ggtgagggcgacgggctctcctataaccagcggagccttcagcgctgggagaaggatgag
gagttgggccagctctccaccatctcgcctgtgctctatgccaacattaactttcccaat
ctcaagcaggattacccagactggtctagccgttgcaaacaaatcatgaagctctggaga
aaagttccagctgctgacaaagccccctacctgcaaaaggccaaagataaccgggcggct
caccgcatcaacaaggtgcaaaagcaggctgagagccagatcaacaagcagaccaaggtg
ggcgacatggcccgtaagactgaccgaccagccctacatctccgcattcccccccagcca
ggggcactgggcagtccgccccctgctgctgcccccaccattttcattggcagccccaca
acccccgccggcttgtctacctctgcggacgggttcctgaagccgccagtgggcacagtg
cccggccccgactcgcccggtgagctcttcctcaagctcccaccccaggtgcccgcccaa
gtgccttcgcaggacccctttggactggcccccgcctacgctctggagcctcgcttcccc
acggcaccacctacctatcctccctatcctagtccgactggggcccccgcgccgcctctg
acgctgggcgcctcatctcgtcctgggactggccagccaggggaattccacactacccca
cctggcaccccccgacaccagccctccacacctgacccctttctcaaaccccgctgcccc
tcactggacaacctggctgtgcctgagagcccagggatagggggaggcaaggctgccgaa
cccctgctgtcacccccaccttttggcgagtctcggaaggccctagaggtgaagaaggaa
gagcttggggcatcctctccgagctacgggcccccaaacctaggctttgttgactcacct
tcctcaggcccccacctgggcagcctggagttaaaggcacccgatgtcttcaaagccccc
ctgacccctcgggcatctcaggtagagccccagagcccgggcttgggcctaaggccccag
gagccacctcctgcccaggctttggccccttcttcccccagccactcggacatctttcgc
cctggcccttaccctgatccctatgcccagccgccattgacccctcggccccaaccccca
cctcctgagagctgctgtgccctgcctcctcgctcattgccctcagaccctttctcccga
gtgcccgcgagtccccagtcccagtccagctcccagtctccgttaacaccccgtcctttg
tctgccgaggctttttgcccatcccctgttacccctcgcttccagtcccctgacccctat
tcccgtcctccctcacgccctcagtcccgtgacccatttgcccccttgcataagccaccc
cgaccccagccccctgaagttgccttcaaggctgggcctctagcccacactccactgggg
gctggcggcttcccagcagccctgccctcagggccaacaggtgagctccatgctaaggtc
ccaagtggacagcccccaaatttcgcccggtcccctgggacgggtgcttttgtgggcacc
ccctctcccatgcgtttcactttccctcaggcggtaggggagccttccctaaagccccct
gtccctcagcctggtctccctccaccccatgggatcaacagccattttgggcctggccct
accttgggcaagcctcaaagcacaaactacgcagtagccacagggaatttccacccatcg
ggcagccccctgggatccagcagcgggtccacaggagagggctttgggctgtccccgcta
cgccccccgtcagtcctacccacacctgcacccgatggatccctcccctacctgtcccat
ggagcctcacagcgggcaggcatcacctctccggtcgataagcgagaagacccaggggct
ggaatgggcggctctttggtggcacctgaacttccaggtacccaggacccaagcctgtcc
agtctcagccaaacagaactggagaagcagcgccagcgccagcgactccgggagttgctg
attcggcagcagatccagcgcaacaccctgcggcaggagaaggagacagctgcagcagct
gcaggagctgtggggcccccgggcagctggggtgctgagcccagcagccctgcctttgag
cagctgagtcgaggccagacccccttcgccgggacccaggacaagagtagccttgtgggg
ctgcccccaagcaagttggggggccccatcctggggccaggggcttttcctggtgatgac
cgactctcccggccacctccaccagccaccccttcttctctggatgtgaatagccggcaa
ctggtgggaggctcccaagccttctatcagcgagcgccctaccctgggtccctgccctta
cagcagcagcagcagcagcagcaactgtggcagcagcagcagcagcaacagcagcaggca
acggcagccacttccatgcgacttgccatgtctactcgctttccgtcaactcctgggcct
gaactgggccgcccagccctgggttcccccttggcgggacttcccactcgcctgcctggc
cccggagagccagtgcctggtccagctggtcctgcccagttcattgagttgcggcacaat
gtccagaagggactaggacctgggggggctccatttcctggtcagggcccccctcagaga
ccccgtttttacccagtaagtgaggactcccaccgaatggctcctgaagggcttcgaggc
ctcgcggtatcaggccttcccccacagaaaccctcagcacccccggcccctgaattgaac
aacagcgtccatccaataccccacaccaaaggtccctccctgcccaccagcttggagctg
gttagccggcccccctcaagcactgagcttggccgtcctcctcctctggccctggaagct
gggaagttaccctgcgaggatcctgagctggacgatgagtttgatgcccacaaggcccta
gaggatgatgaggagcttgctcacctaggcctgggtgtggatgtggccaagggagatgat
gagctgggcaccttggaaaacctggagaccaatgatccccacctggatgacctgctcaac
ggggatgagtttgatctactggcctacactgatcctgagctggacactggggacaaaaag
gacatcttcaatgagcacctaaggctggtggaatcggccaatgaaaaggcagagcgggag
gcccttctgcggggggtggagccagtatccttgggccctgaggaacgccctccacctgct
gctgatgcctctgagccccgtctggcatcagtgcttccagaggtgaagcccaaggtggag
gaaggtgggcgccacccttccccttgccaatttgccattaccacccccaaggtagagccg
gcacctgctaccacttccctaagcctggggctgaagccaggtcagagcgttatgggcagc
cgggacacccggatgggcacaggacccttttccagcagtgggcacacaactgagaagggc
ccctttggggccacgggaggaccaccagctcacctgttgacccccagcccgctgagtggc
ccaggagggtcctctctgctggaaaagtttgagctggagagtgaggccctgaccttgccc
ggtggccatactgcatctggggatgagctggacaagatggagagctcgctggtagccagt
gagttgcccttacttatcgaggacctgttggagcatgagaagaaggagctccagaagaag
cagcagctttccgcacagctgcagcctgttcagcagcagcagcagcagcaacagcaacaa
cagcaacattccttgctgtctgcaccaggccctgcccaggccatgtctttgccacacgag
ggctcttctcccagtttgtctggaccccaacagcagcttgccctaggacttggaggttcg
cgacagccaggcttggcgcaaccactgatgcccacccagccaccagcacatgccctgcag
caacgtctggccccatccatggccatggtatccaatcaagggcatatgctaagtgggcag
catggagggcaggcaggcttggtgccccagcagagctcccagccagtgctggcacagaag
cccatgggtaccatgccaccttctatgtgtatgaaacctcagcagctggccatgcagcag
caactggctaacagcttcttcccggatacagatctggacaaatttgcggcagaagatatc
attgatcccattgcaaaggccaagatggtggctttgaaaggcatcaagaaggtgatggct
cagggcagcattggagtggcacctggtatgaacaggcagcaagtgtccctgctagcccag
aggctctcaggggggcccggcagtgatctgcagaaccatgtggcagctggaagtggccag
gagcggagtgctggtgacccctcccagcctcgtcccaacccgcccacctttgcccaggga
gtgatcaatgaggctgaccagcggcagtatgaggaatggctgtttcatacccaacagctc
ctacagatgcagctgaaggtgctagaggagcagattggtgtgcaccgcaagtctcggaag
gctctgtgcgccaagcagcgcactgccaaaaaggctggtcgtgagttcccggaggctgat
gccgagaagctcaagctggtgacggagcagcagagcaagatccagaaacagctggatcag
gtccggaagcagcagaaggagcacaccaatctcatggcagagtatcggaataagcagcag
cagcagcagcagcagcaacaacagcagcagcagcaacactcagctgtgctggcccttagc
ccttcccagagtccccggctactcaccaagctccctggtcagctgctcccgggccatggg
ctgcagccaccacaggggcctccgggtgggcaagctacaggtcttcgcctgcccccagga
ggcatgacactccctggacagcctggtggccctttcctcaacacctccctggcccaacag
cagcaacagcaacactctggtggagctggggccttggggggcccctcagggggctttttc
ccaggcaacctggctcttcgaggcctaggacccgattcaagacttttacaggaaaggcag
ctgcagctccagcagcagcgcatgcaactagcccagaaactgcaacagcagcagcaacag
cacctcttaggacaggtggcagtccagcagcaacagcagcagagcctgggtgtacaggca
aaccaggctctgggtcccaaaccccaggggcttctgcctcccagcagccgtcagggcctc
ttggtccaacagctgtccccacaaccaccccaggggccccagggcatgctgggccctgcc
caggtagcagtgttgcagcaacagcagcagcagcaacaccctggagccttgggcccccag
ggtcctcacagacaggtgcttctgacccagtcccgggtgctgagttccccccagctggca
cagcagggtcagggcctcatgggacaccggctggtcacagcccagcagcagcagcagcag
caacagcagcaacagcagcaacagcaccaacagcagggatccatggcaggcctttcccat
ctgcagcagggcctgatgccacacggcgggcagcccaaactcagcactcagcccatggcc
gccttgcagcagcagcagctccagcagcagcagcagcagcagcagcagcagctccaacag
caacagcagcagcagcagcaactccaacagcaacagcagcagcagctccaacagcaacag
cagcagcaactgcaacagcagcaattacagcagcagcagcagtttcagcagcagcagcag
caactacagcaacagcagcagcagcaatttcagcagcagcagcaacagcagcagcagcag
cagcaacagcagcaacagcagatgggcctcttgaaccagagtcgaactttactgtctcca
cagcagcagcagccgcagcagccacagcagcaggtgccccttggccccggcatgcccgcc
aagccctcacaacacttttctagccctggagccctgggtaccactgtcctgctgacaggc
aaggagcagagcatggtagagacagctcttcctccagaggccacggaggggccatccaca
catcagggggcaccgctagccctagggactgttcctgagtcggcagccactgaacctggg
gaggtgaagccctcactctccggggactcacagctcctgcttgtccagccgcagacccag
ccacaacccagctctgcgcagctgcagccacctctgaggctcccggggccacagcagcag
caagttaacttgctccacacagccactgtgggaagccatgggcaagcaggcagcggctca
tcctcggaggcctcacccatgccccacctgctggcccaatcctctgttcctttaggggag
cagcctgggaccatgacccagaaccttctgggctcccaacagccccttggactagagcgg
ccggtgcagaataatgccgggccgcagcctgccaaagcaggatctgtcccccagtctgga
ccgggcctgcctgggcctggagtcatgccgacagtgggtcagcttcgagcgcagctccaa
ggagtcctggccaaaaacccccagttgcggcacttgagcccgcagcagcagcagcagcta
caggcactcctcatgcagcggcaactgcagcagagtcaggcagtgcgccaggccccaccc
taccaggaacccggagcccagccctctcccctccagggcctcctgggccgccagccccaa
cttgggggcttccctggatcccaaacaggccccctccaggagctaggggtggggcttcga
cctcagggcccaccccggctccccgccccacaaggagccttagccacaggaccggtcctc
ggccctgtccatcccactcctccaccatccagcccccaagagccaaagagaccttcctca
cagccccccggagccagccccctggtcccatcccagctcccttctgaggcccagctccct
cccacccagccagggaccccaaaaccccaggggccatccttggagctgcctcctgggagg
gtctcacctgctgctgcccagcttgcggatacgttcttcggcaaggggctgggaccttgg
gaccctccagacagcctagtagaagcccagaagccagagcagagcagcctggtacctggg
catctggagcaggtgaatgggcaggcagtgcctgagccaccccatctcagcatcaagcag
gagcctcgggaagagccatgtgccctgggagcccaggcggtgaagagggaggccaacggg
gagccaataggggcaccaggtaccagcaaccacctcctgctggcaggcccccgttcagag
gccgggcatctgctcttgcagaagcttctacgggcaaagaatgtgcaactcagcactggg
cgggggcccgaggggctgcgagctgagatcaacgggcacattgacagcaagctggctggg
ctggagcagaaactacagggtacccccagcaacaaggaggatacagcagcaaggaagcct
gtgacaccgaagcccaagcgggtacagaaggcaagcgacaggttggtgagctcccgaaag
aagctgcggaaggaggacggggtcagggccagcgaggccttgctgaaacagctgaaacag
gagctgtccctgctgcccctaacggagcctaccatcaccgccaattttagcctctttgct
cccttcggcagtggctgcccagtcaacgggcagtgccagctgaggggggcctttggaagt
ggggcactgcccactggccctgactactattcccagctgcttaccaagaataacctgagt
aacccgccgacaccaccctcgtcgctgccccccaccccacccccatcggtgcagcagaag
atggtgaatggcgtcactccatccgaagagctgggggagcaccccaaggatgctgcctct
gcccgggatactgaagggacgctgagggatgcttcagaggtgaagagtctagacctgctg
gccgccttgcctacaccccctcacaatcagactgaggatgtcaggatggaaagtgacgag
gacagcgattctcctgatagcattgtgccagcttcgtcccccgaaagcatcctaggggag
gaggcacctcgtttccctcagctgggctcaggccggtgggagcaggaagaccgggctctc
tcccctgttatccccataattcctcgggccagtatcccagtcttcccagataccaaacct
tatggggccctggacctggagacctctggaaagctgcctgccacaacttgggaaaagggc
aaaggaagtgaggtgtcggtcatgctgacggtctctgctgctgcggccaagaacctgaat
ggtgtgatggtggcagtggcagagctgctaagcatgaagatccccaactcctatgaggtg
ctgttcccagagagccctgcccgggcaggcattgagcctaagaagggggaagctgagggc
cctggagggaaagaaaagggtctgggaggcaagagcccggaagctggccctgattggctg
aaacagtttgatgcagtgttgcctggctataccctcaagagccagctagacatcctgagc
ctcctgaaacaggagagccctgccccagagccccccacccaacacagctacacctacaac
gtctccaatctggatgtgcgacagctctcggccccacctcctgaggaaccctccccgccc
ccgtcccccttggcaccctctcctgccagcccccctgctgagcccctggttgaactcccg
gctgaaccctcagctgagccaccagtcccatcgcctctgccactggcctcgtcccctgag
tcagcccgacccaagcctcgagcccggccccctgaagaaggtgaagattcccggccccct
cgcctcaagaagtggaaaggggtgcgctggaagcggctgcggctgctgctgaccatccag
aagggcagtgggcggcaggaggacgagcgggaagtggcggagtttatggaacagctcggc
acagccctgcgacccgacaaggtgcctcgtgatatgcggcgctgctgcttctgtcatgag
gagggtgacggggccactgatgggccggcgcgcctgctgaacctggacctggacctgtgg
gtgcacctcaactgtgccctgtggtccacagaggtgtacgagacccagggtggggcgctg
atgaacgttgaggtcgccctgcaccgagggctgctcaccaagtgctccctgtgccagcgc
accggcgccaccagcagctgcaatcgaatgcgttgccccaacgtctaccattttgcctgc
gccatccgcgccaagtgcatgttcttcaaggacaagaccatgctgtgtccaatgcataag
atcaaggggccctgtgaacaggagctgagctcttttgctgtcttccggcgggtctacatt
gagcgggatgaggtgaagcaaatcgccagcatcatccagcggggagagcggctacacatg
ttccgcgtggggggccttgtgttccacgccatcggacagctgctccctcatcagatggct
gacttccacagtgccactgccctctatcccgttggctatgaggccacgcgcatctattgg
agcctccgcaccaacaaccgccgctgctgctaccgctgctccatcggcgagaacaacgga
aggccagagttcgtcatcaaagtcatggagcagggcctggaggacctggtcttcacggat
gcctccccccaggctgtgtggaaccgcatcatcgagcctgtggccgccatgagaaaagag
gccgacatgctgcggctcttccccgagtacctgaagggcgaggagctcttcgggctgacg
gtgcacgccgtgctgcgcatagctgaatcactgcctggagtggagagctgtcaaaactat
ttattccgctacggacgccaccccctgatggagctgccactcatgatcaatcccactggt
tgtgcccgatcggagcctaaaatcctcacacactacaaacggcctcacaccctgaacagc
accagcatgtccaaggcatatcagagcaccttcacaggcgagaccaacaccccatacagt
aagcagtttgtgcactccaagtcatcacagtaccggcgcctgcgcactgagtggaagaac
aacgtgtacctggctcgctcccgtatccagggcctggggctctatgccgccaaggaccta
gaaaagcacacaatggtcatcgaatatattggcaccatcattcgcaatgaggtggccaac
cggcgggagaaaatctatgaggagcagaatcgcggcatctacatgttccgaataaacaac
gaacatgtaattgatgctacgttgaccggaggccctgccaggtacattaaccattcctgt
gcccctaactgtgtggcggaagttgtgacatttgacaaggaggataaaatcatcatcatc
tccagccggcgaatccccaaaggagaggagctgacctatgactatcagtttgactttgag
gacgatcagcacaagattccctgccactgtggagcctggaactgtcggaaatggatgaac
taa
DBGET
integrated database retrieval system
