Canis lupus familiaris (dog): 491166
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Entry
491166 CDS
T01007
Symbol
SLC46A1
Name
(RefSeq) proton-coupled folate transporter
KO
K14613
MFS transporter, PCFT/HCP family, solute carrier family 46 (folate transporter), member 1
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa01523
Antifolate resistance
cfa04977
Vitamin digestion and absorption
cfa04978
Mineral absorption
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09150 Organismal Systems
09154 Digestive system
04977 Vitamin digestion and absorption
491166 (SLC46A1)
04978 Mineral absorption
491166 (SLC46A1)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
491166 (SLC46A1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
cfa02000
]
491166 (SLC46A1)
Transporters [BR:
cfa02000
]
Solute carrier family (SLC)
SLC46: Folate transporter
491166 (SLC46A1)
Major facilitator superfamily (MFS)
Organic acid transporters
Proton coupled folate transporter/heme carrier protein (PCFT/HCP) family [TC:
2.A.1.50
]
491166 (SLC46A1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
MFS_1
Sugar_tr
Motif
Other DBs
NCBI-GeneID:
491166
NCBI-ProteinID:
XP_003435354
Ensembl:
ENSCAFG00000018682
VGNC:
46426
UniProt:
A0A8C0Z2T9
A0A8I3N1L5
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Position
9:complement(41795562..41807087)
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AA seq
459 aa
AA seq
DB search
MEGRPSPPGEARVRRSAAALCRGPVEPLVFLANFALVLQGPLTTQYLWHRFSAELGYNGT
RDRGSCSNHSADPVMKEVETLTSHWTLYMNLGGFLVGLFSSTLLGAWSDCVGRRPLLVLA
SLGLLLQAVVSIFVVQLQLHVGYFVLGRILCALLGDFNGLLAASFASVADVSSNRSRTLR
MALLEACIGVAGMLASLLGGHWLRAQGYANPFWLALAVLIVMTFYAALCFGETVKEPTPA
RLFTLRHHRSIVWLYMTPAPEKSRKHLALYSLAIFMVITVHFGAQDILTLYELSKPLCWD
SRLVGYGSAAQHLPYLTSLVGLRLLQHCLADTWVAEIGLAFNILGMVVFAFATITPLMFT
GYGLLFLSLVTTPIIRAKLSKLVGKSEQGALFSSVACINSLAMLMASGIFNSLYPATLNF
MKGFPFLLGAGLLFIPAILIGVLEKANPHPEFQQFPQSP
NT seq
1380 nt
NT seq
+upstream
nt +downstream
nt
atggaggggcgcccgagccccccgggcgaggcccgcgtccgccgctcggctgccgcgctg
tgccgcggccccgtggagcccctcgtcttcctggccaacttcgctttggtcctgcagggc
ccgctcaccacgcaatacttgtggcaccgcttcagtgccgagctcggctacaatggcacc
cgcgacaggggcagctgcagcaaccacagcgccgacccggtcatgaaggaagtggagacc
cttacctcccactggaccctctacatgaacctgggcggcttcctggtggggctcttctca
tccaccctgctgggtgcctggagtgactgcgtgggccgccgccccctcctggtgctggcc
tccctgggcctgttgctacaggcagtggtgtccatcttcgtcgtccagctgcagctccac
gtcggctacttcgtgctgggccgcatcctttgtgctctccttggggacttcaatggcctt
ctggcagcaagctttgcctctgtggcagatgtcagctccaaccgcagccgcaccttgcga
atggccctgctggaagcatgcatcggggtggcagggatgctggcaagcctcctggggggc
cactggctccgggcccagggttatgccaatcccttctggctggccttggccgtgttgata
gtcatgactttctatgcagcattatgctttggtgagacagtgaaggagccgacacctgcc
cggctcttcacgctccgtcaccaccgatccattgtctggctatacatgactccggcccca
gagaagtccaggaagcatttagccctgtattcactggccatcttcatggtaatcactgtg
cactttggggctcaggacatcctgaccctctatgagctgagcaaacccctctgctgggac
tccaggctggtcggctatggttcagcagctcagcacctcccgtacctcaccagcctagtg
ggcctgcggcttttgcagcactgcctggctgatacctgggtggccgagattggcctggcc
ttcaacattctggggatggtggtctttgcattcgctaccatcacacctctcatgtttaca
gggtatgggcttctgttcctgtcattagtcactacacccatcatccgggccaagctctcc
aagctggtgggcaagtcagagcagggtgctcttttttcttcggtggcctgcatcaatagc
ttggccatgctgatggcttctggcatcttcaactcactctacccagccaccttgaacttc
atgaaggggttccccttcctcctgggagctggcctcctcttcatcccggccattctgatt
ggggtgctggaaaaggctaatcctcatcccgaattccagcagtttcctcagagcccctga
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