KEGG   Camelus ferus (Wild Bactrian camel): 102509744
Entry
102509744         CDS       T02979                                 

Gene name
TGFBR2
Definition
(RefSeq) TGF-beta receptor type-2 isoform X1
  KO
K04388  TGF-beta receptor type-2 [EC:2.7.11.30]
Organism
cfr  Camelus ferus (Wild Bactrian camel)
Pathway
cfr04010  MAPK signaling pathway
cfr04060  Cytokine-cytokine receptor interaction
cfr04068  FoxO signaling pathway
cfr04144  Endocytosis
cfr04218  Cellular senescence
cfr04350  TGF-beta signaling pathway
cfr04380  Osteoclast differentiation
cfr04390  Hippo signaling pathway
cfr04520  Adherens junction
cfr04659  Th17 cell differentiation
cfr04926  Relaxin signaling pathway
cfr04933  AGE-RAGE signaling pathway in diabetic complications
cfr05142  Chagas disease
cfr05161  Hepatitis B
cfr05166  Human T-cell leukemia virus 1 infection
cfr05200  Pathways in cancer
cfr05202  Transcriptional misregulation in cancer
cfr05210  Colorectal cancer
cfr05212  Pancreatic cancer
cfr05220  Chronic myeloid leukemia
cfr05225  Hepatocellular carcinoma
cfr05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:cfr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102509744 (TGFBR2)
   04350 TGF-beta signaling pathway
    102509744 (TGFBR2)
   04390 Hippo signaling pathway
    102509744 (TGFBR2)
   04068 FoxO signaling pathway
    102509744 (TGFBR2)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    102509744 (TGFBR2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    102509744 (TGFBR2)
  09143 Cell growth and death
   04218 Cellular senescence
    102509744 (TGFBR2)
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    102509744 (TGFBR2)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    102509744 (TGFBR2)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    102509744 (TGFBR2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    102509744 (TGFBR2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102509744 (TGFBR2)
   05202 Transcriptional misregulation in cancer
    102509744 (TGFBR2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    102509744 (TGFBR2)
   05212 Pancreatic cancer
    102509744 (TGFBR2)
   05225 Hepatocellular carcinoma
    102509744 (TGFBR2)
   05226 Gastric cancer
    102509744 (TGFBR2)
   05220 Chronic myeloid leukemia
    102509744 (TGFBR2)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    102509744 (TGFBR2)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    102509744 (TGFBR2)
   05161 Hepatitis B
    102509744 (TGFBR2)
  09174 Infectious disease: parasitic
   05142 Chagas disease
    102509744 (TGFBR2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cfr01001]
    102509744 (TGFBR2)
Enzymes [BR:cfr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.30  receptor protein serine/threonine kinase
     102509744 (TGFBR2)
Protein kinases [BR:cfr01001]
 Receptor serine/threonine kinases (RSTK): TKL group
  TGFBR2 family [OT]
   102509744 (TGFBR2)
SSDB
Motif
Pfam: ecTbetaR2 PK_Tyr_Ser-Thr Pkinase Pkinase_fungal APH
Other DBs
NCBI-GeneID: 102509744
NCBI-ProteinID: XP_032315265
LinkDB
Position
17
AA seq 567 aa
MGRGLLGGLWLLHVVLWTRIASTIPPHVPKSVNSDMLVTDNNGAVKLPQLCKFCDVRAST
CDNQKSCLSNCSITAICEKPHEVCVAVWRKNDENITLETVCHDPKIAYHGFVLDDAASPK
CIMKEKKGSGETFFMCSCSSDECNDHIIFSEEYATNNPDLLLVIFQVTGVSLLPPLGIAV
AVIVTFYCYRVHRQQKLSSSWDSGKPRKLMEFSEHLAIILEDDRSDISSTCANNINHNTE
LLPIELDTLVGKGRFAEVYKAKLRQNTSEQFETVAVKIFPYEEYASWKTEKDIFSDINLK
HENILQFLTAEERKTELGKQYWLITAFHAKGNLQEYLTRHVVSWEDLRKLGGSLARGIAH
LHSDRTLCGRPKMPIVHRDLKSSNILVKGDLTCCLCDFGLSLRLDPTLSVDDLANSGQVG
TARYMAPEVLESRMNLENVESFKQTDVYSMALVLWEMTSRCNAVGEVKDYEPPFGSKVRE
HPCVESMKDNVLRDRERPEIPSSWLSHQGIQTVCETLAECWDHDPEARLTAQCVAERFSE
LEHLDRLSGRSSSEEKIPEDGSLNTTK
NT seq 1704 nt   +upstreamnt  +downstreamnt
atgggccgggggctgctcgggggcctgtggctgctgcacgtcgtcctgtggacgcgcatc
gccagcaccatcccgccgcacgttcccaagtcggtgaacagtgacatgctggtcacggac
aataacggcgccgtcaagcttccgcaactgtgtaagttctgcgacgtgcgcgcctccacc
tgtgacaaccagaaatcctgcctgagcaactgcagcatcacggctatctgcgagaagccg
cacgaagtctgcgtggccgtctggagaaagaatgatgagaacatcacactagagacggtt
tgccacgaccccaagatcgcttaccatggctttgttctcgacgacgcggcttctcccaag
tgcatcatgaaggaaaagaaggggtcaggagagactttcttcatgtgttcctgtagctcc
gatgagtgcaacgaccacatcatcttctctgaagagtacgccaccaacaacccagacttg
ctgctagtcatattccaggtgacaggcgtcagcctcctgccgccgctgggcatcgccgtc
gccgtcatcgtcaccttctactgctaccgtgttcaccggcagcagaagctgagctcgtcc
tgggactcggggaagccgcggaagctgatggagttcagcgagcacctggccatcatcctg
gaagacgaccgctccgacatcagctccacctgcgccaacaacatcaaccacaacacggag
ctgctgcccatcgagctggacaccctggtgggcaagggccgcttcgccgaggtctacaag
gccaagctgcggcagaacacgtctgagcagttcgagaccgtggccgtcaagatcttcccc
tacgaggagtatgcctcctggaagacggagaaggacatcttctcggacatcaacctcaag
cacgagaacatcctccagttcctgacagccgaggagcgcaagacggagctgggcaagcag
tactggctgatcaccgccttccacgccaagggcaacctgcaggagtacctcacccggcac
gtcgtcagctgggaggacctgcgcaagctgggcggctcgctggcccgcggcatcgcgcac
ctgcacagcgaccgcaccctgtgcggccggcccaagatgcccatcgtgcacagggacctc
aagagctccaacatcctggtcaagggcgacctcacctgctgcctctgcgacttcgggctc
tccctgcgtctggacccgactctgtctgtggacgacctggccaacagtgggcaggtggga
actgcacgatacatggccccagaagtcctcgagtccaggatgaatttggagaatgttgag
tccttcaagcagacagatgtctactccatggccctggtgctctgggagatgacgtcccgc
tgcaacgcggtgggagaagtgaaagattacgagcctccgttcggttccaaggtgcgggag
cacccctgtgtggaaagcatgaaggacaatgtgctgagagaccgggaacggccggagatc
cccagctcctggctcagccaccagggcatccagacggtgtgtgagacgctggccgagtgc
tgggaccacgaccccgaggcccggctcactgcgcagtgcgtggccgagcgcttcagcgag
ctggagcatctggacagactctcggggaggagcagctcggaggagaagattcccgaagat
ggctccctgaacactaccaaatag

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