KEGG   Camelus ferus (Wild Bactrian camel): 102515306
Entry
102515306         CDS       T02979                                 

Gene name
GRB2
Definition
(RefSeq) growth factor receptor-bound protein 2
  KO
K04364  growth factor receptor-bound protein 2
Organism
cfr  Camelus ferus (Wild Bactrian camel)
Pathway
cfr01521  EGFR tyrosine kinase inhibitor resistance
cfr01522  Endocrine resistance
cfr04010  MAPK signaling pathway
cfr04012  ErbB signaling pathway
cfr04014  Ras signaling pathway
cfr04062  Chemokine signaling pathway
cfr04068  FoxO signaling pathway
cfr04072  Phospholipase D signaling pathway
cfr04150  mTOR signaling pathway
cfr04151  PI3K-Akt signaling pathway
cfr04380  Osteoclast differentiation
cfr04510  Focal adhesion
cfr04540  Gap junction
cfr04550  Signaling pathways regulating pluripotency of stem cells
cfr04630  JAK-STAT signaling pathway
cfr04650  Natural killer cell mediated cytotoxicity
cfr04660  T cell receptor signaling pathway
cfr04662  B cell receptor signaling pathway
cfr04664  Fc epsilon RI signaling pathway
cfr04714  Thermogenesis
cfr04722  Neurotrophin signaling pathway
cfr04910  Insulin signaling pathway
cfr04912  GnRH signaling pathway
cfr04915  Estrogen signaling pathway
cfr04917  Prolactin signaling pathway
cfr04926  Relaxin signaling pathway
cfr04935  Growth hormone synthesis, secretion and action
cfr05034  Alcoholism
cfr05160  Hepatitis C
cfr05161  Hepatitis B
cfr05163  Human cytomegalovirus infection
cfr05165  Human papillomavirus infection
cfr05200  Pathways in cancer
cfr05203  Viral carcinogenesis
cfr05205  Proteoglycans in cancer
cfr05206  MicroRNAs in cancer
cfr05210  Colorectal cancer
cfr05211  Renal cell carcinoma
cfr05213  Endometrial cancer
cfr05214  Glioma
cfr05215  Prostate cancer
cfr05220  Chronic myeloid leukemia
cfr05221  Acute myeloid leukemia
cfr05223  Non-small cell lung cancer
cfr05224  Breast cancer
cfr05225  Hepatocellular carcinoma
cfr05226  Gastric cancer
cfr05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:cfr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102515306 (GRB2)
   04012 ErbB signaling pathway
    102515306 (GRB2)
   04014 Ras signaling pathway
    102515306 (GRB2)
   04630 JAK-STAT signaling pathway
    102515306 (GRB2)
   04068 FoxO signaling pathway
    102515306 (GRB2)
   04072 Phospholipase D signaling pathway
    102515306 (GRB2)
   04151 PI3K-Akt signaling pathway
    102515306 (GRB2)
   04150 mTOR signaling pathway
    102515306 (GRB2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    102515306 (GRB2)
   04540 Gap junction
    102515306 (GRB2)
   04550 Signaling pathways regulating pluripotency of stem cells
    102515306 (GRB2)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    102515306 (GRB2)
   04660 T cell receptor signaling pathway
    102515306 (GRB2)
   04662 B cell receptor signaling pathway
    102515306 (GRB2)
   04664 Fc epsilon RI signaling pathway
    102515306 (GRB2)
   04062 Chemokine signaling pathway
    102515306 (GRB2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    102515306 (GRB2)
   04912 GnRH signaling pathway
    102515306 (GRB2)
   04915 Estrogen signaling pathway
    102515306 (GRB2)
   04917 Prolactin signaling pathway
    102515306 (GRB2)
   04926 Relaxin signaling pathway
    102515306 (GRB2)
   04935 Growth hormone synthesis, secretion and action
    102515306 (GRB2)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    102515306 (GRB2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    102515306 (GRB2)
  09159 Environmental adaptation
   04714 Thermogenesis
    102515306 (GRB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102515306 (GRB2)
   05206 MicroRNAs in cancer
    102515306 (GRB2)
   05205 Proteoglycans in cancer
    102515306 (GRB2)
   05203 Viral carcinogenesis
    102515306 (GRB2)
   05231 Choline metabolism in cancer
    102515306 (GRB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    102515306 (GRB2)
   05225 Hepatocellular carcinoma
    102515306 (GRB2)
   05226 Gastric cancer
    102515306 (GRB2)
   05214 Glioma
    102515306 (GRB2)
   05221 Acute myeloid leukemia
    102515306 (GRB2)
   05220 Chronic myeloid leukemia
    102515306 (GRB2)
   05211 Renal cell carcinoma
    102515306 (GRB2)
   05215 Prostate cancer
    102515306 (GRB2)
   05213 Endometrial cancer
    102515306 (GRB2)
   05224 Breast cancer
    102515306 (GRB2)
   05223 Non-small cell lung cancer
    102515306 (GRB2)
  09165 Substance dependence
   05034 Alcoholism
    102515306 (GRB2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    102515306 (GRB2)
   05160 Hepatitis C
    102515306 (GRB2)
   05163 Human cytomegalovirus infection
    102515306 (GRB2)
   05165 Human papillomavirus infection
    102515306 (GRB2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    102515306 (GRB2)
   01522 Endocrine resistance
    102515306 (GRB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:cfr04131]
    102515306 (GRB2)
  09183 Protein families: signaling and cellular processes
   04990 Domain-containing proteins not elsewhere classified [BR:cfr04990]
    102515306 (GRB2)
Membrane trafficking [BR:cfr04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Receptor tyrosine kinase (RTK) adaptor proteins
    102515306 (GRB2)
Domain-containing proteins not elsewhere classified [BR:cfr04990]
 Src homology (SH) domain-containing proteins
  Signal transducing adaptor proteins
   102515306 (GRB2)
SSDB
Motif
Pfam: SH3_1 SH3_9 SH3_2 SH2 SH3_10 SH2_2 SH3_3 DUF5093 hSH3 SH3_4
Other DBs
NCBI-GeneID: 102515306
NCBI-ProteinID: XP_032312737
LinkDB
Position
16
AA seq 217 aa
MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPW
FFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFL
WVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRG
DFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV
NT seq 654 nt   +upstreamnt  +downstreamnt
atggaagccatcgccaaatatgacttcaaagctaccgcagacgacgagctgagcttcaaa
aggggggacatcctcaaggttttgaatgaagaatgtgaccagaactggtacaaggcagag
ctcaatgggaaagacggcttcatccccaagaattacatagaaatgaaaccacatccgtgg
ttttttggcaaaatccccagagccaaggcagaagaaatgcttagcaaacagcggcacgat
ggggcttttctgatccgagagagtgagagtgcgcctggggatttctccctctctgtcaag
tttggaaatgacgtgcagcacttcaaggtgctccgagacggagctggaaagtatttcctc
tgggtggtgaagttcaattctttgaatgagctggtagattatcacagatctacatccgtc
tctagaaaccagcagattttcctccgggacatagagcaggtgccacagcagccaacatac
gtccaagccctctttgacttcgatccccaggaggatggagagctgggattccgccgggga
gactttatccacgtcatggataactcagaccccaactggtggaaaggggcttgccacggg
cagaccggcatgtttccgcgcaattacgtcacccccgtgaaccggaacgtctaa

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