KEGG   Camelus ferus (Wild Bactrian camel): 102522485
Entry
102522485         CDS       T02979                                 

Gene name
TGFBR1
Definition
(RefSeq) TGF-beta receptor type-1 isoform X1
  KO
K04674  TGF-beta receptor type-1 [EC:2.7.11.30]
Organism
cfr  Camelus ferus (Wild Bactrian camel)
Pathway
cfr04010  MAPK signaling pathway
cfr04060  Cytokine-cytokine receptor interaction
cfr04068  FoxO signaling pathway
cfr04144  Endocytosis
cfr04218  Cellular senescence
cfr04350  TGF-beta signaling pathway
cfr04371  Apelin signaling pathway
cfr04380  Osteoclast differentiation
cfr04390  Hippo signaling pathway
cfr04520  Adherens junction
cfr04659  Th17 cell differentiation
cfr04926  Relaxin signaling pathway
cfr04933  AGE-RAGE signaling pathway in diabetic complications
cfr05142  Chagas disease
cfr05161  Hepatitis B
cfr05166  Human T-cell leukemia virus 1 infection
cfr05200  Pathways in cancer
cfr05210  Colorectal cancer
cfr05212  Pancreatic cancer
cfr05220  Chronic myeloid leukemia
cfr05225  Hepatocellular carcinoma
cfr05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:cfr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102522485 (TGFBR1)
   04350 TGF-beta signaling pathway
    102522485 (TGFBR1)
   04390 Hippo signaling pathway
    102522485 (TGFBR1)
   04371 Apelin signaling pathway
    102522485 (TGFBR1)
   04068 FoxO signaling pathway
    102522485 (TGFBR1)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    102522485 (TGFBR1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    102522485 (TGFBR1)
  09143 Cell growth and death
   04218 Cellular senescence
    102522485 (TGFBR1)
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    102522485 (TGFBR1)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    102522485 (TGFBR1)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    102522485 (TGFBR1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    102522485 (TGFBR1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102522485 (TGFBR1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    102522485 (TGFBR1)
   05212 Pancreatic cancer
    102522485 (TGFBR1)
   05225 Hepatocellular carcinoma
    102522485 (TGFBR1)
   05226 Gastric cancer
    102522485 (TGFBR1)
   05220 Chronic myeloid leukemia
    102522485 (TGFBR1)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    102522485 (TGFBR1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    102522485 (TGFBR1)
   05161 Hepatitis B
    102522485 (TGFBR1)
  09174 Infectious disease: parasitic
   05142 Chagas disease
    102522485 (TGFBR1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cfr01001]
    102522485 (TGFBR1)
Enzymes [BR:cfr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.30  receptor protein serine/threonine kinase
     102522485 (TGFBR1)
Protein kinases [BR:cfr01001]
 Receptor serine/threonine kinases (RSTK): TKL group
  TGFBR1 family [OT]
   102522485 (TGFBR1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr TGF_beta_GS Activin_recp Pkinase_fungal APH FTA2
Other DBs
NCBI-GeneID: 102522485
NCBI-ProteinID: XP_032333958
LinkDB
Position
4
AA seq 503 aa
MEAAAAAPRPRLLLLVLAAATTLVPETTALQCFCHLCTKDNFTCVTDGLCFVSVTETTDK
VIHNSMCIAEIDLIPRDRPFVCAPSSKTGSVTTTYCCNQDHCNKIELPTVGPFPGKPSSG
LGPVELAAVIAGPVCFVCISLMLMVYICHNRTVIHHRVPNEEDPSLDRPFISEGTTLKDL
IYDMTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREER
SWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVE
GMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDS
ATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSVGGI
HEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGA
ARLTALRIKKTLSQLSQQEGIKM
NT seq 1512 nt   +upstreamnt  +downstreamnt
atggaggcggcggccgctgctccacgtcccaggctgctcctcctcgtgctggcggcggcg
acgacgctggtcccggagacgacggcattacagtgtttctgccacctttgtacaaaagac
aattttacttgtgtcacagatgggctctgctttgtctctgtcacagagaccacagacaaa
gttatacacaatagcatgtgtatagctgagatcgacctaattccgcgagacaggccattt
gtatgtgcgccatcttcaaaaactgggtctgttactacaacatattgctgcaatcaggac
cactgcaataaaatagaactcccaactgttggcccttttccaggaaagccatcatctggc
cttggtcctgttgagttggcagctgtcattgctggaccagtctgcttcgtctgcatctca
ctcatgttgatggtctatatctgccataaccgcactgtcattcaccatcgagtgccaaat
gaagaggatccttccttagatcgccctttcatttcagagggtactacgttaaaagattta
atttatgatatgactacatcgggttctggatcaggtttaccgttgcttgttcagagaaca
attgcaagaactattgtgttacaagaaagtattggcaaaggtcgatttggagaagtttgg
cgaggaaaatggagaggcgaagaagtcgctgttaaaatattctcctctagagaagaacgt
tcatggttccgtgaggcagagatctatcagactgtgatgttacgtcatgaaaacatcttg
ggatttatagcagcagataataaagacaatggtacatggactcagctctggttggtgtca
gattatcatgagcatggatccctttttgattatttgaacagatacacagttactgtggaa
ggaatgataaaactcgctctgtccacagcaagtggacttgcccatcttcacatggaaatt
gttggtacccaaggaaaaccagccattgctcatagagatttgaaatcaaagaatatcttg
gtaaagaagaatggaacttgctgtattgcggacttgggactggcagtaagacatgattcg
gccactgatacaattgatattgctccaaaccacagagtgggaacaaaaaggtatatggcc
cctgaagttcttgatgattccataaatatgaaacactttgaatccttcaaacgtgctgac
atctatgcaatgggcttagtattctgggaaatagctcgacgatgttccgttggtggaatt
catgaagattaccagctgccttactatgatcttgtaccttctgatccatcagttgaagaa
atgagaaaagttgtttgtgaacagaagttaaggccaaatattccaaacagatggcagagc
tgtgaagccttgagagtgatggcaaaaattatgagagaatgttggtatgccaatggggca
gctaggcttacagctttgcggattaagaaaacattgtcgcagctcagtcaacaggaaggc
atcaaaatgtaa

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