Camelus ferus (Wild Bactrian camel): 102524338
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Entry
102524338 CDS
T02979
Gene name
IGF1R
Definition
(RefSeq) insulin-like growth factor 1 receptor isoform X1
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
cfr
Camelus ferus (Wild Bactrian camel)
Pathway
cfr01521
EGFR tyrosine kinase inhibitor resistance
cfr01522
Endocrine resistance
cfr04010
MAPK signaling pathway
cfr04014
Ras signaling pathway
cfr04015
Rap1 signaling pathway
cfr04066
HIF-1 signaling pathway
cfr04068
FoxO signaling pathway
cfr04114
Oocyte meiosis
cfr04140
Autophagy - animal
cfr04144
Endocytosis
cfr04150
mTOR signaling pathway
cfr04151
PI3K-Akt signaling pathway
cfr04152
AMPK signaling pathway
cfr04211
Longevity regulating pathway
cfr04213
Longevity regulating pathway - multiple species
cfr04510
Focal adhesion
cfr04520
Adherens junction
cfr04550
Signaling pathways regulating pluripotency of stem cells
cfr04730
Long-term depression
cfr04913
Ovarian steroidogenesis
cfr04914
Progesterone-mediated oocyte maturation
cfr05200
Pathways in cancer
cfr05202
Transcriptional misregulation in cancer
cfr05205
Proteoglycans in cancer
cfr05214
Glioma
cfr05215
Prostate cancer
cfr05218
Melanoma
cfr05224
Breast cancer
cfr05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
cfr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102524338 (IGF1R)
04014 Ras signaling pathway
102524338 (IGF1R)
04015 Rap1 signaling pathway
102524338 (IGF1R)
04066 HIF-1 signaling pathway
102524338 (IGF1R)
04068 FoxO signaling pathway
102524338 (IGF1R)
04151 PI3K-Akt signaling pathway
102524338 (IGF1R)
04152 AMPK signaling pathway
102524338 (IGF1R)
04150 mTOR signaling pathway
102524338 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
102524338 (IGF1R)
04140 Autophagy - animal
102524338 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
102524338 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
102524338 (IGF1R)
04520 Adherens junction
102524338 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
102524338 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
102524338 (IGF1R)
04914 Progesterone-mediated oocyte maturation
102524338 (IGF1R)
09156 Nervous system
04730 Long-term depression
102524338 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
102524338 (IGF1R)
04213 Longevity regulating pathway - multiple species
102524338 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102524338 (IGF1R)
05202 Transcriptional misregulation in cancer
102524338 (IGF1R)
05205 Proteoglycans in cancer
102524338 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
102524338 (IGF1R)
05214 Glioma
102524338 (IGF1R)
05218 Melanoma
102524338 (IGF1R)
05215 Prostate cancer
102524338 (IGF1R)
05224 Breast cancer
102524338 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
102524338 (IGF1R)
01522 Endocrine resistance
102524338 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
cfr01001
]
102524338 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
cfr04090
]
102524338 (IGF1R)
Enzymes [BR:
cfr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
102524338 (IGF1R)
Protein kinases [BR:
cfr01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
102524338 (IGF1R)
CD molecules [BR:
cfr04090
]
Proteins
102524338 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Pkinase
Furin-like
fn3
Kinase-like
Insulin_TMD
DUF4476
Motif
Other DBs
NCBI-GeneID:
102524338
NCBI-ProteinID:
XP_032324756
LinkDB
All DBs
Position
27
AA seq
1369 aa
AA seq
DB search
MKSGSGGGSPTSLWGLLFFSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGTMEEKPLCEKTTINNEYNYRCWTTNRCQKMCPSACGKRACTENHECCHPECLGSCS
APDDDAACVACRHYYYAGVCVPSCPPNTYRFEGWRCVDRDFCANIPSAESSDSEGFVIHD
GECMQECPSGFIRNGTQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNL
LINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRQILGEEQLEGNYSF
YVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTR
NNGERASCESDVLHFTSTTTWKNRIIVTWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDG
QDACGSNSWNMVDVDLPPNKDIEPGILLQGLKPWTQYAVYVKAVTLTMVENDHIRGAKSE
ILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDSYLYRH
NYCSKGEDKIPIRKYADGTIDVEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEY
RKVFENFLHNAIFVPRPERKRREVMQVANTTTSSRSRNTTVVDTYNITDPEELETEYPFF
ESRVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPV
TWEPRPENSIFLKWPEPENPNGLILMYEIKYGSLVEDQRECVSRQDYRKYGGAKLNRLNP
GNYTARIQATSLSGNGSWTDPVFFYVQAKTTYENFIHLIIALPVAVLLIVGGLVIMLYVF
HRKRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVA
KGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVI
MELMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAA
RNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSF
GVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPS
FLEIISSIKDEMEPGFREVSFYYSEENKPPEPEELDLEPENMESVPLDPSASSSSLPLPE
RHSGHKAENGPGPGVLVLRASFDERQPYAHMNGGRKNERALPLPQSSTC
NT seq
4110 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctggctccggaggagggtccccgacctcgctgtgggggctcctgtttttctcc
gccgcgctctcgctgtggccgacgagtggagaaatctgcgggccaggcatcgacatccgc
aatgactaccagcagctgaagcgcctggagaactgcacggtgatcgagggctacctccac
atcctgctcatctccaaggccgaggactaccgcagctaccgcttccccaagctcacggtc
atcaccgagtacctgctgctgttccgcgtggccggcctggagagcctcggcgacctcttc
cccaacctcacggtcatccgtggctggaagctcttctacaactacgccctggtcatcttc
gagatgaccaacctcaaggacatcgggctgtacaacctgaggaacatcacccggggggcc
atcaggatcgagaagaatgccgacctctgctacctctccacggtggactggtccttgatc
ctggacgccgtgtccaataactacatcgtggggaacaagcccccgaaggagtgcggggac
ctgtgtccagggacgatggaggagaagccgttgtgtgagaagaccaccatcaacaatgag
tacaactaccgctgctggaccacgaaccgctgccagaaaatgtgcccgagcgcgtgcggg
aagcgggcgtgcacggagaaccacgagtgctgccaccccgagtgcctgggcagctgcagc
gcgcccgacgacgacgcggcctgcgtggcctgccgccactactactacgccggcgtctgc
gtgcccagctgcccgcccaacacctaccgcttcgagggctggcgctgcgtggaccgcgac
ttctgcgccaacatccccagcgccgagagcagcgactccgagggcttcgtgatccacgac
ggcgagtgcatgcaggagtgcccctcgggcttcatccgcaacggcactcagagcatgtac
tgcatcccttgcgaaggcccttgccccaaagtctgtgaggaagaaaagaaaacaaagacc
attgattcagtcacttctgctcaaatgctccaaggatgcaccatcttcaagggcaatctg
ctcattaatatccgacgtggcaacaacatcgcttcggaactggagaacttcatggggctc
attgaggtggtgacgggctacgtgaagatccgtcactcccacgccttggtgtccttgtcc
ttcctgaagaacctgcgccagatcctaggagaggagcagctcgaggggaattactccttc
tacgtcctcgacaaccagaacttgcagcagctgtgggactgggaccaccgcaacctgact
atcaaagctgggaaaatgtactttgctttcaatcccaaattgtgtgtctccgaaatttac
cgcatggaggaggtgaccgggactaaagggcgccagagcaaaggggacataaacaccagg
aacaacggagagcgagcctcctgcgaaagcgatgtcctgcacttcacctccaccaccacc
tggaagaaccgcatcatcgtcacctggcaccggtaccggccccctgactacagggacctc
atcagcttcaccgtctactacaaggaggcaccctttaaaaacgtcacggagtatgacggg
caggatgcctgtggctccaacagctggaacatggtggatgtggacctccctcccaacaag
gacatcgagcctggcatcttactgcaggggctgaagccctggacgcagtatgctgtctac
gtcaaggccgtgaccctcaccatggtggagaacgaccacatccgtggggccaaaagcgag
atcttgtacattcgcaccaacgcttcagttccttccattcccctggatgttctctcagca
tcaaactcctcttctcagctgattgtgaagtggaacccgccctctctgcccaacggcaac
ctgagttactacatcgtgcggtggcagcgccagcctcaggacagctacctttaccggcac
aactactgctccaaaggtgaggacaaaatccccatcaggaagtatgctgatggcaccatc
gacgtcgaggaggtgacggagaatcccaagaccgaagtgtgtggtggcgagaaagggccg
tgctgcgcttgccccaaaaccgaggccgagaagcaggccgagaaggaggaggccgagtac
cgcaaggtcttcgagaattttctgcacaacgccatcttcgtgcccagacccgaaaggaag
cggagagaggtcatgcaggtcgccaacaccaccacgtccagccgaagcaggaacactacg
gtggtggacacctacaacatcacagacccagaagagctcgagacagagtaccctttcttt
gaaagcagagtggacaacaaggagagaaccgtaatctctaacctccggccttttactttg
taccgcatcgacatccacagctgtaaccacgaggctgagaagctgggctgcagtgcctcc
aactttgtctttgcgagaaccatgcctgcagaaggagcagatgacattcctggaccggtg
acctgggagccaaggcctgagaactccatctttttaaagtggccagaacctgagaatccc
aatggattgattctaatgtatgaaataaaatacggatcactcgtcgaggatcagcgggag
tgtgtgtctagacaggactacaggaagtatggaggggccaagctgaaccggctcaaccca
gggaactacacggcccggatccaggccacctctctctctgggaatgggtcgtggacggat
cctgtgttcttctacgtccaggccaaaacgacgtatgaaaatttcatccatctgatcatc
gccctgcctgttgccgtgctgttgattgtgggcgggttggttataatgttgtacgtcttc
cacaggaaaagaaataacagcaggctggggaacggagtgctgtatgcttcggtgaacccg
gagtacttcagtgcagccgatgtgtacgtgcctgacgagtgggaggtcgcccgggagaag
atcaccatgagccgagagctggggcagggctccttcggcatggtttacgaaggcgttgcc
aagggtgtggtcaaagatgagcctgagaccagggtggccattaagacggtgaacgaggcc
gcgagcatgcgcgagaggattgagtttctcaatgaggcctcagtgatgaaggagttcaac
tgtcaccacgtggtgcgcctgctgggcgtggtgtcgcagggccagccgacgctggtcatc
atggagctcatgacccggggggacctcaaaagttatctccggtctctgaggccagaaatg
gagaataacccagtcctagcacctccaagcctaagcaaaatgatccagatggctggagag
attgcagacggcatggcatacctcaacgccaataagtttgtccacagagacctcgctgcc
cggaactgcatggtggccgaagatttcacagtcaaaatcggagattttgggatgacgaga
gacatctatgagacagactattaccggaaaggagggaaagggctgctgcccgtgcgctgg
atgtcccccgagtccctcaaggatggagtcttcaccacgcactccgacgtctggtccttc
ggggtcgtcctctgggagatcgccacgctggccgagcagccataccagggcttgtccaac
gagcaagtccttcgcttcgtcatggagggtggccttctggacaagccggacaactgtcct
gacatgctgtttgagctgatgcgcatgtgctggcagtacaaccccaagatgaggccctcc
ttcctggagatcatcagcagcatcaaggacgagatggagcccggcttccgggaggtgtcc
ttctactacagtgaggagaacaagccgcccgaacccgaggagctggacctggagccggag
aacatggagagcgtccccctggacccctcggcctcctcgtcctccctgccgctgcccgaa
agacactcaggacacaaggccgagaacggccccggccccggcgtgctggtcctgcgagcc
agcttcgacgagagacagccttacgcgcacatgaacgggggccgcaagaacgaacgggcc
ctgcctctgccccagtcttcgacctgctga
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integrated database retrieval system
