Cricetulus griseus (Chinese hamster): 100754506
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Entry
100754506 CDS
T02813
Symbol
Cftr
Name
(RefSeq) cystic fibrosis transmembrane conductance regulator
KO
K05031
cystic fibrosis transmembrane conductance regulator [EC:
5.6.1.6
]
Organism
cge
Cricetulus griseus (Chinese hamster)
Pathway
cge02010
ABC transporters
cge04024
cAMP signaling pathway
cge04152
AMPK signaling pathway
cge04530
Tight junction
cge04971
Gastric acid secretion
cge04972
Pancreatic secretion
cge04976
Bile secretion
Brite
KEGG Orthology (KO) [BR:
cge00001
]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
100754506 (Cftr)
09132 Signal transduction
04024 cAMP signaling pathway
100754506 (Cftr)
04152 AMPK signaling pathway
100754506 (Cftr)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04530 Tight junction
100754506 (Cftr)
09150 Organismal Systems
09154 Digestive system
04971 Gastric acid secretion
100754506 (Cftr)
04972 Pancreatic secretion
100754506 (Cftr)
04976 Bile secretion
100754506 (Cftr)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
cge02000
]
100754506 (Cftr)
Enzymes [BR:
cge01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.1 Enzymes altering polypeptide conformation or assembly
5.6.1.6 channel-conductance-controlling ATPase
100754506 (Cftr)
Transporters [BR:
cge02000
]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC7 subgroup
100754506 (Cftr)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ABC_membrane
CFTR_R
ABC_tran
AAA_21
SMC_N
AAA_29
RsgA_GTPase
T2SSE
TsaE
AAA_22
nSTAND3
AAA_16
DUF87
MeaB
AAA_30
NTPase_1
MMR_HSR1
AAA_23
NB-ARC
cobW
A2M
Motif
Other DBs
NCBI-GeneID:
100754506
NCBI-ProteinID:
XP_035307288
UniProt:
A0A9J7K381
LinkDB
All DBs
Position
1
Genome browser
AA seq
1606 aa
AA seq
DB search
MEAKEVSQWSLVTHKKHISSRRLALVSPDLVPEPSLILLLPEGRDVGGALEGAGSERQEK
EARAACKARRRKERTGRAWGVESRDWGWARQCWLLTWATEAGEEGREKGRRVGPSRVQPE
RVQTQTSVHHGDIMQKSPLEKASFISKLFFSWTTPILKKGYRQHLELSDVYQAPSSDSAD
HLSEQLEREWDREQASKKNPKLIHALRRCFFWRFIFYGILLYLGEVTKAVQPLLLGRIIA
SYDPDNKVERSIAIYLGIGLCLLFIVRTLLLHPAIFGLHRIGMQMRIAMFSLIYKKTLKL
SSRVLDKISIGQLVSLLSNNLNKFDEGLALAHFVWIAPLQVALLMGLLWELLQFSAFCGL
GLLIILVFFQAILGKMMVKYRDQKAAKINERLVITSEVIENIHSVKAYCWESAMENIIEN
LRQVELKLTKKAAYTRFLTSSAFFFSGFFVVLLAVLPYTVLNGIILRKIFTTISFCIVLR
MAVTRQLPTAVQTWYDSIGMITKVQDFLQYQEYKILEYNLMTTDVTMENVSAFWEEGFGE
LLEKVQLNNDDRKLSNDDDNPSLGHICFLENPVLKNISFKVEKGEMLAITGSTGAGKTSL
LMMILGELEASEGKIKHSGRISFCSQFSWIMPGTIKENIIFGVSYDEYRYKSIVSACQLE
KDISKFAEKDNTILGEGGVTLSGGQRARISLARAVYKDADVYLLDSPFGYLDVLTEEQIF
ENCVCKLMANKTRILVTSKMEHLKKADKILILHEGSSYFYGTFSELQSLRPDFSSKLMGY
DTFDQFTEERRSSILTETLRRFSVDDSSVTWSKTKQAFKQTGEYGEKRKSSVLSSMKKFS
IGQKIPFVIEDSDEFQDRRLSVVPESEQGETALPRSNMIPTGPAFSGGRRRQSVLDLMTH
TPTQGFSNIQRTRTSIRKISLAPQINLKDVDIYARRLSEDNAFNITEEVNEEDLKECFFD
DEVKITPVTTWNTYLRYFTLHKNLLIVLIWCLVVFLVEVAASLFVLWLLKNNPMHNGNNG
TKSTNNTYLVIITNTSFYYIFYIYVGVADTLLALSFFRGLPLVHTLITASKILHQKMLHS
ILHAPMSTFNSLKAGGIINRFSKDVAILDDFLPLTIFDFIQLLFIVIGAIIVVSVLQPYI
FLATVPGLVVFILLRAYFLHTSQQLKQLESEGRSPIFTHLVTSVKGLWTLRAFGRQPYFE
TLFHKALNLHTANWFMYLSTLRWFQMRIDMIFVLFFIVVTFISILTTGEGEGSTGIILTL
AMNIMSTLQWAVNTSIDVDSLMRSVSRVFKFIDLPQEESECSKIMKGLHPEEPSQVLVIE
NEHVKKTDTWPSRGEMVVKDLTVTYENDTNAMLENISFSISPGQRVGLLGRTGSGKSTLL
SAFLRLLNIQGDIQIDGVSWNSVTLKEWRKAFGVITQKVFIFSGTFRQNLDPHGKWRDEE
IWKVADEVGLKSVIEQFPGQLNFTLVDGGYVLSHGHKQLMGLARSVLSKARILLLDEPSA
HLDPITYQIIRKVLKHTFSGCTVILCEHRIEAILDCQRFLVIEEGTVWQYNSLQALLSEK
SVFQQAISPSEKMKLFQGRHSTKQKPRSQITALKEETEEEVQETRL
NT seq
4821 nt
NT seq
+upstream
nt +downstream
nt
atggaagccaaggaggtcagtcagtggtccttggtcacacataagaagcatattagctcc
cgcagattggccttggtttccccggacctggtgcctgagccgtcactgatattgctgctg
ccagaaggtagggatgtggggggggcgctggagggcgcggggagtgagcgccaggagaag
gaggcgcgggcggcatgcaaggcgcgcaggaggaaggagcgcacggggcgggcttggggc
gtggagagcagggactggggctgggctaggcagtgctggcttttaacctgggctacggag
gcgggggaggaaggcagagagaaggggaggcgtgtgggacccagtcgagtccaacctgaa
cgtgtccagacacagacctcagtgcaccacggagacatcatgcagaagtcgcctttggag
aaagccagctttatctccaaactctttttcagctggaccacaccaattttgaaaaaggga
tacagacagcacttggagttatcagatgtataccaagccccttcttctgattcagctgac
cacttgtctgaacagctagaaagagaatgggacagggaacaagcttcaaagaagaatccg
aagcttatccatgcccttcgacgatgcttcttctggagattcatcttctatgggatcttg
ttatacctaggggaagtcaccaaggctgtccagcctctcttgctaggaagaatcatagct
tcctatgatccagataacaaggtggagcgctccattgccatttacctaggtataggctta
tgtcttctcttcattgtcaggacgctgcttcttcatccagccatttttggccttcatcgc
attggaatgcagatgagaatagctatgtttagcttgatttataagaagactttaaagctg
tcaagccgtgttcttgataaaataagtattggacaacttgttagtcttctttccaacaac
ctgaacaaatttgatgaaggacttgccttggcacattttgtatggattgctcctttacaa
gtggctctcctgatgggtcttctctgggagttgttacaattctctgccttctgtggcctt
ggtttactgataatcctggtcttttttcaagctattttagggaagatgatggtgaagtac
agagatcaaaaagctgcaaaaatcaatgaaagacttgtgatcacatcagaagttattgag
aatatccattctgttaaggcatattgttgggaatcggcgatggaaaatataattgaaaac
ctgagacaggtggaactgaaactgaccaagaaggctgcctatacaaggttcttgactagc
tccgccttcttcttctcagggttctttgtagttcttttagctgtgcttccctatacagtc
ctcaacggaatcatcctccgaaaaatattcacaaccatttcattctgcattgtcctgcgt
atggcagtcacacgacagctccccactgctgtacaaacatggtatgattctattggaatg
ataacaaaagtacaggatttcctgcagtatcaagaatataagatactagagtataactta
atgaccacagatgtgaccatggagaatgtatcagcattctgggaggagggatttggagaa
ttgttggaaaaagtacaactaaacaatgatgacagaaaactttcaaatgatgatgacaac
ccaagtttgggtcatatctgttttctggaaaatcctgtgctgaaaaacatcagttttaag
gtagagaaaggagagatgttggctattactggatctactggagctggaaagacatcactt
ctgatgatgattttgggagagctggaagcttcagagggaaaaattaagcacagtggaaga
atttcattctgttctcaattttcttggattatgccgggtactatcaaagaaaatatcatc
tttggtgtttcctatgatgagtacagatataagagcattgtcagcgcttgccaactagag
aaggacatctccaagtttgcagaaaaagacaacaccattcttggagaaggtggagtcaca
ctgagtggaggtcaacgtgcaaggatttccttagcaagagcagtatataaagatgctgat
gtgtacctcttggattctccttttggatatctagatgttttaactgaagaacaaatattt
gaaaactgtgtctgtaaattgatggccaacaaaaccaggattttggtcacttctaaaatg
gaacatttaaagaaagctgacaaaatactaattttgcatgagggcagcagctatttctat
gggaccttttctgaattacaaagtctacgtccagacttcagttcaaaactcatggggtat
gatacttttgaccagtttactgaggaaagaagaagttcaattctaactgagaccttacgc
aggttctcagtagatgattcctctgtcacctggagcaaaaccaaacaggcatttaaacag
actggcgagtatggagaaaaaaggaagagctctgttctaagttctatgaagaaattttcc
attgggcaaaagattccatttgtcatagaagattctgatgagttccaagacaggagactc
tctgttgttccagagtctgaacagggagagacagccctgcctcgaagcaatatgatcccc
actggccccgcattttcaggaggcagaagaagacagtctgttttggacctcatgacacac
acacccacccaaggcttcagcaacatccagaggacaaggacttccattcgaaaaatctcc
ttagctcctcagataaatttaaaggatgtggatatatatgcaagacggttgtctgaggac
aatgcattcaacatcactgaagaagttaatgaagaagatttaaaggagtgtttttttgac
gatgaggtgaagataaccccggtgacgacatggaacacatacctccgatattttactctc
cataaaaacttgcttatagtgctgatttggtgcttggttgtttttctggttgaggtggct
gcttctttatttgtgttatggttgcttaaaaacaaccctatgcataatgggaacaatggt
actaaaagtacaaataacacctatcttgtgattatcaccaataccagcttctattatatt
ttttacatttacgtgggagtggctgacactctgcttgccttgagcttcttcagaggtttg
ccgctggtgcacacactaatcacagcatcaaaaattttacaccagaaaatgttacattct
attcttcatgcaccaatgtcaaccttcaactcgctgaaagcaggtgggattattaacaga
ttctccaaagatgttgcaattttggatgactttctacctcttaccatatttgacttcatc
cagttgctgttcattgtgattggagctataatagtcgtgtcggttttgcagccctacatc
ttcctggcaaccgtgcctgggttagtggtctttatcttactgagggcatatttccttcat
acctcccaacaactcaaacaactggaatctgaaggcaggagtccaattttcacccacctt
gttacaagtgtaaaaggactgtggacacttcgtgcctttggacgccaaccctactttgaa
actctgttccacaaagctctgaatttacacactgccaactggtttatgtatctgtcaacc
ttacgctggttccaaatgagaatagacatgatttttgtcctcttcttcattgttgttacc
ttcatttccattttgacaacaggtgaaggagaaggatcaactggcattattctaacttta
gctatgaatatcatgagtactttgcaatgggctgtaaacacaagcattgatgtggatagc
ttgatgcgatctgtaagcagagtctttaagtttattgatttaccacaagaagaaagtgag
tgttccaagataatgaaaggactgcatcccgaagaaccgtctcaagttttagttattgag
aatgaacatgtgaagaaaactgatacctggccctctaggggtgaaatggttgtcaaagac
ctcactgtgacatatgagaatgacacgaatgccatgttagagaacatttctttttcaata
agtcctggccagagggtgggcctcttaggaagaactggctcagggaaaagtactttgcta
tcagcatttctacgcttgttgaacattcaaggtgatatacagatcgatggcgtctcgtgg
aactcagtgaccttaaaagaatggaggaaagcttttggagtaataacacagaaagtattt
atcttttctggaacattcagacaaaacctggatccccatggaaaatggagagatgaagaa
atatggaaagttgcagatgaggttggactcaaatccgtgatagagcagtttcctgggcag
ctcaactttaccctcgtggatggaggttatgtactaagccatggccacaagcagctaatg
ggcttggctcgctctgttctcagtaaggccaggattttactgcttgatgagcccagtgcc
catctggatcccataacctaccaaataattcgaaaggttctaaaacacaccttcagtggt
tgcacagtaatcctctgtgaacacaggatagaagcaatattggattgtcagcgatttttg
gtcattgaagagggcaccgtgtggcagtacaactccctgcaggcgctgctgagtgagaag
agtgtcttccagcaggccatcagtccctcggaaaagatgaagctcttccagggccgccac
tccaccaagcagaagcctcgatcacagatcactgctctcaaagaggagacagaagaagaa
gtgcaggaaacccgtctctag
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