KEGG T02910: 100860845

KEGG Orthology (KO) [BR:chx00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100860845 (IL12B)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100860845 (IL12B)
09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100860845 (IL12B)
   04622 RIG-I-like receptor signaling pathway
    100860845 (IL12B)
   04625 C-type lectin receptor signaling pathway
    100860845 (IL12B)
   04658 Th1 and Th2 cell differentiation
    100860845 (IL12B)
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100860845 (IL12B)
   05205 Proteoglycans in cancer
    100860845 (IL12B)
  09163 Immune disease
   05321 Inflammatory bowel disease
    100860845 (IL12B)
   05330 Allograft rejection
    100860845 (IL12B)
  09167 Endocrine and metabolic disease
   04940 Type I diabetes mellitus
    100860845 (IL12B)
  09171 Infectious disease: bacterial
   05133 Pertussis
    100860845 (IL12B)
   05134 Legionellosis
    100860845 (IL12B)
   05152 Tuberculosis
    100860845 (IL12B)
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    100860845 (IL12B)
   05164 Influenza A
    100860845 (IL12B)
   05162 Measles
    100860845 (IL12B)
   05168 Herpes simplex virus 1 infection
    100860845 (IL12B)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    100860845 (IL12B)
   05145 Toxoplasmosis
    100860845 (IL12B)
   05140 Leishmaniasis
    100860845 (IL12B)
   05142 Chagas disease
    100860845 (IL12B)
   05143 African trypanosomiasis
    100860845 (IL12B)
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:chx04052]
    100860845 (IL12B)
   00536 Glycosaminoglycan binding proteins [BR:chx00536]
    100860845 (IL12B)
Cytokines and growth factors [BR:chx04052]
Cytokines
  Interleukins
   100860845 (IL12B)
Glycosaminoglycan binding proteins [BR:chx00536]
Heparan sulfate / Heparin
  Cytokines
   100860845 (IL12B)

SSDB

Motif

Pfam:

IL12p40_C Ig_5 Ig_4 Ig_3 fn3 Ig_2 I-set

Other DBs

NCBI-GeneID:

100860845

NCBI-ProteinID:

NP_001272629

UniProt:

P68221 Q6E218

LinkDB

Position

AA seq 327 aa
MHPQQLVVSWFSLVLLASPIVAIWELEKNVYVVELDWYPNAPGETVVLTCDTPEEDGITW
TSDQSSEVLGSGKTLTIQVKEFGDAGQYTCHKGGEVLSRSLLLLHKKEDGIWSTDILKDQ
KEPKAKSFLKCEAKDYSGHFTCSWLTAISTNLKFSVKSSRGSSDPRGVTCGAASLSAEKV
SMDHREYNKYTVECQEGSACPAAEESLPIEVVMEAVHKLKYENYTSSFFIRDIIKPDPPK
NLQLRPLKNSRQVEVSWEYPDTWSTPHSYFSLTFCVQVQGKNKREKKLFTDQTSAKVTCH
KDANIRVQARDRYYSSFWSEWASVSCS

NT seq 984 nt +upstreamnt +downstreamnt
atgcaccctcagcagttggtcgtttcctggttttccctggttttgctggcatctcccatc
gtggccatatgggaactggagaaaaatgtttatgttgtagaattggattggtatcctaat
gctcctggagaaacagtggtcctcacgtgtgacactcctgaagaagacggcatcacctgg
acctcagaccagagcagtgaggtcctgggctctggcaaaaccttgaccattcaagtcaaa
gagtttggagatgctgggcagtacacctgtcacaaaggaggcgaggttctgagtcgttca
ctcctcctgcttcacaaaaaggaagatggaatttggtccactgatattttaaaggatcag
aaagaacccaaagctaagagttttttaaaatgtgaggcaaaggattattctggacacttc
acctgctcgtggctgacagcaatcagtactaatctgaaattcagtgtcaaaagcagcaga
ggctcctctgacccccgaggggtgacgtgcggagcagcgtcactctcagcagagaaggtc
agcatggaccacagggagtataacaagtacacagtggagtgtcaggagggcagtgcctgc
ccggccgccgaggagagcctgcccattgaggtcgtgatggaagctgtgcacaagctcaag
tatgaaaactacaccagcagcttcttcatcagggacatcatcaaaccagacccacccaag
aacctgcaactgagaccactaaagaattctcggcaggtggaggtcagctgggagtaccct
gacacgtggagcaccccacattcctacttctccctgacgttttgtgttcaggtccaggga
aagaacaagagagaaaagaaactcttcacggaccaaacctcagccaaagtcacatgccac
aaggatgccaacatccgtgtgcaagcccgggaccgctactacagctcattctggagtgaa
tgggcatctgtgtcctgcagttag

Capra hircus (goat): 100861293

Entry

100861293 CDS T02910

Gene name

IL12A, IL-12A

Definition

(RefSeq) interleukin 12A

K05406

interleukin 12A

Organism

chx Capra hircus (goat)

Pathway

chx04060

Cytokine-cytokine receptor interaction

chx04620

Toll-like receptor signaling pathway

chx04622

RIG-I-like receptor signaling pathway

chx04625

C-type lectin receptor signaling pathway

chx04630

JAK-STAT signaling pathway

chx04658

Th1 and Th2 cell differentiation

chx04940

Type I diabetes mellitus

chx05133

Pertussis

chx05134

Legionellosis

chx05140

Leishmaniasis

chx05142

Chagas disease

chx05143

African trypanosomiasis

chx05144

Malaria

chx05145

Toxoplasmosis

chx05146

Amoebiasis

chx05152

Tuberculosis

chx05162

Measles

chx05164

Influenza A

chx05168

Herpes simplex virus 1 infection

chx05171

Coronavirus disease - COVID-19

chx05200

Pathways in cancer

chx05321

Inflammatory bowel disease

chx05330

Allograft rejection

Brite

KEGG Orthology (KO) [BR:chx00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100861293 (IL12A)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100861293 (IL12A)
09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100861293 (IL12A)
   04622 RIG-I-like receptor signaling pathway
    100861293 (IL12A)
   04625 C-type lectin receptor signaling pathway
    100861293 (IL12A)
   04658 Th1 and Th2 cell differentiation
    100861293 (IL12A)
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100861293 (IL12A)
  09163 Immune disease
   05321 Inflammatory bowel disease
    100861293 (IL12A)
   05330 Allograft rejection
    100861293 (IL12A)
  09167 Endocrine and metabolic disease
   04940 Type I diabetes mellitus
    100861293 (IL12A)
  09171 Infectious disease: bacterial
   05133 Pertussis
    100861293 (IL12A)
   05134 Legionellosis
    100861293 (IL12A)
   05152 Tuberculosis
    100861293 (IL12A)
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    100861293 (IL12A)
   05164 Influenza A
    100861293 (IL12A)
   05162 Measles
    100861293 (IL12A)
   05168 Herpes simplex virus 1 infection
    100861293 (IL12A)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    100861293 (IL12A)
   05144 Malaria
    100861293 (IL12A)
   05145 Toxoplasmosis
    100861293 (IL12A)
   05140 Leishmaniasis
    100861293 (IL12A)
   05142 Chagas disease
    100861293 (IL12A)
   05143 African trypanosomiasis
    100861293 (IL12A)
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:chx04052]
    100861293 (IL12A)
   00536 Glycosaminoglycan binding proteins [BR:chx00536]
    100861293 (IL12A)
Cytokines and growth factors [BR:chx04052]
Cytokines
  Interleukins
   100861293 (IL12A)
Glycosaminoglycan binding proteins [BR:chx00536]
Heparan sulfate / Heparin
  Cytokines
   100861293 (IL12A)

SSDB

Motif

Pfam:

IL12

Other DBs

NCBI-GeneID:

100861293

NCBI-ProteinID:

NP_001272567

UniProt:

O02814

LinkDB

Position

AA seq 221 aa
MCPLRSLLLISTLVLLHHLPHLSLGRSLPITTAGPGRSCLDYSQNLLRAVSNTLQKARQT
LEFYSCTSEEIDHEDITKDKTSTVEACLPLELATNESCLASRETSLITNGHCLASGKTSF
MTTLCLRSIYKDLKMYHMEFQAINAKLLMDPKRQVSLDQNMLAAIAELMQALNFDSETVP
QKPSLEELDFYKTKVKLCILLHAFRIRAVTIDRMMSYLSSS

NT seq 666 nt +upstreamnt +downstreamnt
atgtgcccgcttcgaagcctcctcctcatatccaccctggttctcctccaccacctgccc
cacctcagtttgggcaggagcctgcccatcaccactgcaggcccaggaaggagttgcctt
gactactcccaaaacctgctgagggccgtcagcaacacgctgcagaaggccagacaaacc
ctagaattttactcctgcacttctgaggagattgatcatgaagatatcaccaaagataaa
accagcacagtggaggcctgtttaccactggaattagccacgaatgagagttgcctggct
tccagagagacctctttaataactaatgggcattgtctggcttctggaaagacctctttt
atgacaaccctgtgccttagaagtatctacaaggacttgaagatgtaccacatggagttc
caggccattaatgcaaagcttctgatggatcctaagaggcaagtctctctagaccagaac
atgctggcagctattgctgagctaatgcaggccctgaatttcgacagtgagactgtgcca
cagaaaccctccctggaagaactggatttttacaagacaaaagtcaagctctgcatcctt
cttcacgccttcagaattcgtgcagtgaccatcgacagaatgatgagctatctgagttct
tcctag

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