Capra hircus (goat): 102169370
Help
Entry
102169370 CDS
T02910
Gene name
ARAF
Definition
(RefSeq) A-Raf proto-oncogene, serine/threonine kinase
KO
K08845
A-Raf proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
chx
Capra hircus (goat)
Pathway
chx01521
EGFR tyrosine kinase inhibitor resistance
chx01522
Endocrine resistance
chx04010
MAPK signaling pathway
chx04012
ErbB signaling pathway
chx04068
FoxO signaling pathway
chx04270
Vascular smooth muscle contraction
chx04650
Natural killer cell mediated cytotoxicity
chx04720
Long-term potentiation
chx04726
Serotonergic synapse
chx04730
Long-term depression
chx04810
Regulation of actin cytoskeleton
chx04910
Insulin signaling pathway
chx04914
Progesterone-mediated oocyte maturation
chx04928
Parathyroid hormone synthesis, secretion and action
chx05010
Alzheimer disease
chx05022
Pathways of neurodegeneration - multiple diseases
chx05034
Alcoholism
chx05160
Hepatitis C
chx05161
Hepatitis B
chx05200
Pathways in cancer
chx05205
Proteoglycans in cancer
chx05210
Colorectal cancer
chx05211
Renal cell carcinoma
chx05212
Pancreatic cancer
chx05213
Endometrial cancer
chx05214
Glioma
chx05215
Prostate cancer
chx05218
Melanoma
chx05219
Bladder cancer
chx05220
Chronic myeloid leukemia
chx05221
Acute myeloid leukemia
chx05223
Non-small cell lung cancer
chx05224
Breast cancer
chx05225
Hepatocellular carcinoma
chx05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
chx00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102169370 (ARAF)
04012 ErbB signaling pathway
102169370 (ARAF)
04068 FoxO signaling pathway
102169370 (ARAF)
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
102169370 (ARAF)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
102169370 (ARAF)
09152 Endocrine system
04910 Insulin signaling pathway
102169370 (ARAF)
04914 Progesterone-mediated oocyte maturation
102169370 (ARAF)
04928 Parathyroid hormone synthesis, secretion and action
102169370 (ARAF)
09153 Circulatory system
04270 Vascular smooth muscle contraction
102169370 (ARAF)
09156 Nervous system
04726 Serotonergic synapse
102169370 (ARAF)
04720 Long-term potentiation
102169370 (ARAF)
04730 Long-term depression
102169370 (ARAF)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102169370 (ARAF)
05205 Proteoglycans in cancer
102169370 (ARAF)
09162 Cancer: specific types
05210 Colorectal cancer
102169370 (ARAF)
05212 Pancreatic cancer
102169370 (ARAF)
05225 Hepatocellular carcinoma
102169370 (ARAF)
05226 Gastric cancer
102169370 (ARAF)
05214 Glioma
102169370 (ARAF)
05221 Acute myeloid leukemia
102169370 (ARAF)
05220 Chronic myeloid leukemia
102169370 (ARAF)
05218 Melanoma
102169370 (ARAF)
05211 Renal cell carcinoma
102169370 (ARAF)
05219 Bladder cancer
102169370 (ARAF)
05215 Prostate cancer
102169370 (ARAF)
05213 Endometrial cancer
102169370 (ARAF)
05224 Breast cancer
102169370 (ARAF)
05223 Non-small cell lung cancer
102169370 (ARAF)
09164 Neurodegenerative disease
05010 Alzheimer disease
102169370 (ARAF)
05022 Pathways of neurodegeneration - multiple diseases
102169370 (ARAF)
09165 Substance dependence
05034 Alcoholism
102169370 (ARAF)
09172 Infectious disease: viral
05161 Hepatitis B
102169370 (ARAF)
05160 Hepatitis C
102169370 (ARAF)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
102169370 (ARAF)
01522 Endocrine resistance
102169370 (ARAF)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
chx01001
]
102169370 (ARAF)
Enzymes [BR:
chx01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
102169370 (ARAF)
Protein kinases [BR:
chx01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
102169370 (ARAF)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
RBD
C1_1
Kinase-like
zf-RING-like
Pkinase_fungal
APH
TUG-UBL1
Kdo
Motif
Other DBs
NCBI-GeneID:
102169370
NCBI-ProteinID:
XP_005700894
UniProt:
A0A452FPR8
LinkDB
All DBs
Position
X
AA seq
611 aa
AA seq
DB search
MEPPRGPPANGAEPSRSVGTVKVYLPNKQRTVVTVRDGMSVYDSLDKALKVRGLNQDCCV
VYRLIKGRKTVTAWDTAIAPLDGEELIVEVLEDVPLTMHNFVRKTFFSLAFCDFCLKFLF
HGFRCQTCGYKFHQHCSSKVPTVCVDMSTNRRQFYHSVQDLSGSSRQHEVPSNRPLNEPL
TPQSPSLSPASSCTQHRDPEHFSFPAQANTPLQRIRSTSTPNVHMVSTTAPMDSGLIQLT
GQNFNTDAAGNRGGGDGAPRGSPSPASVSSGRKSPHSKSPSEQRERKSLADDKKKVKNLG
YRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRGRWHGDVAVKVLKVAQPTAEQAQAFKNEM
QVLRKTRHVNILLFMGFMTRPGFAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQ
GMDYLHAKNIIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAA
EVIRMQDPNPYSFQSDVYAYGVVLYELMTGSLPYSHIGSRDQIIFMVGRGYLSPDLSKIS
SNCPKAMRRLLSDCLKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHRTQADELP
ACLLSAARLVP
NT seq
1836 nt
NT seq
+upstream
nt +downstream
nt
atggagccaccacggggcccccctgctaatggggccgagccctcccggtcagtgggcacc
gtcaaagtgtacctgcccaacaagcagcgcacggtggtgactgtccgggacggcatgagt
gtctatgactctctagacaaggccctcaaggtgcggggtctcaatcaagattgctgtgtg
gtttaccggctcatcaaggggcgaaagacagtcactgcctgggacacagccattgccccg
ctggatggcgaggagctcattgtggaggtcctcgaagacgtccccctgaccatgcacaat
tttgtacggaagacattcttcagcctggccttctgtgacttctgccttaagtttctgttc
catggcttccgctgccaaacctgtggatacaagttccaccagcattgttcctccaaggtc
cccacagtctgtgtcgacatgagtaccaaccgccgacagttctaccacagtgtccaggat
ttgtccggaagctccagacagcacgaggttccctcaaaccgccccctgaatgagccgctc
acccctcagagtcccagcctttcccctgccagctcctgcacccagcaccgcgaccccgag
cacttctccttccctgcccaggccaacacccccctccagcgcatccgctccacatccacc
cccaatgtccacatggtcagcaccacagcccccatggactccggcctcatccagctcact
ggccagaacttcaacactgatgctgctgggaatagaggtggtggcgatggagccccccgg
gggagccccagcccagccagtgtgtcctcgggaaggaagtccccacattccaagtcccca
tcagagcagcgggaacggaagtccttggctgatgacaagaagaaagtgaagaatttgggg
taccgggactcgggctattactgggaggtgccacccagtgaggtgcagttgctgaagagg
atcgggacgggctcgtttggcacggtgtttcgcgggcggtggcatggcgatgtggccgtg
aaggtgctcaaggtggcccaacccacagctgagcaggcccaggccttcaagaacgagatg
caggtgctcaggaagacacgtcatgtcaacatcttgctgttcatgggcttcatgacccgg
ccaggatttgccatcatcacacagtggtgtgagggctccagtctctaccaccacctgcat
gtggctgacacacgcttcgacatggtccagctcattgatgtggcccgccagactgctcag
ggcatggactacctccatgccaagaacatcatccaccgagatctcaagtctaacaacatc
ttcctgcacgaggggctcacggtgaagatcggggacttcggcctggccacagtaaagacg
cggtggagtggggcccagcccttggagcaaccctcaggctctgtgctatggatggcagct
gaggtgatccgtatgcaggacccgaacccctacagcttccagtcagatgtctacgcctat
ggggttgtgctctatgagctcatgaccggctcactgccttacagccacattggcagccga
gaccagattatctttatggtgggccgtggctatctgtccccggacctcagcaaaatctcc
agcaattgccccaaggccatgaggcgcctgctgtctgactgcctgaagttccagcgagag
gagcggcccctttttccccagatcctggccacgattgagctgctgcagcggtcactcccc
aagattgagcggagtgcctccgaaccctccttgcaccgtacccaggctgatgagttgcct
gcctgcctactcagcgcagcccgccttgtgccttag
Capra hircus (goat): 102174360
Help
Entry
102174360 CDS
T02910
Gene name
BRAF
Definition
(RefSeq) B-Raf proto-oncogene, serine/threonine kinase
KO
K04365
B-Raf proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
chx
Capra hircus (goat)
Pathway
chx01521
EGFR tyrosine kinase inhibitor resistance
chx01522
Endocrine resistance
chx04010
MAPK signaling pathway
chx04012
ErbB signaling pathway
chx04015
Rap1 signaling pathway
chx04024
cAMP signaling pathway
chx04062
Chemokine signaling pathway
chx04068
FoxO signaling pathway
chx04150
mTOR signaling pathway
chx04270
Vascular smooth muscle contraction
chx04510
Focal adhesion
chx04650
Natural killer cell mediated cytotoxicity
chx04720
Long-term potentiation
chx04722
Neurotrophin signaling pathway
chx04726
Serotonergic synapse
chx04730
Long-term depression
chx04810
Regulation of actin cytoskeleton
chx04910
Insulin signaling pathway
chx04914
Progesterone-mediated oocyte maturation
chx04928
Parathyroid hormone synthesis, secretion and action
chx04934
Cushing syndrome
chx05010
Alzheimer disease
chx05022
Pathways of neurodegeneration - multiple diseases
chx05034
Alcoholism
chx05160
Hepatitis C
chx05161
Hepatitis B
chx05200
Pathways in cancer
chx05205
Proteoglycans in cancer
chx05210
Colorectal cancer
chx05211
Renal cell carcinoma
chx05212
Pancreatic cancer
chx05213
Endometrial cancer
chx05214
Glioma
chx05215
Prostate cancer
chx05216
Thyroid cancer
chx05218
Melanoma
chx05219
Bladder cancer
chx05220
Chronic myeloid leukemia
chx05221
Acute myeloid leukemia
chx05223
Non-small cell lung cancer
chx05224
Breast cancer
chx05225
Hepatocellular carcinoma
chx05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
chx00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102174360 (BRAF)
04012 ErbB signaling pathway
102174360 (BRAF)
04015 Rap1 signaling pathway
102174360 (BRAF)
04068 FoxO signaling pathway
102174360 (BRAF)
04024 cAMP signaling pathway
102174360 (BRAF)
04150 mTOR signaling pathway
102174360 (BRAF)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
102174360 (BRAF)
09142 Cell motility
04810 Regulation of actin cytoskeleton
102174360 (BRAF)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
102174360 (BRAF)
04062 Chemokine signaling pathway
102174360 (BRAF)
09152 Endocrine system
04910 Insulin signaling pathway
102174360 (BRAF)
04914 Progesterone-mediated oocyte maturation
102174360 (BRAF)
04928 Parathyroid hormone synthesis, secretion and action
102174360 (BRAF)
09153 Circulatory system
04270 Vascular smooth muscle contraction
102174360 (BRAF)
09156 Nervous system
04726 Serotonergic synapse
102174360 (BRAF)
04720 Long-term potentiation
102174360 (BRAF)
04730 Long-term depression
102174360 (BRAF)
04722 Neurotrophin signaling pathway
102174360 (BRAF)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102174360 (BRAF)
05205 Proteoglycans in cancer
102174360 (BRAF)
09162 Cancer: specific types
05210 Colorectal cancer
102174360 (BRAF)
05212 Pancreatic cancer
102174360 (BRAF)
05225 Hepatocellular carcinoma
102174360 (BRAF)
05226 Gastric cancer
102174360 (BRAF)
05214 Glioma
102174360 (BRAF)
05216 Thyroid cancer
102174360 (BRAF)
05221 Acute myeloid leukemia
102174360 (BRAF)
05220 Chronic myeloid leukemia
102174360 (BRAF)
05218 Melanoma
102174360 (BRAF)
05211 Renal cell carcinoma
102174360 (BRAF)
05219 Bladder cancer
102174360 (BRAF)
05215 Prostate cancer
102174360 (BRAF)
05213 Endometrial cancer
102174360 (BRAF)
05224 Breast cancer
102174360 (BRAF)
05223 Non-small cell lung cancer
102174360 (BRAF)
09164 Neurodegenerative disease
05010 Alzheimer disease
102174360 (BRAF)
05022 Pathways of neurodegeneration - multiple diseases
102174360 (BRAF)
09165 Substance dependence
05034 Alcoholism
102174360 (BRAF)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
102174360 (BRAF)
09172 Infectious disease: viral
05161 Hepatitis B
102174360 (BRAF)
05160 Hepatitis C
102174360 (BRAF)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
102174360 (BRAF)
01522 Endocrine resistance
102174360 (BRAF)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
chx01001
]
102174360 (BRAF)
Enzymes [BR:
chx01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
102174360 (BRAF)
Protein kinases [BR:
chx01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
102174360 (BRAF)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
RBD
C1_1
Kinase-like
zf-RING-like
C1_2
Pkinase_fungal
APH
Kdo
Motif
Other DBs
NCBI-GeneID:
102174360
NCBI-ProteinID:
XP_017902346
UniProt:
A0A452F5E2
LinkDB
All DBs
Position
4
AA seq
764 aa
AA seq
DB search
MAALSGGGGGGGAEQGQALFNGDMEPEAGAAASSAADPAIPEEVWNIKQMIKLTQEHIEA
LLDKFGGEHNPPSIYLEAYEEYTSKLDALQQREQQLLESLGNGTDFSVSSSASTDTVTSS
SSSSLSVLPSSLSVFQNPTDVSRSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDSLKK
ALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFF
TLAFCDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMCVNYDQLDLLFVSKFFEHHPIPQE
EASLAETTLPCGSSPSAPPSDSIGPPILTSPSPSKSIPIPQPFRPADEDHRNQFGQRDRS
SSAPNVHINTIEPVNIDDLIRDQGFRSDGGSTTGLSATPPASLPGSLSNVKALQKSPGPQ
RERKSSSSSEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVK
MLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHI
IETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSR
WSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRD
QIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPK
IHRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYGEFAAFK
NT seq
2295 nt
NT seq
+upstream
nt +downstream
nt
atggcggcgctgagcggcggtggcggcggcggcggcgcggagcagggccaggctctgttc
aacggggacatggagcccgaggccggcgccgcggcctcttcggctgcggaccccgccatt
cccgaggaggtgtggaatatcaaacaaatgattaagttgacacaggagcatatagaggcc
ctattggacaaatttggtggggagcataatccaccatcaatatatctggaggcctatgaa
gaatacaccagcaagctagacgccctccaacaaagagaacaacagttattggaatccctg
gggaatggaactgatttttctgtttctagctctgcatcaacggacaccgttacatcttct
tcctcttctagcctttcagtgctgccttcatctctttcagtttttcaaaatcccacagat
gtgtcacggagcaaccccaagtcaccacaaaaacctatcgttagagtcttcctgcccaat
aaacagaggacagtggtacctgcacggtgtggagtcacagtccgggacagcctgaagaag
gcactgatgatgagaggtctaatcccagagtgctgtgctgtttacagaattcaggatggg
gagaagaaaccaattggctgggacactgatatttcctggcttactggagaggaattgcat
gtagaagtgttggagaatgttccacttacaacacacaactttgtacggaaaacttttttc
accttagcattttgtgacttctgtagaaagctgcttttccaggggttccgctgtcaaaca
tgtggttataaatttcaccagcgttgtagtacagaggttccactgatgtgtgttaattat
gaccaactagatttgctgtttgtctccaagttctttgaacaccacccaataccacaggag
gaggcctccttagcagagactacccttccatgtggctcatccccttctgcacccccctcc
gattctattgggcccccaattctcaccagtccatctccttcaaaatccattccaattcca
cagcctttccgaccagcagatgaagatcatcgaaatcagtttggacaacgagaccggtcc
tcatcagctccaaatgtgcatataaacacaatagaacctgtcaatattgatgacttgatt
agagaccaagggtttcgtagtgatggaggatcaaccacaggtttatctgccacaccccct
gcctcattacctggctcactctctaatgtgaaagcattgcagaaatctccaggacctcag
cgagaaaggaagtcctcttcatcctcagaagacaggaatcgaatgaaaacgcttggtaga
cgggattcaagtgacgattgggagattcctgatggacagatcacagtgggacaaagaatt
ggatcagggtcatttgggacagtctacaagggaaagtggcatggtgatgtggcagtgaaa
atgttgaatgtgacagcacccacacctcagcagttacaggccttcaaaaatgaagtagga
gtactcaggaaaacacgacatgtgaatatcctcctcttcatgggttattcaacaaagcca
caactggctattgttacccagtggtgtgagggctccagtttatatcatcatctccacatc
attgagaccaaattcgagatgatcaaacttatagatattgcacggcagactgcacagggc
atggattacttacacgccaagtcaatcatccacagagacctcaagagtaataatattttt
cttcatgaagacctcacagtaaaaataggtgattttggtctagccacagtgaaatctcga
tggagtgggtcccatcagtttgaacagttgtctggatccattttgtggatggcaccagaa
gtaatcagaatgcaagataaaaacccatatagctttcagtcagatgtatatgcatttggg
attgttctgtatgaattgatgaccggacagttaccttattcaaatatcaacaacagggac
cagataatttttatggtgggacgaggatatctgtctccagatctcagtaaggtacggagt
aactgtccaaaagccatgaagagattaatggcagagtgcctaaaaaagaaaagagatgaa
agaccactctttccccaaattctcgcctctattgagctgctggcccgctcattgccaaaa
attcaccgcagtgcatcagaaccctccttgaatcgggctggcttccaaacagaggatttt
agtctatatgcttgtgcttctccaaaaacacccattcaggcagggggatatggagaattt
gcagccttcaagtag
Capra hircus (goat): 108638619
Help
Entry
108638619 CDS
T02910
Gene name
RAF1
Definition
(RefSeq) Raf-1 proto-oncogene, serine/threonine kinase
KO
K04366
RAF proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
chx
Capra hircus (goat)
Pathway
chx01521
EGFR tyrosine kinase inhibitor resistance
chx01522
Endocrine resistance
chx04010
MAPK signaling pathway
chx04012
ErbB signaling pathway
chx04014
Ras signaling pathway
chx04015
Rap1 signaling pathway
chx04022
cGMP-PKG signaling pathway
chx04024
cAMP signaling pathway
chx04062
Chemokine signaling pathway
chx04068
FoxO signaling pathway
chx04071
Sphingolipid signaling pathway
chx04072
Phospholipase D signaling pathway
chx04140
Autophagy - animal
chx04150
mTOR signaling pathway
chx04151
PI3K-Akt signaling pathway
chx04210
Apoptosis
chx04218
Cellular senescence
chx04270
Vascular smooth muscle contraction
chx04360
Axon guidance
chx04370
VEGF signaling pathway
chx04371
Apelin signaling pathway
chx04510
Focal adhesion
chx04540
Gap junction
chx04550
Signaling pathways regulating pluripotency of stem cells
chx04613
Neutrophil extracellular trap formation
chx04625
C-type lectin receptor signaling pathway
chx04630
JAK-STAT signaling pathway
chx04650
Natural killer cell mediated cytotoxicity
chx04660
T cell receptor signaling pathway
chx04662
B cell receptor signaling pathway
chx04664
Fc epsilon RI signaling pathway
chx04666
Fc gamma R-mediated phagocytosis
chx04720
Long-term potentiation
chx04722
Neurotrophin signaling pathway
chx04726
Serotonergic synapse
chx04730
Long-term depression
chx04810
Regulation of actin cytoskeleton
chx04910
Insulin signaling pathway
chx04912
GnRH signaling pathway
chx04914
Progesterone-mediated oocyte maturation
chx04915
Estrogen signaling pathway
chx04916
Melanogenesis
chx04917
Prolactin signaling pathway
chx04919
Thyroid hormone signaling pathway
chx04921
Oxytocin signaling pathway
chx04926
Relaxin signaling pathway
chx04928
Parathyroid hormone synthesis, secretion and action
chx04929
GnRH secretion
chx04935
Growth hormone synthesis, secretion and action
chx05010
Alzheimer disease
chx05022
Pathways of neurodegeneration - multiple diseases
chx05034
Alcoholism
chx05132
Salmonella infection
chx05152
Tuberculosis
chx05160
Hepatitis C
chx05161
Hepatitis B
chx05163
Human cytomegalovirus infection
chx05164
Influenza A
chx05165
Human papillomavirus infection
chx05167
Kaposi sarcoma-associated herpesvirus infection
chx05170
Human immunodeficiency virus 1 infection
chx05200
Pathways in cancer
chx05205
Proteoglycans in cancer
chx05206
MicroRNAs in cancer
chx05210
Colorectal cancer
chx05211
Renal cell carcinoma
chx05212
Pancreatic cancer
chx05213
Endometrial cancer
chx05214
Glioma
chx05215
Prostate cancer
chx05218
Melanoma
chx05219
Bladder cancer
chx05220
Chronic myeloid leukemia
chx05221
Acute myeloid leukemia
chx05223
Non-small cell lung cancer
chx05224
Breast cancer
chx05225
Hepatocellular carcinoma
chx05226
Gastric cancer
chx05230
Central carbon metabolism in cancer
chx05231
Choline metabolism in cancer
chx05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
chx00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
108638619 (RAF1)
04012 ErbB signaling pathway
108638619 (RAF1)
04014 Ras signaling pathway
108638619 (RAF1)
04015 Rap1 signaling pathway
108638619 (RAF1)
04370 VEGF signaling pathway
108638619 (RAF1)
04371 Apelin signaling pathway
108638619 (RAF1)
04630 JAK-STAT signaling pathway
108638619 (RAF1)
04068 FoxO signaling pathway
108638619 (RAF1)
04072 Phospholipase D signaling pathway
108638619 (RAF1)
04071 Sphingolipid signaling pathway
108638619 (RAF1)
04024 cAMP signaling pathway
108638619 (RAF1)
04022 cGMP-PKG signaling pathway
108638619 (RAF1)
04151 PI3K-Akt signaling pathway
108638619 (RAF1)
04150 mTOR signaling pathway
108638619 (RAF1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
108638619 (RAF1)
09143 Cell growth and death
04210 Apoptosis
108638619 (RAF1)
04218 Cellular senescence
108638619 (RAF1)
09144 Cellular community - eukaryotes
04510 Focal adhesion
108638619 (RAF1)
04540 Gap junction
108638619 (RAF1)
04550 Signaling pathways regulating pluripotency of stem cells
108638619 (RAF1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
108638619 (RAF1)
09150 Organismal Systems
09151 Immune system
04613 Neutrophil extracellular trap formation
108638619 (RAF1)
04625 C-type lectin receptor signaling pathway
108638619 (RAF1)
04650 Natural killer cell mediated cytotoxicity
108638619 (RAF1)
04660 T cell receptor signaling pathway
108638619 (RAF1)
04662 B cell receptor signaling pathway
108638619 (RAF1)
04664 Fc epsilon RI signaling pathway
108638619 (RAF1)
04666 Fc gamma R-mediated phagocytosis
108638619 (RAF1)
04062 Chemokine signaling pathway
108638619 (RAF1)
09152 Endocrine system
04910 Insulin signaling pathway
108638619 (RAF1)
04929 GnRH secretion
108638619 (RAF1)
04912 GnRH signaling pathway
108638619 (RAF1)
04915 Estrogen signaling pathway
108638619 (RAF1)
04914 Progesterone-mediated oocyte maturation
108638619 (RAF1)
04917 Prolactin signaling pathway
108638619 (RAF1)
04921 Oxytocin signaling pathway
108638619 (RAF1)
04926 Relaxin signaling pathway
108638619 (RAF1)
04935 Growth hormone synthesis, secretion and action
108638619 (RAF1)
04919 Thyroid hormone signaling pathway
108638619 (RAF1)
04928 Parathyroid hormone synthesis, secretion and action
108638619 (RAF1)
04916 Melanogenesis
108638619 (RAF1)
09153 Circulatory system
04270 Vascular smooth muscle contraction
108638619 (RAF1)
09156 Nervous system
04726 Serotonergic synapse
108638619 (RAF1)
04720 Long-term potentiation
108638619 (RAF1)
04730 Long-term depression
108638619 (RAF1)
04722 Neurotrophin signaling pathway
108638619 (RAF1)
09158 Development and regeneration
04360 Axon guidance
108638619 (RAF1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
108638619 (RAF1)
05206 MicroRNAs in cancer
108638619 (RAF1)
05205 Proteoglycans in cancer
108638619 (RAF1)
05230 Central carbon metabolism in cancer
108638619 (RAF1)
05231 Choline metabolism in cancer
108638619 (RAF1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
108638619 (RAF1)
09162 Cancer: specific types
05210 Colorectal cancer
108638619 (RAF1)
05212 Pancreatic cancer
108638619 (RAF1)
05225 Hepatocellular carcinoma
108638619 (RAF1)
05226 Gastric cancer
108638619 (RAF1)
05214 Glioma
108638619 (RAF1)
05221 Acute myeloid leukemia
108638619 (RAF1)
05220 Chronic myeloid leukemia
108638619 (RAF1)
05218 Melanoma
108638619 (RAF1)
05211 Renal cell carcinoma
108638619 (RAF1)
05219 Bladder cancer
108638619 (RAF1)
05215 Prostate cancer
108638619 (RAF1)
05213 Endometrial cancer
108638619 (RAF1)
05224 Breast cancer
108638619 (RAF1)
05223 Non-small cell lung cancer
108638619 (RAF1)
09164 Neurodegenerative disease
05010 Alzheimer disease
108638619 (RAF1)
05022 Pathways of neurodegeneration - multiple diseases
108638619 (RAF1)
09165 Substance dependence
05034 Alcoholism
108638619 (RAF1)
09171 Infectious disease: bacterial
05132 Salmonella infection
108638619 (RAF1)
05152 Tuberculosis
108638619 (RAF1)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
108638619 (RAF1)
05161 Hepatitis B
108638619 (RAF1)
05160 Hepatitis C
108638619 (RAF1)
05164 Influenza A
108638619 (RAF1)
05163 Human cytomegalovirus infection
108638619 (RAF1)
05167 Kaposi sarcoma-associated herpesvirus infection
108638619 (RAF1)
05165 Human papillomavirus infection
108638619 (RAF1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
108638619 (RAF1)
01522 Endocrine resistance
108638619 (RAF1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
chx01001
]
108638619 (RAF1)
Enzymes [BR:
chx01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
108638619 (RAF1)
Protein kinases [BR:
chx01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
108638619 (RAF1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
RBD
C1_1
Kinase-like
zf-RING-like
Pkinase_fungal
C1_2
Motif
Other DBs
NCBI-GeneID:
108638619
NCBI-ProteinID:
XP_017922447
UniProt:
A0A452DTI5
LinkDB
All DBs
Position
22
AA seq
648 aa
AA seq
DB search
MEHIQGAWKTISNGFGFKDTVFDGASCISPTIVQQFGYQRRASDDGKLTDPSKTSNTIRV
FLPNKQRTVVNVRNGMSLHDCLMKALKVRGLQPECCAVFRLLHEHKGKKARLDWNTDAAS
LIGEELQVDFLDHVPLTTHNFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKV
PTMCVDWSNIRQLLLFPNSTVGDGGVPALPSLTMRRMRESVSRIPPGSQHRYSTPHAFTF
STSSPSSEGSLSQRQRSTSTPNVHMVSAALPVDSRMIEDAIRSHSESGSPSALSSSPNNL
SPTGWSQPKTPAPAQRERAPGSSTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSF
GTVYKGKWHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIV
TQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGL
TVKIGDFGLATVKSRWSGSQQVEQPTGSILWMAPEVIRMQDNNPFSFQSDVYSYGIVLYE
LMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKEERPLFP
QILSSIELLQHSLPKINRSASEPSLHRAAHTEDINACTLTTSPRLPVF
NT seq
1947 nt
NT seq
+upstream
nt +downstream
nt
atggagcacatacagggcgcctggaagacgatcagcaacggtttcgggttcaaagacacg
gtgtttgacggcgccagctgcatctcccctacaatagttcagcagtttggctatcagcgt
cgggcgtcagatgatggcaagcttacggacccttctaagacaagcaacactatccgtgtg
tttttgccaaacaagcaaagaacagtggtcaacgtgcggaatggaatgagcttgcatgac
tgccttatgaaagctctcaaggtgaggggcctgcaaccagagtgctgtgcagtgttcaga
cttctccacgaacacaagggtaaaaaagcacggttagattggaatactgatgctgcctcg
ttgatcggagaggaacttcaagtggatttcctggatcatgttcccctcacaacacacaac
tttgctcggaaaaccttcctgaagcttgccttctgtgacatctgtcagaagttcttgcta
aatggatttagatgtcagacttgtggctacaagtttcacgagcattgtagcaccaaagta
cccactatgtgtgtggactggagtaatatcagacagctcttattgttcccaaattccact
gttggtgatggcggggtcccagcgctgccttctttgacgatgcgtcggatgcgagagtct
gtttcccggatacctcctggttcccagcacagatactccacaccccacgctttcacattc
agcacctccagcccctcctctgaaggctccctctcccagaggcagaggtcgacgtccacg
ccaaacgtgcacatggtcagcgccgctctgcccgtggacagcaggatgatcgaggatgca
attcgaagtcacagtgaatcaggctccccttcagccttgtccagcagccccaacaatctg
agcccgacaggctggtcacagcccaaaacccctgcgcctgcccagagagagcgggcgcca
ggctccagcacccaggagaagaacaaaattaggcctcgtggacagagagattcgagctat
tactgggagatagaagccagtgaagtgatgctgtccactcggattggatcaggctccttc
gggactgtttataagggcaagtggcatggagatgttgcagtaaagattctgaaggttgtt
gaccccacgccagagcagttccaggccttcaggaacgaggtggctgtcctccgcaaaacc
cggcacgtgaacatcctgctcttcatggggtacatgacgaaggacaacctggcgatagtg
acgcagtggtgcgagggcagcagcctctacaagcacctgcacgtccaggagaccaagttc
cagatgttccagctgattgacattgcccggcagacggctcagggaatggactatttgcat
gcaaagaacatcatccacagagacatgaaatccaataatatatttctccacgaaggccta
acggtgaaaatcggcgattttggattggccacggtgaagtcgcgctggagtggttctcag
caggtcgagcagcccaccggctccatcctgtggatggccccagaggtgatccggatgcag
gataataacccgttcagcttccagtctgacgtctattcctatggcatcgtgctgtatgag
ctcatgacgggggagctcccttactcccacatcaacaaccgcgaccagatcatcttcatg
gtgggccgcgggtacgcctccccagacctcagcaagctgtacaagaactgccccaaagcc
atgaagaggctggtagccgactgtgtgaagaaagtgaaggaagagaggcctctttttccc
cagatcctgtcttccatcgagctgctccagcactctctgcccaagatcaaccggagcgcc
tcggagccctccctgcaccgagcggcccacaccgaggacatcaacgcctgcacgctgacc
acgtcccctcggctgcccgtcttctag
DBGET
integrated database retrieval system
