KEGG   Capra hircus (goat): 102169919
Entry
102169919         CDS       T02910                                 

Gene name
CASP8, CASP8-s
Definition
(RefSeq) caspase 8
  KO
K04398  caspase 8 [EC:3.4.22.61]
Organism
chx  Capra hircus (goat)
Pathway
chx01524  Platinum drug resistance
chx04115  p53 signaling pathway
chx04210  Apoptosis
chx04215  Apoptosis - multiple species
chx04217  Necroptosis
chx04620  Toll-like receptor signaling pathway
chx04621  NOD-like receptor signaling pathway
chx04622  RIG-I-like receptor signaling pathway
chx04625  C-type lectin receptor signaling pathway
chx04657  IL-17 signaling pathway
chx04668  TNF signaling pathway
chx04932  Non-alcoholic fatty liver disease
chx05010  Alzheimer disease
chx05016  Huntington disease
chx05022  Pathways of neurodegeneration - multiple diseases
chx05132  Salmonella infection
chx05134  Legionellosis
chx05142  Chagas disease
chx05145  Toxoplasmosis
chx05152  Tuberculosis
chx05160  Hepatitis C
chx05161  Hepatitis B
chx05162  Measles
chx05163  Human cytomegalovirus infection
chx05164  Influenza A
chx05165  Human papillomavirus infection
chx05167  Kaposi sarcoma-associated herpesvirus infection
chx05168  Herpes simplex virus 1 infection
chx05169  Epstein-Barr virus infection
chx05170  Human immunodeficiency virus 1 infection
chx05200  Pathways in cancer
chx05203  Viral carcinogenesis
chx05416  Viral myocarditis
Brite
KEGG Orthology (KO) [BR:chx00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04668 TNF signaling pathway
    102169919 (CASP8)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    102169919 (CASP8)
   04215 Apoptosis - multiple species
    102169919 (CASP8)
   04217 Necroptosis
    102169919 (CASP8)
   04115 p53 signaling pathway
    102169919 (CASP8)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    102169919 (CASP8)
   04621 NOD-like receptor signaling pathway
    102169919 (CASP8)
   04622 RIG-I-like receptor signaling pathway
    102169919 (CASP8)
   04625 C-type lectin receptor signaling pathway
    102169919 (CASP8)
   04657 IL-17 signaling pathway
    102169919 (CASP8)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102169919 (CASP8)
   05203 Viral carcinogenesis
    102169919 (CASP8)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    102169919 (CASP8)
   05016 Huntington disease
    102169919 (CASP8)
   05022 Pathways of neurodegeneration - multiple diseases
    102169919 (CASP8)
  09166 Cardiovascular disease
   05416 Viral myocarditis
    102169919 (CASP8)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    102169919 (CASP8)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    102169919 (CASP8)
   05134 Legionellosis
    102169919 (CASP8)
   05152 Tuberculosis
    102169919 (CASP8)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    102169919 (CASP8)
   05161 Hepatitis B
    102169919 (CASP8)
   05160 Hepatitis C
    102169919 (CASP8)
   05164 Influenza A
    102169919 (CASP8)
   05162 Measles
    102169919 (CASP8)
   05168 Herpes simplex virus 1 infection
    102169919 (CASP8)
   05163 Human cytomegalovirus infection
    102169919 (CASP8)
   05167 Kaposi sarcoma-associated herpesvirus infection
    102169919 (CASP8)
   05169 Epstein-Barr virus infection
    102169919 (CASP8)
   05165 Human papillomavirus infection
    102169919 (CASP8)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    102169919 (CASP8)
   05142 Chagas disease
    102169919 (CASP8)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    102169919 (CASP8)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:chx01002]
    102169919 (CASP8)
Enzymes [BR:chx01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.61  caspase-8
     102169919 (CASP8)
Peptidases and inhibitors [BR:chx01002]
 Cysteine peptidases
  Family C14: caspase family
   102169919 (CASP8)
SSDB
Motif
Pfam: Peptidase_C14 DED AIG1
Other DBs
NCBI-GeneID: 102169919
NCBI-ProteinID: XP_005676421
UniProt: A0A452F8B6
LinkDB
Position
2
AA seq 488 aa
MDLTQCLYKIGEQLGSDDLAALKFLSRDHIPYRKQEPIKDALMLFQRLQEKRMLEESNLS
FLKELLFQVNRLDLLLNYLDTSEEEMKRELQIPGRAQISAYRILLFQISEDVNKVELKDF
KFFLSQEIAKCKLDDDMTLLDIFVEMEKRTILGENNLDTLKRICEQVNKSLLKKIYDYEE
LRKDSERIMRLERDPDEFSNDMSQSLPEQGSSEMLAMSDSPGEQGSELQTSDTVYRMTSK
PRGYCLIFNNYDFSIAREQVPELHSLKDRNGTHLDAEALDKTFRELHFEIVHYRDQTAKG
ICEVLKSYQKKDHKTKDCFICCILTHGNKGTIYGTDGQEAPIYELTSYFTGSKCPSLVGK
PKIFFIQACQGDKYQRGIAVETDSEQMEAYLEADSSPQKRYIPDEADFLLGMATVNNCVS
YRSILKGTWYIQSLCQNLRERCPRGEDILTILTKVNFEVSKKDDKQNMGKQMPQPTFTLR
KKLFFPLN
NT seq 1467 nt   +upstreamnt  +downstreamnt
atggatctcacccaatgtctctataaaattggagagcagctgggcagtgacgacctggct
gccctcaagttcctaagccgggaccacatcccatataggaagcaggaacccattaaggat
gccttgatgctattccagaggctccaagaaaagagaatgttggaggaaagcaatctgtcc
ttcttgaaggagctgcttttccaagtgaatagactggatctgctgcttaactacttggac
accagcgaggaggagatgaagagggagcttcagatacctggcagggcccagatctctgcc
tacaggatcctgcttttccagatttcagaagatgtgaacaaagtggaattgaaggacttt
aagttttttttgagccaggagattgccaaatgtaaactggatgatgacatgactttgctt
gatattttcgtggagatggagaagaggaccatcctaggggaaaataacttggacaccctg
aaaagaatctgtgagcaggtcaacaagagcttgctgaagaaaatctatgattatgaagaa
ttaagaaaagattcagagagaataatgagacttgaaagagatccagatgaattttcaaat
gacatgtcacaatcgcttccagagcagggctcctctgagatgctggccatgtcagactct
ccaggagaacagggcagtgagttgcagacatccgacacagtttaccgaatgacaagcaaa
cctcggggatactgtttgatctttaacaattatgattttagcatagcacgggagcaggtg
cccgaacttcacagccttaaggataggaatggaacacacttggatgcagaggctttggac
aagacctttcgtgaacttcattttgagatagtgcactacagagaccaaacagcaaaggga
atctgtgaggttctgaaatcctaccagaagaaggaccacaaaaccaaagactgcttcatc
tgctgcatcctcacccatggaaacaagggcaccatctatggcaccgatgggcaagaagcc
cccatctatgagctgacctcctacttcactggatcaaaatgcccttcccttgttggcaaa
cccaaaatcttttttattcaggcttgtcaaggggataagtaccagagaggaatagctgtt
gagaccgactcagaacagatggaagcctatttagaagcagattcatcacctcagaagaga
tatatcccagatgaggctgactttctgctggggatggccactgtgaacaactgtgtttcc
taccgaagcatcttgaaggggacctggtatatccaatcactttgtcagaacctgagagaa
agatgtcctaggggtgaagacattctgaccatcctaaccaaggtgaacttcgaagtaagc
aaaaaggatgacaagcaaaacatgggcaaacagatgccacaacctactttcacactgcga
aaaaaactcttctttcctcttaattga

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