KEGG   Capra hircus (goat): 102170356
Entry
102170356         CDS       T02910                                 

Gene name
GRB2
Definition
(RefSeq) growth factor receptor bound protein 2
  KO
K04364  growth factor receptor-bound protein 2
Organism
chx  Capra hircus (goat)
Pathway
chx01521  EGFR tyrosine kinase inhibitor resistance
chx01522  Endocrine resistance
chx04010  MAPK signaling pathway
chx04012  ErbB signaling pathway
chx04014  Ras signaling pathway
chx04062  Chemokine signaling pathway
chx04068  FoxO signaling pathway
chx04072  Phospholipase D signaling pathway
chx04150  mTOR signaling pathway
chx04151  PI3K-Akt signaling pathway
chx04380  Osteoclast differentiation
chx04510  Focal adhesion
chx04540  Gap junction
chx04550  Signaling pathways regulating pluripotency of stem cells
chx04630  JAK-STAT signaling pathway
chx04650  Natural killer cell mediated cytotoxicity
chx04660  T cell receptor signaling pathway
chx04662  B cell receptor signaling pathway
chx04664  Fc epsilon RI signaling pathway
chx04714  Thermogenesis
chx04722  Neurotrophin signaling pathway
chx04910  Insulin signaling pathway
chx04912  GnRH signaling pathway
chx04915  Estrogen signaling pathway
chx04917  Prolactin signaling pathway
chx04926  Relaxin signaling pathway
chx04935  Growth hormone synthesis, secretion and action
chx05034  Alcoholism
chx05160  Hepatitis C
chx05161  Hepatitis B
chx05163  Human cytomegalovirus infection
chx05165  Human papillomavirus infection
chx05200  Pathways in cancer
chx05203  Viral carcinogenesis
chx05205  Proteoglycans in cancer
chx05206  MicroRNAs in cancer
chx05210  Colorectal cancer
chx05211  Renal cell carcinoma
chx05213  Endometrial cancer
chx05214  Glioma
chx05215  Prostate cancer
chx05220  Chronic myeloid leukemia
chx05221  Acute myeloid leukemia
chx05223  Non-small cell lung cancer
chx05224  Breast cancer
chx05225  Hepatocellular carcinoma
chx05226  Gastric cancer
chx05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:chx00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102170356 (GRB2)
   04012 ErbB signaling pathway
    102170356 (GRB2)
   04014 Ras signaling pathway
    102170356 (GRB2)
   04630 JAK-STAT signaling pathway
    102170356 (GRB2)
   04068 FoxO signaling pathway
    102170356 (GRB2)
   04072 Phospholipase D signaling pathway
    102170356 (GRB2)
   04151 PI3K-Akt signaling pathway
    102170356 (GRB2)
   04150 mTOR signaling pathway
    102170356 (GRB2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    102170356 (GRB2)
   04540 Gap junction
    102170356 (GRB2)
   04550 Signaling pathways regulating pluripotency of stem cells
    102170356 (GRB2)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    102170356 (GRB2)
   04660 T cell receptor signaling pathway
    102170356 (GRB2)
   04662 B cell receptor signaling pathway
    102170356 (GRB2)
   04664 Fc epsilon RI signaling pathway
    102170356 (GRB2)
   04062 Chemokine signaling pathway
    102170356 (GRB2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    102170356 (GRB2)
   04912 GnRH signaling pathway
    102170356 (GRB2)
   04915 Estrogen signaling pathway
    102170356 (GRB2)
   04917 Prolactin signaling pathway
    102170356 (GRB2)
   04926 Relaxin signaling pathway
    102170356 (GRB2)
   04935 Growth hormone synthesis, secretion and action
    102170356 (GRB2)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    102170356 (GRB2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    102170356 (GRB2)
  09159 Environmental adaptation
   04714 Thermogenesis
    102170356 (GRB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102170356 (GRB2)
   05206 MicroRNAs in cancer
    102170356 (GRB2)
   05205 Proteoglycans in cancer
    102170356 (GRB2)
   05203 Viral carcinogenesis
    102170356 (GRB2)
   05231 Choline metabolism in cancer
    102170356 (GRB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    102170356 (GRB2)
   05225 Hepatocellular carcinoma
    102170356 (GRB2)
   05226 Gastric cancer
    102170356 (GRB2)
   05214 Glioma
    102170356 (GRB2)
   05221 Acute myeloid leukemia
    102170356 (GRB2)
   05220 Chronic myeloid leukemia
    102170356 (GRB2)
   05211 Renal cell carcinoma
    102170356 (GRB2)
   05215 Prostate cancer
    102170356 (GRB2)
   05213 Endometrial cancer
    102170356 (GRB2)
   05224 Breast cancer
    102170356 (GRB2)
   05223 Non-small cell lung cancer
    102170356 (GRB2)
  09165 Substance dependence
   05034 Alcoholism
    102170356 (GRB2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    102170356 (GRB2)
   05160 Hepatitis C
    102170356 (GRB2)
   05163 Human cytomegalovirus infection
    102170356 (GRB2)
   05165 Human papillomavirus infection
    102170356 (GRB2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    102170356 (GRB2)
   01522 Endocrine resistance
    102170356 (GRB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:chx04131]
    102170356 (GRB2)
  09183 Protein families: signaling and cellular processes
   04990 Domain-containing proteins not elsewhere classified [BR:chx04990]
    102170356 (GRB2)
Membrane trafficking [BR:chx04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Receptor tyrosine kinase (RTK) adaptor proteins
    102170356 (GRB2)
Domain-containing proteins not elsewhere classified [BR:chx04990]
 Src homology (SH) domain-containing proteins
  Signal transducing adaptor proteins
   102170356 (GRB2)
SSDB
Motif
Pfam: SH3_1 SH3_9 SH3_2 SH2 SH3_10 SH2_2 SH3_3 DUF5093 hSH3 SH3_4
Other DBs
NCBI-GeneID: 102170356
NCBI-ProteinID: XP_017919312
UniProt: A0A452ET74
LinkDB
Position
19
AA seq 217 aa
MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPW
FFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFL
WVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRG
DFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV
NT seq 654 nt   +upstreamnt  +downstreamnt
atggaagccatcgccaaatatgacttcaaagccaccgcagacgacgagctgagcttcaaa
aggggggacatcctcaaggttttgaatgaagaatgtgatcagaactggtacaaggcagag
ctcaatgggaaagacggcttcatccccaagaactacatagaaatgaaaccacatccgtgg
ttttttggcaaaatccccagagccaaagcagaagaaatgctcagcaaacagcggcatgat
ggggcctttcttatccgagagagcgagagtgctcctggggatttctccctctccgtcaag
tttggaaatgatgtacagcacttcaaggtgctccgagatggggctggaaagtatttcctc
tgggtggtcaagttcaactctttgaatgagctggtagattatcacagatctacatccgtc
tccagaaaccagcagatatttctccgggacatagagcaggtgccacagcagccgacatat
gtccaagccctctttgactttgacccccaggaggatggagagctgggattccgtcgggga
gactttatccacgtcatggataactcagaccccaactggtggaaaggggcttgccacggg
cagaccggcatgttcccacgcaattacgtcacccccgtgaaccggaacgtctaa

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