Capra hircus (goat): 102181262
Help
Entry
102181262 CDS
T02910
Gene name
CHUK
Definition
(RefSeq) conserved helix-loop-helix ubiquitous kinase
KO
K04467
inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:
2.7.11.10
]
Organism
chx
Capra hircus (goat)
Pathway
chx01523
Antifolate resistance
chx04010
MAPK signaling pathway
chx04014
Ras signaling pathway
chx04062
Chemokine signaling pathway
chx04064
NF-kappa B signaling pathway
chx04068
FoxO signaling pathway
chx04150
mTOR signaling pathway
chx04151
PI3K-Akt signaling pathway
chx04210
Apoptosis
chx04380
Osteoclast differentiation
chx04620
Toll-like receptor signaling pathway
chx04621
NOD-like receptor signaling pathway
chx04622
RIG-I-like receptor signaling pathway
chx04623
Cytosolic DNA-sensing pathway
chx04625
C-type lectin receptor signaling pathway
chx04657
IL-17 signaling pathway
chx04658
Th1 and Th2 cell differentiation
chx04659
Th17 cell differentiation
chx04660
T cell receptor signaling pathway
chx04662
B cell receptor signaling pathway
chx04668
TNF signaling pathway
chx04920
Adipocytokine signaling pathway
chx05010
Alzheimer disease
chx05132
Salmonella infection
chx05135
Yersinia infection
chx05142
Chagas disease
chx05145
Toxoplasmosis
chx05160
Hepatitis C
chx05161
Hepatitis B
chx05162
Measles
chx05163
Human cytomegalovirus infection
chx05164
Influenza A
chx05165
Human papillomavirus infection
chx05166
Human T-cell leukemia virus 1 infection
chx05167
Kaposi sarcoma-associated herpesvirus infection
chx05168
Herpes simplex virus 1 infection
chx05169
Epstein-Barr virus infection
chx05170
Human immunodeficiency virus 1 infection
chx05171
Coronavirus disease - COVID-19
chx05200
Pathways in cancer
chx05212
Pancreatic cancer
chx05215
Prostate cancer
chx05220
Chronic myeloid leukemia
chx05221
Acute myeloid leukemia
chx05222
Small cell lung cancer
chx05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
chx05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
chx00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102181262 (CHUK)
04014 Ras signaling pathway
102181262 (CHUK)
04064 NF-kappa B signaling pathway
102181262 (CHUK)
04668 TNF signaling pathway
102181262 (CHUK)
04068 FoxO signaling pathway
102181262 (CHUK)
04151 PI3K-Akt signaling pathway
102181262 (CHUK)
04150 mTOR signaling pathway
102181262 (CHUK)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
102181262 (CHUK)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
102181262 (CHUK)
04621 NOD-like receptor signaling pathway
102181262 (CHUK)
04622 RIG-I-like receptor signaling pathway
102181262 (CHUK)
04623 Cytosolic DNA-sensing pathway
102181262 (CHUK)
04625 C-type lectin receptor signaling pathway
102181262 (CHUK)
04660 T cell receptor signaling pathway
102181262 (CHUK)
04658 Th1 and Th2 cell differentiation
102181262 (CHUK)
04659 Th17 cell differentiation
102181262 (CHUK)
04657 IL-17 signaling pathway
102181262 (CHUK)
04662 B cell receptor signaling pathway
102181262 (CHUK)
04062 Chemokine signaling pathway
102181262 (CHUK)
09152 Endocrine system
04920 Adipocytokine signaling pathway
102181262 (CHUK)
09158 Development and regeneration
04380 Osteoclast differentiation
102181262 (CHUK)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102181262 (CHUK)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
102181262 (CHUK)
09162 Cancer: specific types
05212 Pancreatic cancer
102181262 (CHUK)
05221 Acute myeloid leukemia
102181262 (CHUK)
05220 Chronic myeloid leukemia
102181262 (CHUK)
05215 Prostate cancer
102181262 (CHUK)
05222 Small cell lung cancer
102181262 (CHUK)
09164 Neurodegenerative disease
05010 Alzheimer disease
102181262 (CHUK)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
102181262 (CHUK)
09171 Infectious disease: bacterial
05132 Salmonella infection
102181262 (CHUK)
05135 Yersinia infection
102181262 (CHUK)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
102181262 (CHUK)
05170 Human immunodeficiency virus 1 infection
102181262 (CHUK)
05161 Hepatitis B
102181262 (CHUK)
05160 Hepatitis C
102181262 (CHUK)
05171 Coronavirus disease - COVID-19
102181262 (CHUK)
05164 Influenza A
102181262 (CHUK)
05162 Measles
102181262 (CHUK)
05168 Herpes simplex virus 1 infection
102181262 (CHUK)
05163 Human cytomegalovirus infection
102181262 (CHUK)
05167 Kaposi sarcoma-associated herpesvirus infection
102181262 (CHUK)
05169 Epstein-Barr virus infection
102181262 (CHUK)
05165 Human papillomavirus infection
102181262 (CHUK)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
102181262 (CHUK)
05142 Chagas disease
102181262 (CHUK)
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
102181262 (CHUK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
chx01001
]
102181262 (CHUK)
Enzymes [BR:
chx01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.10 IkappaB kinase
102181262 (CHUK)
Protein kinases [BR:
chx01001
]
Serine/threonine kinases: Other
IKK family [OT]
102181262 (CHUK)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
IKBKB_SDD
Pkinase
PK_Tyr_Ser-Thr
IKKbetaNEMObind
Pkinase_fungal
Kdo
TBK1_ULD
Motif
Other DBs
NCBI-GeneID:
102181262
NCBI-ProteinID:
XP_017896836
UniProt:
A0A452EYD5
LinkDB
All DBs
Position
26
AA seq
740 aa
AA seq
DB search
MERPPGLRPGAGGPWEMRERLGTGGFGNVCLYQHRELDLKIAIKSCRLELSTKNRERWCH
EIQIMKKLNHANVVKACDVPEELNFLINDVPLLAMEYCSGGDLRKLLNKPENCCGLKESQ
ILSLLSDIGSGIRYLHENKIIHRDLKPENIVLQDVGGKIMHKIIDLGYAKDVDQGSLCTS
FVGTLQYLAPELFENKPYTATVDYWSFGTMVFECIAGYRPFLHHLQPFTWHEKIKKKDPK
CIFACEEMTGEVRFSSHLPQPNSLCSLIVEPMENWLQLMLNWDPQQRGGPVDLTLKQPRC
FVLMDHILNLKIVHILNMTSAKIISFLLPPDESLHSLQSRIERETGINTGSQELLSEMGI
SLDPRKPASQCVLDGVRGCDSYMVYLFDKSKTVYEGPFASRSLSDCVNYIVQDSKIQLPI
IQLRKVWAEAVHYVSGLKEDYSRLFQGQRAAMLSLLRYNTNLTKMKNTLISASQQLKAKL
EFFHKSIQLDLERYSEQMTYGISSEKMLKAWKEMEEKAIHYAEVGVIGYLEDQIMSLHTE
IMELQKSPYGRRQGDLMESLEQRAIDLYKQLKHRPSDHSYSDSTEMVKIIVHTVQSQDRV
LKELFGHLSKLLGCKQKIIDLLPKVEMALSNIKEADNTVMFMQGKRQKEIWHLLKIACTQ
SSARSLVGSSLEGVTPQLPPTSAEREHPLSCVVTPQDGETLAQMIEENLNCLGHLSTIIH
EANEKQGDSMMSLDWSWLTE
NT seq
2223 nt
NT seq
+upstream
nt +downstream
nt
atggagcggcccccggggctgcggccgggcgcgggcgggccctgggagatgcgggagcgg
ctgggcaccggtggcttcgggaacgtctgcctgtatcaacatcgggaacttgatctcaaa
atagcaattaagtcttgtcgcctagagctaagtaccaaaaacagagaacggtggtgccat
gaaatccagatcatgaagaagttgaaccacgccaatgttgtaaaggcctgtgacgttcct
gaggaattgaattttttgattaacgatgtgcctcttctagcaatggaatattgttctgga
ggagatctccggaagctactcaacaaaccagaaaattgctgtggacttaaagaaagccag
atactttctttactgagtgatataggatctgggatccgatatttgcatgaaaacaaaatt
atacatcgtgatctaaaacctgaaaacatagttcttcaggatgttggcggaaagattatg
cataaaataattgatttgggatatgccaaagatgttgatcaaggaagtctttgtacatct
tttgtgggaactttgcagtatctggccccagagctctttgagaataagccttatacagcc
actgttgattattggagctttgggaccatggtgtttgaatgtattgctggatataggcct
tttttgcatcatctgcagccatttacttggcatgagaagattaagaagaaggatccaaag
tgtatatttgcatgtgaagaaatgacaggagaagttcggtttagtagccatttacctcaa
ccaaatagcctttgtagtttaatagtagaacccatggaaaactggctgcagttgatgcta
aactgggatcctcagcagagaggaggacctgttgatcttactttgaagcagccaagatgt
tttgtattaatggatcacattctgaatttgaagatagtacatatcctaaatatgacttct
gcaaagataatttcttttctgttaccacctgatgaaagtcttcattcactacagtctcgt
attgagcgggaaactggaataaatactggttctcaagagcttctttcagagatgggaatt
tctctggatcctcggaaaccagcctctcagtgtgttctggatggagttaggggctgtgat
agctatatggtttatttgtttgataaaagtaagactgtatatgaaggaccatttgcttcc
agaagtttatctgactgtgtaaattatattgtacaggacagcaaaatacagcttccaatt
atccagttgcgtaaagtttgggctgaagcagtacactatgtgtctgggctgaaagaagac
tacagcaggctctttcagggacagagagcagccatgttaagccttcttagatacaatact
aacttgacaaaaatgaaaaacactttgatctcagcatctcagcaactgaaagctaaattg
gagttttttcacaaaagcattcagcttgacttggaaagatatagtgagcagatgacgtac
gggatatcctcagaaaaaatgttaaaagcttggaaagaaatggaagaaaaggctatccac
tatgctgaggtgggtgtcattggatacctggaggatcaaatcatgtccctgcacactgaa
atcatggagctacagaagagcccctatggacgacgtcagggagacttgatggaatctctg
gaacagcgtgcaattgatctatataagcagttaaagcacagaccttcagatcactcctac
agcgacagcacggagatggtgaaaatcattgtgcatactgtgcagagtcaggaccgggtt
ctcaaggagctgtttggtcatctgagcaagttgttgggctgtaagcagaagattattgat
ctactgcccaaggtggaaatggccctcagtaacatcaaagaagctgacaatactgtcatg
tttatgcagggaaagaggcagaaagaaatatggcatctccttaaaattgcctgtacacag
agttctgctcggtcccttgtaggatccagtctagaaggtgtaacccctcagctgccccca
acttcagcagaacgtgaacatcctctgtcatgcgtggtaactcctcaagatggggagact
ttagcacaaatgatagaagaaaatttgaactgtcttggccatttaagcactattattcat
gaagcaaatgaaaaacagggcgacagtatgatgagtcttgattggagttggttaacagaa
tga
DBGET
integrated database retrieval system
