KEGG   Capra hircus (goat): 102181474
Entry
102181474         CDS       T02910                                 

Gene name
TBK1, NAK, T2K
Definition
(RefSeq) TANK binding kinase 1
  KO
K05410  TANK-binding kinase 1 [EC:2.7.11.10]
Organism
chx  Capra hircus (goat)
Pathway
chx04014  Ras signaling pathway
chx04137  Mitophagy - animal
chx04140  Autophagy - animal
chx04620  Toll-like receptor signaling pathway
chx04621  NOD-like receptor signaling pathway
chx04622  RIG-I-like receptor signaling pathway
chx04623  Cytosolic DNA-sensing pathway
chx04657  IL-17 signaling pathway
chx05014  Amyotrophic lateral sclerosis
chx05022  Pathways of neurodegeneration - multiple diseases
chx05135  Yersinia infection
chx05160  Hepatitis C
chx05161  Hepatitis B
chx05162  Measles
chx05163  Human cytomegalovirus infection
chx05164  Influenza A
chx05165  Human papillomavirus infection
chx05167  Kaposi sarcoma-associated herpesvirus infection
chx05168  Herpes simplex virus 1 infection
chx05169  Epstein-Barr virus infection
chx05170  Human immunodeficiency virus 1 infection
chx05171  Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:chx00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    102181474 (TBK1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    102181474 (TBK1)
   04137 Mitophagy - animal
    102181474 (TBK1)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    102181474 (TBK1)
   04621 NOD-like receptor signaling pathway
    102181474 (TBK1)
   04622 RIG-I-like receptor signaling pathway
    102181474 (TBK1)
   04623 Cytosolic DNA-sensing pathway
    102181474 (TBK1)
   04657 IL-17 signaling pathway
    102181474 (TBK1)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    102181474 (TBK1)
   05022 Pathways of neurodegeneration - multiple diseases
    102181474 (TBK1)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    102181474 (TBK1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    102181474 (TBK1)
   05161 Hepatitis B
    102181474 (TBK1)
   05160 Hepatitis C
    102181474 (TBK1)
   05171 Coronavirus disease - COVID-19
    102181474 (TBK1)
   05164 Influenza A
    102181474 (TBK1)
   05162 Measles
    102181474 (TBK1)
   05168 Herpes simplex virus 1 infection
    102181474 (TBK1)
   05163 Human cytomegalovirus infection
    102181474 (TBK1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    102181474 (TBK1)
   05169 Epstein-Barr virus infection
    102181474 (TBK1)
   05165 Human papillomavirus infection
    102181474 (TBK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:chx01001]
    102181474 (TBK1)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:chx04131]
    102181474 (TBK1)
Enzymes [BR:chx01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.10  IkappaB kinase
     102181474 (TBK1)
Protein kinases [BR:chx01001]
 Serine/threonine kinases: Other
  IKK family [OT]
   102181474 (TBK1)
Membrane trafficking [BR:chx04131]
 Autophagy
  Xenophagy
   Other xenophagy associated proteins
    102181474 (TBK1)
SSDB
Motif
Pfam: TBK1_CCD1 Pkinase TBK1_ULD PK_Tyr_Ser-Thr Pkinase_fungal Kinase-like DUF713 CEP63
Other DBs
NCBI-GeneID: 102181474
NCBI-ProteinID: XP_017903478
LinkDB
Position
5
AA seq 729 aa
MQSTSNHLWLLSDVLGQGATANVFRGRHKKTGDLFAIKVFNNISFLRPVDVQMREFEVLK
KLNHKNIVKLFAIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVV
GGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYGTEEYL
HPDMYERAVLRKDHQKKYGATVDLWSIGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITG
KPSGAISGVQKAENGPIDWSGDMPVSCSLSRGLQVLLTPVLANILEADQEKCWGFDQFFA
ETSDILHRMIVHVFSLQQMTAHKIYIHGYNTATVFHELVYKQTKIISSNQELIYEGRRLV
LEPGRLAQHFPKTSEENPIFVVSREPLSTIGLIYEKISLPKVHPRYDLDGDASMAKAMTG
VVCYACRIASTLLLYQELMRKGIRWLIELVKDDYNETVHKKTEVVITLDFCIRNIEKTMK
VYEKLMKINIEAAELGEISDIRTKLLRLSSSQGTIETSLQDIESKLSPGGLLADTWTHQE
GTHPKDRHVEKLQVLLNCITEIYYQFKKDKAERRLAYNEEQIHKFDKQKLYYHATKAMTH
FTDECVKKYEAFLDKSEEWMRKMLHLRKQLLSLTNQCFDIEEEVSKYQDYTNELQETLPQ
KMFAASSGIKHTMTPIYPCSNTLVEMTLGMKKLKEEMEGVVKELAENNHILERFGSLTMD
GGLRNVDCL
NT seq 2190 nt   +upstreamnt  +downstreamnt
atgcagagcacttctaatcatctgtggcttttatctgatgttttaggccaaggagctact
gcaaatgtctttcgtggaagacataagaaaactggtgacttatttgctatcaaagtattt
aataacataagcttccttcgtccagtggatgttcaaatgagagaatttgaagtgttaaaa
aaactgaatcacaaaaacattgtcaaattatttgctattgaagaagagacaacaacaaga
cataaagtacttattatggaattttgcccatgtgggagtttatacactgttttagaagaa
ccatctaatgcctatggactaccagagtctgagtttctaattgttttgcgagatgtggtg
ggtggaatgaatcatctccgagagaatggcatagttcaccgtgatatcaagccaggaaat
atcatgcgtgtgataggggaagacggacagtctgtgtacaaactcacagattttggtgca
gctagagaattagaagatgatgagcagtttgtttctctgtatggcacagaagaatatttg
catcctgatatgtatgagagagcggtgctaagaaaagatcatcagaagaaatacggagca
actgtggatctttggagcattggggtaacattttaccatgcagctactggatcactgcca
tttagaccatttgaagggccacgtaggaataaggaagtgatgtataaaataattactgga
aagccttctggtgcaatatctggagtacagaaagcagaaaatggaccaattgactggagt
ggagacatgcctgtttcttgtagtctttctcggggtcttcaagttctgcttactcctgtt
cttgcaaacatccttgaggcagatcaggaaaagtgttggggttttgaccagttttttgca
gaaactagtgatatacttcaccggatgatagttcatgttttttcactacaacaaatgaca
gctcataaaatttatattcatggctataatactgctactgtatttcatgaactggtatat
aaacaaaccaaaattatttcttcaaatcaagagcttatatatgaaggacgacgtttagtt
ctagaacctggaagactggcacagcatttccctaaaacttctgaggaaaaccctatcttc
gtagtaagccgggaacctctgagtaccataggattgatatatgaaaaaatttccctccct
aaagtacatccacgttatgatttagatggggatgccagcatggctaaggcaatgacagga
gttgtgtgttatgcctgtagaattgccagtaccttgctgctttatcaggaattaatgcgg
aaggggatacgatggttgatagaattagttaaagatgactataatgaaactgttcacaaa
aagacagaagttgtgatcacgttggatttctgcatcagaaacattgaaaaaactatgaaa
gtatatgaaaagttgatgaagatcaacatagaagcagcagagttaggtgaaatttcagac
atacgcaccaagctgttgagactttccagttctcagggaacaatagaaaccagtctccag
gatattgaaagcaaattgtctccaggtggattacttgccgatacatggacccatcaagaa
ggcactcatcccaaagatagacatgtagaaaagctacaagtcctgttaaattgcatcaca
gagatttactatcagttcaaaaaagacaaagcagaacgtagactagcttataatgaagaa
caaatccacaaatttgataagcaaaaactgtattatcatgcaacaaaagctatgacccac
tttacggatgaatgtgttaaaaagtatgaggctttcttggataagtcagaagaatggatg
agaaagatgcttcaccttaggaaacagttattatccctaactaatcagtgttttgatatt
gaagaagaagtatcgaagtatcaagactatactaatgagttacaagaaactttgccacag
aaaatgttcgcagcctccagtggaatcaaacataccatgaccccaatttatccatgttct
aacacattagtagaaatgactcttggtatgaagaaattaaaggaagaaatggaaggagta
gttaaagaacttgctgaaaataatcatattttagaaaggtttggctcattaaccatggac
ggcggcctccgcaatgtcgactgtctttag

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