KEGG   Capra hircus (goat): 102189319
Entry
102189319         CDS       T02910                                 

Gene name
FLT3
Definition
(RefSeq) fms related tyrosine kinase 3
  KO
K05092  fms-related tyrosine kinase 3 [EC:2.7.10.1]
Organism
chx  Capra hircus (goat)
Pathway
chx04010  MAPK signaling pathway
chx04014  Ras signaling pathway
chx04151  PI3K-Akt signaling pathway
chx04640  Hematopoietic cell lineage
chx05200  Pathways in cancer
chx05202  Transcriptional misregulation in cancer
chx05221  Acute myeloid leukemia
chx05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:chx00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102189319 (FLT3)
   04014 Ras signaling pathway
    102189319 (FLT3)
   04151 PI3K-Akt signaling pathway
    102189319 (FLT3)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    102189319 (FLT3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102189319 (FLT3)
   05202 Transcriptional misregulation in cancer
    102189319 (FLT3)
   05230 Central carbon metabolism in cancer
    102189319 (FLT3)
  09162 Cancer: specific types
   05221 Acute myeloid leukemia
    102189319 (FLT3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:chx01001]
    102189319 (FLT3)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:chx04090]
    102189319 (FLT3)
Enzymes [BR:chx01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     102189319 (FLT3)
Protein kinases [BR:chx01001]
 Receptor tyrosine kinases (RTK)
  PDGFR family [OT]
   102189319 (FLT3)
CD molecules [BR:chx04090]
 Proteins
  102189319 (FLT3)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase ig Ig_3 I-set Ig_2 APH
Other DBs
NCBI-GeneID: 102189319
NCBI-ProteinID: XP_017912082
UniProt: A0A452DSQ2
LinkDB
Position
12
AA seq 992 aa
MPALARLGGRLPLLVFSAMIFQTVTNQDLPEIKCVLINHGNNDSSMGTSSSNPMASESRE
DLACALRPEGSETIYEAATVQVDVAASITLQVLVSAPGNTSCLWVFKHSYLNCQPHFDLQ
NRGVFSMVILKMTETQAGEYRLLIQSAATNYTVLFTVSIRSTLLYTLRKPYFRKMENQDA
LVCISESVPEPTVEWVFCDSQSDSCKGESPAVVTKEESVLHELFGTDIRCCARNELGREC
TKLFTIDLNQTPQTTPPQLFLKVGEPLWIRCKAIHVNHGFGLSWELENKALEEGSYFEMS
TYSTNRTMIRILFAFVSSVGRNDTGYYTCSSSEHPSKSALVTILEKGFINVSKSNEDYEI
DQYEEFCFSVRFKAYPQIRCTWTFSRKSFPCEQSGLDDGYSISKFCNHKHQPGQYIFHAE
NDDAQFTKEFTLNIRRKPQVLAEASASQASCSSDGYPIPSWTWKKCSDKSPNCTEEITEG
IWNKKANKKVFGQWISSSTLNMSEAVKGFLVKCCAYNALGMSCETILLSSPGPFPSIQDN
ISFYATIGLCLPFIAVLTMLICHKYKKQFRYESQLQMVQVTGSLDNEYFYVDFREYEYDL
KWEFPRENLEFGKVLGSGAFGKVMNATAYGISKTGVSIQVAVKMLKEKADSSEREALMSE
LKMMTHLGSHENIVNLLGACTLSGPIYLIFEYCCYGDLLNYLRSKREKFHRTWTEIFKEH
NFSFYPTFQSHPNSSMPGSREVQIHPDSDPISGFNGNSFQSEDEIEYENQKRLEEEEDLN
VLTFEDLLCFAYQVAKGMEFLEFKSCLHRDLAARNVLVTHGKVAKIADFGLARDIMSDSN
YVIRGNARLPVKWMAPESLFEGIYTIKSDVWSYGILLWEIFSLGVNPYPGIPADANFYKL
IQSGFKMDQPFYATEEIYFIMQSCWAFDSRKRPSFPNLTSFLGCQLADAEEAMYQNLDGR
VSERPSVYQNRRPYSREVDLGLPSPQVHTEDS
NT seq 2979 nt   +upstreamnt  +downstreamnt
atgccggcgttggcgcgcctgggcggccggctgccgctgctcgttttttccgcaatgata
ttccagactgttacaaatcaagatctgcctgagatcaagtgtgttttaatcaaccatgga
aacaatgattcatcaatggggacatcatcttcgaatcccatggcatcagaatcccgggaa
gacctggcgtgtgccttgaggcccgagggctcagagaccatctacgaagcggccactgtg
caggtggacgtggctgcctccatcacactgcaagtgctggtctccgccccagggaacact
tcctgtctctgggtctttaaacacagctacctaaactgccagccacacttcgatttacaa
aacagaggagttttttccatggtcattttgaaaatgacagaaacccaagctggagaatac
cgacttttgattcagagtgcagctaccaattacacagtattgtttacagtgagtataaga
agtacactgctttacacgttaagaaaaccttactttagaaaaatggaaaatcaggacgcc
ttggtctgcatctcagagagtgttccagaaccgacggtggaatgggtgttctgcgattca
cagagtgacagctgtaaaggagagagtccagctgtcgtcacgaaggaggagagcgtcctc
catgagttatttggaacagatatcaggtgctgtgcaagaaatgagctgggcagggaatgt
accaagctcttcactatagatctaaaccagactcctcagaccacaccgccacaattattt
cttaaagtaggggaacctttatggataaggtgcaaagccattcacgtaaaccatggattc
gggctcagctgggaattagagaataaagcactggaagagggcagctactttgagatgagt
acctattccacaaacagaactatgatacggattctgtttgcttttgtatcatcagtggga
agaaacgacactggctattacacttgttcctcttcagagcatcccagtaaatcagctttg
gtcaccatcctagaaaagggatttataaatgtttccaaatcaaatgaagattatgaaatt
gaccagtatgaagagttttgtttttctgtcaggtttaaagcatacccacaaatcagatgt
acgtggaccttctctcgaaaatcatttccttgtgagcaaagtggtctggatgatgggtac
agcatatctaagttttgcaaccataaacaccagccaggacagtatatcttccatgcagaa
aatgatgacgcccagttcaccaaagagttcacactgaatataagaaggaaacctcaagtg
ctggctgaggcatctgcaagtcaggcttcttgctcctctgatgggtaccctataccatcc
tggacctggaagaagtgctcagacaagtcccccaactgcacagaagaaatcacagaagga
atttggaataaaaaggccaacaagaaagtgtttggacagtggatatcgagcagcacgctg
aacatgagtgaggccgtcaaagggttcctggtgaagtgttgtgcctacaatgcccttggc
atgtcctgtgagacaatccttctgagctcaccagggcccttcccttccatccaggacaac
atctcattctatgcgacaattggcctctgtcttcccttcatcgccgttttaaccatgctg
atttgtcacaagtacaaaaagcaatttcgttacgaaagccagctgcagatggtgcaggtg
accggctctctggataacgagtacttctacgttgacttcagagaatatgagtatgatctc
aaatgggagtttccgagagaaaacttggaatttgggaaggtcctggggtcgggtgctttt
ggaaaagtgatgaatgcgaccgcctacggaattagtaaaacaggggtctccatccaggtc
gcagtcaagatgctgaaagagaaagcagacagctcggagagagaggcgctcatgtctgaa
ctcaaaatgatgacccacctgggcagccacgagaatatcgtgaatctcctgggggcgtgc
accctgtcaggaccaatttacttgatttttgaatactgttgctacggtgaccttctcaac
tatctaagaagtaaaagagaaaaatttcacaggacgtggacggagattttcaaggaacat
aatttcagtttttatcccactttccaatcacaccctaattccagtatgccgggttcaaga
gaagttcaaatacacccggactcagatcctatctcagggttcaatgggaattcatttcag
tctgaagatgaaattgaatacgaaaaccaaaaaaggctggaggaagaagaagacctgaat
gtactgacctttgaagatctcctttgctttgcatatcaagtggccaaaggaatggaattt
ctggaatttaagtcgtgtcttcacagagacctggcagccaggaatgtcctggtgacccat
gggaaagtggcgaagatcgctgattttgggctggctcgggatattatgagtgattccaac
tacgtcatcaggggaaatgcccgtctgcctgtgaagtggatggctcctgaaagcttgttt
gagggcatctacacaattaaaagcgatgtctggtcatacggaatattactctgggaaata
ttctcgcttggtgtcaatccttaccctgggattccggctgatgctaacttctacaaactc
atccagagtgggttcaagatggaccagccattttatgccacagaagaaatatactttata
atgcaatcctgctgggcttttgactccaggaaacgaccatccttccctaacctgacttca
tttttagggtgtcagctggcagatgcagaagaagcgatgtatcagaacttggatggccgt
gtttcagagcgtccttctgtttaccaaaacaggcgaccttacagcagagaggtggacttg
gggctaccctctcctcaggttcacactgaagattcctag

DBGET integrated database retrieval system