Capra hircus (goat): 102189319
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Entry
102189319 CDS
T02910
Gene name
FLT3
Definition
(RefSeq) fms related tyrosine kinase 3
KO
K05092
fms-related tyrosine kinase 3 [EC:
2.7.10.1
]
Organism
chx
Capra hircus (goat)
Pathway
chx04010
MAPK signaling pathway
chx04014
Ras signaling pathway
chx04151
PI3K-Akt signaling pathway
chx04640
Hematopoietic cell lineage
chx05200
Pathways in cancer
chx05202
Transcriptional misregulation in cancer
chx05221
Acute myeloid leukemia
chx05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
chx00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102189319 (FLT3)
04014 Ras signaling pathway
102189319 (FLT3)
04151 PI3K-Akt signaling pathway
102189319 (FLT3)
09150 Organismal Systems
09151 Immune system
04640 Hematopoietic cell lineage
102189319 (FLT3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102189319 (FLT3)
05202 Transcriptional misregulation in cancer
102189319 (FLT3)
05230 Central carbon metabolism in cancer
102189319 (FLT3)
09162 Cancer: specific types
05221 Acute myeloid leukemia
102189319 (FLT3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
chx01001
]
102189319 (FLT3)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
chx04090
]
102189319 (FLT3)
Enzymes [BR:
chx01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
102189319 (FLT3)
Protein kinases [BR:
chx01001
]
Receptor tyrosine kinases (RTK)
PDGFR family [OT]
102189319 (FLT3)
CD molecules [BR:
chx04090
]
Proteins
102189319 (FLT3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
ig
Ig_3
I-set
Ig_2
APH
Motif
Other DBs
NCBI-GeneID:
102189319
NCBI-ProteinID:
XP_017912082
UniProt:
A0A452DSQ2
LinkDB
All DBs
Position
12
AA seq
992 aa
AA seq
DB search
MPALARLGGRLPLLVFSAMIFQTVTNQDLPEIKCVLINHGNNDSSMGTSSSNPMASESRE
DLACALRPEGSETIYEAATVQVDVAASITLQVLVSAPGNTSCLWVFKHSYLNCQPHFDLQ
NRGVFSMVILKMTETQAGEYRLLIQSAATNYTVLFTVSIRSTLLYTLRKPYFRKMENQDA
LVCISESVPEPTVEWVFCDSQSDSCKGESPAVVTKEESVLHELFGTDIRCCARNELGREC
TKLFTIDLNQTPQTTPPQLFLKVGEPLWIRCKAIHVNHGFGLSWELENKALEEGSYFEMS
TYSTNRTMIRILFAFVSSVGRNDTGYYTCSSSEHPSKSALVTILEKGFINVSKSNEDYEI
DQYEEFCFSVRFKAYPQIRCTWTFSRKSFPCEQSGLDDGYSISKFCNHKHQPGQYIFHAE
NDDAQFTKEFTLNIRRKPQVLAEASASQASCSSDGYPIPSWTWKKCSDKSPNCTEEITEG
IWNKKANKKVFGQWISSSTLNMSEAVKGFLVKCCAYNALGMSCETILLSSPGPFPSIQDN
ISFYATIGLCLPFIAVLTMLICHKYKKQFRYESQLQMVQVTGSLDNEYFYVDFREYEYDL
KWEFPRENLEFGKVLGSGAFGKVMNATAYGISKTGVSIQVAVKMLKEKADSSEREALMSE
LKMMTHLGSHENIVNLLGACTLSGPIYLIFEYCCYGDLLNYLRSKREKFHRTWTEIFKEH
NFSFYPTFQSHPNSSMPGSREVQIHPDSDPISGFNGNSFQSEDEIEYENQKRLEEEEDLN
VLTFEDLLCFAYQVAKGMEFLEFKSCLHRDLAARNVLVTHGKVAKIADFGLARDIMSDSN
YVIRGNARLPVKWMAPESLFEGIYTIKSDVWSYGILLWEIFSLGVNPYPGIPADANFYKL
IQSGFKMDQPFYATEEIYFIMQSCWAFDSRKRPSFPNLTSFLGCQLADAEEAMYQNLDGR
VSERPSVYQNRRPYSREVDLGLPSPQVHTEDS
NT seq
2979 nt
NT seq
+upstream
nt +downstream
nt
atgccggcgttggcgcgcctgggcggccggctgccgctgctcgttttttccgcaatgata
ttccagactgttacaaatcaagatctgcctgagatcaagtgtgttttaatcaaccatgga
aacaatgattcatcaatggggacatcatcttcgaatcccatggcatcagaatcccgggaa
gacctggcgtgtgccttgaggcccgagggctcagagaccatctacgaagcggccactgtg
caggtggacgtggctgcctccatcacactgcaagtgctggtctccgccccagggaacact
tcctgtctctgggtctttaaacacagctacctaaactgccagccacacttcgatttacaa
aacagaggagttttttccatggtcattttgaaaatgacagaaacccaagctggagaatac
cgacttttgattcagagtgcagctaccaattacacagtattgtttacagtgagtataaga
agtacactgctttacacgttaagaaaaccttactttagaaaaatggaaaatcaggacgcc
ttggtctgcatctcagagagtgttccagaaccgacggtggaatgggtgttctgcgattca
cagagtgacagctgtaaaggagagagtccagctgtcgtcacgaaggaggagagcgtcctc
catgagttatttggaacagatatcaggtgctgtgcaagaaatgagctgggcagggaatgt
accaagctcttcactatagatctaaaccagactcctcagaccacaccgccacaattattt
cttaaagtaggggaacctttatggataaggtgcaaagccattcacgtaaaccatggattc
gggctcagctgggaattagagaataaagcactggaagagggcagctactttgagatgagt
acctattccacaaacagaactatgatacggattctgtttgcttttgtatcatcagtggga
agaaacgacactggctattacacttgttcctcttcagagcatcccagtaaatcagctttg
gtcaccatcctagaaaagggatttataaatgtttccaaatcaaatgaagattatgaaatt
gaccagtatgaagagttttgtttttctgtcaggtttaaagcatacccacaaatcagatgt
acgtggaccttctctcgaaaatcatttccttgtgagcaaagtggtctggatgatgggtac
agcatatctaagttttgcaaccataaacaccagccaggacagtatatcttccatgcagaa
aatgatgacgcccagttcaccaaagagttcacactgaatataagaaggaaacctcaagtg
ctggctgaggcatctgcaagtcaggcttcttgctcctctgatgggtaccctataccatcc
tggacctggaagaagtgctcagacaagtcccccaactgcacagaagaaatcacagaagga
atttggaataaaaaggccaacaagaaagtgtttggacagtggatatcgagcagcacgctg
aacatgagtgaggccgtcaaagggttcctggtgaagtgttgtgcctacaatgcccttggc
atgtcctgtgagacaatccttctgagctcaccagggcccttcccttccatccaggacaac
atctcattctatgcgacaattggcctctgtcttcccttcatcgccgttttaaccatgctg
atttgtcacaagtacaaaaagcaatttcgttacgaaagccagctgcagatggtgcaggtg
accggctctctggataacgagtacttctacgttgacttcagagaatatgagtatgatctc
aaatgggagtttccgagagaaaacttggaatttgggaaggtcctggggtcgggtgctttt
ggaaaagtgatgaatgcgaccgcctacggaattagtaaaacaggggtctccatccaggtc
gcagtcaagatgctgaaagagaaagcagacagctcggagagagaggcgctcatgtctgaa
ctcaaaatgatgacccacctgggcagccacgagaatatcgtgaatctcctgggggcgtgc
accctgtcaggaccaatttacttgatttttgaatactgttgctacggtgaccttctcaac
tatctaagaagtaaaagagaaaaatttcacaggacgtggacggagattttcaaggaacat
aatttcagtttttatcccactttccaatcacaccctaattccagtatgccgggttcaaga
gaagttcaaatacacccggactcagatcctatctcagggttcaatgggaattcatttcag
tctgaagatgaaattgaatacgaaaaccaaaaaaggctggaggaagaagaagacctgaat
gtactgacctttgaagatctcctttgctttgcatatcaagtggccaaaggaatggaattt
ctggaatttaagtcgtgtcttcacagagacctggcagccaggaatgtcctggtgacccat
gggaaagtggcgaagatcgctgattttgggctggctcgggatattatgagtgattccaac
tacgtcatcaggggaaatgcccgtctgcctgtgaagtggatggctcctgaaagcttgttt
gagggcatctacacaattaaaagcgatgtctggtcatacggaatattactctgggaaata
ttctcgcttggtgtcaatccttaccctgggattccggctgatgctaacttctacaaactc
atccagagtgggttcaagatggaccagccattttatgccacagaagaaatatactttata
atgcaatcctgctgggcttttgactccaggaaacgaccatccttccctaacctgacttca
tttttagggtgtcagctggcagatgcagaagaagcgatgtatcagaacttggatggccgt
gtttcagagcgtccttctgtttaccaaaacaggcgaccttacagcagagaggtggacttg
gggctaccctctcctcaggttcacactgaagattcctag
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