KEGG T03264: 100385604

KEGG Orthology (KO) [BR:cjc00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    100385604 (CDK6)
09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    100385604 (CDK6)
   04115 p53 signaling pathway
    100385604 (CDK6)
   04218 Cellular senescence
    100385604 (CDK6)
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100385604 (CDK6)
   05206 MicroRNAs in cancer
    100385604 (CDK6)
   05203 Viral carcinogenesis
    100385604 (CDK6)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    100385604 (CDK6)
   05225 Hepatocellular carcinoma
    100385604 (CDK6)
   05214 Glioma
    100385604 (CDK6)
   05220 Chronic myeloid leukemia
    100385604 (CDK6)
   05218 Melanoma
    100385604 (CDK6)
   05224 Breast cancer
    100385604 (CDK6)
   05222 Small cell lung cancer
    100385604 (CDK6)
   05223 Non-small cell lung cancer
    100385604 (CDK6)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    100385604 (CDK6)
  09172 Infectious disease: viral
   05160 Hepatitis C
    100385604 (CDK6)
   05164 Influenza A
    100385604 (CDK6)
   05162 Measles
    100385604 (CDK6)
   05163 Human cytomegalovirus infection
    100385604 (CDK6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100385604 (CDK6)
   05169 Epstein-Barr virus infection
    100385604 (CDK6)
   05165 Human papillomavirus infection
    100385604 (CDK6)
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cjc01001]
    100385604 (CDK6)
Enzymes [BR:cjc01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.22  cyclin-dependent kinase
     100385604 (CDK6)
Protein kinases [BR:cjc01001]
Serine/threonine kinases: CMGC group
  CDK family
   100385604 (CDK6)

SSDB

Motif

Pfam:

Pkinase PK_Tyr_Ser-Thr APH Kdo Kinase-like RIO1 FTA2 Seadorna_VP7

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

Ensembl:

UniProt:

LinkDB

Position

AA seq 326 aa
MEKDGLSRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIR
EVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTE
TIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSNGQIKLADFGLARIYSFQMALTSVV
VTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGE
EDWPRDVALPRQAFHAKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYF
QDLERGRENLDSHLPPSQNTSEMNTA

NT seq 981 nt +upstreamnt +downstreamnt
atggagaaggacggcctgagccgcgcggaccagcagtacgaatgcgtagcggagatcggg
gagggcgcctatgggaaggtgttcaaggcccgagacttgaagaacggaggccgtttcgtg
gcgttgaagcgcgtgcgggtgcagaccggcgaggagggcatgccgctctccaccatccgc
gaggtggcggtgctgaggcacctggagaccttcgaacaccccaacgtggtcaggttgttt
gatgtgtgcacagtgtcacgaactgacagagaaaccaaactaactttagtgtttgaacat
gtcgatcaagacttgaccacttacttggataaagttccagagcctggagtgcccactgaa
accataaaggatatgatgtttcagcttctccgaggtctggactttcttcattcacaccga
gtagtgcatcgcgatctaaaaccacaaaacattctggtgaccagcaatggacaaataaaa
ctcgctgacttcggccttgcccgcatctacagtttccagatggctctaacttcagtggtc
gtcacgctgtggtacagagcgcccgaagtcttgctccagtccagctacgccacccccgtg
gatctctggagtgttggctgcatatttgcagaaatgtttcgtagaaagcctctttttcgt
ggaagttcagatgtcgatcaactaggaaaaatcttggacgtaattggactcccaggagaa
gaagactggcctagagatgttgcccttcccaggcaggcttttcatgcaaaatctgcccaa
ccaattgagaagtttgtgacagatattgatgaactaggcaaagacctacttctgaagtgt
ttgacatttaacccagccaaaagaatatctgcctacagcgccctgtctcacccatacttc
caggacctggagaggggcagagaaaacctggattcccacctgcctcccagccagaacacc
tccgagatgaatacagcctga

Callithrix jacchus (white-tufted-ear marmoset): 100408304

Entry

100408304 CDS T03264

Gene name

CDK4

Definition

(RefSeq) cyclin dependent kinase 4

K02089

cyclin-dependent kinase 4 [EC:2.7.11.22]

Organism

cjc Callithrix jacchus (white-tufted-ear marmoset)

Pathway

cjc01522

Endocrine resistance

cjc04110

Cell cycle

cjc04115

p53 signaling pathway

cjc04151

PI3K-Akt signaling pathway

cjc04218

Cellular senescence

cjc04530

Tight junction

cjc04660

T cell receptor signaling pathway

cjc04933

AGE-RAGE signaling pathway in diabetic complications

cjc04934

Cushing syndrome

cjc05160

Hepatitis C

cjc05162

Measles

cjc05163

Human cytomegalovirus infection

cjc05164

Influenza A

cjc05165

Human papillomavirus infection

cjc05166

Human T-cell leukemia virus 1 infection

cjc05167

Kaposi sarcoma-associated herpesvirus infection

cjc05169

Epstein-Barr virus infection

cjc05200

Pathways in cancer

cjc05203

Viral carcinogenesis

cjc05212

Pancreatic cancer

cjc05214

Glioma

cjc05218

Melanoma

cjc05219

Bladder cancer

cjc05220

Chronic myeloid leukemia

cjc05222

Small cell lung cancer

cjc05223

Non-small cell lung cancer

cjc05224

Breast cancer

cjc05225

Hepatocellular carcinoma

Brite

KEGG Orthology (KO) [BR:cjc00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    100408304 (CDK4)
09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    100408304 (CDK4)
   04115 p53 signaling pathway
    100408304 (CDK4)
   04218 Cellular senescence
    100408304 (CDK4)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    100408304 (CDK4)
09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    100408304 (CDK4)
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100408304 (CDK4)
   05203 Viral carcinogenesis
    100408304 (CDK4)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    100408304 (CDK4)
   05225 Hepatocellular carcinoma
    100408304 (CDK4)
   05214 Glioma
    100408304 (CDK4)
   05220 Chronic myeloid leukemia
    100408304 (CDK4)
   05218 Melanoma
    100408304 (CDK4)
   05219 Bladder cancer
    100408304 (CDK4)
   05224 Breast cancer
    100408304 (CDK4)
   05222 Small cell lung cancer
    100408304 (CDK4)
   05223 Non-small cell lung cancer
    100408304 (CDK4)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    100408304 (CDK4)
   04934 Cushing syndrome
    100408304 (CDK4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100408304 (CDK4)
   05160 Hepatitis C
    100408304 (CDK4)
   05164 Influenza A
    100408304 (CDK4)
   05162 Measles
    100408304 (CDK4)
   05163 Human cytomegalovirus infection
    100408304 (CDK4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100408304 (CDK4)
   05169 Epstein-Barr virus infection
    100408304 (CDK4)
   05165 Human papillomavirus infection
    100408304 (CDK4)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    100408304 (CDK4)
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cjc01001]
    100408304 (CDK4)
Enzymes [BR:cjc01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.22  cyclin-dependent kinase
     100408304 (CDK4)
Protein kinases [BR:cjc01001]
Serine/threonine kinases: CMGC group
  CDK family
   100408304 (CDK4)

SSDB

Motif

Pfam:

Pkinase PK_Tyr_Ser-Thr APH Kdo Kinase-like FTA2

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

Ensembl:

UniProt:

LinkDB

Position

AA seq 302 aa
MATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGAGGGLPVSTVREVALLR
RLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLM
RQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWYR
APEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPRD
VSLPRGAFHPRGPRPVQSVVPEMEELGAHLLLEMLTFNPHKRISAFRALQHSYLHKDEGN
PE

NT seq 909 nt +upstreamnt +downstreamnt
atggctacctctcgatatgagccagtggctgaaattggtgtcggtgcctatgggacagtg
tacaaggcccgtgatccccacagtggccactttgtggccctcaagagtgtgagagtcccc
aatggaggagctggaggaggccttcccgtcagcacagttcgtgaagtggccttactgagg
cgactggaggcttttgagcatcccaacgttgtccggctgatggatgtctgtgccacatcg
cgaactgaccgagagatcaaggtaaccctggtgtttgagcatgtagaccaagatctaagg
acatatctggacaaggcacccccaccaggcttgcctgcagagaccatcaaggatctgatg
cgccagtttctaagaggcctagattttcttcatgccaattgcatcgttcaccgagatctg
aagccagagaacattctggtgacaagtggtggaacagtcaagctggctgactttggcctg
gccagaatctacagctaccagatggcacttacacctgtggtggttacactctggtaccga
gctcccgaagttcttctgcagtccacatatgcaacacctgtggacatgtggagtgttggc
tgtatctttgctgagatgtttcgtcgaaagcctctcttctgtggaaactctgaagctgac
cagttgggcaaaatctttgacctgattgggctgcctccagaggatgactggcctcgagat
gtatctctgccccgtggagcctttcaccccagagggccccgcccagtgcagtcggtggta
cctgagatggaggagttgggagcacatctgctgttggaaatgctgacttttaacccacac
aagcgaatctctgcctttcgagctctgcagcactcttacctacataaggatgaaggtaat
ccggagtga

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