Callithrix jacchus (white-tufted-ear marmoset): 100385835 Help Entry 100385835         CDS       T03264                                  Gene name JAK1 Definition (RefSeq) Janus kinase 1   KO K11217   Janus kinase 1 [EC:2.7.10.2] Organism cjc  Callithrix jacchus (white-tufted-ear marmoset) Pathway cjc01521   EGFR tyrosine kinase inhibitor resistance cjc04151   PI3K-Akt signaling pathway cjc04217   Necroptosis cjc04380   Osteoclast differentiation cjc04550   Signaling pathways regulating pluripotency of stem cells cjc04621   NOD-like receptor signaling pathway cjc04630   JAK-STAT signaling pathway cjc04658   Th1 and Th2 cell differentiation cjc04659   Th17 cell differentiation cjc05140   Leishmaniasis cjc05145   Toxoplasmosis cjc05152   Tuberculosis cjc05160   Hepatitis C cjc05161   Hepatitis B cjc05162   Measles cjc05163   Human cytomegalovirus infection cjc05164   Influenza A cjc05165   Human papillomavirus infection cjc05166   Human T-cell leukemia virus 1 infection cjc05167   Kaposi sarcoma-associated herpesvirus infection cjc05168   Herpes simplex virus 1 infection cjc05169   Epstein-Barr virus infection cjc05171   Coronavirus disease - COVID-19 cjc05200   Pathways in cancer cjc05203   Viral carcinogenesis cjc05212   Pancreatic cancer cjc05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:cjc00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     100385835 (JAK1)    04151 PI3K-Akt signaling pathway     100385835 (JAK1)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     100385835 (JAK1)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     100385835 (JAK1)  09150 Organismal Systems   09151 Immune system    04621 NOD-like receptor signaling pathway     100385835 (JAK1)    04658 Th1 and Th2 cell differentiation     100385835 (JAK1)    04659 Th17 cell differentiation     100385835 (JAK1)   09158 Development and regeneration    04380 Osteoclast differentiation     100385835 (JAK1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100385835 (JAK1)    05203 Viral carcinogenesis     100385835 (JAK1)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     100385835 (JAK1)   09162 Cancer: specific types    05212 Pancreatic cancer     100385835 (JAK1)   09171 Infectious disease: bacterial    05152 Tuberculosis     100385835 (JAK1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100385835 (JAK1)    05161 Hepatitis B     100385835 (JAK1)    05160 Hepatitis C     100385835 (JAK1)    05171 Coronavirus disease - COVID-19     100385835 (JAK1)    05164 Influenza A     100385835 (JAK1)    05162 Measles     100385835 (JAK1)    05168 Herpes simplex virus 1 infection     100385835 (JAK1)    05163 Human cytomegalovirus infection     100385835 (JAK1)    05167 Kaposi sarcoma-associated herpesvirus infection     100385835 (JAK1)    05169 Epstein-Barr virus infection     100385835 (JAK1)    05165 Human papillomavirus infection     100385835 (JAK1)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     100385835 (JAK1)    05140 Leishmaniasis     100385835 (JAK1)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     100385835 (JAK1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:cjc01001]     100385835 (JAK1) Enzymes [BR:cjc01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      100385835 (JAK1) Protein kinases [BR:cjc01001]  Non-receptor tyrosine kinases   JAK family [OT]    100385835 (JAK1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase FERM_F2 Jak1_Phl FERM_F1 SH2 Motif Other DBs NCBI-GeneID:  100385835 NCBI-ProteinID:  XP_008999647 Ensembl:  ENSCJAG00000016743 UniProt:  U3BR01 LinkDB All DBs Position 7 AA seq 1153 aa AA seqDB search MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVIFYLSDREPLRLGSGEYTAEEL CIRAAQACRISPLCHNLFALYDENTKLWYAPNHTITVDDKMSLRLHYRMRFYFTNWHGTN DNEQSVWRHSPKKQKNGYEKKKVPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLRISSENEMN WFYSNDSGNVQYYEVMVTGNLGIQWRQKPNVVSVEKEKNKLKRKKLESKHKKDEEKNKVR EEWSSFSYFPEITHIVIKESLVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT CFEKSEVQGAQKQFKNFQIEVHKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFMLK RCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDLVQGEHLGRGTRTHIYSGT LMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDV ENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLL LAREGIDSEFGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFGT TLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAI MRDINKLEEQNPDIVSEKKPTTEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNT GEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPS GSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGD FGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDSD SSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYHLMRKCWEFQPSNRTS FQSLIEGFEALLK NT seq 3462 nt NT seq  +upstreamnt  +downstreamnt atgcagtatctaaatataaaagaggactgcaatgccatggctttctgtgctaaaatgagg agctccaagaagactgaggtgaacctggaggcccctgagccaggggtggaagtgatcttc tatctgtcggacagggagcccctccggctgggcagtggagagtacacagcagaggagctg tgcatcagggctgcacaggcatgccgtatctctcctctttgtcacaatctctttgccttg tatgatgagaacaccaagctctggtatgctccaaatcacaccatcactgtcgatgacaag atgtccctccggctccactacaggatgaggttctatttcaccaattggcatggaaccaat gacaatgagcagtcagtgtggcgtcattctccaaagaagcagaaaaatggctacgagaaa aagaaggttccagatgcaacccctctccttgatgccagttcactggagtatctgtttgct cagggacagtatgatttggtgaaatgcctggctcccattcgagaccccaagaccgagcag gatgggcatgatattgagaacgagtgtctggggatggctgtcctggccatctcgcactat gccatgatgaagaagatgcagttgccagaactgcccaaggacatcagctacaagcgatat attccagaaacattgaacaagtccatcagacagaggaaccttctcacgaggatgcggatt aataatgttttcaaggatttcctcaaggaatttaacaacaagaccatttgtgacagcagc gtgtccacgcatgacctgaaggtgaaatacctggctaccttggaaactttgacaaaacat tacggtgctgaaatatttgagacctccatgttacggatttcatcagaaaatgagatgaat tggttttattcaaatgacagtggaaatgttcagtactatgaagtgatggtgactgggaat cttggaatccagtggaggcagaaaccaaatgttgtttctgttgaaaaggaaaaaaataaa ctgaagcggaagaagctggaaagtaaacacaagaaagatgaggagaaaaacaaggtccgg gaagagtggagcagtttctcttacttccctgaaatcactcacattgtgataaaggagtct ctggtcagcatcaacaagcaggacaacaagaaaatggaactgaagctctcttcccatgag gaggccttgtcctttgtgtccctggtagacggctacttccggctcacagcagacgcccat cattacctctgcactgatgtggcccccccgttgattgtccacaacatacaaaatggctgt cacggtccaatctgtacagaatacgccatcaataaattgcggcaagaaggaagtgaggag gggatgtatgtgctgagatggagctgcacggactttgacaacatcctcatgaccgtcacc tgctttgagaagtctgaggtgcagggtgcccagaagcagttcaagaactttcagatcgag gtgcacaagggccgctacagcctgcacggttcggaccgcagcttccccagcttgggcgac ctcatgagccacctcaagaaacagatcctgcgcacggataatatcagcttcatgctgaaa cgctgctgccagcccaagccccgagaaatctccaacctgctggtggctactaagaaagcc caggagtggcagcccgtctaccccatgagccagctgagttttgatcggatcctcaagaag gatctggtgcagggcgagcaccttgggagaggcacgagaacacacatctactctgggacc ctgatggattacaaggatgacgaaggaacttctgaagagaagaagataaaagtgatcctc aaagttttagaccccagccacagggatatttccctggccttcttcgaagcagccagcatg atgagacaggtctctcacaaacacatcgtgtacctctatggcgtctgtgtccgagacgtg gagaatatcatggtggaagagtttgtggaaggggggcctctggatctcttcatgcaccgg aaaagcgatgtccttaccacaccatggaaattcaaagtggccaaacagctggccagtgcc ctcagttacttggaggataaagacttggttcatggaaatgtgtgcactaaaaacctcctc ctggcccgtgagggcattgacagcgagtttggcccattcatcaagctcagtgaccctggc atccccatcacggtgctgtctagacaagagtgcattgaacgaatcccatggattgctcct gagtgtgtggaggactccaagaatctgagtgtggctgctgacaagtggagctttggaacc acgctctgggaaatctgctacaatggcgagatccccttgaaagacaagacactgattgag aaagagagattctatgaaagccggtgcaggccggtgacaccgtcatgtaaggagctggct gacctcatgacccgctgcatgaactacgaccccaatcagaggcccttctttcgagccatc atgagagacattaataagcttgaagagcagaatccagatattgtttcagaaaaaaaacca acaaccgaagtggaccccacacattttgaaaagcgcttcctaaagaggatccgtgacttg ggagagggccactttgggaaggttgagctctgcaggtatgaccccgaaggggacaataca ggggagcaggtggctgtcaaatctctgaagcctgagagtggaggtaaccacatagctgat ctgaaaaaggaaatcgaaatcttaaggaacctctatcatgagaacattgtgaagtacaaa ggaatctgcacggaagacggtggaaatggtattaagctcatcatggaatttctgccttcg ggaagccttaaggaatatcttccaaagaataagaacaaaattaacctcaaacagcagcta aaatatgctgttcagatttgtaaggggatggactatttgggttctcggcaatatgttcac cgggacttagcagcgagaaatgtccttgttgagagtgaacaccaagtgaaaattggagac tttggtttaaccaaagcaattgaaaccgataaggagtattacacagtcaaggacgaccgg gacagccctgtgttttggtatgctccagaatgtttaatgcaatctaaattttatattgcc tctgacgtctggtcttttggagttactctgcatgagctgctgacttactgtgattcagat tccagtcccatggccttgttcctgaaaatgataggcccaacccatggccagatgacagtc acaagacttgtgaatacattaaaagaaggaaaacgcttgccgtgtccacctaactgtcca gatgaggtttatcatcttatgaggaaatgctgggaattccaaccatccaatcggacaagc tttcagagccttattgaaggatttgaagcacttttaaaataa

Callithrix jacchus (white-tufted-ear marmoset): 100397491 Help Entry 100397491         CDS       T03264                                  Gene name JAK3 Definition (RefSeq) Janus kinase 3   KO K11218   Janus kinase 3 [EC:2.7.10.2] Organism cjc  Callithrix jacchus (white-tufted-ear marmoset) Pathway cjc04062   Chemokine signaling pathway cjc04151   PI3K-Akt signaling pathway cjc04217   Necroptosis cjc04550   Signaling pathways regulating pluripotency of stem cells cjc04630   JAK-STAT signaling pathway cjc04658   Th1 and Th2 cell differentiation cjc04659   Th17 cell differentiation cjc05161   Hepatitis B cjc05162   Measles cjc05166   Human T-cell leukemia virus 1 infection cjc05169   Epstein-Barr virus infection cjc05200   Pathways in cancer cjc05203   Viral carcinogenesis cjc05223   Non-small cell lung cancer cjc05340   Primary immunodeficiency Brite KEGG Orthology (KO) [BR:cjc00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     100397491 (JAK3)    04151 PI3K-Akt signaling pathway     100397491 (JAK3)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     100397491 (JAK3)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     100397491 (JAK3)  09150 Organismal Systems   09151 Immune system    04658 Th1 and Th2 cell differentiation     100397491 (JAK3)    04659 Th17 cell differentiation     100397491 (JAK3)    04062 Chemokine signaling pathway     100397491 (JAK3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100397491 (JAK3)    05203 Viral carcinogenesis     100397491 (JAK3)   09162 Cancer: specific types    05223 Non-small cell lung cancer     100397491 (JAK3)   09163 Immune disease    05340 Primary immunodeficiency     100397491 (JAK3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100397491 (JAK3)    05161 Hepatitis B     100397491 (JAK3)    05162 Measles     100397491 (JAK3)    05169 Epstein-Barr virus infection     100397491 (JAK3)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:cjc01001]     100397491 (JAK3) Enzymes [BR:cjc01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      100397491 (JAK3) Protein kinases [BR:cjc01001]  Non-receptor tyrosine kinases   JAK family [OT]    100397491 (JAK3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase FERM_F1 FERM_F2 Jak1_Phl Kdo APH pKID Motif Other DBs NCBI-GeneID:  100397491 NCBI-ProteinID:  XP_017822788 LinkDB All DBs Position 22 AA seq 1026 aa AA seqDB search MTVAQETKGPTQEGAEWDFPLAASWLCPPFERPGSLPARQAALMAPPNEETPLIPQRSCS LLSTEAGALQVLLPARGPGPPQRLSFSYGDHLAEDLCVQAAKASGILPVYHSLFALATED LSCWFPPSHIFSVEDATTHVLCYRIRFYFPNWCGLEKCHRFGLRKDLASAVLDLPVLEHL FAQHRSDLVSGRLAVGLSLKEQGECLSLAVLDLARMSREQAQRPGELLKTVREAEFPGLP EALSXVALVDGYFRLITDSQHFFCKEVAPPRLLEEVAEQCHGPITLDFAINKLKTGGSLP GSYVLRRSPQDFESFLLTVCVQTPLGPDYKGCLIRRSPTGSFFLVGLSQPYSSVRELLAT CWDGGLHVDGVPVTLTSCCIPRPKEKSNLIVVRRGHSPPTSSLVQPQSQCQLSQMTFHKI PADSLEWHENLGHGSFTKIYRGCRHEAVDGEARKTEVLLKVMDAKHRNCMESFLEAASLM SQVSYRHLVLLHGVCMAGDSTMVQEFVHLGAIDMYLRKRGHLVPASWKLQVVKQLAYALN YLEDKGLPHGNVSARKVLLARDGGDGSPPFIKLSDPGVSPTVLSLEMLTDRIPWVAPECL QGAQTLSLEADKWGFGATVWEVFSGVTMPISALDPAKKLQFYEDRQQLPAPKWTELALLI QQCMDYEPVRRPSFRAIIRDLNSLISADYELLSDLTPGALAPRDGLWNGTQLYACQDPTI FEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQLQHSGPDQQRDFQREIQILK ALHSDFIVKYRGVSYGPGRQSLRLVMEYLPSGCLRDFLQRHRAHLDASRLLLYASQICKG MEYLGSRRCVHRDLAARNILVESEAHVKIADFGLAXLLPLDKXXXXVPLPQGKPPESLSD NIFSRQSDVXSFGVVLYELFRYCDKRCSPSAEFLRLMACERDVPALCRLLELLEEGQRLP APPACPAEVHELMKLCWATSPQDRPSFSALGPQLDMLCVSRSRRCETPTFPAHPFSVLQT SGLGLC NT seq 3081 nt NT seq  +upstreamnt  +downstreamnt atgacagtggctcaggaaaccaaggggcccacacaggaaggagccgagtgggactttcct ctcgctgcctcctggctctgccctccctttgaacgcccaggatccctgcctgctaggcaa gctgccctcatggcacctccaaacgaagagacgcccctgatccctcagcgttcctgcagc ctcttgtccacggaagctggtgccctacaagtgctgctgcctgcccggggcccagggccc ccccagcgcctatctttctcctatggggaccacttggctgaggacctgtgtgtgcaggct gccaaggccagcggcatcctgcctgtgtaccactccctctttgctctggccaccgaggac ctgtcctgctggtttcccccaagtcacatcttctccgtggaagatgccaccacccatgtc ctctgctacaggattcgcttttacttccccaattggtgtgggctggagaagtgccaccgc tttgggctgcgaaaggatttggccagcgctgtccttgacctgccagtcctggagcacctc tttgcccagcaccgcagtgacctggtgagtggacgcctcgctgtgggcctcagcctcaag gagcagggtgagtgtctcagcttggctgtgctggacctggcccggatgtcaagagagcag gcccagcggccaggagaactgttgaagactgtcagggaggccgagttcccggggctgccc gaggcgctgtccnttgtggcgctcgtggacggctacttccggctgatcacggactcccag cacttcttctgcaaggaggtggcaccgccgaggctgctggaggaggtggccgagcagtgc cacggccccatcactctggactttgccatcaacaagcttaagactgggggctcacttcct ggctcctatgttctccgccgcagcccccaggactttgagagcttcctccttactgtttgt gttcagacccccctcggtcctgattacaagggctgcctcatccggcgcagccccacagga tccttttttctggttggcctcagccaaccctacagcagtgttcgagagctcctggcaacc tgctgggatggagggctgcacgtagatggggtcccagtgaccctcacctcctgctgtatc cccagacccaaagaaaagtccaacctgattgtggtccggagaggtcacagcccacccacg tcctccctggttcagccccaatcccaatgccagctgagtcagatgacatttcacaagatc cctgcggacagcctggagtggcatgagaacctgggccacgggtccttcaccaagatttac cggggctgtcgccacgaggcagtggatggggaggcccgaaagacagaggtgctgctgaag gtgatggacgccaaacacaggaactgcatggagtcattcctggaagcagcgagcttgatg agtcaagtgtcataccggcatctcgtgttactgcacggcgtgtgcatggctggagacagc accatggtgcaggaatttgtacacctgggggcaatagacatgtatctgcgcaagcgtggc cacctggtgccagccagctggaagctacaggtggtcaaacagctggcctatgccctcaac tatctggaggacaaaggcctcccccacggcaatgtctctgcccgaaaggtgctcctggct cgggacgggggtgatgggagcccgcccttcatcaagctgagtgaccctggggtcagcccc acggtgctaagcctggagatgctcacggacaggattccctgggtggcccccgagtgcctc caaggggcccagacacttagcctggaagctgacaagtggggcttcggcgccaccgtctgg gaggtgtttagtggcgtcaccatgcccatcagtgccctggatcccgctaagaaactccag ttttatgaggaccggcagcagctgccggcccccaagtggacagagctggctctgctcatt cagcagtgcatggactacgagccagtccggagaccctcctttcgagccatcatccgtgac ctcaacagcctcatctctgcagattatgagctcctctcagacctcacacctggtgccctg gcacctcgtgatgggctgtggaatggtacccagctctatgcctgccaagaccccacgatc tttgaggagagacaccttaagtacatctcacagctgggcaagggcaactttggcagcgtg gagctgtgccgctatgacccgctaggcgacaacacaggtgccctggtggccgtgaaacag ctgcagcacagcgggccagaccagcagagggacttccagcgggagatccagatcctcaaa gcactgcacagtgacttcattgtcaagtatcgtggtgtcagctacggcccgggccgccag agcctgcggctggtcatggagtacctgcccagcggctgcctgcgcgacttcctgcagcgg catcgcgcgcatctcgatgccagccggcttctcctctacgcctcgcagatctgcaagggc atggagtacctgggctcccgccgctgcgtgcaccgcgacctggcagcccggaacatcctg gtggagagcgaggcacacgtcaagatcgctgacttcggtctagcctagctgcttccgctt gacaaannnnnnnnnnctgtccccctcccccaaggtaagccccccgagtccctctcggac aacatattctctcgccaatcagacgtctgaagcttcggggttgtcctgtacgagctcttc agatactgcgacaaaagatgcagcccctcggcggagttcctgcggttgatggcctgtgag cgggatgtccccgccctctgccgcctcctggaactgctggaggagggccagaggctgcca gcacctcctgcctgccctgctgaggttcacgagctcatgaagctgtgctgggccactagc ccacaggaccggccgtcattcagcgccctgggcccccagctggacatgctgtgtgtaagt cgaagccggaggtgtgagactcccaccttccctgctcacccattctctgtcctgcagacc tctggattaggtctctgttga

Callithrix jacchus (white-tufted-ear marmoset): 100405583 Help Entry 100405583         CDS       T03264                                  Gene name TYK2 Definition (RefSeq) tyrosine kinase 2   KO K11219   non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2] Organism cjc  Callithrix jacchus (white-tufted-ear marmoset) Pathway cjc04217   Necroptosis cjc04380   Osteoclast differentiation cjc04621   NOD-like receptor signaling pathway cjc04630   JAK-STAT signaling pathway cjc04658   Th1 and Th2 cell differentiation cjc04659   Th17 cell differentiation cjc05145   Toxoplasmosis cjc05160   Hepatitis C cjc05161   Hepatitis B cjc05162   Measles cjc05164   Influenza A cjc05165   Human papillomavirus infection cjc05167   Kaposi sarcoma-associated herpesvirus infection cjc05168   Herpes simplex virus 1 infection cjc05169   Epstein-Barr virus infection cjc05171   Coronavirus disease - COVID-19 Brite KEGG Orthology (KO) [BR:cjc00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     100405583 (TYK2)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     100405583 (TYK2)  09150 Organismal Systems   09151 Immune system    04621 NOD-like receptor signaling pathway     100405583 (TYK2)    04658 Th1 and Th2 cell differentiation     100405583 (TYK2)    04659 Th17 cell differentiation     100405583 (TYK2)   09158 Development and regeneration    04380 Osteoclast differentiation     100405583 (TYK2)  09160 Human Diseases   09172 Infectious disease: viral    05161 Hepatitis B     100405583 (TYK2)    05160 Hepatitis C     100405583 (TYK2)    05171 Coronavirus disease - COVID-19     100405583 (TYK2)    05164 Influenza A     100405583 (TYK2)    05162 Measles     100405583 (TYK2)    05168 Herpes simplex virus 1 infection     100405583 (TYK2)    05167 Kaposi sarcoma-associated herpesvirus infection     100405583 (TYK2)    05169 Epstein-Barr virus infection     100405583 (TYK2)    05165 Human papillomavirus infection     100405583 (TYK2)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     100405583 (TYK2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:cjc01001]     100405583 (TYK2) Enzymes [BR:cjc01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      100405583 (TYK2) Protein kinases [BR:cjc01001]  Non-receptor tyrosine kinases   JAK family [OT]    100405583 (TYK2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase Jak1_Phl FERM_F2 FERM_F1 Kdo Kinase-like APH Motif Other DBs NCBI-GeneID:  100405583 NCBI-ProteinID:  XP_008985492 Ensembl:  ENSCJAG00000006781 UniProt:  U3F2R3 LinkDB All DBs Position 22 AA seq 1187 aa AA seqDB search MPLRHRGTAKGGKPVGDGAQPVATMGGLKVLLHWAGPGGGDPWVIFSKSSLTAEEVCIHI AHKLGITPPCFNLFALFDAQAQVWLPPNHILEIPRDAGLMLYFRMRFYFRNWHGMNPQEP AVYRCGPPGAEASSDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSSEEEIHHFK NESLGMAFLHLCHLALHHGVPLEEVAKKTSFKDCIPHSFRRQIRQHNALTRLRLRNVFRR FLRDFQPGCLSQQMVMVKYLATLERLAPRFGTEHMPVCHLRLLDQAEGEPCYIRDSGEAP TDPGPESAAGPPTHEVLVTGTGGIQWWPVQEEVSKEEGSIRGSGSNLQASLSGKKAKAHK AIAQPADKPREPPRVYFCDFRDITHVVLKERRVSIHRQDNKCLELSLPSRAMALSFVSLV DGYFRLTADSSHYLCHEVAPPRLVMSIQDGIHGPLLEPFVQAKLRTEDGLYLIHWSTSHP YRLILTVAQRSQAPDGTQSLQLRKFPIEQQAGAFILEGWGRSFSSVRELGAALRGCSLKV GDDCFSLRRCCLPQPGETSNLIIMRGALASTRPLNLSQLSFHRVNQKEITQLSHLGQGTR TNVYEGRLRVEGSGGPEEGKMDDEFPPGPSRDCGQELRVVLKVLDPSHHDIALAFYETAS LMSQVSHVHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGCVPMAWKMVVAQQLAS ALSYLENKNLVHGNVCGRNILLARLGLEEGTSPFIKLSDPGVGLGALSREERVERIPWMA PECLPGGPNSLGTATDKWGFGATLLEICSDGEAPLQSRSPSEKERFYQRQHRLPQPSCPE LATLTGQCLTYEPTQRPSFRTILRDLTRLQPYNLADVLTVNLDSPASDPTVFHKRYLKKI RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIV KYKGCSEDQGEKSVQLVMEYVPLGSLRDYLPRHSVGLAQLLLFAQQICEGMAYLHAQHYI HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY ASDVWSFGVTLYELLTHCASSQSPPTKFLELIGITQGQVTVLRLTELLERGERLPRPDKC PCEVYHLMKNCWEMEASFRPTFQNLIPILKTVHEKYQGQAPSVFSVC NT seq 3564 nt NT seq  +upstreamnt  +downstreamnt atgcctctgcgccatcggggaacagccaagggcggcaagcctgttggggatggagcccag cccgtggctaccatgggaggcctgaaggtgcttctgcactgggctggtccaggcggcggg gacccctgggtcatcttcagcaagtcatcgctgacagctgaggaagtctgcattcacatc gcgcataaactcggtatcactcctccctgtttcaatctcttcgccctctttgatgcccag gcccaagtctggttgcccccaaaccacatcctagagatccccagagacgcaggcctgatg ctgtatttccgcatgaggttttatttccggaattggcatggcatgaatcctcaggagcca gctgtgtaccgctgtgggcccccaggagctgaggcatcctcagatcagacagcacaaggg atgcaactcctggacccagcctcatttgaatacctctttgagcagggcaagcatgagttt gtgaatgatgtggcatcactgtgggagctgtcgagcgaggaggagatccaccactttaag aatgagagcctgggcatggcctttctgcacctctgtcacctcgccctccaccatggcgtc cccctggaggaggtggccaagaagaccagcttcaaggactgcatcccgcactccttccgt cggcagatccggcagcacaacgccctgacccggctacgccttcggaacgtcttccgcagg ttcctgcgggacttccagccaggctgcctctcccagcaaatggtcatggtcaaatacctg gccacactcgagcggctggcaccccgctttggcacagagcatatgcccgtgtgccacctg aggctgctggaccaggctgagggggagccctgctacatacgggacagtggggaggcccct acagaccctggccctgagtctgctgctgggccccccacccacgaggtgctggtgacaggc actggtggcatccagtggtggccagtacaggaggaggtgagcaaggaggagggttctatc aggggcagcggcagcaatctccaagccagcctgtctgggaagaaagccaaggctcacaag gcaatcgcccagccggcggacaagccgagggagccgcctcgggtctacttctgtgacttc cgggacatcacccatgtggtgctgaaagagcgccgtgtcagcatccaccggcaggacaac aagtgcctggagctgagcctgccttctcgggctatggcgctgtccttcgtgtcactggtg gacggctatttccgcctgacagccgactccagccactacctgtgccacgaggtggctccc ccacggctggtgatgagcatccaggacgggatccatggacccctgctggagccatttgtg caggccaagctgcggaccgaggatggcctgtacctcattcactggagcaccagccacccc tatcgcctgatcctcacggtggcccagcgtagccaggcaccagatggcacgcagagcttg cagctccggaagttccccattgagcagcaggctggggccttcatactggagggctggggc cggtccttctccagtgttcgggaacttggggctgctttgcggggctgctcactgaaagta ggggatgactgcttctctctgcgtcgctgttgcctgccccaaccaggagaaacctccaac ctcatcatcatgcggggggctctggccagcaccaggccactcaacctcagccagctcagc ttccaccgggtcaaccagaaggagatcacccagctgtcccacttgggtcagggtacaagg accaatgtgtatgagggccgcctacgagtggagggcagtgggggccctgaggagggcaag atggacgacgagttcccccccgggcccagcagggactgtgggcaggagctgcgagtggtc cttaaagtgctggatcctagtcaccatgacattgccctggccttctatgagacagccagc ctcatgagccaggtctcccatgtgcacctggccttcgtgcatggcgtctgtgtgcgcggc cctgaaaatatcatggtgacagagtacgtggagcacgggcccctggacgtgtggctgcgg agggagcggggctgtgtgcccatggcttggaagatggtggtggcccagcagctggccagc gccctcagctacctggagaacaagaacctggttcacggtaatgtgtgtggccggaacatc ctgctggcacgtctggggctggaggagggcaccagccccttcatcaagctgagtgatccc ggcgtgggcctgggcgccctctccagggaggagcgcgtggaacggatcccctggatggcc cctgagtgcttgccaggcgggcccaatagcctaggcactgccacggacaagtggggcttt ggtgccaccctcctcgagatctgctctgatggagaggccccccttcagagtcgcagcccc tccgagaaagagcgtttctaccagaggcagcaccggctgccccagccctcctgcccagag ctggccacactcactggccagtgtctgacctatgagccaacccagaggccatcattccgc actatcctgcgtgacctcacccggctgcaaccctacaatcttgctgatgtcttgactgtg aacctggactcacctgcgtcagaccctactgttttccacaagcgctatttgaaaaagatc cgagatctgggcgagggccacttcggtaaggtcagcttgtattgctacgatccgaccaac gacggcactggcgagatggtggcggtgaaagccctcaaggcagactgcggcccccagcac cgctcaggctggaagcaggagattgatattctgcgcacgctctaccacgagcacatcgtc aagtacaagggctgcagcgaggaccaaggcgagaagtcggtgcaactggtcatggagtac gtgccactgggcagcctccgagactacctgccccggcacagcgtcgggctggcccagctg ctgctcttcgcccagcagatctgcgagggcatggcctatctgcacgcgcagcactacatc caccgagacctagccgcgcgcaacgtgctgctggacaacgacaggctggtcaagatcggg gactttggcctagccaaggccgtgcccgaaggccacgagtactaccgtgtgcgcgaggat ggggacagccccgtgttctggtatgccccagaatgcctgaaggagtataaattctactat gcgtccgatgtctggtccttcggggtgaccctgtatgagctgctgacgcactgtgcctcc agccagagcccccccacgaaattccttgagctcataggcatcacccagggtcaggtgaca gtactgagactcactgagttgctggaacgaggggagaggctgccacggcccgacaaatgt ccctgtgaggtctatcacctcatgaagaactgctgggagatggaggcatccttccgccca accttccagaacctcatacccatcctgaagacagtccatgagaagtaccaaggccaggcc ccttcggtgttcagtgtgtgctaa

Callithrix jacchus (white-tufted-ear marmoset): 100413251 Help Entry 100413251         CDS       T03264                                  Gene name JAK2 Definition (RefSeq) Janus kinase 2   KO K04447   Janus kinase 2 [EC:2.7.10.2] Organism cjc  Callithrix jacchus (white-tufted-ear marmoset) Pathway cjc01521   EGFR tyrosine kinase inhibitor resistance cjc04062   Chemokine signaling pathway cjc04151   PI3K-Akt signaling pathway cjc04217   Necroptosis cjc04550   Signaling pathways regulating pluripotency of stem cells cjc04630   JAK-STAT signaling pathway cjc04658   Th1 and Th2 cell differentiation cjc04659   Th17 cell differentiation cjc04725   Cholinergic synapse cjc04917   Prolactin signaling pathway cjc04920   Adipocytokine signaling pathway cjc04933   AGE-RAGE signaling pathway in diabetic complications cjc04935   Growth hormone synthesis, secretion and action cjc05140   Leishmaniasis cjc05145   Toxoplasmosis cjc05152   Tuberculosis cjc05161   Hepatitis B cjc05164   Influenza A cjc05167   Kaposi sarcoma-associated herpesvirus infection cjc05168   Herpes simplex virus 1 infection cjc05200   Pathways in cancer cjc05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:cjc00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     100413251 (JAK2)    04151 PI3K-Akt signaling pathway     100413251 (JAK2)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     100413251 (JAK2)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     100413251 (JAK2)  09150 Organismal Systems   09151 Immune system    04658 Th1 and Th2 cell differentiation     100413251 (JAK2)    04659 Th17 cell differentiation     100413251 (JAK2)    04062 Chemokine signaling pathway     100413251 (JAK2)   09152 Endocrine system    04920 Adipocytokine signaling pathway     100413251 (JAK2)    04917 Prolactin signaling pathway     100413251 (JAK2)    04935 Growth hormone synthesis, secretion and action     100413251 (JAK2)   09156 Nervous system    04725 Cholinergic synapse     100413251 (JAK2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100413251 (JAK2)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     100413251 (JAK2)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     100413251 (JAK2)   09171 Infectious disease: bacterial    05152 Tuberculosis     100413251 (JAK2)   09172 Infectious disease: viral    05161 Hepatitis B     100413251 (JAK2)    05164 Influenza A     100413251 (JAK2)    05168 Herpes simplex virus 1 infection     100413251 (JAK2)    05167 Kaposi sarcoma-associated herpesvirus infection     100413251 (JAK2)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     100413251 (JAK2)    05140 Leishmaniasis     100413251 (JAK2)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     100413251 (JAK2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:cjc01001]     100413251 (JAK2) Enzymes [BR:cjc01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      100413251 (JAK2) Protein kinases [BR:cjc01001]  Non-receptor tyrosine kinases   JAK family [OT]    100413251 (JAK2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase FERM_F2 FERM_F1 Jak1_Phl SH2 RIO1 Kinase-like Motif Other DBs NCBI-GeneID:  100413251 NCBI-ProteinID:  XP_002742952 Ensembl:  ENSCJAG00000011228 LinkDB All DBs Position 1 AA seq 1130 aa AA seqDB search MACLTVTEMEGTSTSSINQNGDISGNVNSMKQIDPVLQVYLYHSLGKAEADYLTFPSGEY VAEEICIAASKACGITPLYHNMFALMSETERIWYPPNHVFHVDESTRDNVLYRIRFYFPH WYCSGNNRTYRHGISRGAEAPLLDDCVMSYLFSQWRHDFVHGWIKVPVTHETQEECLGMA VLDMMRIAKEKDQTPLAIYNSISYKTFLPKCIRAKIQDYHILTRKRIRYRFRRFIQQFSQ CKATARNLKLKYLINLETLQSAFYTEKFEVKEPGSGPSGEEIFATIIITGNGGIQWSRGK HKESETLTAQDLQLYCDFPNIIDVSIKQANQEGSNESRVVTIHKQDGKNLEIELSSLREA LSFVSLIDGYYRLTADAHHYLCKEVAPPTVLENIQSNCHGPISMDFAISKLKKAGNQTGL YVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENEEYNLSGTKKNFSSLKDLLNCYQ METVRSDNIIFQFTKCCPPKPKDKSNLLVFRMNGVSDVPISPTLQRHNNVNQMVFHKIRN EDLIFNESLGQGTFTKIFKGIRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMS QLSHKHLVLNYGICVCGEENILVQEFVKFGSLDTYLKKNKNCINILWKLEVAKQLAWAMH FLEEKTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPE CIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWAELAN LINNCMDYEPDFRPSFRAVIRDLNSLFTPDYELLTENDMLPNTRTGLSGFSVAFEDRDPT QFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEIL KSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQICK GMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYA PESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELL KNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNMAE NT seq 3393 nt NT seq  +upstreamnt  +downstreamnt atggcttgccttacagtgacagaaatggagggaacatccacgtcttctataaatcagaat ggtgatatttctggaaatgtcaattctatgaagcaaatagatccggttcttcaggtgtat ctttaccattcccttgggaaagctgaggcagattatctcacatttccatctggggaatat gttgcagaagaaatctgtattgctgcttctaaagcttgtggcatcacacctttgtatcat aatatgtttgctttaatgagtgaaacagaaaggatctggtatccacccaaccatgtcttc catgtagatgaatcaaccagggataatgtactctacagaataagattttactttcctcat tggtattgcagcggcaacaacagaacctatcggcatggaatatctcgaggtgctgaagct cctcttctcgatgactgtgtcatgtcttaccttttttctcagtggcggcatgattttgtg catggatggataaaagtacctgtgactcatgaaactcaggaagaatgtcttgggatggca gtgttagatatgatgagaatagctaaagaaaaggatcagactccactggccatctataat tctatcagctacaagacattcttaccaaaatgtattcgagcaaagatccaagactatcac attttgacaaggaagcgaataaggtacagatttcgcagatttattcagcagttcagccaa tgcaaagccactgccagaaacttgaaacttaagtatcttataaatctggaaactctgcag tctgccttctacacagagaaatttgaagtaaaagaacctggaagtggtccttcaggtgag gagatttttgcaaccattataataactggaaacggtggaattcagtggtcaagagggaaa cataaagaaagtgagacactgacagcacaggatttacagttgtattgtgattttcctaat attattgatgtcagtattaagcaagcaaaccaagagggttcaaatgaaagcagagttgtg actatccataagcaagatggtaaaaatctggaaattgaacttagctcattaagggaagct ttgtcttttgtgtcattaattgatggatattatagattaacggcagatgcacatcattac ctctgtaaagaagtagcacctccaacggtgcttgaaaatatacaaagcaactgtcatggc ccaatttcaatggactttgccatcagtaaactgaagaaagcaggcaatcagactggactg tatgtacttcgatgcagtcctaaggacttcaataaatattttctgacttttgctgtcgag cgagaaaatgtcattgaatataaacactgtttgattacaaaaaatgagaatgaagagtac aacctcagtgggacaaagaagaacttcagtagtcttaaagatcttttgaattgttaccag atggaaactgttcgctcagacaatataattttccagtttactaaatgctgtcccccaaag ccaaaagataaatcaaaccttctagtcttcagaatgaatggtgtttctgatgtcccaatc tcaccaacattacagaggcataataacgtgaaccaaatggtgtttcacaaaattagaaat gaagatttgatatttaatgaaagccttggccaaggcacttttacaaagatttttaaaggc atacgaagagaagtaggagattatggccaactgcatgaaacagaagttcttttaaaagtt ctggataaagcacatagaaactattcagagtctttctttgaagcagcaagcatgatgagc cagctttctcacaagcatttggttttaaattatggaatatgtgtctgcggagaggagaat attctggttcaggagtttgtaaaatttggatcactagatacatacctgaaaaagaataaa aattgtataaatatattatggaaacttgaagttgctaaacagttggcatgggccatgcat tttctagaagaaaagacccttattcatgggaatgtgtgcgccaaaaatattctacttatc agagaagaagacaggaagacaggaaatcctcctttcatcaaactcagtgaccctggcatt agtattacagttttgccaaaggacattcttcaggagagaataccatgggtaccacctgaa tgcattgaaaatcctaaaaatttaaatttggcaacagacaaatggagttttggtaccact ttgtgggaaatctgcagtggaggagataaacccttaagtgctctggattctcaaagaaag ctgcaattttatgaagataggcaccagcttcctgcaccaaagtgggcagaattagcaaac cttataaataattgtatggattatgaaccagatttcaggccttccttcagagccgtcata cgagatcttaacagtttgtttacaccagattatgaactattaacagaaaatgacatgtta ccaaatacgaggacaggtctttcagggttttctgttgcttttgaagacagggatcctaca cagtttgaagagagacatttgaaatttctacagcaacttggcaagggtaattttgggagt gtggagatgtgccgatatgaccctctacaggacaacactggggaggtggtggctgtaaaa aagcttcagcatagtactgaagagcacctgagagactttgaaagggaaattgaaatcttg aaatcactgcagcatgacaacattgtaaagtacaagggagtgtgctacagtgctggtcgg cgaaatctaaaattaattatggaatatttaccatatggaagtttacgagactatcttcaa aaacataaagaacggatagatcacaaaaaacttctgcagtacacatctcagatctgcaag ggtatggagtatcttggtacaaaaaggtatatccacagggatctggcgacaagaaatata ttggtagagaatgagaacagagttaaaattggagattttgggttaaccaaagtcttgcca caagacaaagaatactataaagtaaaagaacctggtgaaagccccatattctggtatgct ccagaatcactgacagagagcaagttttctgtggcctcagatgtttggagctttggagta gttctgtatgaacttttcacatacattgagaagagtaaaagtccaccagcggaatttatg cgtatgattggcaatgacaaacaaggacagatgatcgtgttccatttgatagaactgttg aagaataatggaagattaccaagaccagatggatgcccagatgagatttatatgatcatg acagaatgctggaacaataatgtaaatcaacgcccctcctttagggatctagctcttcga gtggatcaaataagggataacatggctgaataa

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