Callithrix jacchus (white-tufted-ear marmoset): 100400572
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Entry
100400572 CDS
T03264
Symbol
CYP17A1
Name
(RefSeq) steroid 17-alpha-hydroxylase/17,20 lyase precursor
KO
K00512
steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase [EC:
1.14.14.19
1.14.14.32
]
Organism
cjc
Callithrix jacchus (white-tufted-ear marmoset)
Pathway
cjc00140
Steroid hormone biosynthesis
cjc01100
Metabolic pathways
cjc04913
Ovarian steroidogenesis
cjc04917
Prolactin signaling pathway
cjc04927
Cortisol synthesis and secretion
cjc04934
Cushing syndrome
Module
cjc_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
cjc_M00110
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
cjc_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
cjc_M00977
C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
cjc00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
100400572 (CYP17A1)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
100400572 (CYP17A1)
04917 Prolactin signaling pathway
100400572 (CYP17A1)
04927 Cortisol synthesis and secretion
100400572 (CYP17A1)
09160 Human Diseases
09167 Endocrine and metabolic disease
04934 Cushing syndrome
100400572 (CYP17A1)
09180 Brite Hierarchies
09181 Protein families: metabolism
00199 Cytochrome P450 [BR:
cjc00199
]
100400572 (CYP17A1)
Enzymes [BR:
cjc01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
1.14.14.19 steroid 17alpha-monooxygenase
100400572 (CYP17A1)
1.14.14.32 17alpha-hydroxyprogesterone deacetylase
100400572 (CYP17A1)
Cytochrome P450 [BR:
cjc00199
]
Cytochrome P450, animal type
CYP17 family
100400572 (CYP17A1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
p450
Motif
Other DBs
NCBI-GeneID:
100400572
NCBI-ProteinID:
NP_001254697
Ensembl:
ENSCJAG00000018089
UniProt:
Q5IFI0
LinkDB
All DBs
Position
12:complement(92479196..92487678)
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AA seq
507 aa
AA seq
DB search
MWELVALLLFTLTYFFWPKRRSPGAKYPKSLLSLPLVGSLPFLPRHGHMHQNLFKLQKKY
GPIYSLRMGRNKTVIVGNHQLAKEVLMKKGKDFSGRPQVATIDILSNKGKGIAFADYGAH
WQLHRRLVMAAFSLFKEGDQKLEKIICQEISILCDVLATHDGQSIDISFPVFMAVTNVIS
LICFNSSYKDGAPELKIVETYNEGIVEALGKENLVDMFPWLKIFPNKSLEKLKTYVKLRN
DLLNKIIGNYKEKFHSDSITSMLDVLMQAKKNADNGNASPDQDAELLSDNHILTTVGDIF
GAGVETTTSVVKWIVAYLLHNPQVKKKLYDEIDQNVGFSRTPTVSDRNCLLLLEATIREV
LRIRPVAPMLIPHKANVDTSIGEFAVDKGTHVIINLWALHHSEEWHQPDKFMPERFLNQA
GTQLISPTLSYLPFGAGPRSCIGEILARQELFLIMAWMLQRFDLEVPDDGELPSLEGNPK
VVFMIDSFKVKIKVRQAWREAQAEGST
NT seq
1524 nt
NT seq
+upstream
nt +downstream
nt
atgtgggagcttgtggctctcttgctgtttaccctcacctatttcttttggcccaagaga
aggtcccctggtgccaagtaccccaagagcctcctgtccctgcccctggtgggcagcctg
ccattcctccccagacatggccatatgcatcagaacttattcaagctgcagaaaaaatat
ggacctatctattcccttcgtatgggcaggaacaaaacagtgattgtcggcaaccatcag
ctggccaaggaggtacttatgaagaagggcaaggacttctctggtcggcctcaagtggca
accatagacatcctgtccaacaagggcaagggcatcgccttcgctgactacggtgcacac
tggcagctgcatcgaaggcttgtgatggccgccttttccctgttcaaggagggtgatcag
aagctggagaagatcatttgtcaggaaatcagtatattgtgtgatgtgctggccacccac
gatggacagagcatagacatctcctttcctgtcttcatggcggtaaccaatgtcatctcc
ttgatctgcttcaattcctcctacaaggatggggcccctgagttgaagatcgtagagact
tacaacgaaggcattgtagaagccctgggcaaggagaacctggtagacatgttcccctgg
ttgaagattttccccaacaaatctctggaaaaattaaagacctatgttaaattacgaaat
gatctgctgaataaaataattggaaattacaaggagaaattccacagcgactctatcacc
agcatgctggacgtgctgatgcaagcgaagaagaacgcagataacggcaatgccagccca
gatcaagacgcagagctgctttcagataaccacattctcaccaccgtaggggacatcttt
ggggccggcgtggagaccaccacctctgtggtcaagtggatcgtggcctacctcctgcac
aatcctcaggtgaagaagaagctctacgatgagattgaccagaatgtaggtttcagccgc
acaccaactgtcagtgaccgtaactgtctgctcctgctggaggccaccatccgagaggtg
cttcgcatcaggcccgtggcccctatgctcatcccccacaaggccaacgttgacaccagc
atcggtgagtttgctgtggacaagggcacccatgttatcatcaatctgtgggcgctgcat
cacagtgaggagtggcaccagccagacaagttcatgcctgagcgtttcttgaatcaagcg
ggaacccagctcatctcaccgacattaagctacttgcccttcggagcaggacctcgctcc
tgtataggtgagatcctggcccgccaggagctcttcctcatcatggcctggatgctgcag
aggttcgacctggaggtgccagatgatggggaactgccctccctggaaggcaaccccaag
gtggtctttatgatcgactctttcaaagtgaagatcaaggtgcgccaggcctggagggaa
gcccaggctgagggtagcacctaa
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