KEGG   Callithrix jacchus (white-tufted-ear marmoset): 100406544
Entry
100406544         CDS       T03264                                 

Gene name
GAB1
Definition
(RefSeq) GRB2 associated binding protein 1
  KO
K09593  GRB2-associated-binding protein 1
Organism
cjc  Callithrix jacchus (white-tufted-ear marmoset)
Pathway
cjc01521  EGFR tyrosine kinase inhibitor resistance
cjc04012  ErbB signaling pathway
cjc04014  Ras signaling pathway
cjc04072  Phospholipase D signaling pathway
cjc04722  Neurotrophin signaling pathway
cjc05100  Bacterial invasion of epithelial cells
cjc05205  Proteoglycans in cancer
cjc05211  Renal cell carcinoma
cjc05225  Hepatocellular carcinoma
cjc05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:cjc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    100406544 (GAB1)
   04014 Ras signaling pathway
    100406544 (GAB1)
   04072 Phospholipase D signaling pathway
    100406544 (GAB1)
 09150 Organismal Systems
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    100406544 (GAB1)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    100406544 (GAB1)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    100406544 (GAB1)
   05226 Gastric cancer
    100406544 (GAB1)
   05211 Renal cell carcinoma
    100406544 (GAB1)
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    100406544 (GAB1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100406544 (GAB1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04990 Domain-containing proteins not elsewhere classified [BR:cjc04990]
    100406544 (GAB1)
Domain-containing proteins not elsewhere classified [BR:cjc04990]
 Pleckstrin homology (PH) domain-containing proteins
  Grb-2 associated binder (Gab) family proteins
   100406544 (GAB1)
SSDB
Motif
Pfam: PH PH_11 PH_9 PH_8 PH_3 PH_13
Other DBs
NCBI-GeneID: 100406544
NCBI-ProteinID: XP_002745369
Ensembl: ENSCJAG00000002803
UniProt: F7IJR9
LinkDB
Position
3
AA seq 724 aa
MSGGEVVCSGWLRKSPPEKKLKRYAWKRRWFVLRSGRLTGDPDVLEYYKNDHAKKPIRII
DLNLCQQVDAGLTFNKKEFENSYIFDINTIDRIFYLVADSEEEMNKWVRCICDICGFNPT
EEDPVKPPGSSLQAPADLPLAINTAPPSTQADSSFATLPPPYQLINVPPHLETLGIQEDP
QDYLLLINCQSKKPEPIRTHTDSAKSTSSETDCNDNVSSHKNPASSQSKHGMNGFFQQQM
IYDSPPSRAASASVDSSLYNLPRSYSHDVLPKVSPSSTEADGELYVFNTPSGTSSLETQM
RHVSISYDIPPTPGNTYQIPRTFPEGTLGQTSKLDTIPDIPPPRPPKPHPTHDRSPVETC
SIPRTASDTDSSYCIPTAGMPPSRSNTISTVDLNKLRKDASSQDCYDIPRTFPSDRSSSL
EGFHNHFKVKNVLTVGSVSSEELDENYVPMNPNSPPRQHSSSFTEPIQEANYVPMTPGTF
DFSSFGMQVPPPAHMGFRSSPKTPPRRPVPVADCEPPPVDRNLKPDRKGQSPKILRLKPH
GLERTDSQTIGDFATRRKAKPAPLEIKPLPEWEELQAPVRSPITRSFARDSSRFPMSPRP
DSVHSTTSSSDSHDSEENYVPMNPNLSSEDPNLFGSNSLDGGSSPMVKPKGDKQVEYLDL
DLDSGKSTPPRKQKTSGSGSSVADERVDYVVVDQQKTLALKSTREAWTDGRQSTESETPT
KSVK
NT seq 2175 nt   +upstreamnt  +downstreamnt
atgagcggtggcgaagtggtctgctccggatggctccgaaagtcccccccggagaaaaag
ttgaagcgttatgcatggaagcggagatggttcgtgttacgcagtggccgtttaactgga
gatccagatgttttggaatattacaaaaatgatcatgccaagaagcctattcgtattatt
gatttaaatttatgtcaacaagtagatgctggattgacatttaacaaaaaagagtttgaa
aacagctacatttttgatatcaacactattgaccggattttctacttggtagcggatagc
gaggaggagatgaataagtgggttcgttgtatttgtgacatctgtgggtttaatcctaca
gaagaggatcctgtgaagccacctggcagctccttacaagcaccagctgatttaccttta
gctataaatacagcaccaccatccacccaggcagattcatcctttgctactctacctcct
ccgtatcagctaattaacgttccaccacacctggaaactcttggcattcaggaggatcct
caagactacctgttgctcatcaactgtcaaagcaagaagcccgaacccatcagaacacac
actgattctgcaaaatccacctcttctgaaacagactgcaatgataacgtctcttctcat
aaaaatcctgcttcttcccagagcaaacatggaatgaatggcttctttcagcagcaaatg
atatacgactctccaccttcacgtgccgcatctgcttctgtagactccagcctttataac
ctgcccaggagttattcccatgatgttttaccaaaggtgtctccatcaagtactgaagca
gatggagaactctatgtttttaacaccccctctgggacatcgagtttagagactcaaatg
aggcatgtatctattagttatgacattcctccaacacctggtaatacttatcagattcca
cgaacatttccagaaggaaccttgggacagacatcaaaactagacactattccagatatt
cctccacctcggccacctaaaccacatccaactcatgaccgatctcctgtggaaacgtgt
agtatcccacgcacggcctcggacactgacagtagttactgtatccctactgcagggatg
ccaccatcacgtagtaataccatttccactgtggatttaaacaaattgcgaaaagatgct
agttctcaagactgctatgatattccacgaacatttccaagtgatagatctagttcgctt
gaaggcttccataaccacttcaaagtcaaaaatgtgttgacagtgggaagtgtttcaagt
gaagaactggatgaaaattacgtcccaatgaatcccaactcaccgccacgacaacattcc
agcagttttacagaaccaattcaggaagcaaattatgtgccaatgactccaggaacattt
gatttttcctcatttggaatgcaagttcctcctcctgctcatatgggctttaggtcgagc
ccaaaaacccctcccagaagaccagttcctgttgcagactgtgaaccacccccagtggat
aggaacctcaagccagacagaaaaggtcaaagtcctaaaattttaagactcaaaccccat
ggtttagagcgaactgattcacaaaccataggtgactttgctacaagaagaaaggccaag
ccagcacctttagaaataaaacctttgccagaatgggaagaattacaagccccagttaga
tctcccatcactaggagttttgctcgagactcttctaggtttcccatgtccccccgaccg
gattcagtgcatagcacaacttcaagcagcgactcacatgacagtgaagagaattatgtt
cccatgaacccaaacctgtccagtgaagacccaaatctctttggtagtaacagtcttgat
ggaggaagcagccctatggtcaagcctaaaggagacaaacaggtggaatacctagatctc
gacttagattctgggaaatccacaccaccacgtaagcaaaagaccagtggctcaggcagc
agtgtagcagatgagagagtggattatgttgttgttgaccaacagaagaccttggctctc
aagagtacccgggaagcctggacagatggaagacagtccacagaatcagaaacaccaaca
aagagtgtgaaatga

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