Callithrix jacchus (white-tufted-ear marmoset): 100407532
Entry
100407532 CDS
T03264
Gene name
DOT1L
Definition
(RefSeq) DOT1 like histone lysine methyltransferase
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
cjc
Callithrix jacchus (white-tufted-ear marmoset)
Pathway
cjc00310
Lysine degradation
cjc01100
Metabolic pathways
cjc05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
cjc00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
100407532 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
100407532 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
cjc03036
]
100407532 (DOT1L)
Enzymes [BR:
cjc01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
100407532 (DOT1L)
Chromosome and associated proteins [BR:
cjc03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
100407532 (DOT1L)
HMT complexes
Dot1-containing complex
100407532 (DOT1L)
SSDB
Motif
Pfam:
DOT1
HALZ
Other DBs
NCBI-GeneID:
100407532
NCBI-ProteinID:
XP_017822755
Ensembl:
ENSCJAG00000013182
LinkDB
Position
22
AA seq
1769 aa
MEAPSPAVTYRAFAEAGFPARLELPGWSGSWWACGACPQGLGDKHHDAAHEIIETIRWVC
EEIPDLKLAMENYVLIDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSTG
LLRHILQQVYNHSVTDPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTDDDLFVDLGSG
VGQVVLQVAAATNCKHHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLS
EEWRERIANTSVIFVNNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLS
GAATIYLASRSPPPFPFHSAGLVAVLRLELSPLKGSVSWTGKPVSYYLHTIDRTILENYF
SSLKNPKLREEQEAARRRQQRESKSNAATPTKGPEGKAAGPAEAPTDSGAEEEKAGAATV
KKPSPSKARKKKLNKKGRKMAGRKRGRPKKMSTANPERKPKKNQTALDLLHAQTVSQTAA
SSPQDAYRSPHSPFYQLPPSVQRHSPNPLLVAPTPPALQKLLESFRVQYLQFLAYTKTPQ
YKASLQELLGQEKEKNAQLLGTAQQLLSHCQAQKEEIRRLFQQKLDELGVKALTYNDLIQ
AQKEISAHNQQLREQSDQLEQDNRALRSQSLQLLKARCEELQLDWATLSLEKLLKEKQAL
KSQISEKQRHCLELQISIVELEKSQRQQELLQLKSCVPPDDTLALHLRGKGALGRELEPD
AGRLHLELDCAKFPLPHLSSMSPELSMNGHAASYELCSALSRPSPKQDTPQYLASPLDQE
VVPCTPSHGGRQRVEKLSGLAVPDYTRLSPAKIVLRRHLSQDHTVPGRPAASELHPRAEH
TKENGLPYQSPSVPSSMKLSPQDPRPPSPGALQLAGEKSNEKGLRERAYGSGGEPITSLP
ISIPLSTVQPNKLPVSIPLASVVLPSRAERARSTPSPVLQPRDPSSTLEKHIGANAHSAG
SRSLALGPAGFSYGGSVAISGTLAGSPASLTPGAEPAALDESSSSGSLFATVGSRSSTPQ
HPLLLAQPRNSRPASPAHQLSSSPRLSGAAHGPLPEASKGDLPSDSGFSDPESEAKRRIV
FTIATGAGGTKQSPSSKHSPLTASTRGDCVPSHGQDSRKRGRRKRASTGTPSLTAGVSPK
RRALPSVAGLFTQPSGSPLNLNSMVSNINQPLEITAISSPEASLKSSPVPYQDHDQPPVL
KKERPLSQTNGAHYSPLTSDEEPGSEDEPSSARIERKIATISLESKSPPKTLENGGGVAG
RRPAPAGEPVNSSKWKSTFSPISDIGLAKAADSPLQAGPTLSQSSLFAFRPSLEETPADA
KLASHPRKGFPGSLSGTDGLSPSTNPANGCTFGGGLAAELSSHSFSDGASLPHKGPEAAG
LSSPLGFPSQRTKEASDANPFLSKRQLDGLAGLKGEGGRGKEVGEGGLPLCGPADKTPLP
TGKAAKARDRELDLKNGHNLFISAAAVPPGGLLSGPGLAPAASSAXGAGSSAQTHRPFLG
PFPPGPQFALGPMALQANLGSVAGSSVLQSLFSSVPAAAGLVHVSSAATRLTNSHAMGSF
SGVAGSTVGGVFNHAVPSASAHPFGARVGRGAACGSATLGPSPLQAAASASASSFQAPAS
VETRPPPPPPLPPLPPPAHLGRPPAGPPVLHALPPNAALPPPPTLLASNPEPVLLQSLAS
LPPNQAFLPSASAASLPPANASLSIKLTSLPHKGARPSFTVHHQPLPRLALAQAAPGIPQ
ASSTGPSAVWVSLGMPPPYATHLSGVKPR
NT seq
5310 nt
+upstream
nt +downstream
nt
atggaggctccatcacctgcagtcacgtaccgggcctttgcagaagcaggattccctgcc
aggctggagctcccaggctggagcggttcctggtgggcctgtggagcgtgtcctcagggg
ctcggggacaagcatcacgacgctgctcatgagatcatcgagaccatccgatgggtctgt
gaggaaatcccggatctcaagctcgctatggagaattacgttttaatcgactatgacacc
aaaagctttgagagcatgcagaggctctgtgacaagtacaaccgtgccatcgacagcatc
caccagctgtggaagggtaccacgcagcccatgaagctgaacacgcggccatccactggg
ctcctgcgccacatcctgcagcaggtctacaaccactcggtgaccgaccctgagaagctc
aacaactacgagcccttctcccccgaggtgtacggggagacctcctttgacctggtggcc
cagatgatcgacgagatcaagatgaccgacgacgacctgtttgtggacctggggagcggt
gtgggccaggttgtgctccaggtcgccgctgccaccaactgcaagcatcactatggtgtc
gagaaagcagacatcccggccaagtatgcggagaccatggaccgcgagttcaggaagtgg
atgaaatggtatggaaaaaagcatgcagaatacacattggagagaggcgatttcctctcg
gaagagtggagggagcgaattgccaacacgagtgttatatttgtgaataactttgccttt
ggtcctgaggtggatcaccagctgaaggagcgctttgcaaacatgaaggaaggtggcaga
atcgtgtcctcgaaaccctttgcacctctcaacttcagaataaacagtagaaacttgagt
ggtgcagccacgatctaccttgcttccagatctccccctcctttcccattccactcggct
gggcttgtggccgttctgaggctagagctgtcgcccctcaagggctcggtgtcgtggacg
gggaagccggtctcctactacctgcacactatcgaccgcaccatacttgaaaactatttt
tctagtctgaaaaacccaaaactcagggaggaacaggaggcagcccggcgccgccagcag
cgcgagagcaagagcaacgcagccacgcccaccaagggtcccgaaggcaaggcagctggc
cctgcggaagcccccacggactctggtgctgaggaagagaaggcgggagcagccaccgtg
aagaagccgtctccctccaaagcccgcaagaagaaactgaacaagaaggggaggaagatg
gccggccgcaagcgtgggcgccccaagaagatgagcactgcgaatcccgagcggaagccc
aagaagaaccaaactgcactggatctcctgcacgctcagaccgtgtctcagacggcggcc
tcctcgccccaggatgcctacaggtcccctcacagcccattctaccagctacctccgagc
gtgcagcggcactcccccaacccactgctggtggcgcccaccccgcccgcgctgcagaag
ctgctagagtccttcagggtccagtacctgcagttcctggcgtacacgaagaccccccag
tacaaggccagcctgcaggagctgctgggccaggagaaggagaagaacgcccagctcctg
ggcacggctcagcagctcctcagccactgtcaggcccagaaggaggagatcaggaggctg
tttcagcagaaattggatgagctgggtgtgaaggcgctgacctacaacgacctgattcag
gcgcagaaggagatctccgcccataaccagcagctgcgggagcagtcggaccagctggag
caggataaccgcgcactccgcagtcagagcctgcagctgctcaaggctcgctgtgaggag
ctgcagctggactgggccacgctgtccctggagaagctgctgaaggagaagcaggcgctg
aagagccagatctcagagaagcagaggcactgcctggagctgcagatcagcattgtggag
ctggagaagagccagcggcagcaggagctcctgcagctcaagtcctgcgtgccaccggac
gacaccctggccctgcacctgcgcgggaagggtgccctgggccgcgagctggagcccgac
gccggtcggctgcatctggagctggactgcgccaagttcccgctgcctcacttgagcagc
atgagcccagagctctccatgaatggccatgctgccagctatgagctctgcagtgcgctg
agccggccctcgcccaagcaggacacgccccagtacctggcctcacccttagaccaggag
gtggtaccctgcacccccagccacggtggccggcagcgcgtggagaagctgtctggcctg
gctgtgcccgactacaccaggctgtccccagccaagatcgtgctgaggcggcacctcagc
caggaccacacggtgcccggcaggccggccgccagcgagctgcacccgagagctgagcac
accaaggagaatggccttccctaccagagccccagcgtgcccagcagcatgaagctgagc
ccccaggacccgaggcccccatcccctggggccctgcagcttgctggagagaagagcaat
gagaagggcctgagggagcgtgcctacggcagcggcggagagcccatcaccagcctgccc
atcagcatcccgctcagcaccgtgcagccaaacaagcttccggtcagcatccccctggcc
agcgtggtgctgcccagccgtgccgagagggcgagaagcacccccagtcctgtgctgcag
ccccgagacccctcgtccacacttgaaaagcatattggtgctaatgcccacagtgctggg
agcagaagccttgccctgggccccgcaggcttctcctatggtggctcggtggccatcagc
gggaccctggcaggcagcccagcctctctcacccctggagccgagccggccgccttggat
gagtcttccagctctgggagtctttttgccactgtggggtcccgcagctccacgccacag
catcccctgctgctggcacagccccggaactcgcgcccggcctctcctgcccaccagctt
tcctccagcccccggctcagtggggctgcccacggcccgctcccggaagccagcaagggg
gacctgccctccgattccggcttctcagatccggagagcgaggccaagaggaggatcgtg
ttcaccatcgccaccggcgcgggcggcaccaagcagtcgccttccagcaaacacagcccc
ctgaccgccagcacccgcggggactgtgtgccgagccacggccaggacagtcgcaaacgt
ggccggcggaagcgagcgtcaacagggacgcccagtttgaccgcaggcgtgtcccccaag
cgccgggccctgccgtctgtcgctggccttttcacgcagccttcagggtctcctctaaac
ctcaactccatggtcagtaacatcaaccagcccctggagattacggccatctcatcccct
gaggcctccctgaagagctcccctgtgccctaccaggaccacgatcagccccccgtgctc
aagaaagagcggcccctgagccagaccaatggggcgcactactccccgctcacctccgac
gaggagccaggctctgaggacgagcccagcagcgcccgaattgagagaaaaattgcaaca
atctccttagaaagcaaatctccccccaaaaccttggaaaacggtggtggcgtggcagga
aggaggccagcacccgctggcgagcccgtcaatagcagcaagtggaagtccaccttctcg
ccgatctccgacatcggcctggccaaggctgcggacagccccttgcaggccggccccacc
ctgagccagagctccctgtttgcgttccggccctccctggaggagacccctgccgatgcc
aagctggcttcccaccccaggaaaggctttcccggctccctgtcagggaccgatggactc
agccccagcaccaaccctgcgaacggctgcaccttcggtgggggcctggccgccgagctg
agttcacacagcttcagtgatggtgcttctctcccccacaagggccccgaggcggccggc
ctgagctctccgctgggcttcccctcgcagcgcacaaaggaggcctcggacgccaaccct
ttcctgagcaagaggcagctagatggcctggctgggctgaagggcgagggtggccgcggc
aaggaggtcggggagggaggcctgccactgtgcggccctgcggacaaaaccccgctgccc
accggcaaggccgccaaggcccgggaccgcgagctcgacctcaagaacggccacaacctc
ttcatctctgcggccgccgtgcctcccggaggcctcctcagcgggcctggcctggcccca
gcggcgtcttctgcangcggcgcggggtcctctgcccagacgcaccggcccttcctgggc
cccttccctccggggccacagttcgcgctgggccccatggccctgcaggccaacctgggc
tccgtggccggctcctccgtgctgcagtcgctcttcagctctgtaccagccgccgctggc
ctggtgcacgtgtcgtccgctgccaccagactcaccaactcgcacgccatgggcagcttt
tccggggtggcaggcagcacagttggaggtgtctttaaccacgcggtgccttccgcctct
gctcatccgtttggagcccgtgtcggccgtggggctgcgtgtggcagtgccacgctgggc
ccgagcccgctgcaggcggcggccagcgcctcggcctcttcctttcaggccccggcctcg
gttgagacccggccgccccctccgcctccgcttcccccgctgcccccgcctgcgcacctg
ggccggccccccgcagggcctcccgtcctccacgctctcccacctaacgccgccttgcct
cctcccccaacgctgctggcctctaaccctgagcccgtgcttctgcagagcctcgcgtcc
ctcccgcctaaccaagctttcttgccctccgcctctgctgcctctctgccgcctgctaac
gcctctttgtctatcaagctcacctccctcccgcacaagggcgcccgcccctccttcaca
gtgcaccaccagcccctgccccggctggccctggcacaggccgcgcccgggatcccgcag
gccagcagcacagggccgtctgctgtgtgggtgtcccttggcatgccgcctccttatgcc
acgcacctctcaggggttaagccgcgataa
DBGET
integrated database retrieval system
