KEGG   Callithrix jacchus (white-tufted-ear marmoset): 100407532Help
Entry
100407532         CDS       T03264                                 

Gene name
DOT1L
Definition
(RefSeq) DOT1 like histone lysine methyltransferase
  KO
K11427  histone-lysine N-methyltransferase, H3 lysine-79 specific [EC:2.1.1.43]
Organism
cjc  Callithrix jacchus (white-tufted-ear marmoset)
Pathway
cjc00310  Lysine degradation
cjc05202  Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:cjc00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00310 Lysine degradation
    100407532 (DOT1L)
 09160 Human Diseases
  09161 Cancers: Overview
   05202 Transcriptional misregulation in cancer
    100407532 (DOT1L)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:cjc03036]
    100407532 (DOT1L)
Enzymes [BR:cjc01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.43  histone-lysine N-methyltransferase
     100407532 (DOT1L)
Chromosome and associated proteins [BR:cjc03036]
 Eukaryotic Type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     100407532 (DOT1L)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: DOT1 HALZ
Motif
Other DBs
NCBI-GeneID: 100407532
NCBI-ProteinID: XP_017822755
Ensembl: ENSCJAG00000013182
LinkDB All DBs
Position
22
AA seq 1769 aa AA seqDB search
MEAPSPAVTYRAFAEAGFPARLELPGWSGSWWACGACPQGLGDKHHDAAHEIIETIRWVC
EEIPDLKLAMENYVLIDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSTG
LLRHILQQVYNHSVTDPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTDDDLFVDLGSG
VGQVVLQVAAATNCKHHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLS
EEWRERIANTSVIFVNNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLS
GAATIYLASRSPPPFPFHSAGLVAVLRLELSPLKGSVSWTGKPVSYYLHTIDRTILENYF
SSLKNPKLREEQEAARRRQQRESKSNAATPTKGPEGKAAGPAEAPTDSGAEEEKAGAATV
KKPSPSKARKKKLNKKGRKMAGRKRGRPKKMSTANPERKPKKNQTALDLLHAQTVSQTAA
SSPQDAYRSPHSPFYQLPPSVQRHSPNPLLVAPTPPALQKLLESFRVQYLQFLAYTKTPQ
YKASLQELLGQEKEKNAQLLGTAQQLLSHCQAQKEEIRRLFQQKLDELGVKALTYNDLIQ
AQKEISAHNQQLREQSDQLEQDNRALRSQSLQLLKARCEELQLDWATLSLEKLLKEKQAL
KSQISEKQRHCLELQISIVELEKSQRQQELLQLKSCVPPDDTLALHLRGKGALGRELEPD
AGRLHLELDCAKFPLPHLSSMSPELSMNGHAASYELCSALSRPSPKQDTPQYLASPLDQE
VVPCTPSHGGRQRVEKLSGLAVPDYTRLSPAKIVLRRHLSQDHTVPGRPAASELHPRAEH
TKENGLPYQSPSVPSSMKLSPQDPRPPSPGALQLAGEKSNEKGLRERAYGSGGEPITSLP
ISIPLSTVQPNKLPVSIPLASVVLPSRAERARSTPSPVLQPRDPSSTLEKHIGANAHSAG
SRSLALGPAGFSYGGSVAISGTLAGSPASLTPGAEPAALDESSSSGSLFATVGSRSSTPQ
HPLLLAQPRNSRPASPAHQLSSSPRLSGAAHGPLPEASKGDLPSDSGFSDPESEAKRRIV
FTIATGAGGTKQSPSSKHSPLTASTRGDCVPSHGQDSRKRGRRKRASTGTPSLTAGVSPK
RRALPSVAGLFTQPSGSPLNLNSMVSNINQPLEITAISSPEASLKSSPVPYQDHDQPPVL
KKERPLSQTNGAHYSPLTSDEEPGSEDEPSSARIERKIATISLESKSPPKTLENGGGVAG
RRPAPAGEPVNSSKWKSTFSPISDIGLAKAADSPLQAGPTLSQSSLFAFRPSLEETPADA
KLASHPRKGFPGSLSGTDGLSPSTNPANGCTFGGGLAAELSSHSFSDGASLPHKGPEAAG
LSSPLGFPSQRTKEASDANPFLSKRQLDGLAGLKGEGGRGKEVGEGGLPLCGPADKTPLP
TGKAAKARDRELDLKNGHNLFISAAAVPPGGLLSGPGLAPAASSAXGAGSSAQTHRPFLG
PFPPGPQFALGPMALQANLGSVAGSSVLQSLFSSVPAAAGLVHVSSAATRLTNSHAMGSF
SGVAGSTVGGVFNHAVPSASAHPFGARVGRGAACGSATLGPSPLQAAASASASSFQAPAS
VETRPPPPPPLPPLPPPAHLGRPPAGPPVLHALPPNAALPPPPTLLASNPEPVLLQSLAS
LPPNQAFLPSASAASLPPANASLSIKLTSLPHKGARPSFTVHHQPLPRLALAQAAPGIPQ
ASSTGPSAVWVSLGMPPPYATHLSGVKPR
NT seq 5310 nt NT seq  +upstreamnt  +downstreamnt
atggaggctccatcacctgcagtcacgtaccgggcctttgcagaagcaggattccctgcc
aggctggagctcccaggctggagcggttcctggtgggcctgtggagcgtgtcctcagggg
ctcggggacaagcatcacgacgctgctcatgagatcatcgagaccatccgatgggtctgt
gaggaaatcccggatctcaagctcgctatggagaattacgttttaatcgactatgacacc
aaaagctttgagagcatgcagaggctctgtgacaagtacaaccgtgccatcgacagcatc
caccagctgtggaagggtaccacgcagcccatgaagctgaacacgcggccatccactggg
ctcctgcgccacatcctgcagcaggtctacaaccactcggtgaccgaccctgagaagctc
aacaactacgagcccttctcccccgaggtgtacggggagacctcctttgacctggtggcc
cagatgatcgacgagatcaagatgaccgacgacgacctgtttgtggacctggggagcggt
gtgggccaggttgtgctccaggtcgccgctgccaccaactgcaagcatcactatggtgtc
gagaaagcagacatcccggccaagtatgcggagaccatggaccgcgagttcaggaagtgg
atgaaatggtatggaaaaaagcatgcagaatacacattggagagaggcgatttcctctcg
gaagagtggagggagcgaattgccaacacgagtgttatatttgtgaataactttgccttt
ggtcctgaggtggatcaccagctgaaggagcgctttgcaaacatgaaggaaggtggcaga
atcgtgtcctcgaaaccctttgcacctctcaacttcagaataaacagtagaaacttgagt
ggtgcagccacgatctaccttgcttccagatctccccctcctttcccattccactcggct
gggcttgtggccgttctgaggctagagctgtcgcccctcaagggctcggtgtcgtggacg
gggaagccggtctcctactacctgcacactatcgaccgcaccatacttgaaaactatttt
tctagtctgaaaaacccaaaactcagggaggaacaggaggcagcccggcgccgccagcag
cgcgagagcaagagcaacgcagccacgcccaccaagggtcccgaaggcaaggcagctggc
cctgcggaagcccccacggactctggtgctgaggaagagaaggcgggagcagccaccgtg
aagaagccgtctccctccaaagcccgcaagaagaaactgaacaagaaggggaggaagatg
gccggccgcaagcgtgggcgccccaagaagatgagcactgcgaatcccgagcggaagccc
aagaagaaccaaactgcactggatctcctgcacgctcagaccgtgtctcagacggcggcc
tcctcgccccaggatgcctacaggtcccctcacagcccattctaccagctacctccgagc
gtgcagcggcactcccccaacccactgctggtggcgcccaccccgcccgcgctgcagaag
ctgctagagtccttcagggtccagtacctgcagttcctggcgtacacgaagaccccccag
tacaaggccagcctgcaggagctgctgggccaggagaaggagaagaacgcccagctcctg
ggcacggctcagcagctcctcagccactgtcaggcccagaaggaggagatcaggaggctg
tttcagcagaaattggatgagctgggtgtgaaggcgctgacctacaacgacctgattcag
gcgcagaaggagatctccgcccataaccagcagctgcgggagcagtcggaccagctggag
caggataaccgcgcactccgcagtcagagcctgcagctgctcaaggctcgctgtgaggag
ctgcagctggactgggccacgctgtccctggagaagctgctgaaggagaagcaggcgctg
aagagccagatctcagagaagcagaggcactgcctggagctgcagatcagcattgtggag
ctggagaagagccagcggcagcaggagctcctgcagctcaagtcctgcgtgccaccggac
gacaccctggccctgcacctgcgcgggaagggtgccctgggccgcgagctggagcccgac
gccggtcggctgcatctggagctggactgcgccaagttcccgctgcctcacttgagcagc
atgagcccagagctctccatgaatggccatgctgccagctatgagctctgcagtgcgctg
agccggccctcgcccaagcaggacacgccccagtacctggcctcacccttagaccaggag
gtggtaccctgcacccccagccacggtggccggcagcgcgtggagaagctgtctggcctg
gctgtgcccgactacaccaggctgtccccagccaagatcgtgctgaggcggcacctcagc
caggaccacacggtgcccggcaggccggccgccagcgagctgcacccgagagctgagcac
accaaggagaatggccttccctaccagagccccagcgtgcccagcagcatgaagctgagc
ccccaggacccgaggcccccatcccctggggccctgcagcttgctggagagaagagcaat
gagaagggcctgagggagcgtgcctacggcagcggcggagagcccatcaccagcctgccc
atcagcatcccgctcagcaccgtgcagccaaacaagcttccggtcagcatccccctggcc
agcgtggtgctgcccagccgtgccgagagggcgagaagcacccccagtcctgtgctgcag
ccccgagacccctcgtccacacttgaaaagcatattggtgctaatgcccacagtgctggg
agcagaagccttgccctgggccccgcaggcttctcctatggtggctcggtggccatcagc
gggaccctggcaggcagcccagcctctctcacccctggagccgagccggccgccttggat
gagtcttccagctctgggagtctttttgccactgtggggtcccgcagctccacgccacag
catcccctgctgctggcacagccccggaactcgcgcccggcctctcctgcccaccagctt
tcctccagcccccggctcagtggggctgcccacggcccgctcccggaagccagcaagggg
gacctgccctccgattccggcttctcagatccggagagcgaggccaagaggaggatcgtg
ttcaccatcgccaccggcgcgggcggcaccaagcagtcgccttccagcaaacacagcccc
ctgaccgccagcacccgcggggactgtgtgccgagccacggccaggacagtcgcaaacgt
ggccggcggaagcgagcgtcaacagggacgcccagtttgaccgcaggcgtgtcccccaag
cgccgggccctgccgtctgtcgctggccttttcacgcagccttcagggtctcctctaaac
ctcaactccatggtcagtaacatcaaccagcccctggagattacggccatctcatcccct
gaggcctccctgaagagctcccctgtgccctaccaggaccacgatcagccccccgtgctc
aagaaagagcggcccctgagccagaccaatggggcgcactactccccgctcacctccgac
gaggagccaggctctgaggacgagcccagcagcgcccgaattgagagaaaaattgcaaca
atctccttagaaagcaaatctccccccaaaaccttggaaaacggtggtggcgtggcagga
aggaggccagcacccgctggcgagcccgtcaatagcagcaagtggaagtccaccttctcg
ccgatctccgacatcggcctggccaaggctgcggacagccccttgcaggccggccccacc
ctgagccagagctccctgtttgcgttccggccctccctggaggagacccctgccgatgcc
aagctggcttcccaccccaggaaaggctttcccggctccctgtcagggaccgatggactc
agccccagcaccaaccctgcgaacggctgcaccttcggtgggggcctggccgccgagctg
agttcacacagcttcagtgatggtgcttctctcccccacaagggccccgaggcggccggc
ctgagctctccgctgggcttcccctcgcagcgcacaaaggaggcctcggacgccaaccct
ttcctgagcaagaggcagctagatggcctggctgggctgaagggcgagggtggccgcggc
aaggaggtcggggagggaggcctgccactgtgcggccctgcggacaaaaccccgctgccc
accggcaaggccgccaaggcccgggaccgcgagctcgacctcaagaacggccacaacctc
ttcatctctgcggccgccgtgcctcccggaggcctcctcagcgggcctggcctggcccca
gcggcgtcttctgcangcggcgcggggtcctctgcccagacgcaccggcccttcctgggc
cccttccctccggggccacagttcgcgctgggccccatggccctgcaggccaacctgggc
tccgtggccggctcctccgtgctgcagtcgctcttcagctctgtaccagccgccgctggc
ctggtgcacgtgtcgtccgctgccaccagactcaccaactcgcacgccatgggcagcttt
tccggggtggcaggcagcacagttggaggtgtctttaaccacgcggtgccttccgcctct
gctcatccgtttggagcccgtgtcggccgtggggctgcgtgtggcagtgccacgctgggc
ccgagcccgctgcaggcggcggccagcgcctcggcctcttcctttcaggccccggcctcg
gttgagacccggccgccccctccgcctccgcttcccccgctgcccccgcctgcgcacctg
ggccggccccccgcagggcctcccgtcctccacgctctcccacctaacgccgccttgcct
cctcccccaacgctgctggcctctaaccctgagcccgtgcttctgcagagcctcgcgtcc
ctcccgcctaaccaagctttcttgccctccgcctctgctgcctctctgccgcctgctaac
gcctctttgtctatcaagctcacctccctcccgcacaagggcgcccgcccctccttcaca
gtgcaccaccagcccctgccccggctggccctggcacaggccgcgcccgggatcccgcag
gccagcagcacagggccgtctgctgtgtgggtgtcccttggcatgccgcctccttatgcc
acgcacctctcaggggttaagccgcgataa

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