Corynebacterium sp. ATCC 6931: DR71_1956
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Entry
DR71_1956 CDS
T03283
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase, large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
coa
Corynebacterium sp. ATCC 6931
Pathway
coa00290
Valine, leucine and isoleucine biosynthesis
coa00660
C5-Branched dibasic acid metabolism
coa01100
Metabolic pathways
coa01110
Biosynthesis of secondary metabolites
coa01210
2-Oxocarboxylic acid metabolism
coa01230
Biosynthesis of amino acids
Module
coa_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
coa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
DR71_1956 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
DR71_1956 (leuC)
Enzymes [BR:
coa01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
DR71_1956 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
DR71_1956 (leuC)
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Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
AIN81992
UniProt:
A0A088QF21
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Position
2205522..2206949
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AA seq
475 aa
AA seq
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MRTTDTSPKTLAEKVWRDHVVKQGENGEPDLIYIDLHLVHEVTSPQAFDGLRLAGRKVRR
PDLTIATEDHNVPTTVAGGQIDLIEEPTSRTQIATLRKNAEEFGIRLHPMGDREQGIVHV
VGPQLGLTQPGTTVVCGDSHTATHGAFGAMAFGIGTSEVEHVLATQTLPLKPFKTMAVNV
TGELQDGVTAKDLILAIIAKIGTGGGQGHVIEYRGEAIEKLSMEARMTICNMSIEAGARA
GMIAPDETTFEYLKGRPHAPQGEQWDEAVEYWKSLVTDEDAEFDKVVEIDGSALTPFVTW
GTNPGQGVPLGETVPDPEFIAEDSDRIAAERALEYMDLKPGTPMRDVKVNVVFVGSCTNG
RIEDMRAVADVLKDRKVADGVQMLIVPGSAKVRAQAEEEGLGKIFEEAGAEWRMPGCSMC
LGMNPDQLTPGQRCASTSNRNFEGRQGKGGRTHLVSPAVAAATAVAGHFAAPADL
NT seq
1428 nt
NT seq
+upstream
nt +downstream
nt
atgcgcaccacggacactagcccgaagactctggccgagaaagtctggcgtgaccacgtt
gtcaagcaaggcgaaaacggcgaaccagatctgatttatatcgatctgcacctcgtccac
gaggttacctcgccgcaggcttttgatggcctccgtctggcagggcgcaaggtgcgccgc
ccggatctgaccatcgcaaccgaggaccacaacgttccgacgactgtagccggtggccag
attgatttaattgaggaaccgacctctcgcacccagattgccacattgcgcaagaatgcc
gaagagttcggaatccgcctgcatccgatgggcgaccgtgaacagggcatcgtgcacgtt
gtcggtccgcagctgggcctgactcaaccgggcaccaccgttgtctgtggtgactcccac
actgcaacgcacggtgctttcggcgcgatggcctttggtatcggtacttccgaagttgag
cacgttctggctacccagaccctgccactgaagccttttaagaccatggcggtcaatgtc
accggcgagctgcaggatggtgttaccgccaaggacctgattctggcgattatcgccaag
attggtaccggtggtggccagggccatgttatcgagtaccgtggcgaggccatcgagaag
ctgtcgatggaagcccgcatgaccatctgcaacatgtccatcgaggccggtgcccgcgcc
ggcatgatcgctccagacgaaaccaccttcgagtacctgaagggccgcccgcacgcgccg
cagggcgagcagtgggacgaggcggtcgagtactggaagtccctggttaccgacgaggat
gcagagttcgacaaggtcgtcgaaatcgacggttccgcgctgactccattcgttacctgg
ggtaccaacccgggccagggcgtgccgctgggggagaccgtgccggatccggagttcatc
gccgaggactccgaccgcatcgccgccgagcgcgcactagagtacatggatctgaagccg
ggcaccccgatgcgcgatgtcaaggtcaacgtggtcttcgtaggttcctgcaccaacggc
cgcatcgaggacatgcgcgccgtcgccgacgtgctgaaggaccgcaaggttgccgacggc
gtccagatgctcatcgtgccgggctccgcaaaggtccgcgcgcaggctgaggaagaggga
ctgggcaagatcttcgaagaggcaggcgctgaatggcgtatgccaggctgttccatgtgc
cttggcatgaacccggaccagctgaccccgggccagcgttgcgcttcgacctccaaccgc
aacttcgaaggtcgccaaggtaagggtggtcgtacccacctggtcagcccggctgtcgcc
gcagctaccgccgtcgccggtcacttcgcagcgccggctgatctctaa
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