Cynoglossus semilaevis (tongue sole): 103376789 Help Entry 103376789         CDS       T04866                                  Definition (RefSeq) transforming growth factor beta-3   KO K13377   transforming growth factor beta-3 Organism csem  Cynoglossus semilaevis (tongue sole) Pathway csem04010   MAPK signaling pathway csem04060   Cytokine-cytokine receptor interaction csem04068   FoxO signaling pathway csem04110   Cell cycle csem04218   Cellular senescence csem04350   TGF-beta signaling pathway Brite KEGG Orthology (KO) [BR:csem00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     103376789    04350 TGF-beta signaling pathway     103376789    04068 FoxO signaling pathway     103376789   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     103376789  09140 Cellular Processes   09143 Cell growth and death    04110 Cell cycle     103376789    04218 Cellular senescence     103376789  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:csem04052]     103376789 Cytokines and growth factors [BR:csem04052]  Cytokines   Transforming growth factors (RSTK binding)    103376789 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  TGFb_propeptide TGF_beta Motif Other DBs NCBI-GeneID:  103376789 NCBI-ProteinID:  XP_008305524 UniProt:  A0A3P8UCA4 LinkDB All DBs Position 1 AA seq 403 aa AA seqDB search MNLGKALLFFLLSNFVTMTLSLSTCTTVDIDHIKKKRVEAVRGQILSKLRLTSPPQTTGP SQVPYQVLALYNSTKELIEELGRDRQQSCGQDNTETEYYAKEIYKFNMINGPPENNDLSY CPKSVTSKVFRFNVSIMEKNSTNLFRAEFRALRIPNPVAKGNEQRIELYQILQKDDPKAK QRYIGGKNVLTKGTPEWVSFDVTQTVREWLMYRQTNLGLEISVHCPCHTFRPNGDIIENT NEVLEVKFKGMEPEYEERKFKPKEQLYPHLILMMLPPHRLDAQSSSRRRKRALDTNYCFN NYEENCCVRPLYINFRQDLGWKWIHQPEGYYANFCSGPCPYLRSADTTHSSLLSLYNTLN PEASASPCCVPQDLEPLTILYYVGRSPKVEQLSNMVVKSCKCS NT seq 1212 nt NT seq  +upstreamnt  +downstreamnt atgaatctgggaaaagcgctcctgtttttcctcctgtccaactttgtgacgatgactctg tcgctgtccacctgcaccaccgtggacattgaccacataaagaaaaagagagtggaggcg gtgaggggacagattcttagtaaactgcgactgaccagtccgccgcagaccacaggtcca agtcaggtaccgtaccaggttctggccctttataacagtaccaaggagctgatcgaggag ctgggcagagacagacagcagagctgtgggcaggataacacggagaccgagtactacgcc aaagagatttacaagttcaacatgatcaatggtccgccagaaaacaatgacctttcctac tgccccaagagtgtcacctccaaggtgttccgcttcaacgtgtccatcatggagaagaac tccaccaacttgttccgggcagagtttcgagctctgcggatccccaaccccgttgccaag ggaaacgagcagaggatcgagctctaccagatcctccagaaagacgatcccaaagccaaa cagcgctacatcggaggcaagaatgtcctgaccaagggaacgcctgagtgggtctccttt gatgtcacccagacagtgagggagtggctaatgtacagacagaccaaccttggcctggag atcagtgtgcactgcccctgccataccttcaggcctaatggagacattattgagaacacc aacgaggtgctggaggtcaagttcaaaggtatggaaccagaatacgaggaaagaaagttc aaaccaaaggagcagctctaccctcacctcatcctcatgatgctgccaccccacaggctg gacgcccagtcctcgtcccgtaggcgcaagagggcacttgacaccaattactgcttcaac aattacgaggagaactgctgcgtgcgaccactatatattaacttccgtcaagatctggga tggaagtggatccatcagcctgaaggctactatgccaacttctgttccggtccgtgtcct tatctacgcagcgctgacaccacccacagctcgctgctgagcctctacaacaccctgaac ccggaagcctccgcctcgccctgctgtgttcctcaggacttggagcccctgaccatcctg tactacgtgggtcgctccccaaaagtcgagcagctctcaaacatggttgtcaagtcctgc aagtgcagctag

Cynoglossus semilaevis (tongue sole): 103377845 Help Entry 103377845         CDS       T04866                                  Definition (RefSeq) transforming growth factor beta-1   KO K13375   transforming growth factor beta-1 Organism csem  Cynoglossus semilaevis (tongue sole) Pathway csem04010   MAPK signaling pathway csem04060   Cytokine-cytokine receptor interaction csem04068   FoxO signaling pathway csem04110   Cell cycle csem04218   Cellular senescence csem04350   TGF-beta signaling pathway csem04672   Intestinal immune network for IgA production Brite KEGG Orthology (KO) [BR:csem00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     103377845    04350 TGF-beta signaling pathway     103377845    04068 FoxO signaling pathway     103377845   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     103377845  09140 Cellular Processes   09143 Cell growth and death    04110 Cell cycle     103377845    04218 Cellular senescence     103377845  09150 Organismal Systems   09151 Immune system    04672 Intestinal immune network for IgA production     103377845  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03110 Chaperones and folding catalysts [BR:csem03110]     103377845   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:csem04052]     103377845    00536 Glycosaminoglycan binding proteins [BR:csem00536]     103377845 Chaperones and folding catalysts [BR:csem03110]  Intramolecular chaperones   Others    103377845 Cytokines and growth factors [BR:csem04052]  Cytokines   Transforming growth factors (RSTK binding)    103377845 Glycosaminoglycan binding proteins [BR:csem00536]  Heparan sulfate / Heparin   Growth factors/receptors    103377845 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  TGFb_propeptide TGF_beta Motif Other DBs NCBI-GeneID:  103377845 NCBI-ProteinID:  XP_008307032 UniProt:  A0A3P8V3J3 LinkDB All DBs Position 4 AA seq 386 aa AA seqDB search MKLALLMLTVVYMVGSVSSMSTCKTVDLEMVKKKRIEAIRSQILSKLRLPKEPEEDQAGD QEAIPLTLLSLYNSTKEMLKEQQTGAQTVISTEQEEEEYFAKVLHKFNMTNTGTDMKDKK SIEFLFNLSNIRQSVGDYHLLTRAELRLLIKTPNIATKQRVELYTGLGSSPEYLTTRFIT TNLKDKWLSFDVTETLQNWLKGNETEQGFQLWVFCGCNNDPSMENTFKFSISGVSFGRGD TQTLEALTKQPPYILTMSIPQNVSSHITSRKKRATDGKADTCTTQTETCCVRSLYINFRK DLGWKWIHEPTGYHANYCMGSCTYIWNAENKYSQILALYKHHNPGASAQPCCVPQALEPL AIIYYVGRQHKVEQLSNMSVTSCKCS NT seq 1161 nt NT seq  +upstreamnt  +downstreamnt atgaagctcgcgctgttgatgcttacggtggtgtacatggtgggcagtgtgagcagcatg tccacatgtaagactgtagacctggagatggtgaagaagaagcggatcgaagccatcagg agccagatcctcagcaagctgcgtcttcccaaggagccggaggaggatcaggctggagac caggaggcgatccctttgactctgctctccctctacaacagcaccaaggagatgttgaag gagcagcagacgggggcccagacggtcatctccacagagcaggaggaggaggagtacttc gccaaggtcctgcacaagttcaacatgaccaatacaggtacagacatgaaggacaagaaa agcatcgaattcctcttcaacctctctaatataaggcaaagtgttggggattaccacctg ctgaccagagccgagctgcggttgcttatcaagacaccgaacatagcgacaaagcagcgg gttgagctctacacgggcctgggatcctcacccgagtacctcactactcgcttcatcact actaatctgaaggacaagtggctatcttttgatgtgactgagaccctgcagaactggctc aaagggaatgagaccgagcagggtttccagctctgggtcttctgtggttgcaacaacgac ccaagtatggaaaacacgttcaagttttctatctctggggtctcttttgggaggggagac acacagacgcttgaggcgttgacgaaacaaccaccatatatcctgaccatgtccattcct caaaacgtcagcagccacatcacctcccgcaaaaaacgggccacagatgggaaagcagat acatgtactacccagacggagacctgctgtgtgcgaagcttgtacatcaatttccggaaa gacctgggctggaagtggatacacgaaccgacgggctaccacgccaactactgcatgggc tcctgcacctacatctggaacgcagaaaacaaatattctcagattttggctctgtataag catcacaacccaggagcctctgcccagccctgctgtgttccccaggcactggaaccactg gcaatcatatactatgtcggcaggcagcacaaggtggagcaactgtccaatatgagcgta acgtcctgcaagtgtagctaa

Cynoglossus semilaevis (tongue sole): 103380810 Help Entry 103380810         CDS       T04866                                  Definition (RefSeq) transforming growth factor beta-3-like   KO K13377   transforming growth factor beta-3 Organism csem  Cynoglossus semilaevis (tongue sole) Pathway csem04010   MAPK signaling pathway csem04060   Cytokine-cytokine receptor interaction csem04068   FoxO signaling pathway csem04110   Cell cycle csem04218   Cellular senescence csem04350   TGF-beta signaling pathway Brite KEGG Orthology (KO) [BR:csem00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     103380810    04350 TGF-beta signaling pathway     103380810    04068 FoxO signaling pathway     103380810   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     103380810  09140 Cellular Processes   09143 Cell growth and death    04110 Cell cycle     103380810    04218 Cellular senescence     103380810  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:csem04052]     103380810 Cytokines and growth factors [BR:csem04052]  Cytokines   Transforming growth factors (RSTK binding)    103380810 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  TGFb_propeptide TGF_beta Motif Other DBs NCBI-GeneID:  103380810 NCBI-ProteinID:  XP_008311127 UniProt:  A0A3P8WZ10 LinkDB All DBs Position 7 AA seq 409 aa AA seqDB search MHLGKAVLFVLLLNCATLSSCLSTCATVDIDHVKRKRVEAIRGQILSKLRLTSPPHSLGP SKIPYQIQALYNSTKELLEQLGRDRQQSCGQDNTETEYYAKEIYKFDMVTPESNDVHYCV KGSTSKVFRFNVSAMERNSTNLFRAEFRALRMPNQSAKKNEQRIELYQILRPNEHITKQR YIAAKNVLTRGTPEWVSFDVTETVREWLYNRGSNLGLEISVHCPCHTFNPNGDIIDDEKE VLEVKFKGVDGEEEPSRWDQEQKKDPKNQKQQVLPHLILMMIPPHRLETQHTRRRKRGLD SNYCFSSTEQSCCVRKLHIDFRRDLDWKWIHEPSGYEANYCSGPCPYLRSADSTHSSLLG LYNTLNPDASAAPCCVPQDLEPLTILYYSGRTPKVEQLSNMIVKSCKCS NT seq 1230 nt NT seq  +upstreamnt  +downstreamnt atgcatttgggtaaagctgtgctgttcgtcctcctcctcaactgcgcaacgttgagctcc tgcctgtcaacctgcgccaccgtggacattgaccacgtgaagaggaagagggtggaggcg ataagaggtcagattctgagcaaactgagactgaccagtcctccacactcactgggaccc agtaagatcccctaccagatccaggcgctgtacaacagcaccaaggagctcctggagcag ctcggcagggaccggcagcagagctgcggtcaggacaacacagagacagagtactatgcc aaagagatttataaattcgacatggtgacgccggagagtaacgatgtgcactattgtgta aaaggcagcacctcaaaggtttttcgcttcaacgtctctgccatggaaaggaactcgacc aacctcttcagggcagagttccgtgctctgaggatgccaaaccagagtgccaagaagaac gaacagaggattgagctctaccagatcctgaggccaaacgaacacatcacaaaacagcgc tacattgcagctaagaatgtgctgaccagaggaactccagaatgggtgtccttcgatgtg actgaaactgtgagggaatggctgtacaacagaggaagtaatctggggctggagatcagt gttcactgcccctgccacaccttcaaccctaatggtgacatcatcgacgatgagaaggag gtgctggaggtgaaattcaaaggtgtggatggagaggaggagccgagtcgttgggatcag gagcagaagaaggacccaaagaatcaaaaacaacaggtcctgcctcacctcatcctcatg atgatcccaccacaccgtttagagactcagcacacacgccgacgcaagagaggcctggac tcaaactactgtttctcaagcactgagcaaagctgctgtgttcgtaaacttcacattgat ttccgtcgtgacctggactggaagtggatccatgagcccagtggttatgaggccaactac tgctctgggccctgcccttatctgaggagcgcagactccacacacagctcattgttgggt ctgtacaacaccctgaacccagacgcgtcggccgccccctgctgtgttcctcaagaccta gaacctctgacgatactctactactctggacggaccccgaaagtggagcagctctcaaac atgatcgtcaagtcctgcaagtgtagctga

Cynoglossus semilaevis (tongue sole): 103388748 Help Entry 103388748         CDS       T04866                                  Gene name tgfb2 Definition (RefSeq) transforming growth factor beta-2   KO K13376   transforming growth factor beta-2 Organism csem  Cynoglossus semilaevis (tongue sole) Pathway csem04010   MAPK signaling pathway csem04060   Cytokine-cytokine receptor interaction csem04068   FoxO signaling pathway csem04110   Cell cycle csem04218   Cellular senescence csem04350   TGF-beta signaling pathway Brite KEGG Orthology (KO) [BR:csem00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     103388748 (tgfb2)    04350 TGF-beta signaling pathway     103388748 (tgfb2)    04068 FoxO signaling pathway     103388748 (tgfb2)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     103388748 (tgfb2)  09140 Cellular Processes   09143 Cell growth and death    04110 Cell cycle     103388748 (tgfb2)    04218 Cellular senescence     103388748 (tgfb2)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:csem04052]     103388748 (tgfb2)    00536 Glycosaminoglycan binding proteins [BR:csem00536]     103388748 (tgfb2) Cytokines and growth factors [BR:csem04052]  Cytokines   Transforming growth factors (RSTK binding)    103388748 (tgfb2) Glycosaminoglycan binding proteins [BR:csem00536]  Heparan sulfate / Heparin   Growth factors/receptors    103388748 (tgfb2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  TGFb_propeptide TGF_beta SPEG_u2 Motif Other DBs NCBI-GeneID:  103388748 NCBI-ProteinID:  XP_008322101 UniProt:  A0A3P8VQE7 LinkDB All DBs Position 13 AA seq 409 aa AA seqDB search MNLCVVSLLLTLDLATVAFSLSTCSTLDMDQFKKKRIRAIRGQILSKLKLTSPPEEYPEP EEVSRDIVAIYNSTRDLLLEKANERAATCERQRSEEEYYAKEVYKIDMQPFYPSENVISP THLNPYFRRLTFDVSSMEKNASNLVKAELRIFRLQNPAARVSEQRIELYQILGHKDLTSP TQRYIDSKVVRTQTEGEWLSFDVTEAVSEWLNHRDRNSGFKISLHCPCCTFVPSNNYIIP NKSEELEARFAGIDDSFIHGGDKRRRHSARAPHLLLMLLPTYRLESQSQHKSHRSKRALD AAYCSKNVQDNCCLRSLYIDFKKDLGWRWIYEPKGYEANFCAGACPYLWSADTQHTKVLG LYNSINPEASASPCCVSQDLEPLTILYYIGKTPKIEQLSNMKVKSCKCS NT seq 1230 nt NT seq  +upstreamnt  +downstreamnt atgaacctgtgtgtagtcagtcttctcctcactttggatctagccaccgtggcgttcagt ctgtccacatgcagtacgctggacatggatcagttcaagaagaagcgcatccgggccatc cggggccagatcctgagcaagctgaagctcaccagtccgccagaggagtacccagagccg gaggaggtgtcccgggacattgtggccatatacaacagcaccagagacctgctgctggag aaagccaacgaacgggcagcgacgtgtgagcggcagcgcagcgaggaggagtactacgcc aaggaggtgtacaagattgacatgcagcccttttacccatcagagaatgtcatctctcct acacacctcaacccctacttcaggcggctgacattcgatgtctcctccatggagaagaac gcgtccaacctggtgaaggctgagctcagaatctttcgtcttcagaaccctgctgctcga gtttctgagcagcgcattgagctctaccagatattaggacacaaagacttgacatcgcca acgcagcgatacatcgacagcaaagtggtgcgaacgcagacagagggagagtggctgtcc tttgacgtcacagaggcagtgagtgagtggctgaaccacagagacagaaacagtggattt aaaatcagcctgcattgtccctgctgcacgttcgtaccatcaaataattatattattccc aacaagagcgaggagctggaggcacgtttcgcaggcattgatgacagcttcattcatggt ggtgataagaggcggcgacacagcgctcgggctccgcacctcctcctcatgcttctgcct acataccgtctggagtctcagtcccagcacaagagccatcgatccaagagagccctggat gctgcctactgctccaaaaatgtgcaggacaactgctgcttacgctcactctacatcgat tttaaaaaggacttgggctggaggtggatctatgaaccaaagggatatgaggccaacttc tgtgccggggcgtgtccttatctgtggagtgccgacacccagcatactaaggtgttaggc ctctacaattccataaaccctgaagcctctgcctcaccctgctgtgtctcccaggacctg gagcccctcaccatcctctactacatcggcaaaacccctaaaatagagcagctctccaac atgaaggtcaagtcctgcaagtgcagctag

Cynoglossus semilaevis (tongue sole): 103390834 Help Entry 103390834         CDS       T04866                                  Definition (RefSeq) transforming growth factor beta-2-like   KO K13376   transforming growth factor beta-2 Organism csem  Cynoglossus semilaevis (tongue sole) Pathway csem04010   MAPK signaling pathway csem04060   Cytokine-cytokine receptor interaction csem04068   FoxO signaling pathway csem04110   Cell cycle csem04218   Cellular senescence csem04350   TGF-beta signaling pathway Brite KEGG Orthology (KO) [BR:csem00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     103390834    04350 TGF-beta signaling pathway     103390834    04068 FoxO signaling pathway     103390834   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     103390834  09140 Cellular Processes   09143 Cell growth and death    04110 Cell cycle     103390834    04218 Cellular senescence     103390834  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:csem04052]     103390834    00536 Glycosaminoglycan binding proteins [BR:csem00536]     103390834 Cytokines and growth factors [BR:csem04052]  Cytokines   Transforming growth factors (RSTK binding)    103390834 Glycosaminoglycan binding proteins [BR:csem00536]  Heparan sulfate / Heparin   Growth factors/receptors    103390834 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  TGFb_propeptide TGF_beta Motif Other DBs NCBI-GeneID:  103390834 NCBI-ProteinID:  XP_008325099 UniProt:  A0A3P8V4C6 LinkDB All DBs Position 15 AA seq 421 aa AA seqDB search MWLPRLALLLLLRFSSLPSPGAEGLNTCQSINLDAQKSRRIEAVRGQILSKLRIRSPPKD DEAPVPGPVPPEVMLLYNSTRELLKERARQAESACERESSEEDYYAKEVQRIDMLPTRTT TNAVQPVAPSPHYRVVQFDVSGVDLTNSTLVMAEFRIFRAPNPQARASEQRVEIYQLLKP DEESTSTQRYIDSRTVQPKAKGSWMSVDVTETVKDWLSDPENNLGLKLGVHCPCCTFVPS TNNIVPNKSEELEALFAGVDDEKIRQIRKPGQVKGQPDVSTKTPHLILTLLPSDRVDNPA KKNRKKRAAATDASTCSRGSDQGCCLRSLYIDFRRDLNWKWIHEPKGYKANFCAGNCPYL WSANNHYNMILPLYNKLNPEASASPCCVPQDLEPLTIMYFIGRTPRVEQLSNMVVKSCKC R NT seq 1266 nt NT seq  +upstreamnt  +downstreamnt atgtggctgccccgcctggcactgctgcttctgctccggttctccagtttaccgtcgccg ggggcggaggggctcaacacgtgtcagtccatcaacttggacgcacagaagtcccggcgc atcgaggcggtgcggggacagattctcagtaaactccgcatccgcagtcctccaaaagat gacgaggccccggtgcctggacccgtgccaccggaagtgatgttgctctacaacagtaca cgagagctgctgaaggagcgcgcgcgccaggccgagtctgcctgcgagcgcgagagcagc gaagaggattattacgccaaagaggtgcagaggattgacatgctgccaacacgcaccacc acaaacgctgtgcagccagtagcacccagcccccactacagagtcgtccagttcgacgtc agtggagtggacttgaccaacagcaccttggtcatggctgagttcagaatcttcagggct cccaatccccaggcccgggcttcagagcagagagtggagatctatcagctgctgaagcca gatgaggagagcacctccactcaacgttacatcgactcccgcaccgttcagcccaaagca aagggatcttggatgtctgtggacgtcacagaaaccgttaaggactggttgtcagatcca gaaaataatctgggcctaaaactaggtgtccactgtccgtgctgcaccttcgtcccttcc accaacaacattgttcccaacaagagtgaggagctggaggccctgtttgcaggtgttgac gacgaaaagattcgccagataagaaaacccggccaggttaaaggtcagccggacgtcagc accaagacaccacacctcatcctcacactgctgcccagtgacagagtggacaacccagcc aagaagaaccgcaagaagagggctgcagccacagacgcctccacctgctcccgtggctca gaccaaggctgctgcctgcgctcgctctacatcgacttcaggcgtgacctcaactggaag tggatccatgagcctaaaggttacaaagccaacttctgtgctggcaactgtccttacctc tggagtgccaacaaccattacaacatgatcctgcccctgtacaacaagctgaaccctgag gcctcagcctcgccctgctgcgttcctcaggacctggagcctctcaccatcatgtatttc ataggccgcacgccacgtgttgagcaactctccaacatggtggtcaaatcctgcaagtgt cgctga

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